Conceived, written, and directed by a little-known filmmaker named George Lucas, the movie originally called The Star Wars quickly drew blocks-long lines, bursting box-office records and ushering in a new way for movies to be made, marketed, and merchandised. It is now one of the most adored-and successful-movie franchises of all time.Now, the author of the bestselling biography Jim Henson delivers a long-awaited, revelatory look into the life and times of the man who created Luke Skywalker, Han Solo, and Indiana Jones.If Star Wars wasn't game-changing enough, Lucas went on to create another blockbuster series with Indiana Jones, and he completely transformed the world of special effects and the way movies sound. His innovation and ambition forged Pixar and Lucasfilm, Industrial Light & Magic, and THX sound.Lucas's colleagues and competitors offer tantalizing glimpses into his life. His entire career has been stimulated by innovators including Steven Spielberg and Francis Ford Coppola, actors such as Harrison Ford, and the very technologies that enabled the creation of his films-and allowed him to keep tinkering with them long after their original releases. Like his unforgettable characters and stories, his influence is unmatched.

    Nobel Prize winner Kandel intertwines cogntive psychology, neuroscience, and molecular biology with his own quest to understand memory.

    Two years later, Clea Koff, a twenty-three-year-old forensic anthropologist, left the safe confines of a lab in Berkeley, California, to serve as one of sixteen scientists chosen by the United Nations to unearth the physical evidence of the Rwandan genocide. Over the next four years, Koff’s grueling investigations took her across geography synonymous with some of the worst crimes of the twentieth century. The Bone Woman is Koff’s unflinching, riveting account of her seven UN missions to Bosnia, Croatia, Kosovo, and Rwanda, as she shares what she saw, how it affected her, who was prosecuted based on evidence she found, and what she learned about the world. Yet even as she recounts the hellish nature of her work and the heartbreak of the survivors, she imbues her story with purpose, humanity, and a sense of justice. A tale of science in service of human rights, The Bone Woman is, even more profoundly, a story of hope and enduring moral principles.

    The next morning, things take a sharp turn as she’s led from work to the emergency room. By the end of the week, a neurologist delivers a devastating prognosis: Sarah suffered a traumatic brain injury that has caused her IQ to plummet, with no hope of recovery. Her brain has irrevocably changed.Afraid of judgment and deemed no longer fit for work, Sarah isolates herself from the outside world. She spends months at home, with her dogs as her only source of companionship, battling a personality she no longer recognizes and her shock and rage over losing simple functions she’d taken for granted. Her life is consumed by fear and shame until a chance encounter gives Sarah hope that her brain can heal. That conversation lights a small flame of determination, and Sarah begins to push back, painstakingly reteaching herself to read and write, and eventually reentering the workforce and a new, if unpredictable, life.In this highly intimate account of devastation and renewal, Sarah pulls back the curtain on life with traumatic brain injury, an affliction where the wounds are invisible and the lasting effects are often misunderstood. Over years of frustrating setbacks and uncertain triumphs, Sarah comes to terms with her disability and finds love with a woman who helps her embrace a new, accepting sense of self.

     Of the great figure in twentieth-century American history perhaps none is more complex and controversial than Malcolm X. Constantly rewriting his own story, he became a criminal, a minister, a leader, and an icon, all before being felled by assassins' bullets at age thirty-nine. Through his tireless work and countless speeches he empowered hundreds of thousands of black Americans to create better lives and stronger communities while establishing the template for the self-actualized, independent African American man. In death he became a broad symbol of both resistance and reconciliation for millions around the world. Manning Marable's new biography of Malcolm is a stunning achievement. Filled with new information and shocking revelations that go beyond the Autobiography, Malcolm X unfolds a sweeping story of race and class in America, from the rise of Marcus Garvey and the Ku Klux Klan to the struggles of the civil rights movement in the fifties and sixties. Reaching into Malcolm's troubled youth, it traces a path from his parents' activism through his own engagement with the Nation of Islam, charting his astronomical rise in the world of Black Nationalism and culminating in the never-before-told true story of his assassination. Malcolm X will stand as the definitive work on one of the most singular forces for social change, capturing with revelatory clarity a man who constantly strove, in the great American tradition, to remake himself anew.

    Instead, he finds that he has joined a new world where race is front and center. The recipient of a scholarship designed to increase black student enrollment, Tweedy soon meets a professor who bluntly questions whether he belongs in medical school, a moment that crystallizes the challenges he will face throughout his career. Making matters worse, in lecture after lecture the common refrain for numerous diseases resounds, "More common in blacks than in whites."Black Man in a White Coat examines the complex ways in which both black doctors and patients must navigate the difficult and often contradictory terrain of race and medicine. As Tweedy transforms from student to practicing physician, he discovers how often race influences his encounters with patients. Through their stories, he illustrates the complex social, cultural, and economic factors at the root of many health problems in the black community. These issues take on greater meaning when Tweedy is himself diagnosed with a chronic disease far more common among black people. In this powerful, moving, and deeply empathic book, Tweedy explores the challenges confronting black doctors, and the disproportionate health burdens faced by black patients, ultimately seeking a way forward to better treatment and more compassionate care.

    The germ revolution came after two decades of scientific virtuosity, outstanding feats of intellectual courage and bitter personal rivalries, doctors at last recognised that infectious diseases are caused by mircoscopic organisms.

    Can our world support that? What kind of world will it be? Those answering these questions generally fall into two deeply divided groups--Wizards and Prophets, as Charles Mann calls them in this balanced, authoritative, nonpolemical new book. The Prophets, he explains, follow William Vogt, a founding environmentalist who believed that in using more than our planet has to give, our prosperity will lead us to ruin. Cut back! was his mantra. Otherwise everyone will lose! The Wizards are the heirs of Norman Borlaug, whose research, in effect, wrangled the world in service to our species to produce modern high-yield crops that then saved millions from starvation. Innovate! was Borlaug's cry. Only in that way can everyone win! Mann delves into these diverging viewpoints to assess the four great challenges humanity faces--food, water, energy, climate change--grounding each in historical context and weighing the options for the future. With our civilization on the line, the author's insightful analysis is an essential addition to the urgent conversation about how our children will fare on an increasingly crowded Earth.

    In this compelling memoir, his first wife, Jane Hawking, relates the inside story of their extraordinary marriage. As Stephen's academic renown soared, his body was collapsing under the assaults of a motor neuron disease. Jane's candid account of trying to balance his 24-hour care with the needs of their growing family reveals the inner strength of the author, while the self-evident character and achievements of her husband make for an incredible tale presented with unflinching honesty. Jane's candor is no less apparent when the marriage finally ends in a high-profile meltdown, with Stephen leaving Jane for one of his nurses and Jane marrying an old family friend. In this exceptionally open, moving, and often funny memoir, Jane Hawking confronts not only the acutely complicated and painful dilemmas of her first marriage, but also the relationship's fault lines exposed by the pervasive effects of fame and wealth. The result is a book about optimism, love, and change that will resonate with readers everywhere.

    But the true saga of her life has never been fully told. Now, drawing on unpublished manuscripts, letters, diaries, and land and financial records, Caroline Fraser—the editor of the Library of America edition of the Little House series—masterfully fills in the gaps in Wilder’s biography. Revealing the grown-up story behind the most influential childhood epic of pioneer life, she also chronicles Wilder's tumultuous relationship with her journalist daughter, Rose Wilder Lane, setting the record straight regarding charges of ghostwriting that have swirled around the books.The Little House books, for all the hardships they describe, are paeans to the pioneer spirit, portraying it as triumphant against all odds. But Wilder’s real life was harder and grittier than that, a story of relentless struggle, rootlessness, and poverty. It was only in her sixties, after losing nearly everything in the Great Depression, that she turned to children’s books, recasting her hardscrabble childhood as a celebratory vision of homesteading—and achieving fame and fortune in the process, in one of the most astonishing rags-to-riches episodes in American letters.Spanning nearly a century of epochal change, from the Indian Wars to the Dust Bowl, Wilder’s dramatic life provides a unique perspective on American history and our national mythology of self-reliance. With fresh insights and new discoveries, Prairie Fires reveals the complex woman whose classic stories grip us to this day.WINNER OF THE PULITZER PRIZEWINNER OF THE NATIONAL BOOK CRITICS CIRCLE AWARDWINNER OF THE CHICAGO TRIBUNE HEARTLAND PRIZE FOR NON-FICTIONONE OF THE NEW YORK TIMES BOOK REVIEW'S 10 BEST BOOKS OF THE YEAROne of The New York Times Book Review's 10 Best Books of the YearThe first comprehensive historical biography of Laura Ingalls Wilder, the beloved author of the Little House on the Prairie books

    Two scientists explore the potential of a revolutionary genetics technology capable of easily and affordably manipulating DNA in human embryos to prevent specific diseases, addressing key concerns about related ethical and societal repercussions.

    Michael Mosley'This book is marvellous: buy it, share it, recommend it.... We are fortunate to have dedicated, caring and humble folks such as Doc Morgan on the Critical Care front line. We are even better off when a writer can capture all that this exciting, mad, glorious and even exasperating job means. If you work in healthcare, know somebody that does, or simply inhabit a body then this book is for you: in fact it's critical.' Peter Brindley, Professor of Critical Care Medicine, Anesthesiology, Medical Ethics University of Alberta'Just wonderful. I love the exploration of what it means to survive, at what cost and so on. Such an important factor and it's a real problem with what we do. An old surgeon once told me ‘just because we can, doesn’t mean we should. Operating is the easiest thing in the world, not doing so is incredibly challenging’. A lovely book.' Dr Nikki Stamp FRACS Cardiothoracic and Transplant Surgeon and author of Can You Die of a Broken Heart?‘An illuminating, compassionate insight into the fascinating world of intensive care.’ Leah Hazzard, author of Hard PushedCritical is an intelligent, compelling and profoundly insightful journey into the world of intensive care medicine and the lives of people who have forever been changed by it. Being critically ill means one or more of your vital organs have failed – this could be your lungs, your heart, your kidneys, gut or even your brain. Starting with the first recognised case in which a little girl was saved by intensive care in 1952 in Copenhagen, Matt writes brilliantly about the fascinating history, practices and technology in this newest of all the major medical specialties. Matt guides us around the ICU by guiding us around the body and the different organs, and in this way, we learn not only the stories of many of the patients he’s treated over the years, but also about the various functions different parts of the body.   He draws on his time spent with real patients, on the brink of death, and explains how he and his colleagues fight against the odds to help them live. Happily many of his cases have happy endings, but Matt also writes movingly about those cases which will always remain with him – the cases where the mysteries of the body proved too hard to solve, or diagnoses came too late or made no difference to the outcome.

    Throughout her life Justice Ginsburg has been (and continues to be) a prolific writer and public speaker. This book’s sampling is selected by Justice Ginsburg and her authorized biographers Mary Hartnett and Wendy W. Williams. Justice Ginsburg has written an introduction to the book, and Hartnett and Williams introduce each chapter, giving biographical context and quotes gleaned from hundreds of interviews they have conducted. This is a fascinating glimpse into the life of one of America’s most influential women.

    The niece of Theodore Roosevelt, she married a distant relative and Columbia University law student named Franklin Delano Roosevelt; he gradually ascended throughout the world of New York politics to reach the U.S. presidency in 1932. Throughout his three terms, Eleanor Roosevelt was not only intimately involved in FDR’s personal and political life, but led women’s organizations and youth movements and fought for consumer welfare, civil rights, and improved housing. During World War II she traveled with her husband to meet leaders of many powerful nations; after his death in 1945 she worked as a UN delegate, chairman of the Commission on Human Rights, newspaper columnist, Democratic party activist, world-traveler, and diplomat. By the end of her life, Eleanor Roosevelt was recognized throughout the world for her fortitude and commitment to the ideals of liberty and human rights. Her autobiography constitutes a self-portrait no biography can match for its candor and liveliness, its wisdom, tolerance, and breadth of view—a self-portrait of one of the greatest American humanitarians of our time.

    Bill Gates, Bono, and Laura Bush are only a few of the personalities who have lent their names--and opened their pocketbooks--in hopes of curing the disease. Still, in a time when every emergent disease inspires waves of panic, why aren't we doing more to eradicate one of our oldest foes? And how does a parasitic disease that we've known how to prevent for more than a century still infect 500 million people every year, killing nearly 1 million of them? In "The Fever," the journalist Sonia Shah sets out to answer these questions, delivering a timely, inquisitive chronicle of the illness and its influence on human lives. Through the centuries, she finds, we've invested our hopes in a panoply of drugs and technologies, and invariably those hopes have been dashed. From the settling of the New World to the construction of the Panama Canal, through wars and the advances of the Industrial Revolution, Shah tracks malaria's jagged ascent and the tragedies in its wake, revealing a parasite every bit as persistent as the insects that carry it. With distinguished prose and original reporting from Panama, Malawi, Cameroon, India, and elsewhere, "The Fever" captures the curiously fascinating, devastating history of this long-standing thorn in the side of humanity.