These personal tragedies will, and must, be told and heard. There is, however, also a truthful and objective scientific narrative to be written about how the virus played out and how the world set about dealing with it. Spike is that story - from the inside. Its author, Jeremy Farrar, is one of the UK's leading scientists and a ­­member of the SAGE emergency committee.As head of the Wellcome Trust, and an expert in emerging infectious diseases, Jeremy Farrar was one of the first people in the world to hear about a mysterious new respiratory disease in China - and to learn that it could readily spread between people. Farrar describes how it feels as one of the key scientists at the sharp end of a fast-moving situation, when complex decisions must be made quickly amid great uncertainty. His book casts light on the UK government's claims to be 'following the science' in its response to the virus, and is informed not just by Farrar's views but by interviews with other top scientists and political figures.Farrar, who has spent his career on the frontlines of epidemics including Nipah virus in Malaysia, bird flu in Vietnam and Ebola in West Africa, also reflects on the wider issues of Covid-19: the breath-taking scientific advances in creating tests, treatments and vaccines; the challenge to world leaders to respond for the global good and the need to address inequalities that hold back success against the virus. All these shape how the world ultimately fares not just against Covid-19, but against all the major he­­alth challenges we face globally.

    In the third edition, all the chapters have been thoroughly revised and the concepts updated. A new chapter on the spectral analysis of heart rate variability has been added. This is the first textbook in medicine to introduce this topic as a text for medical students. Apart from this, the feedback received from students and teachers has been given due importance and is reflected in this edition.

    He integrates extensive research with abundant direct clinical experience.Companion volume to successful text 'The Foundations of Chinese Medicine' Well-known and highly respected author Practical application of theory - makes text relevant to Western practitioners and students Covers 34 common diseases Includes in each case: aetiology, pathology, differentiation and treatment, and prognosis

    Respected physician, loving husband, devoted father, and trusted friend. Grant was a straight-laced kid who grew up to be a clean-living adult. No drinking, no smoking, and certainly no drugs. It took everyone by surprise, most of all himself, when he became addicted to narcotics in his 30s. His story hit local press when he was found guilty of professional misconduct related to his addition, including over-prescribing painkillers to patients so he could buy them back--an infraction that caused his physician license to be suspended.Matheson's memoir is a gritty account of his narcotic addiction and all that it cost him: various relationships, his career, and almost his life. The Golden Boy takes the reader from the very first day of Matheson's drug addiction to that moment when he decided to rebuild his life through rehab and recovery.

    Updated to reflect the latest research in the field, and enhanced with more than 1,000 illustrations, most in full-color, the 12th Edition is the most comprehensive and modern approach to understanding medical histology available anywhere.Features: NEW full-color micrographs that comprise a complete atlas of tissue sections highlight the important features of every tissue and organ in the human body. New full-color, easy-to-understand drawings provide just the right level of detail necessary to clarify the text and make learning easier A valuable introductory chapter on laboratory methods used for the study of tissues, including the most important types of microscopy A logical organization that features chapters focusing on the cytoplasmic and nuclear compartment of the cell, the four basic tissues that form the organs, and each organ system Expanded legends that accompany each figure emphasize important points and eliminate the need to jump from image to text Medical applications explain the clinical relevance of each topic Complete coverage of every tissue of the body CD-ROM with all the images from the textVisit www.LangeTextbooks.com to access valuable resources and study aids

    The book has undergone three editions, several reprints, and revised reprints in a span of 13 years. There are many biochemistry textbooks in the market. Some of them are purely basic while others are applied, and there are very few books which cover both these aspects together. For this reason, the students learning biochemistry in their undergraduate courses have to depend on multiple books to acquire a sound knowledge of the subject. This book, ‘Biochemistry’ is unique with a simultaneous and equal emphasis on basic and applied aspects of biochemistry. This textbook offers an integration of medical and pure sciences, comprehensively written to meet the curriculum requirements of undergraduate courses in medical, dental, pharmacy, life-sciences and other categories (agriculture, veterinary, etc.). This book is designed to develop in students a sustained interest and enthusiasm to learn and develop the concepts in biochemistry in a logical and stepwise manner. It incorporates a variety of pedagogic aids, besides colour illustrations to help the students understand the subject quickly and to the maximum. The summary and biomedical/clinical concepts are intended for a rapid absorption and assimilation of the facts and concepts in biochemistry. The self-assessment exercises will stimulate the students to think rather than merely learn the subject. In addition, these exercises (essays, short notes, fill in the blanks, multiple choice questions) set at different difficulty levels, will cater to the needs of all the categories of learners.New to This Edition The book offers an integration of medical and pure sciences, and is comprehensively written, revised and updated to meet the curriculum requirements of Medical, Pharmacy, Dental, Veterinary, Biotechnology, Agricultural Sciences, Life Sciences, and others studying Biochemistry as one of the subjects. It is the first text book on Biochemistry in English with multi-colour illustrations by an author from Asia. The use of multicolours is for a clearer understanding of the complicated biochemical reactions. It is written in a lucid style with the subject being presented as an engaging story growing from elementary information to the most recent advances, and with theoretical discussions being supplemented with illustrations, flowcharts, and tables for easy understanding of Biochemistry. It has each chapter beginning with a four-line verse followed by the text, biomedical concepts, a summary, and self-assessment exercises. The lively illustrations and text with appropriate headings and sub-headings in bold type faces facilitate reading path clarity and quick recall. It provides the most recent and essential information on Molecular Biology and Biotechnology, Diabetes, Cancer, Free Radicals, Free radicals and Antioxidants, Prostaglandins, etc. It describes a wide variety of case studies and biochemical correlations and several newer biomedical aspects- Metabolic syndrome, Therapeutic diets, Atkins diet, Trans fatty acids, Epigenetics, Nutrigenomics, Recombinant ribozymes, Membrane transport disorders, Pleural fluid etc. It contains the basics (Bioorganic and Biophysical Chemistry, Tools of Biochemistry, Immunology, and Genetics) for beginners to learn easily Biochemistry, origins of biochemical words, confusables in Biochemistry, principles of Practical Biochemistry, and Clinical Biochemistry Laboratory.

    Fascinating... may presage a paradigm shift in medicine." --Kirkus Reviews (starred review)Teeming with information and big ideas... Outstanding."--Booklist (starred review) The origin of asthma, autism, Alzheimer's, allergies, cancer, heart disease, obesity, and even some kinds of depression is now clear. Award-winning researcher on the microbiome, professor Rodney Dietert presents a new paradigm in human biology that has emerged in the midst of the ongoing global epidemic of noncommunicable diseases.The Human Superorganism makes a sweeping, paradigm-shifting argument. It demolishes two fundamental beliefs that have blinkered all medical thinking until very recently: 1) Humans are better off as pure organisms free of foreign microbes; and 2) the human genome is the key to future medical advances. The microorganisms that we have sought to eliminate have been there for centuries supporting our ancestors. They comprise as much as 90 percent of the cells in and on our bodies--a staggering percentage! More than a thousand species of them live inside us, on our skin, and on our very eyelashes. Yet we have now significantly reduced their power and in doing so have sparked an epidemic of noncommunicable diseases--which now account for 63 percent of all human deaths.Ultimately, this book is not just about microbes; it is about a different way to view humans. The story that Dietert tells of where the new biology comes from, how it works, and the ways in which it affects your life is fascinating, authoritative, and revolutionary. Dietert identifies foods that best serve you, the superorganism; not new fad foods but ancient foods that have made sense for millennia. He explains protective measures against unsafe chemicals and drugs. He offers an empowering self-care guide and the blueprint for a revolution in public health. We are not what we have been taught. Each of us is a superorganism. The best path to a healthy life is through recognizing that profound truth.

    Best of all, he's a gifted writer who possesses a delightfully devilish sense of humor. In these essays, which range widely but mostly focus on the relationships between biology and human behavior, hard and intricate science is handled with a deft touch that makes it accessible to the general reader. In one memorable piece, Sapolsky compares the fascination with tabloid TV to behavior he's observed among wild African baboons. "Rubber necks," notes the professor, "seem to be a common feature of the primate order." In the title essay of The Trouble with Testosterone, Sapolsky ruminates on the links, real or perceived, between that hormone and aggression.Covering such broad topics as science, politics, history, and nature, the author of Why Zebras Don't Get Ulcers writes accessible and interesting essays that explore the human struggle with moral and ethical problems in today's world. 20,000 first printing.

    In this gripping account, David Quammen takes the reader along on this astonishing quest to learn how, where from, and why these diseases emerge and asks the terrifying question: What might the next big one be?

    Michael Baden's first-person, no-holds-barred account of his distinguished career in forensic pathology. In determining the causes of tens of thousands of deaths, from those of presidents and rock stars to victims of serial killings, exotic sex rituals, mass disasters, child abuse and drug abuse, Baden has come to the unavoidable conclusion that the search for scientific truth is often sullied by the pressures of expediency. He produces dramatic evidence to demonstrate that political intrigue, influence peddling, and professional incompetence have created a national crisis in forensic medicine.

    Teresi introduces us to brain-death experts, hospice workers, undertakers, coma specialists and those who have recovered from coma, organ transplant surgeons and organ procurers, anesthesiologists who study pain in legally dead patients, doctors who have saved living patients from organ harvests, nurses who care for beating-heart cadavers, ICU doctors who feel subtly pressured to declare patients dead rather than save them, and many others. Much of what they have to say is shocking. Teresi also provides a brief history of how death has been determined from the times of the ancient Egyptians and the Incas through the twenty-first century. And he draws on the writings and theories of celebrated scientists, doctors, and researchers—Jacques-Bénigne Winslow, Sherwin Nuland, Harvey Cushing, and Lynn Margulis, among others—to reveal how theories about dying and death have changed. With The Undead, Teresi makes us think twice about how the medical community decides when someone is dead.

    You'll soon be relating to the sense of humour that moves an ambulance driver to respond to his friend and fellow paramedic's predicament on a hot summer's day, as a powerful smell engulfs the saloon of the vehicle. What would you do? Open the cab windows and the hatch through to the saloon to provide some extra ventilation? Of course not! You switch the heating on, causing the already intolerable pong to become even more unbearable, making for a bangin' mess room tale on your later return! Wonderfully illustrated with cartoons depicting each scene, it's an eye-watering insight into the Lighter Side of working on the Dark Side, straight from the mess rooms of ambulance stations up and down the UK. There's also a heartening reminder of the power of a flamin’ good belly laugh and its analgesic effect even in situations of severe pain. This is a book that laughs in the face of extreme emotion and stress. Outrageous? Perhaps. Distasteful? Probably. Humorous? Absolutely!

    Among the most compelling and perplexing of these symptoms are the strange visual hallucinations and distortions of space, time, and body image which migraineurs sometimes experience. Portrayals of these uncanny states have found their way into many works of art, from the heavenly visions of Hildegard von Bingen to Alice in Wonderland. Dr. Oliver Sacks argues that migraine cannot be understood simply as an illness, but must be viewed as a complex condition with a unique role to play in each individual's life.

    They always keep a bag packed. They seldom have more than twenty-four hours' notice before they are dispatched. The phone calls that tell them to head to the airport, sometimes in the middle of the night, may give them no more information than the country they are traveling to and the epidemic they will tackle when they get there.The universal human instinct is to run from an outbreak of disease. These doctors run toward it.They are the disease detective corps of the U.S. Centers for Disease Control and Prevention (CDC), the federal agency that tracks and tries to prevent disease outbreaks and bioterrorist attacks around the world. They are formally called the Epidemic Intelligence Service (EIS) -- a group founded more than fifty years ago out of fear that the Korean War might bring the use of biological weapons -- and, like intelligence operatives in the traditional sense, they perform their work largely in anonymity. They are not household names, but over the years they were first to confront the outbreaks that became known as hantavirus, Ebola virus, and AIDS. Now they hunt down the deadly threats that dominate our headlines: West Nile virus, anthrax, and SARS.In this riveting narrative, Maryn McKenna -- the only journalist ever given full access to the EIS in its fifty-three-year history -- follows the first class of disease detectives to come to the CDC after September 11, the first to confront not just naturally occurring outbreaks but the man-made threat of bioterrorism. They are talented researchers -- many with young families -- who trade two years of low pay and extremely long hours for the chance to be part of the group that has helped eradicate smallpox, push back polio, and solve the first major outbreaks of Legionnaires' disease, toxic shock syndrome, and "E. coli" O157.Urgent, exhilarating, and compelling, "Beating Back the Devil" goes with the EIS as they try to stop epidemics -- before the epidemics stop us.

    But if it is so bad for us, why is it ubiquitous? In Useful Delusions, Shankar Vedantam and Bill Mesler argue that, paradoxically, self-deception can also play a vital role in our success and well-being.The lies we tell ourselves sustain our daily interactions with friends, lovers, and coworkers. They can explain why some people live longer than others, why some couples remain in love and others don’t, why some nations hold together while others splinter.Filled with powerful personal stories and drawing on new insights in psychology, neuroscience, and philosophy, Useful Delusions offers a fascinating tour of what it really means to be human.