After World War II, Don's work with the Air Force brought them to Colorado, where their twelve children perfectly spanned the baby boom: the oldest born in 1945, the youngest in 1965. In those years, there was an established script for a family like the Galvins—aspiration, hard work, upward mobility, domestic harmony—and they worked hard to play their parts. But behind the scenes was a different story: psychological breakdown, sudden shocking violence, hidden abuse. By the mid-1970s, six of the ten Galvin boys, one after another, were diagnosed as schizophrenic. How could all this happen to one family?What took place inside the house on Hidden Valley Road was so extraordinary that the Galvins became one of the first families to be studied by the National Institute of Mental Health. Their story offers a shadow history of the science of schizophrenia, from the era of institutionalization, lobotomy, and the schizophrenogenic mother to the search for genetic markers for the disease, always amid profound disagreements about the nature of the illness itself. And unbeknownst to the Galvins, samples of their DNA informed decades of genetic research that continues today, offering paths to treatment, prediction, and even eradication of the disease for future generations.With clarity and compassion, bestselling and award-winning author Robert Kolker uncovers one family's unforgettable legacy of suffering, love, and hope.

    We know, for example, that there are a few core truths to science of happiness. We know that being kind and altruistic makes us happy, that turning off devices, talking to people, forging relationships, living with meaning and delving into the concerns of others offer our best chance at achieving happiness. But how do we retain happiness? It often slips out of our hands as quickly as we find it. So, when we are exposed to, or learn, good things, how do we continue to burn with them?And more than that, when our world goes dark, when we're overwhelmed by illness or heartbreak, loss or pain, how do we survive, stay alive or even bloom? In the muck and grit of a daily existence full of disappointments and a disturbing lack of control over many of the things that matter most - finite relationships, fragile health, fraying economies, a planet in peril - how do we find, nurture and carry our own inner, living light - a light to ward off the darkness?Absorbing, achingly beautiful, inspiring and deeply moving, Julia Baird has written exactly the book we need for these times.

    Now, a second thrilling tale of filial sleuthery, this time about her mother: voracious reader, music lover, passionate amateur actor. Also a woman, unhappily married to a closeted gay man, whose artistic aspirations simmered under the surface of Bechdel's childhood . . . and who stopped touching or kissing her daughter good night, forever, when she was seven. Poignantly, hilariously, Bechdel embarks on a quest for answers concerning the mother-daughter gulf. It's a richly layered search that leads readers from the fascinating life and work of the iconic twentieth-century psychoanalyst Donald Winnicott, to one explosively illuminating Dr. Seuss illustration, to Bechdel’s own (serially monogamous) adult love life. And, finally, back to Mother—to a truce, fragile and real-time, that will move and astonish all adult children of gifted mothers.

    By demystifying the fantasies surrounding cancer, Sontag shows cancer for what it is - just a disease. Cancer, she argues, is not a curse, not a punishment, certainly not an embarrassment and, it is highly curable, if good treatment is followed. Almost a decade later, with the outbreak of a new, stigmatized disease replete with mystifications and punitive metaphors, Sontag wrote a sequel to Illness as Metaphor, extending the argument of the earlier book to the AIDS pandemic.These two essays now published together, Illness as Metaphor and AIDS and Its Metaphors, have been translated into many languages and continue to have an enormous influence on the thinking of medical professionals and, above all, on the lives of many thousands of patients and caregivers.

    Running steadily through the book is Vivian Gornick's exchange of more than twenty years with Leonard, a gay man who is sophisticated about his own unhappiness, whose friendship has "shed more light on the mysterious nature of ordinary human relations than has any other intimacy" she has known. The exchange between Gornick and Leonard acts as a Greek chorus to the main action of the narrator's continual engagement on the street with grocers, derelicts, and doormen; people on the bus, cross-dressers on the corner, and acquaintances by the handful. In Leonard she sees herself reflected plain; out on the street she makes sense of what she sees.Written as a narrative collage that includes meditative pieces on the making of a modern feminist, the role of the flaneur in urban literature, and the evolution of friendship over the past two centuries, The Odd Woman and the City beautifully bookends Gornick's acclaimed Fierce Attachments, in which we first encountered her rich relationship with the ultimate metropolis.

    It begins with Sally’s visionary crack-up on the streets of Greenwich Village, and continues, among other places, in the out-of-time world of a Manhattan psychiatric ward during the city’s most sweltering months. “I feel like I’m traveling and traveling with nowhere to go back to,” Sally says in a burst of lucidity while hurtling away toward some place her father could not dream of or imagine. Hurry Down Sunshine is the chronicle of that journey, and its effect on Sally and those closest to her–her brother and grandmother, her mother and stepmother, and, not least of all, the author himself. Among Greenberg’s unforgettable gallery of characters are an unconventional psychiatrist, an Orthodox Jewish patient, a manic Classics professor, a movie producer, and a landlord with literary dreams. Unsentimental, nuanced, and deeply humane, Hurry Down Sunshine holds the reader in a mesmerizing state of suspension between the mundane and the transcendent.

    In his madness, the world was revealed to him as an enormous architecture of nerves, dominated by a predatory God. It became clear to Schreber that his personal crisis was implicated in what he called a "crisis in God's realm," one that had transformed the rest of humanity into a race of fantasms. There was only one remedy; as his doctor noted: Schreber "considered himself chosen to redeem the world, and to restore to it the lost state of Blessedness. This, however, he could only do by first being transformed from a man into a woman...."

    In this stunningly unusual prose debut, Doireann Ni Ghriofa sculpts essay and autofiction to explore inner life and the deep connection felt between two writers centuries apart. In the 1700s, an Irish noblewoman, on discovering her husband has been murdered, drinks handfuls of his blood and composes an extraordinary poem. In the present day, a young mother narrowly avoids tragedy. On encountering the poem, she becomes obsessed with its parallels with her own life, and sets out to track down the rest of the story. A devastating and timeless tale about one woman freeing her voice by reaching into the past and finding another's.

    Elegy for Iris is a story about the ephemeral beauty of youth and the sobering reality of what it means to grow old, but its ultimate power is that Bayley discovers great hope and joy in his celebration of Iris's life and their love. In its grasp of life's frailty and its portrayal of one of the great literary romances of this century, Elegy for Iris is a mesmerizing work of art that will be read for generations.

    Includes special bonus material!Sharing never-before-heard stories ranging from their struggles with depression, eating disorders, and addiction, Karen and Georgia irreverently recount their biggest mistakes and deepest fears, reflecting on the formative life events that shaped them into two of the most followed voices in the nation.In Stay Sexy & Don’t Get Murdered, Karen and Georgia focus on the importance of self-advocating and valuing personal safety over being ‘nice’ or ‘helpful.’ They delve into their own pasts, true crime stories, and beyond to discuss meaningful cultural and societal issues with fierce empathy and unapologetic frankness.

    She was a poor Southern tobacco farmer who worked the same land as her enslaved ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine. The first “immortal” human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they’d weigh more than 50 million metric tons—as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions.Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.Now Rebecca Skloot takes us on an extraordinary journey, from the “colored” ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta’s small, dying hometown of Clover, Virginia — a land of wooden quarters for enslaved people, faith healings, and voodoo — to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells.Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family — past and present — is inextricably connected to the history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of.Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah, who was devastated to learn about her mother’s cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn’t her children afford health insurance?Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.

    That is what is strange—that friends, even passionate love,are not my real life, unless there is time alone in which to explore what is happening or what has happened." In this journal, she says, "I hope to break through into the rough, rocky depths,to the matrix itself. There is violence there and anger never resolved. My need to be alone is balanced against my fear of what will happen when suddenly I enter the huge empty silence if I cannot find support there."In this book, we are closer to the marrow than ever before in May Sarton's writing.

    Mara Altman's volatile and apprehensive relationship with her body has led her to wonder about a lot of stuff over the years. Like, who decided that women shouldn't have body hair? And how sweaty is too sweaty? Also, why is breast cleavage sexy but camel toe revolting? Isn't it all just cleavage? These questions and others like them have led to the comforting and sometimes smelly revelations that constitute Gross Anatomy, an essay collection about what it's like to operate the bags of meat we call our bodies.Divided into two sections, "The Top Half" and "The Bottom Half," with cartoons scattered throughout, Altman's book takes the reader on a wild and relatable journey from head to toe—as she attempts to strike up a peace accord with our grody bits.With a combination of personal anecdotes and fascinating research, Gross Anatomy holds up a magnifying glass to our beliefs, practices, biases, and body parts and shows us the naked truth: that there is greatness in our grossness.

    Once married, however, she acquired a persistent pain that led to destructive drugs and patronizing psychiatry, ending in an ineffective but irrevocable surgery. There would be no children; in herself she found instead one novel, and then another.

    A neurologist's insightful and compassionate look into the misunderstood world of psychosomatic disorders, told through individual case histories