But treatment for it has not changed much in the last three decades. In the world of psychiatry, time has apparently stood still... until now. In this game-changing book, University of Cambridge Professor Edward Bullmore reveals the breakthrough new science on the link between depression and inflammation of the body and brain. He explains how and why we now know that mental disorders can have their root cause in the immune system, and outlines a future revolution in which treatments could be specifically targeted to break the vicious cycle of stress, inflammation and depression. The Inflamed Mind goes far beyond the clinic and the lab, representing a whole new way of looking at how mind, brain and body all work together in a sometimes misguided effort to help us survive in a hostile world. It offers insights into the story of Western medicine, how we have got it wrong as well as right in the past, and how we could start getting to grips with depression and other mental disorders much more effectively in the future.

    From her first frightening night at a shelter, Janice knew she was in over her head. She was beaten up, shaken down, and nearly stabbed by a pregnant girl. But it was still better than living at home. As Janice slipped further into street life, she nevertheless attended high school, harbored crushes, and even played the lead in the spring musical. She also roamed the streets, clubs, bars, and parks of New York City with her two best girlfriends, on the prowl for hard drugs and boys on skateboards. Together they scored coke at Danceteria, smoked angel dust in East Village squats, commiserated over their crazy mothers, and slept with one another’s boyfriends on a regular basis. A wry, mesmerizing portrait of being underprivileged, underage, and underdressed in 1980s New York City, Girlbomb provides an unflinching look at street life, survival sex, female friendships, and first loves.“A fast and engrossing read in the spirit of Girl, Interrupted.”–Entertainment Weekly“Gripping . . . a wry, compelling memoir of what it means to stand up for yourself, especially when no one else will.”–Bust“How satisfying to watch Erlbaum survive adolescence and produce a smart, engaging book.”–The New York Times Book Review“Erlbaum’s survival is hard-won, the journey rendered with page-turning intensity.”–New York Post“A fast and engrossing read in the spirit of Girl, Interrupted.”–Entertainment Weekly“Gritty . . . perversely riveting. You want her to survive.”–The Washington Post Book World

    She also lectures widely on autism—because Temple Grandin is autistic, a woman who thinks, feels, and experiences the world in ways that are incomprehensible to the rest of us. In this unprecedented book, Grandin delivers a report from the country of autism. Writing from the dual perspectives of a scientist and an autistic person, she tells us how that country is experienced by its inhabitants and how she managed to breach its boundaries to function in the outside world. What emerges in Thinking in Pictures is the document of an extraordinary human being, one who, in gracefully and lucidly bridging the gulf between her condition and our own, sheds light on the riddle of our common identity.

    While studying brain scans of several family members, he discovered that one perfectly matched a pattern he d found in the brains of serial killers. This meant one of two things: Either his family s scans had been mixed up with those of felons or someone in his family was a psychopath.Even more disturbing: The scan in question was his own.This is Fallon s account of coming to grips with this discovery and its implications. How could he, a happy family man who had never been prone to violence, be a psychopath? How much did his biology influence his behavior?Fallon shares his journey to answer these questions and the discoveries that ultimately led to his conclusion: Despite everything science can teach, humans are even more complex than we can imagine."

    He’s a sociopath. And your boss, teacher, and colleague? They may be sociopaths too.We are accustomed to think of sociopaths as violent criminals, but in The Sociopath Next Door, Harvard psychologist Martha Stout reveals that a shocking 4 percent of ordinary people—one in twenty-five—has an often undetected mental disorder, the chief symptom of which is that that person possesses no conscience. He or she has no ability whatsoever to feel shame, guilt, or remorse. One in twenty-five everyday Americans, therefore, is secretly a sociopath. They could be your colleague, your neighbor, even family. And they can do literally anything at all and feel absolutely no guilt. How do we recognize the remorseless? One of their chief characteristics is a kind of glow or charisma that makes sociopaths more charming or interesting than the other people around them. They’re more spontaneous, more intense, more complex, or even sexier than everyone else, making them tricky to identify and leaving us easily seduced. Fundamentally, sociopaths are different because they cannot love. Sociopaths learn early on to show sham emotion, but underneath they are indifferent to others’ suffering. They live to dominate and thrill to win. The fact is, we all almost certainly know at least one or more sociopaths already. Part of the urgency in reading The Sociopath Next Door is the moment when we suddenly recognize that someone we know—someone we worked for, or were involved with, or voted for—is a sociopath. But what do we do with that knowledge? To arm us against the sociopath, Dr. Stout teaches us to question authority, suspect flattery, and beware the pity play. Above all, she writes, when a sociopath is beckoning, do not join the game. It is the ruthless versus the rest of us, and The Sociopath Next Door will show you how to recognize and defeat the devil you know.

    But in Catching Fire, renowned primatologist Richard Wrangham presents a startling alternative: our evolutionary success is the result of cooking. In a groundbreaking theory of our origins, Wrangham shows that the shift from raw to cooked foods was the key factor in human evolution. when our ancestors adapted to using fire, humanity began.Once our hominid ancestors began cooking their food, the human digestive tract shrank and the brain grew. Time once spent chewing tough raw food could be used instead to hunt and to tend camp. Cooking became the basis for pair bonding and marriage, created the household, and even led to a sexual division of labor.Tracing the contemporary implications of our ancestors' diets, Catching Fire sheds new light on how we came to be the social, intelligent, and sexual species we are today. A pathbreaking new theory of human evolution, Catching Fire will provoke controversy and fascinate anyone interested in our ancient origins--or in our modern eating habits.--from the dustjacket

    With more than one in every five people over the age of fourteen addicted, drug abuse has been called the most formidable health problem worldwide. If we are not victims ourselves, we all know someone struggling with the merciless compulsion to alter their experience by changing how their brain functions.Drawing on years of research--as well as personal experience as a recovered addict--researcher and professor Judy Grisel has reached a fundamental conclusion: for the addict, there will never be enough drugs. The brain's capacity to learn and adapt is seemingly infinite, allowing it to counteract any regular disruption, including that caused by drugs. What begins as a normal state punctuated by periods of being high transforms over time into a state of desperate craving that is only temporarily subdued by a fix, explaining why addicts are unable to live either with or without their drug. One by one, Grisel shows how different drugs act on the brain, the kind of experiential effects they generate, and the specific reasons why each is so hard to kick.Grisel's insights lead to a better understanding of the brain's critical contributions to addictive behavior, and will help inform a more rational, coherent, and compassionate response to the epidemic in our homes and communities.

    Yet for nearly all of its six million years of existence, human society had none of these things. While the gulf that divides us from our primitive ancestors may seem unbridgeably wide, we can glimpse much of our former lifestyle in those largely traditional societies still or recently in existence. Societies like those of the New Guinea Highlanders remind us that it was only yesterday—in evolutionary time—when everything changed and that we moderns still possess bodies and social practices often better adapted to traditional than to modern conditions.The World Until Yesterday provides a mesmerizing firsthand picture of the human past as it had been for millions of years—a past that has mostly vanished—and considers what the differences between that past and our present mean for our lives today.This is Jared Diamond’s most personal book to date, as he draws extensively from his decades of field work in the Pacific islands, as well as evidence from Inuit, Amazonian Indians, Kalahari San people, and others. Diamond doesn’t romanticize traditional societies—after all, we are shocked by some of their practices—but he finds that their solutions to universal human problems such as child rearing, elder care, dispute resolution, risk, and physical fitness have much to teach us. Provocative, enlightening, and entertaining, The World Until Yesterday is an essential and fascinating read.

    A lifelong nonbeliever, he found himself on a bizarre adventure, involving a disgraced pastor, a mysterious self-help guru, and a gaggle of brain scientists. Eventually, Harris realized that the source of his problems was the very thing he always thought was his greatest asset: the incessant, insatiable voice in his head, which had both propelled him through the ranks of a hyper-competitive business and also led him to make the profoundly stupid decisions that provoked his on-air freak-out.We all have a voice in our head. It’s what has us losing our temper unnecessarily, checking our email compulsively, eating when we’re not hungry, and fixating on the past and the future at the expense of the present. Most of us would assume we’re stuck with this voice – that there’s nothing we can do to rein it in – but Harris stumbled upon an effective way to do just that. It’s a far cry from the miracle cures peddled by the self-help swamis he met; instead, it’s something he always assumed to be either impossible or useless: meditation. After learning about research that suggests meditation can do everything from lower your blood pressure to essentially rewire your brain, Harris took a deep dive into the underreported world of CEOs, scientists, and even marines who are now using it for increased calm, focus, and happiness.10% Happier takes readers on a ride from the outer reaches of neuroscience to the inner sanctum of network news to the bizarre fringes of America’s spiritual scene, and leaves them with a takeaway that could actually change their lives.

    From A Child Called “It” to The Lost Boy, from A Man Named Dave to Help Yourself, Dave Pelzer’s inspirational books have helped countless others triumph over hardship and misfortune.  In The Privilege of Youth, he shares the missing chapter of his life: as a boy on the threshold of adulthood.  With sensitivity and insight, he recounts the relentless taunting he endured from bullies; but he also describes the thrill of making his first real friends—some of whom he still shares close relationships with today.  He writes about the simple pleasures of exploring his neighborhood, while trying to forget the hell waiting for him at home.From high school to a world beyond the four walls that were his prison for so many years, The Privilege of Youth bravely and compassionately charts this crucial turning point in Dave Pelzer’s life and will inspire a whole new generation of readers.

    Many women in America have experienced it. What’s expected of women and what it’s really like to be a woman in today’s world are two very different things—and women exhaust themselves trying to close the gap between them. How can you “love your body” when every magazine cover has ten diet tips for becoming “your best self”? How do you “lean in” at work when you’re already operating at 110 percent and aren’t recognized for it? How can you live happily and healthily in a sexist world that is constantly telling you you’re too fat, too needy, too noisy, and too selfish?Sisters Emily Nagoski, PhD, and Amelia Nagoski, DMA, are here to help end the cycle of feeling overwhelmed and exhausted. Instead of asking us to ignore the very real obstacles and societal pressures that stand between women and well-being, they explain with compassion and optimism what we’re up against—and show us how to fight back. In these pages you’ll learn• what you can do to complete the biological stress cycle—and return your body to a state of relaxation• how to manage the “monitor” in your brain that regulates the emotion of frustration• how the Bikini Industrial Complex makes it difficult for women to love their bodies—and how to defend yourself against it• why rest, human connection, and befriending your inner critic are keys to recovering and preventing burnoutWith the help of eye-opening science, prescriptive advice, and helpful worksheets and exercises, all women will find something transformative in these pages—and will be empowered to create positive change. Emily and Amelia aren’t here to preach the broad platitudes of expensive self-care or insist that we strive for the impossible goal of “having it all.” Instead, they tell us that we are enough, just as we are—and that wellness, true wellness, is within our reach.

    Most us have disturbed, restless nights and rely on a cocktail of caffeine and sugar to drag us through the day. Yet the hours we spend in bed shape our mood, motivation and decision-making skills - defining our performance in work, at home and keeping fit.We need a new approach to sleep. One that helps us cope with our ever more demanding days and always be our personal best.Nick Littlehales is the elite sleep coach to some of the world's leading sports stars and teams, across Premiership and international football, British Cycling and Team Sky, rugby and Olympic sports. His groundbreaking practical techniques have transformed the way athletes approach sleep, unlocking higher levels of mental and physical recovery, personal best performances and ultimately a winning mindset.Now he lays bare his strategies for us all to use. From your personal sleep characteristics and cycles, to posture and bedding, he sets out achievable ways to get the highest possible quality of sleep recovery.Read Sleep, learn from the best in sport, and kickstart a more confident, successful and happier you.

    Yet most of us don’t know how to read body language–and don’t realize how our own physical movements speak to others. Now the world’s foremost experts on the subject share their techniques for reading body language signals to achieve success in every area of life.Drawing upon more than thirty years in the field, as well as cutting-edge research from evolutionary biology, psychology, and medical technologies that demonstrate what happens in the brain, the authors examine each component of body language and give you the basic vocabulary to read attitudes and emotions through behavior. Discover:• How palms and handshakes are used to gain control• The most common gestures of liars• How the legs reveal what the mind wants to do• The most common male and female courtship gestures and signals• The secret signals of cigarettes, glasses, and makeup• The magic of smiles–including smiling advice for women• How to use nonverbal cues and signals to communicate more effectively and get the reactions you wantFilled with fascinating insights, humorous observations, and simple strategies that you can apply to any situation, this intriguing book will enrich your communication with and understanding of others–as well as yourself.

    To the right listener, they tell us all about themselves: where they came from, how they lived, how they died - and who killed them. Forensic scientists can unlock the mysteries of the past and help justice to be done using the messages left by a corpse, a crime scene or the faintest of human traces. Forensics uncovers the secrets of forensic medicine, drawing on interviews with top-level professionals, ground-breaking research and Val McDermid's own experience to lay bare the secrets of this fascinating science. And, along the way, she wonders at how maggots collected from a corpse can help determine time of death, how a DNA trace a millionth the size of a grain of salt can be used to convict a killer and how a team of young Argentine scientists led by a maverick American anthropologist uncovered the victims of a genocide.In her crime novels, Val McDermid has been solving complex crimes and confronting unimaginable evil for years. Now, she's looking at the people who do it for real, and real crime scenes. It's a journey that will take her to war zones, fire scenes and autopsy suites, and bring her into contact with extraordinary bravery and wickedness, as she traces the history of forensics from its earliest beginnings to the cutting-edge science of the modern day.

    And yet, until very recently, scientists believed our brains were fully developed from childhood on. Now, thanks to imaging technology that enables us to look inside the living human brain at all ages, we know that this isn't so. Professor Sarah-Jayne Blakemore, one of the world's leading researchers into adolescent neurology, explains precisely what is going on in the complex and fascinating brains of teenagers--namely that the brain goes on developing and changing right through adolescence--with profound implications for the adults these young people will become.Drawing from cutting-edge research, including her own, Blakemore shows:How an adolescent brain differs from those of children and adultsWhy problem-free kids can turn into challenging teensWhat drives the excessive risk-taking and all-consuming relationships common among teenagersAnd why many mental illnesses--depression, addiction, schizophrenia--present during these formative yearsBlakemore's discoveries have transformed our understanding of the teenage mind, with consequences for law, education policy and practice, and, most of all, parents.