Sapolsky's acclaimed and successful Why Zebras Don't Get Ulcers features new chapters on how stress affects sleep and addiction, as well as new insights into anxiety and personality disorder and the impact of spirituality on managing stress.As Sapolsky explains, most of us do not lie awake at night worrying about whether we have leprosy or malaria. Instead, the diseases we fear--and the ones that plague us now--are illnesses brought on by the slow accumulation of damage, such as heart disease and cancer. When we worry or experience stress, our body turns on the same physiological responses that an animal's does, but we do not resolve conflict in the same way--through fighting or fleeing. Over time, this activation of a stress response makes us sick.

    Others are sure it's the environment we experience in childhood. But could it be that many of our individual characteristics—our health, our intelligence, our temperaments—are influenced by the conditions we encountered before birth? That's the claim of an exciting and provocative field known as fetal origins. Over the past twenty years, scientists have been developing a radically new understanding of our very earliest experiences and how they exert lasting effects on us from infancy well into adulthood. Their research offers a bold new view of pregnancy as a crucial staging ground for our health, ability, and well-being throughout life.Author and journalist Annie Murphy Paul ventures into the laboratories of fetal researchers, interviews experts from around the world, and delves into the rich history of ideas about how we're shaped before birth. She discovers dramatic stories: how individuals gestated during the Nazi siege of Holland in World War II are still feeling its consequences decades later; how pregnant women who experienced the 9/11 attacks passed their trauma on to their offspring in the womb; how a lab accident led to the discovery of a common household chemical that can harm the developing fetus; how the study of a century-old flu pandemic reveals the high personal and societal costs of poor prenatal experience. Origins also brings to light astonishing scientific findings: how a single exposure to an environmental toxin may produce damage that is passed on to multiple generations; how conditions as varied as diabetes, heart disease, and mental illness may get their start in utero; why the womb is medicine's latest target for the promotion of lifelong health, from preventing cancer to reducing obesity. The fetus is not an inert being, but an active and dynamic creature, responding and adapting as it readies itself for life in the particular world it will enter. The pregnant woman is not merely a source of potential harm to her fetus, as she is so often reminded, but a source of influence on her future child that is far more powerful and positive than we ever knew. And pregnancy is not a nine-month wait for the big event of birth, but a momentous period unto itself, a cradle of individual strength and wellness and a crucible of public health and social equality.With the intimacy of a personal memoir and the sweep of a scientific revolution, Origins presents a stunning new vision of our beginnings that will change the way you think about yourself, your children, and human nature itself.

    Only a small fraction of those affected have been properly diagnosed, leaving many others to suffer in silence or pursue ill-advised conventional treatment methods that fail to address the cause of this painful condition. Tara Grant, a twenty-year sufferer of HS, has become an underground legend to her Internet community of HS victims by presenting a methodical, self-tested action plan to heal naturally. The centerpiece of her holistic approach rests on the understanding that HS is an autoimmune disorder caused by leaky gut syndrome. With a few simple dietary changes that eliminate certain “trigger” foods, you can heal your gut, restore your skin, reclaim your health, and rid yourself of HS symptoms forever. That’s it—no antibiotics, no experimental surgeries, and no more pain, suffering, or confusion.Q&A with Tara1. What was it about the subject you chose to write about in your book that made you feel so passionate about spreading the word and getting your book published? My motivation for writing this book was the overwhelming response I received from people on the Internet when I originally posted about it in March of 2012. It turns out it’s a pretty common condition, but many people (and doctors) don’t know what it is. It’s pretty standard to visit various doctors, and be told that you have “acne,” or to be subjected to butchering surgeries. There is no treatment for HS, according to the doctors. People with it suffer immensely—in fact, HS is acknowledged to be one of most painful conditions in the world. I’ve even received letters from doctors and nurses who suffer from HS, thanking me for telling them what it is that they have—and for offering them hope. The primary motivating factor for writing this book, however, was an email I received from a 12-year old girl, who said she was going to kill herself because of the pain she was in. I immediately wrote her back, but I never heard back from her. I am desperate to know that she’s okay. I don’t want anyone else to go through what I did as a teenager—I myself thought about suicide on more than one occasion. I’ve had many letters from people who say they want to kill themselves since.2. HS is hard to diagnose, and many doctors aren’t even aware of its existence. How did you get a diagnosis? I’ve had HS since I was thirteen years old, but wasn’t diagnosed until I was in my mid-30s. Up until then, I saw over forty doctors from four different countries - none of whom could tell me what was wrong with me. I eventually found the name “Hidradenitis suppurativa” in a book about PCOS (also known as polycystic ovarian syndrome, which I also had) and could finally put a name to the horrible condition I had suffered from for so long. I took that information to a dermatologist. That’s when I finally got a diagnosis—over twenty years later. At that time, I had already changed to a Primal diet and my HS was drastically better, so I declined the antibiotics and Accutane the doctor prescribed. I also refused to believe what she said: “You have to live with this for the rest of your life.” I knew, as a longtime sufferer of HS, that the doctors I had seen had no clue what they were talking about. My journey was extremely frustrating, and I went through it completely alone. Over the years, I was told I had “adult acne,” and also told that they didn’t know what was wrong with me. I was also told that I was overreacting, not keeping clean enough, and told to lose weight. Not a single doctor showed any compassion, or was willing to look into the matter further. I eventually stopped going to the doctors, and didn’t return until I had already made changes and knew I was on the right track. I knew that if I wanted answers, I had to do the research and experimentation myself. I wasn't interested in how I reacted to different drug, I was interested in healing myself naturally.  I knew that I was on the right track with diet, so I started investigating Robb Wolf’s Autoimmune Paleo Protocol, and made specific tweaks for skin conditions. Results I had seen from others (Dr. Terry Wahls, for example) who had healed themselves from crippling autoimmune conditions were the only motivation I needed. When I started treating HS like an autoimmune condition, it went into remission. There are literally thousands of cases of this happening with different autoimmune conditions all over the world. I was also able to induce flare-ups with specific experimentation. This completely checks with autoimmunity. There isn’t a cure—you will always have the predisposition for autoimmunity—but you CAN go into remission. 3. Do you have any relatives or close friends that became diagnosed after you?  There is no one else in my family with this condition. There is a mistaken belief that HS is hereditary. It is not. However, some families have more than one member affected by it. The reason for this is that HS is autoimmune. In order to get an autoimmune condition, you need to have the gene for autoimmunity. The fact that the autoimmune gene manifests as HS in more than one family member is complete coincidence. If you’re suffering from HS, you more than likely have other autoimmune conditions - and so does your family. Family trees littered with Crohn’s, rheumatoid arthritis, multiple sclerosis, restless legs syndrome, diabetes, Lupus, endometriosis, eczema, psoriasis, HS, and more—all of which are autoimmune—are very common. If you have HS, you have the autoimmune gene, which you did inherit. If your gut becomes leaky, then you will eventually develop an autoimmune condition.4. Do you have advice for anyone seeking medical help for this condition? Read my book first. The Western medical community is still under the mistaken belief that HS is caused by bacteria, hence the prescriptions for antibiotics. They will not be able to help you, and will suggest butchering surgeries and heavy hitting drugs, which often make matters worse. You can’t “cut HS out,” like you do with a cancerous tumor. When you remove an organ or tissue that is being ravaged by an autoimmune response, you open up all your other organs and tissues to attack. That’s why there’s over an 80% chance of reoccurrence of HS after surgery, and people will often start flaring-up in areas that had been clear before. Sometimes, they even develop brand new autoimmune conditions. Luckily, you actually hold the key to healing in your hands. You can heal yourself. If you can avoid infection, then you don’t need doctors—or drugs— to help you go into remission.5. What is the one thing you would stress most to anyone unable to get a copy of your book at this time? Many people with HS are on disability and don’t have a lot of disposable income, or they have been taken advantage of in the past. If this is you, go to your local library and ask them to carry the book. Then, you can borrow it for free. How much does a 1-oz jar of EmuAid cost? Turmeric capsules? Surgery? Doctor visits and prescriptions? We’ve all fallen for so much. I bet if you sat down and tallied up how much you’ve spent on Band-Aids alone for your HS over the years, $26 would be a drop in the bucket. The great thing about this book is that if you are not satisfied, you can request your money back. If you get this 300-page manual and find that there is nothing in it that is of any help, you can ask for a refund from the publisher. Try asking for a refund for EmuAid when it doesn’t work. That being said, I would challenge anyone with HS to read this book and find nothing in it that’s helpful.6. Your book is a very important first step in making the public aware of this illness. Besides the book, how do you plan to raise awareness of HS?My goal is to get on the Dr. Oz show. I figure that will give us the biggest bang for the buck. Many people have HS, but are unaware of what it’s called. They’re too embarrassed to go to the doctor about it. I would encourage all of you to write to the Dr. Oz show and ask them to feature me, and ask your local library to carry the book. The only way we’re going to raise awareness is to GO BIG.

    This latest book gives you a precise regimen for self-treatment along with extensive information on other resources now available to you.

    With more than one in every five people over the age of fourteen addicted, drug abuse has been called the most formidable health problem worldwide. If we are not victims ourselves, we all know someone struggling with the merciless compulsion to alter their experience by changing how their brain functions.Drawing on years of research--as well as personal experience as a recovered addict--researcher and professor Judy Grisel has reached a fundamental conclusion: for the addict, there will never be enough drugs. The brain's capacity to learn and adapt is seemingly infinite, allowing it to counteract any regular disruption, including that caused by drugs. What begins as a normal state punctuated by periods of being high transforms over time into a state of desperate craving that is only temporarily subdued by a fix, explaining why addicts are unable to live either with or without their drug. One by one, Grisel shows how different drugs act on the brain, the kind of experiential effects they generate, and the specific reasons why each is so hard to kick.Grisel's insights lead to a better understanding of the brain's critical contributions to addictive behavior, and will help inform a more rational, coherent, and compassionate response to the epidemic in our homes and communities.

    But a medical revolution is underway that can solve this problem: Astonishing new research is revealing that the health of your brain is, to an extraordinary degree, dictated by the state of your microbiome - the vast population of organisms that live in your body and outnumber your own cells ten to one. What's taking place in your intestines today is determining your risk for any number of brain-related conditions.In BRAIN MAKER, Dr. Perlmutter explains the potent interplay between intestinal microbes and the brain, describing how the microbiome develops from birth and evolves based on lifestyle choices, how it can become "sick," and how nurturing gut health through a few easy strategies can alter your brain's destiny for the better. With simple dietary recommendations and a highly practical program of six steps to improving gut ecology, BRAIN MAKER opens the door to unprecedented brain health potential.

    Now, in this much anticipated book, he documents the science and the politics that has led to the pandemic of chronic disease over the last 30 years.In the late 1970s when the government mandated we get the fat out of our food, the food industry responded by pouring more sugar in. The result has been a perfect storm, disastrously altering our biochemistry and driving our eating habits out of our control.To help us lose weight and recover our health, Lustig presents personal strategies to readjust the key hormones that regulate hunger, reward, and stress; and societal strategies to improve the health of the next generation. Compelling, controversial, and completely based in science, Fat Chance debunks the widely held notion to prove “a calorie is NOT a calorie”, and takes that science to its logical conclusion to improve health worldwide.

    Weed. Bud. Whatever you choose to call it, it’s been a health aid, comfort, and life-enhancer for humankind for more than three thousand years. But while cannabis is used by hundreds of millions of people around the world, more than a century of prohibition has resulted in confusion about its status: Is it healthy? Is it medicinal? Will it make you crazy?In this fun, illuminating book, cannabis journalist Amanda Siebert delves deep into the latest research to separate marijuana fact from fiction, revealing ten evidence-based ways this potent little plant can improve your life. She speaks with some of the world’s top researchers, medical professionals, and consultants to answer questions such as: Can cannabis help you get a full night’s sleep? Does it aid in exercise and weight loss? Can it really cure cancer? She also offers practical advice for enjoying its benefits, including easy-to-follow, step-by-step instructions for consumption and dosage, as well as examples of real people who have used this drug to enhance their lives. Cannabis, it turns out, could be life-changing: it can enrich any diet, slow down aging, and even spice things up in the bedroom.

    But are there limits to what we can discover about our physical universe?In this very personal journey to the edges of knowledge, Marcus du Sautoy investigates how leading experts in fields from quantum physics and cosmology, to sensory perception and neuroscience, have articulated the current lie of the land. In doing so, he travels to the very boundaries of understanding, questioning contradictory stories and consulting cutting edge data.Is it possible that we will one day know everything? Or are there fields of research that will always lie beyond the bounds of human comprehension? And if so, how do we cope with living in a universe where there are things that will forever transcend our understanding?In What We Cannot Know, Marcus du Sautoy leads us on a thought-provoking expedition to the furthest reaches of modern science. Prepare to be taken to the edge of knowledge to find out if there’s anything we truly cannot know.

    Contrary to what the glossy magazines would have us believe, we do not enjoy potato chips because they crunch just like the insects our forebears snacked on. As Zuk argues, such beliefs incorrectly assume that we’re stuck—finished evolving—and have been for tens of thousands of years. She draws on fascinating evidence that examines everything from adults’ ability to drink milk to the texture of our ear wax to show that we’ve actually never stopped evolving. Our nostalgic visions of an ideal evolutionary past in which we ate, lived, and reproduced as we were “meant to” fail to recognize that we were never perfectly suited to our environment. Evolution is about change, and every organism is full of trade-offs.From debunking the caveman diet to unraveling gender stereotypes, Zuk gives an analysis of widespread paleofantasies and the scientific evidence that undermines them, all the while broadening our understanding of our origins and what they can really tell us about our present and our future.

    Ratey, MD.Did you know you can beat stress, lift your mood, fight memory loss, sharpen your intellect, and function better than ever simply by elevating your heart rate and breaking a sweat? The evidence is incontrovertible: Aerobic exercise physically remodels our brains for peak performance. In SPARK, John J. Ratey, M.D., embarks upon a fascinating and entertaining journey through the mind-body connection, presenting startling research to prove that exercise is truly our best defense against everything from depression to ADD to addiction to aggression to menopause to Alzheimer's. Filled with amazing case studies (such as the revolutionary fitness program in Naperville, Illinois, which has put this school district of 19,000 kids first in the world of science test scores), SPARK is the first book to explore comprehensively the connection between exercise and the brain. It will change forever the way you think about your morning run---or, for that matter, simply the way you think

    In Papua New Guinea, a primitive tribe is nearly obliterated by a sickness whose chief symptom is uncontrollable laughter. Across Europe, millions of sheep rub their fleeces raw before collapsing. In England, cows attack their owners in the milking parlors, while in the American West, thousands of deer starve to death in fields full of grass.What these strange conditions–including fatal familial insomnia, kuru, scrapie, and mad cow disease–share is their cause: prions. Prions are ordinary proteins that sometimes go wrong, resulting in neurological illnesses that are always fatal. Even more mysterious and frightening, prions are almost impossible to destroy because they are not alive and have no DNA–and the diseases they bring are now spreading around the world.In The Family That Couldn’t Sleep, essayist and journalist D. T. Max tells the spellbinding story of the prion’s hidden past and deadly future

    Each page offers simple activities that help you understand the roles of your “happy chemicals”—serotonin, dopamine, oxytocin, and endorphin. You’ll also learn how to build new habits by rerouting the electricity in your brain to flow down a new pathway, making it even easier to trigger these happy chemicals and increase feelings of satisfaction when you need them most. Filled with dozens of exercises that will help you reprogram your brain, Habits of a Happy Brain shows you how to live a happier, healthier life!

    microbe.” —The Wall Street Journal   Did the Black Death destroy medieval Europe? Did cholera pave the way for modern Manhattan? Did yellow fever help end the slave trade? Remarkably, the answer to all of these questions is yes. Time and again, diseases have impacted the course of human history in surprisingly powerful ways. From influenza to smallpox, from tuberculosis to yellow fever, Bryn Barnard describes the symptoms and paths of the world’s worst diseases—and how the epidemics they spawned have changed history forever.   Filled with fascinating, often gory details about disease and history, Outbreak! is a wonderful combination of science and history.

    This amazing organ has unique powers to make predictions about the future, form relationships with other people, adapt to rapidly changing circumstances, and so much more. We all have a basic conception of how our brains function, but when did you last dive into the fascinating world of neuroscience to truly understand the inner workings of your mind? For decades, the field of neuroscience has been in a near-constant state of disruptive transformation, as we continually learn more about our incredible brains. Thanks to rapid advances in technology and in our understanding of the brain, today’s neuroscience research goes far beyond trying to understand how the brain works, and into the search for proven ways to optimize brain performance. In Your Best Brain, Professor John J. Medina - an award-winning scientist, New York Times best-selling author, and leading advocate for brain research - delivers 24 exciting lectures that probe the origins of consciousness, memory, emotion, attention, intelligence, and beyond. He focuses on five key areas of study in neuroscience: the brain’s physical structure and function, and how it enabled us to become the planet’s apex predator; the ways in which the brain processes information, and how that relates to intelligence; the intricacies of emotions and socialization, and how empathy is a vital survival mechanism; how our brains develop and change throughout our lifetimes; and how we can best use and expand our cerebral processing performance. After gaining a thorough understanding of the science behind your best brain, you’ll learn scientifically proven methods for improving your memory, boosting your creativity, and keeping your mind sharp for years to come.