It is the history of who you are and how you came to be. It is unique to you, as it is to each of the 100 billion modern humans who have ever drawn breath. But it is also our collective story, because in every one of our genomes we each carry the history of our species births, deaths, disease, war, famine, migration, and a lot of sex. Since scientists first read the human genome in 2001, it has been subject to all sorts of claims, counterclaims, and myths. In fact, as Adam Rutherford explains, our genomes should be read not as instruction manuals, but as epic poems. DNA determines far less than we have been led to believe about us as individuals, but vastly more about us as a species. In this captivating journey through the expanding landscape of genetics, Adam Rutherford reveals what our genes now tell us about history, and what history tells us about our genes. From Neanderthals to murder, from redheads to race, dead kings to plague, evolution to epigenetics, this is a demystifying and illuminating new portrait of who we are and how we came to be."

    When Adina and her family are forced to flee Cologne to escape the vicious menace of German invasion in 1938, leaving their luxurious lifestyle is painful. Harder still is finding herself a refugee in a foreign country. But Adina is a compassionate and determined girl and as they settle into a new life in the Midlands she finds the strength to survive. However, her brother and sister aren't so lucky and their family ties are stretched to breaking point. And then Adina runs the risk of losing her family forever when she is drawn towards the one man she should never fall in love with...

    This was the world of medicine when Thomas Dent Mütter began his trailblazing career as a plastic surgeon in Philadelphia during the middle of the nineteenth century.Although he died at just forty-eight, Mütter was an audacious medical innovator who pioneered the use of ether as anesthesia, the sterilization of surgical tools, and a compassion-based vision for helping the severely deformed, which clashed spectacularly with the sentiments of his time.   Brilliant, outspoken, and brazenly handsome, Mütter was flamboyant in every aspect of his life. He wore pink silk suits to perform surgery, added an umlaut to his last name just because he could, and amassed an immense collection of medical oddities that would later form the basis of Philadelphia’s Mütter Museum. Cristin O’Keefe Aptowicz chronicles how Mütter’s efforts helped establish Philadelphia as a global mecca for medical innovation—despite intense resistance from his numerous rivals.

    Boss of the Richardson Gang and rival of the Krays, to cross him would result in brutal repercussions. Famously arrested on the day England won the World Cup in 1966, his trial heard he allegedly used iron bars, bolt cutters and electric shocks on his enemies.The Last Gangster is Richardson’s frank account of his largely untold life story, finished just before his death in September 2012. He shares the truth behind the rumours and tells of his feuds with the Krays for supremacy, undercover missions involving politicians, many lost years banged up in prison and reveals shocking secrets about royalty, phone hacking, bent coppers and the infamous black box.Straight up, shocking and downright gripping, this is the ultimate exposé on this legendary gangster and his extraordinary life.

     Early studies of the functions of the human brain used a simple method: wait for misfortune to strike-strokes, seizures, infectious diseases, lobotomies, horrendous accidents-and see how the victim coped. In many cases survival was miraculous, and observers could only marvel at the transformations that took place afterward, altering victims' personalities. An injury to one section can leave a person unable to recognize loved ones; some brain trauma can even make you a pathological gambler, pedophile, or liar. But a few scientists realized that these injuries were an opportunity for studying brain function at its extremes. With lucid explanations and incisive wit, Sam Kean explains the brain's secret passageways while recounting forgotten stories of common people whose struggles, resiliency, and deep humanity made modern neuroscience possible.

    By allowing women to control their fertility, the birth control pill has revolutionized women's lives. Women are going to college, graduating, and entering the workforce in greater numbers than ever before, and there's good reason to believe that the birth control pill has a lot to do with this. But there's a lot more to the pill than meets the eye.Although women go on the pill for a small handful of targeted effects (pregnancy prevention and clearer skin, yay!), sex hormones can't work that way. Sex hormones impact the activities of billions of cells in the body at once, many of which are in the brain. There, they play a role in influencing attraction, sexual motivation, stress, hunger, eating patterns, emotion regulation, friendships, aggression, mood, learning, and more. This means that being on the birth control pill makes women a different version of themselves than when they are off of it. And this is a big deal. For instance, women on the pill have a dampened cortisol spike in response to stress. While this might sound great (no stress!), it can have negative implications for learning, memory, and mood. Additionally, because the pill influences who women are attracted to, being on the pill may inadvertently influence who women choose as partners, which can have important implications for their relationships once they go off it. Sometimes these changes are for the better . . . but other times, they're for the worse. By changing what women's brains do, the pill also has the ability to have cascading effects on everything and everyone that a woman encounters. This means that the reach of the pill extends far beyond women's own bodies, having a major impact on society and the world.This paradigm-shattering book provides an even-handed, science-based understanding of who women are, both on and off the pill. It will change the way that women think about their hormones and how they view themselves. It also serves as a rallying cry for women to demand more information from science about how their bodies and brains work and to advocate for better research. This book will help women make more informed decisions about their health, whether they're on the pill or off of it.

    Your brain can't function. You are asked to make decisions about treatment almost immediately, when you are not in your right mind. And yet you pull yourself together and start asking questions. Beside you is your doctor, whose job it is to solve the awful puzzle of bone marrow gone wrong. The two of you are in it together. In When Blood Breaks Down, Mikkael Sekeres, a leading cancer specialist, takes readers on the journey that patient and doctor travel together.Sekeres, who writes regularly for the Well section of the New York Times, tells the compelling stories of three people who receive diagnoses of adult leukemia within hours of each other: Joan, a 48-year-old surgical nurse, a caregiver who becomes a patient; David, a 68-year-old former factory worker who bows to his family's wishes and pursues the most aggressive treatment; and Sarah, a 36-year-old pregnant woman who must decide whether to undergo chemotherapy and put her fetus at risk. We join the intimacy of the conversations Sekeres has with his patients, and watch as he teaches trainees. Along the way, Sekeres also explores leukemia in its different forms and the development of drugs to treat it--describing, among many other fascinating details, the invention of the bone marrow transplant (first performed experimentally on beagles) and a treatment that targets the genetics of leukemia.The lessons to be learned from leukemia, Sekeres shows, are not merely medical; they teach us about courage and grace and defying the odds.

    A politically charged coroner's inquest failed to determine a definitive cause of death, and the following civil action continued to expose sordid details of the couple's lives. More than half a century later, the story was all but forgotten when local resident Diane McLellan spied an old photograph at a yard sale and became obsessed with solving the mystery. Her enthusiastic sleuthing captured the attention of Southern Pines resident and journalist Steve Bouser, who takes readers back to those blustery winter days so long ago in the search to reveal what really happened to Elva Statler Davidson.

    But they weren’t there to protest. They were there to watch the World Chess Championship between Norway's Magnus Carlsen and Russia's Sergey Karjakin—what by the time it was over would be front-page news and thought by many the greatest finish in chess history. The story lines were riveting. The championship hadn’t been hosted in New York City, the de facto world capital of the sport, in more than two decades. With both Carlsen and Karjakin just 25 years old, the tournament organizers were billing it as a battle of the millennials—the first time the championship had been waged among the generation that grew up playing chess primarily against computers. And perhaps most intriguing were all the geopolitical connections to the match. Originally from Crimea, Karjakin had recently repatriated to Russia under the direct assistance of Putin. Carlsen, meanwhile, had expressed admiration for Donald Trump, and his first move of the tournament he played with a smirk what's called a Trompowsky Attack. Then there was the Russian leader of the World Chess Federation being barred from attending due to US sanctions, and chess fanatic and Trump adviser Peter Thiel being called on to make the honorary first move in sudden death. That the tournament required sudden death was a shock. Oddsmakers had given Carlsen, the defending champion, an 80% chance of winning. It would take everything he had to retain his title. In doing so, he would firmly make his case to be considered the greatest player chess has ever seen. Author Brin-Jonathan Butler was granted unique access to the two-and-half-week tournament and watched every move. In The Grandmaster, he aims to do for Magnus Carlsen what Norman Mailer did for Muhammed Ali in The Fight, John McPhee did for Arthur Ashe in Levels of the Game, and David Foster Wallace did for Roger Federer in his famous New York Times Magazine profile. Butler captures one of the world’s greatest sportsmen at the height of their powers, and attempts to decipher the secret to that greatness.

    But in the inevitable condition of aging and death, the goals of medicine seem too frequently to run counter to the interest of the human spirit. Nursing homes, preoccupied with safety, pin patients into railed beds and wheelchairs. Hospitals isolate the dying, checking for vital signs long after the goals of cure have become moot. Doctors, committed to extending life, continue to carry out devastating procedures that in the end extend suffering.Gawande, a practicing surgeon, addresses his profession's ultimate limitation, arguing that quality of life is the desired goal for patients and families. Gawande offers examples of freer, more socially fulfilling models for assisting the infirm and dependent elderly, and he explores the varieties of hospice care to demonstrate that a person's last weeks or months may be rich and dignified.

    When their parents commit Phoebe to a notorious asylum, Charlotte knows there's more to the story than madness. Shedding her identity to become an anonymous inmate, "Woman Ninety-Nine," Charlotte uncovers dangerous secrets. Insanity isn't the only reason her fellow inmates were put away - and those in power will do anything to keep the truth, or Charlotte, from getting out.

    The book that finally cracks the case. Ben Smart. Olivia Hope. Scott Watson. Unmissable. Undeniable. Unprecedented. Unexpected. Note from author: "This book contains quotes from original police witness statements. No two witnesses ever see the crime from exactly the same angle, so differences between statements are expected. Sometimes one statement can have a crucial detail that others have missed. That's why I included what appear to be 'repetitive' statements by a number of witnesses. So you can see the overall similarities and weight of evidence, but also any unique details. Sometimes witness statements are relevant to different parts of the story, so just as in a murder trial, readers may find a statement being referred to more than once.In a crime story, the devil can be in the detail. The statements are quoted in the authentic spelling of the witness - as important legal records they don't get 'proofed'. The court trial lasted 12 weeks and involved 30,000 pages of documents. I have distilled that down to 372 pages but it is still a complex story. Think of yourself as a juror, sifting the evidence."Previous books on this case have concentrated on picking apart the police version of events given in Court. That's a legalistic technique of creating 'doubt'. I ask a different question: Forget about the court case, do the original witness statements including ones never used in court show us what happened? The answer, I suggest, is "Yes", and you are about to find out for yourself..."

    The defacto boss of the Colombo Mafia family since the 1970s, he oversaw gang wars, murders, and major rackets, even from prison. He is suspected of personally murdering as many as 60 people and ordering the hits of hundreds more. Sentenced to 139 years in the fed, he continued to exert power over a vast criminal empire from behind bars. His brutal rise and bloody reign is the stuff of legend.In this blistering street-level account, “Mafia survivor” Frank Dimatteo teams up with true-crime master Michael Benson to take down one of the most notorious figures in the American La Cosa Nostra. This is the real inside story of Carmine “The Snake” Persico,  from his crime-filled childhood on the streets of Brooklyn to the long-term jail sentences that didn’t stop him from controlling his criminal empire with the help of his brother, the equally kill-crazy Alphonse "Allie Boy" Persico. His deadly teen years as leader of the fearsome Garfield Boys. His recruitment into the Profaci—later the Colombo—crime family. His bloody  betrayal of the Gallo brothers. His role in the hair-raising ambush-slaying of Albert Anastasia—the Lord High Executioner of Murder, Inc.—as he sat in a barbershop chair getting a shave. The terror he struck into the hearts of the New York Mafia’s other families, and even his own crews. And the many courtroom trials where Persico walked after witnesses came down with sudden cases of amnesia.Today, Carmine “The Snake” Persico schmoozes with Ponzi king Bernard Madoff behind bars where at age 84 his legend, packed as it is with cold-blooded brutality, continues to inspire goodfellas everywhere.

    The son of legendary Irish and World Champion Stephen Roche, Nicolas had to fight to make it as a professional and even harder to make his mark as his own man on this toughest of competitive sports. His rise up the ranks has been meteoric, with top 15 finishes in both the Tour de France and the Vuelta a España in 2010, but his attitude to his chosen profession has remained undimmed. Honest, eloquent and passionate about how the cycling world should be, Nicolas has gained acclaim and a devoted fan following for his Tour diaries serialised in the Irish Independent. Now a major contender for a podium finish in a grand tour, Nicolas is ready to expand on those diaries and to tell in full the story of life in the peloton and of the remarkable events that have brought him this far. From furious spats with teammates and exhilarating races against the world's best, this is a gripping cycling adventure and sportsman's tale.

    Buting explains the flaws in America’s criminal justice system and lays out a provocative, persuasive blue-print for reform.Over his career, Jerome F. Buting has spent hundreds of hours in courtrooms representing defendants in criminal trials. When he agreed to join Dean Strang as co-counsel for the defense in Steven A. Avery vs. State of Wisconsin, he knew a tough fight lay ahead. But, as he reveals in Illusion of Justice, no-one could have predicted just how tough and twisted that fight would be—or that it would become the center of the documentary Making a Murderer, which made Steven Avery and Brendan Dassey household names and thrust Buting into the spotlight.Buting’s powerful, riveting boots-on-the-ground narrative of Avery’s and Dassey’s cases becomes a springboard to examine the shaky integrity of law enforcement and justice in the United States, which Buting has witnessed firsthand for more than 35 years. From his early career as a public defender to his success overturning wrongful convictions working with the Innocence Project, his story provides a compelling expert view into the high-stakes arena of criminal defense law; the difficulties of forensic science; and a horrifying reality of biased interrogations, coerced or false confessions, faulty eyewitness testimony, official misconduct, and more.Combining narrative reportage with critical commentary and personal reflection, Buting explores his professional and personal motivations, career-defining cases—including his shocking fifteen-year-long fight to clear the name of another man wrongly accused and convicted of murder—and what must happen if our broken system is to be saved. Taking a place beside Just Mercy and The New Jim Crow, Illusion of Justice is a tour-de-force from a relentless and eloquent advocate for justice who is determined to fulfill his professional responsibility and, in the face of overwhelming odds, make America’s judicial system work as it is designed to do.