After years of misdiagnoses, doctors discovered a deadly blockage in her liver. Struggling to find  an explanation for her unusual condition, Joselin compared the medical chart of her father—who had died from a mysterious disease, ten years prior—with that of an uncle who had died under similarly strange circumstances. Delving further into the past, she discovered that her great-grandmother had displayed symptoms similar to hers before her death. Clearly, this was more than a fluke. Setting out to build a more complete picture of the illness that haunted her family, Joselin approached Dr. Christine Seidman, the head of a group of world-class genetic researchers at Harvard Medical School, for help. Dr. Seidman had been working on her family’s case for twenty years and had finally confirmed that fourteen of Joselin’s relatives carried something called a private mutation—meaning that they were the first known people to experience the baffling symptoms of a brand new genetic mutation. Here, Joselin tells the story of their gene: the lives it claimed and the future of genomic medicine with the potential to save those that remain. Digging into family records and medical history, conducting interviews with relatives and friends, and reflecting on her own experiences with the Harvard doctor, Joselin pieces together the lineage of this deadly gene to write an exploration of family, history, and love.

    And in so doing, he offers something for everyone, no matter which strand draws you in.”—The New York Times Book ReviewIn November 2014, thirteen members of the Biden family gathered on Nantucket for Thanksgiving, a tradition they had been celebrating for the past forty years; it was the one constant in what had become a hectic, scrutinized, and overscheduled life. The Thanksgiving holiday was a much-needed respite, a time to connect, a time to reflect on what the year had brought, and what the future might hold. But this year felt different from all those that had come before. Joe and Jill Biden’s eldest son, Beau, had been diagnosed with a malignant brain tumor fifteen months earlier, and his survival was uncertain. “Promise me, Dad,” Beau had told his father. “Give me your word that no matter what happens, you’re going to be all right.” Joe Biden gave him his word.Promise Me Dad chronicles the year that followed, which would be the most momentous and challenging in Joe Biden’s extraordinary life and career. As vice president, Biden traveled more than a hundred thousand miles that year, across the world, dealing with crises in Ukraine, Central America, and Iraq. When a call came from New York, or Capitol Hill, or Kyiv, or Baghdad—“Joe, I need your help”—he responded. For twelve months, while Beau fought for and then lost his life, the vice president balanced the twin imperatives of living up to his responsibilities to his country and his responsibilities to his family. And never far away was the insistent and urgent question of whether he should seek the presidency in 2016.The year brought real triumph and accomplishment, and wrenching pain. But even in the worst times, Biden was able to lean on the strength of his long, deep bonds with his family, on his faith, and on his deepening friendship with the man in the Oval Office, Barack Obama.Writing with poignancy and immediacy, Joe Biden allows readers to feel the urgency of each moment, to experience the days when he felt unable to move forward as well as the days when he felt like he could not afford to stop.This is a book written not just by the president, but by a father, grandfather, friend, and husband. Promise Me Dad is a story of how family and friendships sustain us and how hope, purpose, and action can guide us through the pain of personal loss into the light of a new future.

    My Family and Other Animals was intended to embrace the natural history of the island but ended up as a delightful account of Durrell’s family’s experiences, from the many eccentric hangers-on to the ceaseless procession of puppies, toads, scorpions, geckoes, ladybugs, glowworms, octopuses, bats, and butterflies into their home.

    When Haregwoin Teferra’s husband and daughter died within a few years of each other, her life is shattered and she becomes a recluse. But then a priest delivers an orphan to her door. The another, and another... and together they thrive.The distinguished author of Praying for Sheetrock and two-time National Book award finalist puts a human face on the AIDS crisis in Africa. When Haregwoin Teferra’s husband and 23-year-old daughter died within a few years of each other, her middle-class life in Addis Ababa, Ethiopia, was shattered. Bereft and with little to live for, Haregwoin became a recluse. Her self-imposed exile to a hut near her daughter’s grave was interrupted when a priest delivered first one, then another, orphaned teenager into her care. To everyone’s surprise, the children thrived, and so did Haregwoin. As word spread, children of all ages began to appear at her modest home: an infant brought by a dying mother, an orphaned brother and sister whose grandfather was too poor to feed them, a baby left on her doorstep. Haregwoin’s small compound became known as the rare place where ailing parents and impoverished families could safely leave their children. Soon Haregwoin was caring for sixty children, running an unofficial orphanage and day school, and learning first-hand about her country’s and her continent’s greatest challenge: the AIDS pandemic that is leaving millions of children without parents to care for them. With the flair and grace of a novelist and the reportorial instincts of a seasoned journalist, Melissa Fay Greene gets to the heart of the AIDS crisis, in a story that is nevertheless one of hope. There Is No Me Without You is the story of Haregwoin and her children: a story of struggle and despair, but also of the triumph of saved lives, and the renewed happiness of children welcomed by adoptive parents in Ethiopia, America, and around the world. Haregewoin’s remarkable story convinces us that the crisis in Africa touches every one of us in some fundamental way. At heart, this book is about children and the parents they need to care for them.

    Over the course of two years, the impressionable teenager endured manipulation, psychological control, and physical abuse as the harsh realities and looming darkness of Charles Manson’s true nature revealed itself. From Spahn ranch and the group acid trips, to the Beatles’ White Album and Manson’s dangerous messiah-complex, Dianne tells the riveting story of the group’s descent into madness as she lived it.Though she never participated in any of the group’s gruesome crimes and was purposely insulated from them, Dianne was arrested with the rest of the Manson Family, and eventually learned enough to join the prosecution’s case against them. With the help of good Samaritans, including the cop who first arrested her and later adopted her, the courageous young woman eventually found redemption and grew up to lead an ordinary life.While much has been written about Charles Manson, this riveting account from an actual Family member is a chilling portrait that recreates in vivid detail one of the most horrifying and fascinating chapters in modern American history.Member of the Family includes 16 pages of photographs.

    It is an unprecedented family record that reveals how the painful legacy of slavery continues to endure in America's collective memory and experience. Ball, a descendant of one of the largest slave-owning families in the South, discovered that his ancestors owned 25 plantations, worked by nearly 4,000 slaves. Through meticulous research and by interviewing scattered relatives, Ball contacted some 100,000 African-Americans who are all descendants of Ball slaves. In intimate conversations with them, he garnered information, hard words, and devastating family stories of precisely what it means to be enslaved. He found that the family plantation owners were far from benevolent patriarchs; instead there is a dark history of exploitation, interbreeding, and extreme violence.

    Amaryllis Fox's memoir tells the story of her ten years in the most elite clandestine ops unit of the CIA, hunting the world's most dangerous terrorists in sixteen countries while marrying and giving birth to a daughter.

    The disintegration of this group, a process that has been slowly occurring now for more than forty years, has been reported with growing frequency and alarm, but has never before been written about as searingly from the inside. J. D. Vance tells the true story of what a social, regional, and class decline feels like when you were born with it hung around your neck.The Vance family story begins hopefully in postwar America. J. D.’s grandparents were “dirt poor and in love,” and moved north from Kentucky’s Appalachia region to Ohio in the hopes of escaping the dreadful poverty around them. They raised a middle-class family, and eventually one of their grandchildren would graduate from Yale Law School, a conventional marker of success in achieving generational upward mobility. But as the family saga of Hillbilly Elegy plays out, we learn that J.D.'s grandparents, aunt, uncle, sister, and, most of all, his mother struggled profoundly with the demands of their new middle-class life, never fully escaping the legacy of abuse, alcoholism, poverty, and trauma so characteristic of their part of America. With piercing honesty, Vance shows how he himself still carries around the demons of his chaotic family history.A deeply moving memoir, with its share of humor and vividly colorful figures, Hillbilly Elegy is the story of how upward mobility really feels. And it is an urgent and troubling meditation on the loss of the American dream for a large segment of this country.

    Trevor Noah’s unlikely path from apartheid South Africa to the desk of The Daily Show began with a criminal act: his birth. Trevor was born to a white Swiss father and a black Xhosa mother at a time when such a union was punishable by five years in prison. Living proof of his parents’ indiscretion, Trevor was kept mostly indoors for the earliest years of his life, bound by the extreme and often absurd measures his mother took to hide him from a government that could, at any moment, steal him away. Finally liberated by the end of South Africa’s tyrannical white rule, Trevor and his mother set forth on a grand adventure, living openly and freely and embracing the opportunities won by a centuries-long struggle. Born a Crime is the story of a mischievous young boy who grows into a restless young man as he struggles to find himself in a world where he was never supposed to exist. It is also the story of that young man’s relationship with his fearless, rebellious, and fervently religious mother—his teammate, a woman determined to save her son from the cycle of poverty, violence, and abuse that would ultimately threaten her own life.

    Lee embarks on a journey to discover her family's forgotten history and to connect with the island they once called home Taiwan is an island of extremes: towering mountains, lush forests, and barren escarpment. Between shifting tectonic plates and a history rife with tension, the geographical and political landscape is forever evolving. After unearthing a hidden memoir of her grandfather's life, Jessica J. Lee seeks to piece together the fragments of her family's history as they moved from China to Taiwan, and then on to Canada. But as she navigates the tumultuous terrain of Taiwan, Lee finds herself having to traverse fissures in language, memory, and history, as she searches for the pieces of her family left behind.Interlacing a personal narrative with Taiwan's history and terrain, Two Trees Make a Forest is an intimate examination of the human relationship with geography and nature, and offers an exploration of one woman's search for history and belonging amidst an ever-shifting landscape.

    The child of two lawyers, they are staunchly anti-death penalty. But the moment convicted murderer Ricky Langley’s face flashes on the screen as they review old tapes—the moment they hear him speak of his crimes -- they are overcome with the feeling of wanting him to die. Shocked by their reaction, they dig deeper and deeper into the case. Despite their vastly different circumstances, something in his story is unsettlingly, uncannily familiar.Crime, even the darkest and most unsayable acts, can happen to any one of us. As Alex pores over the facts of the murder, they find themself thrust into the complicated narrative of Ricky’s childhood. And by examining the details of Ricky’s case, they are forced to face their own story, to unearth long-buried family secrets, and reckon with a past that colors their view of Ricky's crime.But another surprise awaits: They weren’t the only one who saw their life in Ricky’s.An intellectual and emotional thriller that is also a different kind of murder mystery, THE FACT OF A BODY is a book not only about how the story of one crime was constructed -- but about how we grapple with our own personal histories. Along the way it tackles questions about the nature of forgiveness, and if a single narrative can ever really contain something as definitive as the truth. This groundbreaking, heart-stopping work, ten years in the making, shows how the law is more personal than we would like to believe -- and the truth more complicated, and powerful, than we could ever imagine.

    Every passerby was an actor; every car would magically stop for him; everything he saw was a cue from "The Producer" to help inspire the performance of a lifetime. After a manic spree around Manhattan, Zack, who is bipolar, was arrested on a subway platform and admitted to Bellevue Hospital. So begins the story of Zack's freefall into psychosis and his desperate, poignant, often darkly funny struggle to claw his way back to sanity. It's a journey that will take him from New York City back to his Kansas roots and to the one person who might be able to save him, his tough, big-hearted Midwestern mother, nicknamed the Bird, whose fierce and steadfast love is the light in Zack's dark world. Before his odyssey is over, Zack will be tackled by guards in mental wards, run naked through cornfields, receive secret messages from the TV, befriend a former Navy Seal and his talking stuffed monkey, and see the Virgin Mary in the whorls of his own back hair. But with the Bird's help, he just might have a shot at pulling through, starting over, and maybe even meeting a woman who can love him back, bipolar and all. Written with raw emotional power, humor, and tenderness, GORILLA AND THE BIRD is a bravely honest account of a young man's unraveling and the relationship that saves him.

    In her brutally honest, hilarious, heartbreaking memoir, she reveals what was going on behind the scenes of her sometimes tumultuous personal and professional life - a story she’s never shared, until now. Of the medium she loves, the one that made her a household name, she says, “Television can put you in a box; the flat-screen can flatten. On TV, you are larger than life but smaller, too. It is not the whole story, and it is not the whole me. This book is.”Beginning in early childhood, Couric was inspired by her journalist father to pursue the career he loved but couldn’t afford to stay in. Balancing her vivacious, outgoing personality with her desire to be taken seriously, she overcame every obstacle in her way: insecurity, an eating disorder, being typecast, sexism . . . challenges, and how she dealt with them, setting the tone for the rest of her career. Couric talks candidly about adjusting to sudden fame after her astonishing rise to co-anchor of the TODAY show, and guides us through the most momentous events and news stories of the era, to which she had a front-row seat:  Rodney King, Anita Hill, Columbine, the death of Princess Diana, 9/11, the Iraq War . . . In every instance, she relentlessly pursued the facts, ruffling more than a few feathers along the way.  She also recalls in vivid and sometimes lurid detail the intense pressure on female anchors to snag the latest “get”—often sensational tabloid stories like Jon Benet Ramsey, Tonya Harding, and OJ Simpson.Couric’s position as one of the leading lights of her profession was  shadowed by the shock and trauma of losing her husband to stage 4 colon cancer when he was just 42, leaving her a widow and single mom to two daughters, 6 and 2. The death of her sister Emily, just three years later, brought yet more trauma—and an unwavering commitment to cancer awareness and research, one of her proudest accomplishments. Couric is unsparing in the details of her historic move to the anchor chair at the CBS Evening News—a world rife with sexism and misogyny.  Her “welcome” was even more hostile at 60 Minutes, an unrepentant boys club that engaged in outright hazing of even the most established women.  In the wake of the MeToo movement, Couric shares her clear-eyed reckoning with gender inequality and predatory behavior in the workplace, and downfall of Matt Lauer—a colleague she had trusted and respected for more than a decade.Couric also talks about the challenge of finding love again, with all the hilarity, false-starts, and drama that search entailed, before finding her midlife Mr. Right.  Something she has never discussed publicly—why her second marriage almost didn’t happen. If you thought you knew Katie Couric, think again. Going There is the fast-paced, emotional, riveting story of a thoroughly modern woman, whose journey took her from humble origins to superstardom. In these pages, you will find a friend, a confidante, a role model, a survivor whose lessons about life will enrich your own.

    Mokhtar Alkhanshali is twenty-four and working as a doorman when he discovers the astonishing history of coffee and Yemen’s central place in it. He leaves San Francisco and travels deep into his ancestral homeland to tour terraced farms high in the country’s rugged mountains and meet beleagured but determined farmers. But when war engulfs the country and Saudi bombs rain down, Mokhtar has to find a way out of Yemen without sacrificing his dreams or abandoning his people.

    It's odd when I think of the arc of my life, from child to young woman to aging adult. First I was who I was. Then I didn't know who I was. Then I invented someone, and became her. Then I began to like what I'd invented. And finally I was what I was again. It turned out I wasn't alone in that particular progression. As she did in her beloved New York Times columns, and in A Short Guide to a Happy Life, Quindlen says for us here what we may wish we could have said ourselves. Using her past, present, and future to explore what matters most to women at different ages, Quindlen talks aboutMarriage: "A safety net of small white lies can be the bedrock of a successful marriage. You wouldn't believe how cheaply I can do a kitchen renovation."Girlfriends: "Real friends offer both hard truths and soft landings and realize that it's sometimes more important to be nice than to be honest." Our bodies: "I've finally recognized my body for what it is, a personality-delivery system, designed expressly to carry my character from place to place, now and in the years to come. It's like a car, and while I like a red convertible or even a Bentley as well as the next person, what I really need are four tires and an engine."Parenting: "Being a parent is not transactional. We do not get what we give. It is the ultimate pay-it-forward: We are good parents, not so they will be loving enough to stay with us, but so they will be strong enough to leave us." From childhood memories to manic motherhood to middle age, Quindlen uses the events of her own life to illuminate our own. Along with the downsides of age, she says, can come wisdom, a perspective on life that makes it both satisfying and even joyful. So here's to lots of candles, plenty of cake.