For most of that time, she didn't know why. All of her trips to the ER and her daily anguish, pain, and lethargy only ever resulted in one question: How could any one person be this sick? Several drug addictions, three major hospitalizations, and over $100,000 later, she finally had a diagnosis: late-stage Lyme disease. Sick is Khakpour's arduous, emotional journey—as a woman, a writer, and a lifelong sufferer of undiagnosed health problems—through the chronic illness that perpetually left her a victim of anxiety, living a life stymied by an unknown condition.Divided by settings, Khakpour guides the reader through her illness by way of the locations that changed her course—New York, LA, New Mexico, and Germany—as she meditates on both the physical and psychological impacts of uncertainty, and the eventual challenge of accepting the diagnosis she had searched for over the course of her adult life. With candor and grace, she examines her subsequent struggles with mental illness, her addiction to the benzodiazepines prescribed by her psychiatrists, and her ever-deteriorating physical health. A story about survival, pain, and transformation, Sick is a candid, illuminating narrative of hope and uncertainty, boldly examining the deep impact of illness on one woman's life.

    She was a poor Southern tobacco farmer who worked the same land as her enslaved ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine. The first “immortal” human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they’d weigh more than 50 million metric tons—as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions.Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.Now Rebecca Skloot takes us on an extraordinary journey, from the “colored” ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta’s small, dying hometown of Clover, Virginia — a land of wooden quarters for enslaved people, faith healings, and voodoo — to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells.Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family — past and present — is inextricably connected to the history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of.Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah, who was devastated to learn about her mother’s cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn’t her children afford health insurance?Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.

    In this extraordinary memoir, she opens a window into the experience of wordlessness—the language paralysis called aphasia. In narrating the recovery of her husband, Paul West, from a stroke that reduced his vast vocabulary to a single syllable, she evokes the joy and mystery of the brain’s ability to find and connect words. Deeply rewarding to readers of all kinds, Ackerman has given us a literary love story, accessible insight into the science and medicine of brain injury,and invaluable spiritual sustenance in the face of life’s myriad physical sufferings.

    Its greatest detriment to the world has been its unfettered desire to play with and alter them: science for science's sake, as if it offered the only path to knowledge.According to Lehrer, when it comes to the human brain, the world of art unraveled such mysteries long before the neuroscientists: "This book is about artists who anticipated the discoveries of science who discovered truths about the human mind that science is only now discovering." 'Proust Was a Neuroscientist' is a dazzling inquiry into the nature of the mind and of the truths harvested by its first explorers: artists like Walt Whitman, George Eliot, Auguste Escoffier, Marcel Proust, Paul Cozanne, Igor Stravinsky, Gertrude Stein, and Virginia Woolf. What they understood intuitively and expressed through their respective art forms -- the fallibility of memory, the malleability of the brain, the subtleties of vision, and the deep structure of language -- science has only now begun to measure and confirm. Blending biography, criticism, and science writing, Lehrer offers a lucid examination of eight artistic thinkers who lit the path toward a greater understanding of the human mind and a deeper appreciation of the ineffable mystery of life.

    Randy Christensen. Trained as a pediatrician, he works not in a typical hospital setting but, rather, in a 38-foot Winnebago that has been refitted as a doctor’s office on wheels. His patients are the city’s homeless adolescents and children. In the shadow of one affluent American city, Dr. Christensen has dedicated his life to caring for society's throwaway kids—the often-abused, unloved children who live on the streets without access to proper health care, all the while fending off constant threats from thugs, gangs, pimps, and other predators. With the Winnebago as his moveable medical center, Christensen and his team travel around the outskirts of Phoenix, attending to the children and teens who need him most. With tenderness and humor, Dr. Christensen chronicles everything from the struggles of the van’s early beginnings, to the support system it became for the kids, and the ultimate recognition it has achieved over the years. Along with his immense professional challenges, he also describes the trials and joys he faces while raising a growing family with his wife Amy. By turns poignant, heartbreaking, and charming, Dr. Christensen's story is a gripping and rich memoir of his work and family, one of those rare books that stays with you long after you’ve turned the last page.

    It's what you have if you're a politician and you've strayed from your wife, and it's why five times as many Americans undergo plastic surgery and cosmetic procedures today than did just ten years ago. It's the value that parents teach their children with song lyrics like "I am special. Look at me," the skill teenagers and young adults obsessively hone on Facebook and MySpace, and the reason high school students physically beat classmates and then broadcast their violence on YouTube for all to see. It's the message preached by prosperity gospel and the vacuous ethos spread by celebrity newsmakers. And it's what's making people depressed, lonely, and buried under piles of debt.Jean M. Twenge's influential and controversial first book, Generation Me, generated a national debate with its trenchant depiction of the challenges twenty- and thirtysomethings face emotionally and professionally in today's world -- and the fallout these issues create for older generations as well as employers. Now, Dr. Twenge is on to a new incendiary topic that has repercussions for every age-group and class: the pernicious spread of narcissism in today's culture and its catastrophic effects. Dr. Twenge joins forces with W. Keith Campbell, Ph.D., a nationally recognized expert on narcissism, for The Narcissism Epidemic, their eye-opening exposition of the alarming rise of narcissism -- and they show how to stop it.Every day, you encounter the real costs of narcissism: in your relationships and family, in the workplace and the economy at large, in schools that fail to teach necessary skills, in culture, and in politics. Even the world economy has been damaged by risky, unrealistic overconfidence. Filled with arresting anecdotes that illustrate the hold narcissism has on us today -- from people hiring fake paparazzi in order to experience feeling famous to college students who won't leave a professor's office until their B+ becomes an A -- The Narcissism Epidemic is at once a riveting window into the consequences of narcissism, a probing analysis of the culture at large, and a prescription to combat the widespread problems caused by narcissism. As a society, we have a chance to slow the epidemic of narcissism once we learn to identify it, minimize the forces that sustain and transmit it, and treat it where we find it. Drawing on their own extensive research as well as decades of other experts' studies, Drs. Twenge and Campbell show us how.

    By allowing women to control their fertility, the birth control pill has revolutionized women's lives. Women are going to college, graduating, and entering the workforce in greater numbers than ever before, and there's good reason to believe that the birth control pill has a lot to do with this. But there's a lot more to the pill than meets the eye.Although women go on the pill for a small handful of targeted effects (pregnancy prevention and clearer skin, yay!), sex hormones can't work that way. Sex hormones impact the activities of billions of cells in the body at once, many of which are in the brain. There, they play a role in influencing attraction, sexual motivation, stress, hunger, eating patterns, emotion regulation, friendships, aggression, mood, learning, and more. This means that being on the birth control pill makes women a different version of themselves than when they are off of it. And this is a big deal. For instance, women on the pill have a dampened cortisol spike in response to stress. While this might sound great (no stress!), it can have negative implications for learning, memory, and mood. Additionally, because the pill influences who women are attracted to, being on the pill may inadvertently influence who women choose as partners, which can have important implications for their relationships once they go off it. Sometimes these changes are for the better . . . but other times, they're for the worse. By changing what women's brains do, the pill also has the ability to have cascading effects on everything and everyone that a woman encounters. This means that the reach of the pill extends far beyond women's own bodies, having a major impact on society and the world.This paradigm-shattering book provides an even-handed, science-based understanding of who women are, both on and off the pill. It will change the way that women think about their hormones and how they view themselves. It also serves as a rallying cry for women to demand more information from science about how their bodies and brains work and to advocate for better research. This book will help women make more informed decisions about their health, whether they're on the pill or off of it.

    Now the man who coined the phrase "serial killer" and advised Thomas Harris on The Silence of the Lambs shows how is able to track down some of today's most brutal murderers.Just as it happened in The Silence of the Lambs, Ressler used the evidence at a crime scene to put together a psychological profile of the killers. From the victims they choose, to the way they kill, to the often grotesque souvenirs they take with them--Ressler unlocks the identities of these vicious killers of the police to capture.And with his discovery that serial killers share certain violent behaviors, Ressler's gone behind prison walls to hear the bizarre first-hand stories countless convicted murderers. Getting inside the mind of a killer to understand how and why he kills, is one of the FBI's most effective ways of helping police bring in killers who are still at large.Join Ressler as he takes you on the hunt for toady's most dangerous psychopaths. It is a terrifying journey you will not forget.

    It killed more people in twenty-four months than AIDS killed in twenty-four years, more in a year than the Black Death killed in a century. But this was not the Middle Ages, and 1918 marked the first collision of science and epidemic disease. Magisterial in its breadth of perspective and depth of research and now revised to reflect the growing danger of the avian flu, The Great Influenza is ultimately a tale of triumph amid tragedy, which provides us with a precise and sobering model as we confront the epidemics looming on our own horizon. John M. Barry has written a new afterword for this edition that brings us up to speed on the terrible threat of the avian flu and suggest ways in which we might head off another flu pandemic.

    Kennedy, the former congressman and youngest child of Senator Ted Kennedy, details his personal and political battle with mental illness and addiction, exploring mental health care's history in the country alongside his and every family's private struggles.On May 5, 2006, the New York Times ran two stories, “Patrick Kennedy Crashes Car into Capitol Barrier” and then, several hours later, “Patrick Kennedy Says He'll Seek Help for Addiction.” It was the first time that the popular Rhode Island congressman had publicly disclosed his addiction to prescription painkillers, the true extent of his struggle with bipolar disorder and his plan to immediately seek treatment. That could have been the end of his career, but instead it was the beginning. Since then, Kennedy has become the nation’s leading advocate for mental health and substance abuse care, research and policy both in and out of Congress. And ever since passing the landmark Mental Health Parity and Addiction Equity Act--and after the death of his father, leaving Congress--he has been changing the dialogue that surrounds all brain diseases.A Common Struggle weaves together Kennedy's private and professional narratives, echoing Kennedy's philosophy that for him, the personal is political and the political personal. Focusing on the years from his 'coming out' about suffering from bipolar disorder and addiction to the present day, the book examines Kennedy's journey toward recovery and reflects on Americans' propensity to treat mental illnesses as "family secrets."Beyond his own story, though, Kennedy creates a roadmap for equality in the mental health community, and outlines a bold plan for the future of mental health policy. Written with award-winning healthcare journalist and best-selling author Stephen Fried, A Common Struggle is both a cry for empathy and a call to action.

    The outcome was unexpected—when Henry awoke, he could no longer form new memories, and for the rest of his life would be trapped in the moment. But Henry’s tragedy would prove a gift to humanity. As renowned neuroscientist Suzanne Corkin explains in Permanent Present Tense, she and her colleagues brought to light the sharp contrast between Henry’s crippling memory impairment and his preserved intellect. This new insight that the capacity for remembering is housed in a specific brain area revolutionized the science of memory. The case of Henry—known only by his initials H. M. until his death in 2008—stands as one of the most consequential and widely referenced in the spiraling field of neuroscience. Corkin and her collaborators worked closely with Henry for nearly fifty years, and in Permanent Present Tense she tells the incredible story of the life and legacy of this intelligent, quiet, and remarkably good-humored man. Henry never remembered Corkin from one meeting to the next and had only a dim conception of the importance of the work they were doing together, yet he was consistently happy to see her and always willing to participate in her research. His case afforded untold advances in the study of memory, including the discovery that even profound amnesia spares some kinds of learning, and that different memory processes are localized to separate circuits in the human brain. Henry taught us that learning can occur without conscious awareness, that short-term and long-term memory are distinct capacities, and that the effects of aging-related disease are detectable in an already damaged brain.Undergirded by rich details about the functions of the human brain, Permanent Present Tense pulls back the curtain on the man whose misfortune propelled a half-century of exciting research. With great clarity, sensitivity, and grace, Corkin brings readers to the cutting edge of neuroscience in this deeply felt elegy for her patient and friend.

    But work takes a strange turn when she is promoted onto the Pfizer account and suddenly finds herself on the other side of the curtain, developing ads for an anti-depressant drug. Overwhelmed by her professional life and the self-scrutiny it inspires, her mania takes hold. She quits her job to become an artist, only to be hospitalized by her parents against her will. Over the course of her two weeks in the ward, she tries to find a path out of the hospital and this cycle of treatment. One where she can live the life she wants, finding freedom and autonomy, without sacrificing her dreams in order to stay well.

    But we should--even those of us who take care of our business in pristine, sanitary conditions. For it's not only in developing countries that human waste is a major public health threat: population growth is taxing even the most advanced sewage systems, and the disease spread by waste kills more people worldwide every year than any other single cause of death. Even in America, 1.95 million people have no access to an indoor toilet. Yet the subject remains unmentionable."The Big Necessity "takes aim at the taboo, revealing everything that matters about how people do--and don't--deal with their own waste. Moving from the deep underground sewers of Paris, London, and New York--an infrastructure disaster waiting to happen--to an Indian slum where ten toilets are shared by 60,000 people, Rose George stops along the way to explore the potential saviors: China's five million biogas digesters, which produce energy from waste; the heroes of third world sanitation movements; the inventor of the humble Car Loo; and the U.S. Army's personal lasers used by soldiers to zap their feces in the field.With razor-sharp wit and crusading urgency, mixing levity with gravity, Rose George has turned the subject we like to avoid into a cause with the most serious of consequences.

    The COO fired back with a dismissive and insulting email, to which Tyler replied: "Consider this my two weeks’ notice."From there, his life spun out of control at the hand of Elizabeth, her team of high-powered lawyers, and the patriarch of Tyler’s own family, George Shultz—one of America’s most prominent statesmen, who sat among the top of the Theranos Board of Directors. And yet, Tyler forged on. To protect his own conscience, the honor and reputation of his grandfather, and the health of patients worldwide.Thicker than Water is Tyler’s as-told-to story—a harrowing and heartbreaking roller coaster of biomedical drama, family intrigue, and redemption—that will ultimately make you feel as though you are at a dinner party, seated next to a brilliant friend with one hell of a story.

    When the Close sisters were very young, their parents joined a cult called the MRA, or Moral Rearmament. The family was suddenly uprooted to a cult school in Switzerland and, ultimately, to the Belgian Congo where their father became a surgeon in the war-ravaged republic, and ultimately the personal physician to President Mobutu. Shortly after the girls returned to the US for boarding school, Jessie first started to exhibit symptoms of severe bipolar disorder (she would later learn that this ran in the family, a well-kept secret). Jessie embarked on a series of destructive marriages as the condition worsened. Glenn was always by her side throughout. Jessie's mental illness was passed on to her son, Calen. It wasn't until Calen entered McLean's psychiatric hospital that Jessie herself was diagnosed. Fifteen years and twelve years of sobriety later, Jessie is a stable and productive member of society. Glenn continues to be the major support in Jessie's life.In Resilience, the sisters share their story of triumphing over Jessie's illness. The book is written in Jessie's voice with running commentary and an epilogue written by Glenn.