In 2013, the New York Times published an obituary for Yvonne Brill. It began: “She made a mean beef stroganoff, followed her husband from job to job, and took eight years off from work to raise three children.” It wasn’t until the second paragraph that readers discovered why the Times had devoted several hundred words to her life: Brill was a brilliant rocket scientist who invented a propulsion system to keep communications satellites in orbit, and had recently been awarded the National Medal of Technology and Innovation. Among the questions the obituary—and consequent outcry—prompted were, Who are the role models for today’s female scientists, and where can we find the stories that cast them in their true light?      Headstrong delivers a powerful, global, and engaging response. Covering Nobel Prize winners and major innovators, as well as lesser-known but hugely significant scientists who influence our every day, Rachel Swaby’s vibrant profiles span centuries of courageous thinkers and illustrate how each one’s ideas developed, from their first moment of scientific engagement through the research and discovery for which they’re best known. This fascinating tour reveals these 52 women at their best—while encouraging and inspiring a new generation of girls to put on their lab coats.

    Readers will develop an understanding of the multiple research methods and strategies used in education and related fields, the ability to read and critically evaluate published research, and the ability to write a proposal, construct a questionnaire, and conduct an empirical research study on their own.

    The Eighth Edition has been thoroughly revised and updated and is available in both print and e-book formats.Janeway s Immunobiology continues to set the standard for currency and authority with its clear writing style and organization, uniform art program, and scientific accuracy. It presents a consistent point of view throughout that of the host s interaction with an environment containing many species of potentially harmful microorganisms. The full-color art program is conceptually coherent and illustrates the processes and mechanisms underlying the concepts in the text. The 16 chapters in this readable, accessible textbook are organized and presented in such a way as to help deliver a complete one-semester immunology course, beginning with innate immunity, then moving to adaptive immunity, and ending with applied clinical immunology.Discussion questions are provided at the end of Chapters 2 to 16. These questions can be used for review, or as the basis for discussion in class or in informal study groups. Summaries conclude each section and each chapter. As in previous editions, a caduceus icon in the margins indicates topics which are correlated to Case Studies in Immunology, Sixth Edition by Geha and Notarangelo.New in the Eighth EditionInnate immunity has been updated and expanded and is now presented in two separate chapters (Chapters 2 and 3), as well as being further emphasized in the rest of the textbook. Chapter 2 covers antimicrobial peptides and the complement system, and Chapter 3 deals with cellular innate receptors and cell-mediated innate immunity (e.g. TLRs, phagocytosis, NK cells, interferon production, innate-like lymphocytes). The section on complement has been reworked and reconceived explaining the lectin pathway first making it easier to teach by placing it into the context of innate recognition. Evolution is now incorporated throughout the text, helping students see similar strategies used by different organisms. The text and figures of Chapter 7 Signaling Through Immune System Receptors have been revised to present a cohesive synthesis of signaling for immunology, focusing on improved illustration of antigen recognition signaling and lymphocyte activation. Signaling through other receptors is dealt with wherever appropriate throughout the book. Updated chapter on B-cell immune responses (Chapter 10), especially on trafficking of B cells in peripheral lymphoid organs (e.g. lymph nodes) and the locations at which they encounter antigen. Coverage of mucosal immunity (Chapter 12) has been brought up to date, including responses to the commensal microbiota and the role of specialized dendritic cells and the regulatory T cells in maintaining tolerance to food antigens and commensal bacteria. Chapter 13, Failures of Host Defense Mechanisms, has been reorganized and revised to structure an understanding of primary immunodeficiencies in the context of developmental pathways. Chapter 16, Manipulation of the Immune Response, has been heavily revised to include a greater emphasis on clinical issues and a complete update of immunotherapeutics and vaccines. Many new and revised figures illustrate the processes and mechanisms underlying the concepts presented in the text. The icons used have been updated and expanded to incorporate a new emphasis on signaling pathways. New references have been added throughout the text.

    Beginning with the study of DNA in Egyptian mummies in the early 1980s and culminating in the sequencing of the Neanderthal genome in 2010, Neanderthal Man describes the events, intrigues, failures, and triumphs of these scientifically rich years through the lens of the pioneer and inventor of the field of ancient DNA.We learn that Neanderthal genes offer a unique window into the lives of our hominin relatives and may hold the key to unlocking the mystery of why humans survived while Neanderthals went extinct. Drawing on genetic and fossil clues, Pääbo explores what is known about the origin of modern humans and their relationship to the Neanderthals and describes the fierce debate surrounding the nature of the two species’ interactions. His findings have not only redrawn our family tree, but recast the fundamentals of human history—the biological beginnings of fully modern Homo sapiens, the direct ancestors of all people alive today.A riveting story about a visionary researcher and the nature of scientific inquiry, Neanderthal Man offers rich insight into the fundamental question of who we are.

    Each bodily function is discussed from a variety of viewpoints: scientific, anthropological, historical, mythological, sociological, and artistic. Topics include constipation, the history and evolution of toilet paper, farting, urine, earwax, smegma, and many other engrossing topics!You think you know shit? How about: Scatological Lives of the Greats; Thomas Crapper, Closet Genius; Excrement in Psychoanalysis; Excretal Customs Worldwide; Bodily Functions in Literature & Cinema; Historical Applications of Excrement....Spend a little time getting to know yourself! Read all about Feces, Flatus, Vomit, Urine, Mucus, Menstruation, Saliva, Sweat, & more!

    Weschler thoroughly explains the empowering Fertility Awareness Method, which in only a couple minutes a day allows a woman to:-Enjoy highly effective, scientifically proven birth control without chemicals or devices-Maximize her chances of conception or expedite fertility treatment by identifying impediments to conception-Increase the likelihood of choosing the gender of her baby-Gain control of her sexual and gynecological health

    About The Author: Henry Gray, F.R.S., Fellow of the royal college of Surgeons: Lecturer on anatomy at St. George?s Hospital Medical School. Table Of Contents: Descriptive and Surgical Anatomy The Articulations Muscles and Fasclae The Blood-vascular system The Lymphatics The Nervous system The Organs of special sense The Organs of Digestion The Organs of voice and respiration The urinary organs The Male Organs of Generation The Female Organs of Generation The Surgical Anatomy of Hernia Surgical Anatomy of the Perinaeum General Anatomy or Histology Embryology

    Another bolts across a busy parking lot, turns and smiles at his mom. An eighteen-year-old student bursts into tears when asked to change activities at school. Sound familiar? These and other common behavior issues in children with Down syndrome can quickly become engrained and may even persist into adulthood. No parent wants that to happen, and thankfully, help is available! Dr. David Stein, a psychologist and Co-Director of the Down Syndrome Program at Boston Children's Hospital, shares his approach to behavior management in this new book for parents. Supporting Positive Behavior in Children and Teens with Down Syndrome examines how the brain of a person with Down syndrome works, how those differences impact behavior, and why bad behavior should not be viewed as a willful act. Governed by this new awareness, parents are in a better position to change and manage their child's behavior using these guiding principles: [[Be proactive, not reactive [[Be consistent [[Use visual schedules & Social Stories to direct behavior [[Develop a token reward chart [[Keep gut reactions in check [[Teach siblings to ignore bad behavior [[Learn effective disciplinary techniques [[Know when professional help is needed Some of these parenting concepts are intuitive, others are not, but when they are followed consistently, children and teens with Down syndrome do their best behaviorally and the parent-child relationship remains as positive and loving as it should be.

    Mainstream science--as well as religious and cultural institutions--has maintained that men and women evolved in families in which a man's possessions and protection were exchanged for a woman's fertility and fidelity. But this narrative is collapsing. Fewer and fewer couples are getting married, and divorce rates keep climbing as adultery and flagging libido drag down even seemingly solid marriages.How can reality be reconciled with the accepted narrative? It can't be, according to renegade thinkers Christopher Ryan and Cacilda Jethá. While debunking almost everything we "know" about sex, they offer a bold alternative explanation in this provocative and brilliant book.Ryan and Jethá's central contention is that human beings evolved in egalitarian groups that shared food, child care, and, often, sexual partners. Weaving together convergent, frequently overlooked evidence from anthropology, archaeology, primatology, anatomy, and psychosexuality, the authors show how far from human nature monogamy really is. Human beings everywhere and in every era have confronted the same familiar, intimate situations in surprisingly different ways. The authors expose the ancient roots of human sexuality while pointing toward a more optimistic future illuminated by our innate capacities for love, cooperation, and generosity.With intelligence, humor, and wonder, Ryan and Jethá show how our promiscuous past haunts our struggles over monogamy, sexual orientation, and family dynamics. They explore why long-term fidelity can be so difficult for so many; why sexual passion tends to fade even as love deepens; why many middle-aged men risk everything for transient affairs with younger women; why homosexuality persists in the face of standard evolutionary logic; and what the human body reveals about the prehistoric origins of modern sexuality.In the tradition of the best historical and scientific writing, Sex at Dawn unapologetically upends unwarranted assumptions and unfounded conclusions while offering a revolutionary understanding of why we live and love as we do.

    In a way, you already know them. Only you don’t – not really. In a sense, they are you. Only they’re not entirely. They inform and shape the most important decisions in your life. But you’re almost certainly unaware of their intervention. They are the Ten Types of Human. Who are they? What are they for? How did they get into your head? We want to believe that there are some things we would never do. We want to believe that there are others we always would. But how can we be sure? What are our limits? Do we have limits?The answer lies with the Ten Types of Human: the people we become when we are faced with life's most difficult decisions. But who or what are these Types? Where do they come from? How did they get into our heads?The Ten Types of Human is a pioneering examination of human nature. It looks at the best and worst that human beings are capable of, and asks why. It explores the frontiers of the human experience, excavating the forces that shape our thoughts and actions in extreme situations. It begins in a courtroom and journeys across four continents and through the lives of some exceptional people, in search of answers.Mixing cutting-edge neuroscience, social psychology and visceral true stories, The Ten Types of Human is at once a provocation and a roadmap of the hidden parts of us. It is a book to inspire; to refashion our understanding of our many selves and semblances; and ultimately to find fresh ways to be free.

    Whether they are riding, breathing, or making bubbles, one thing is for sure—animals use bubbles in amazing ways.

    THE NEW YORK TIMES BESTSELLERUnlock the secret to extraordinary health by reducing high uric acid levels—the hidden risk you didn't know you had—by the author of Grain Brain and Brain Wash.What do obesity, insulin resistance, diabetes, fatty liver disease, hypertension, cardiovascular disease, stroke, neurological disorders, and premature death have in common? All can be stoked by high uric acid levels. Our most respected scientific literature is bursting with evidence that elevated uric acid levels lie at the root of many pervasive health conditions, but mainstream medicine for the most part remains unaware of this connection. This is especially alarming because a large number of Americans don’t know they are suffering from increased levels, putting them at risk for developing or exacerbating potentially life-threatening illnesses. Offering an engaging blend of science and practical advice, Drop Acid exposes the deadly truth about uric acid and teaches invaluable strategies to manage its levels, including how to:Reduce fructose and foods high in “purines” through simple dietary edits Lower uric acid levels through natural hacks like consuming tart cherries, vitamin C, quercetin, and coffeeIdentify common pharmaceuticals that threaten to increase uric acidImplement lifestyle interventions, like restorative sleep and exerciseEasily test your uric acid levels at home—a test routinely performed in your doctor’s office during regular check-ups but typically ignoredFeaturing the groundbreaking “LUV” (Lower Uric Values) diet, 35 delicious recipes, self-assessment quizzes, and a 21-day program for dropping levels, Drop Acid empowers readers with the information they need to address this hidden danger and live longer, leaner, and healthier lives.

    But despite the hype, Tyrannosaurus and the other tyrannosaurs are fascinating animals in their own right, and are among the best-studied of all dinosaurs.Tyrannosaurs started small, but over the course of 100 million years evolved into the giant carnivorous bone-crushers that continue to inspire awe in palaeontologists, screenplay writers, sci-fi novelists and the general public alike. Tyrannosaurus itself was truly impressive; it topped six tons, was more than 12m (40 feet) long, and had the largest head and most powerful bite of any land animal in history.The Tyrannosaur Chronicles tracks the rise of these dinosaurs, and presents the latest research into their biology, showing off more than just their impressive statistics - tyrannosaurs had feathers and fought and even ate each other. This book presents the science behind this research; it tells the story of the group through their anatomy, ecology and behaviour, exploring how they came to be the dominant terrestrial predators of the Mesozoic and, in more recent times, one of the great icons of biology.

    That bomb had more power than 20,000 tons of T.N.T. It had more than two thousand times the blast power of the British Grand Slam, which is the largest bomb ever yet used in the history of warfare".These fateful words of the President on August 6th, 1945, marked the first public announcement of the greatest scientific achievement in history. The atomic bomb, first tested in New Mexico on July 16, 1945, had just been used against a military target.On August 6th, 1945, at 8:15 A.M., Japanese time, a B-29 heavy bomber flying at high altitude dropped the first atomic bomb on Hiroshima. More than 4 square miles of the city were instantly and completely devastated. 66,000 people were killed, and 69,000 injured.On August 9th, three days later, at 11:02 A.M., another B-29 dropped the second bomb on the industrial section of the city of Nagasaki, totally destroying 1 1/2 square miles of the city, killing 39,000 persons, and injuring 25,000 more.On August 10, the day after the atomic bombing of Nagasaki, the Japanese government requested that it be permitted to surrender under the terms of the Potsdam declaration of July 26th which it had previously ignored.

    Right?! Machine Learning is a branch of computer science that wants to stop programming computers using a detailed list of commands to follow blindly. Instead, their aim is to implement high-level routines that teach computers how to approach new and unknown problems – these are called algorithms. In practice, they want to give computers the ability to Learn and to Adapt. We can use these algorithms to obtain insights, recognize patterns and make predictions from data, images, sounds or videos we have never seen before – or even knew existed. Unfortunately, the true power and applications of today’s Machine Learning Algorithms remain deeply misunderstood by most people. Through this book I want fix this confusion, I want to shed light on the most relevant Machine Learning Algorithms used in the industry. I will show you exactly how each algorithm works, why it works and when you should use it. Supervised Learning Algorithms K-Nearest Neighbour Naïve Bayes Regressions Unsupervised Learning Algorithms: Support Vector Machines Neural Networks Decision Trees