In Under the Knife, surgeon Arnold Van de Laar uses his own experience and expertise to tell the witty history of the past, present and future of surgery.From the story of the desperate man from seventeenth-century Amsterdam who grimly cut a stone out of his own bladder to Bob Marley's deadly toe, Under the Knife offers all kinds of fascinating and unforgettable insights into medicine and history via the operating theatre.What happens during an operation? How does the human body respond to being attacked by a knife, a bacterium, a cancer cell or a bullet? And, as medical advances continuously push the boundaries of what medicine can cure, what are the limits of surgery?From the dark centuries of bloodletting and of amputations without anaesthetic to today's sterile, high-tech operating theatres, Under the Knife is both a rich cultural history, and a modern anatomy class for us all.

    Barbara Ravage has fashioned an enlightening, invaluable book.” —Stewart O’Nan, author of The Circus Fire: A True Story of an American TragedyThough each of us is just a spark away from being a burn victim, the public knows little and understands less about the world that patients inhabit. Pulling the curtains back on this private and sterile environment, Burn Unit is a riveting account of the frontline efforts—both modern-day and historical—to save lives devastated by fire. With unflinching urgency, Barbara Ravage follows an extraordinary team of healers at Massachusetts General Hospital, the cradle of modern burn treatment and the site of one of the best burn units in the world. From Boston’s Cocoanut Grove fire of 1942 to the treatment of the victims of the Rhode Island nightclub fire in early 2003, we watch everyday heroes do their incredible but punishing work against the backdrop of history. Both a moving human drama and an engrossing scientific exploration of this little-known field of medicine, Burn Unit is an unforgettably powerful read.

    But for thousands of years, people have done things like this—and things that make radioactive underpants seem downright sensible! In their hit podcast, Sawbones, Sydnee and Justin McElroy breakdown the weird and wonderful way we got to modern healthcare. And some of the terrifying detours along the way.Every week, Dr. Sydnee McElroy and her husband Justin amaze, amuse, and gross out (depending on the week) hundreds of thousands of avid listeners to their podcast, Sawbones. Consistently rated a top podcast on iTunes, with over 15 million total downloads, this rollicking journey through thousands of years of medical mishaps and miracles is not only hilarious but downright educational. While you may never even consider applying  boiled weasel to your forehead (once the height of sophistication when it came to headache cures), you will almost certainly face some questionable medical advice in your everyday life (we’re looking at you, raw water!) and be better able to figure out if this is a miracle cure (it’s not) or a scam. Table of Contents:Part One: The Unnerving The Resurrection Men Fun w Galvanism Weird Weight Loss Miracle Cure: Opium Black Plague Heroes of Misguided Medicine: Pliny the Elder Erectile Dysfunction The Doctor Is In: Listener Questions Answered Don’t Drill a Hole in Your HeadPart Two: The Gross Mummy Medicine The Guthole Bromance The Unkillable Phineas Gage Max Drank Poopy Water Heroes of Misguided Medicine: Robert Liston Golden Showers of Health Miracle Cure-All: Radium Dr. John Romulus Brinkley The Doctor Is In Q&A Just (Four) Humour Me The Camel Dung MiraclePart Three: The Weird The Dancing Plague Bad Medicine: Tobacco for Health The Seasick-Proof Saloon Miracle Cure-All: Vinegar The Doctor Is In Q&A Heroes of Misguided MedicinePart Four: The Awesome The Poison Squad Bad Medicine: Self Experimentation Eat Your Chocolate! Heroes of Misguided Medicine Parrot Fever Miracle Cure-All: Honey The Miraculous Polio Vaccine The Doctor Is In

    Our bodies are hardwired for sweets, so food giants have developed fifty-six types of sugar to add to their products, creating in us the expectation that everything should be cloying; we've evolved to prefer fast, convenient meals, hence our modern-day preference for ready-to-eat foods. Moss goes on to show how the processed food industry--including major companies like Nestlé, Mars, and Kellogg's--has tried not only to evade this troubling discovery about the addictiveness of food but to actually exploit it. For instance, in response to recent dieting trends, food manufacturers have simply turned junk food into junk diets, filling grocery stores with "diet" foods that are hardly distinguishable from the products that got us into trouble in the first place. As obesity rates continue to climb, manufacturers are now claiming to add ingredients that can effortlessly cure our compulsive eating habits. An account of the legal battles, insidious marketing campaigns, and cutting-edge food science that have brought us to our current public health crisis, Moss lays out all that the food industry is doing to exploit and deepen our addictions, and shows us why what we eat has never mattered more.From the #1 New York Times bestselling author of Salt Sugar Fat comes a powerful exposé of how the processed food industry exploits our evolutionary instincts, the emotions we associate with food, and legal loopholes in their pursuit of profit over public health.

    Gifted Hands will transplace you into the operating room to witness surgeries that made headlines around the world, and into the private mind of a compassionate, God-fearing physician who lives to help others. In 1987, Dr. Carson gained worldwide recognition for his part in the first successful separation of Siamese twins joined at the back of the head -- an extremely complex and delicate operation that was five months of planning and twenty-two hours of actual surgery, involving a surgical plan that Carson helped initiate. Gifted Hands reveals a man with humility, decency, compassion, courage, and sensitivity who serves as a role model for young people (and everyone else) in need of encouragement to attempt the seemingly impossible and to excel in whatever they attempt. Dr. Carson also describes the key role that his highly intelligent though relatively uneducated mother played in his metamorphosis from an unmotivated ghetto youngster into one of the most respected neurosurgeons in the world.

    Sapolsky's storytelling concept is delightful but it also has a powerful intrinsic logic: he starts by looking at the factors that bear on a person's reaction in the precise moment a behavior occurs, and then hops back in time from there, in stages, ultimately ending up at the deep history of our species and its evolutionary legacy.And so the first category of explanation is the neurobiological one. A behavior occurs--whether an example of humans at our best, worst, or somewhere in between. What went on in a person's brain a second before the behavior happened? Then Sapolsky pulls out to a slightly larger field of vision, a little earlier in time: What sight, sound, or smell caused the nervous system to produce that behavior? And then, what hormones acted hours to days earlier to change how responsive that individual is to the stimuli that triggered the nervous system? By now he has increased our field of vision so that we are thinking about neurobiology and the sensory world of our environment and endocrinology in trying to explain what happened.Sapolsky keeps going: How was that behavior influenced by structural changes in the nervous system over the preceding months, by that person's adolescence, childhood, fetal life, and then back to his or her genetic makeup? Finally, he expands the view to encompass factors larger than one individual. How did culture shape that individual's group, what ecological factors millennia old formed that culture? And on and on, back to evolutionary factors millions of years old.The result is one of the most dazzling tours d'horizon of the science of human behavior ever attempted, a majestic synthesis that harvests cutting-edge research across a range of disciplines to provide a subtle and nuanced perspective on why we ultimately do the things we do...for good and for ill. Sapolsky builds on this understanding to wrestle with some of our deepest and thorniest questions relating to tribalism and xenophobia, hierarchy and competition, morality and free will, and war and peace. Wise, humane, often very funny, Behave is a towering achievement, powerfully humanizing, and downright heroic in its own right.

    Dr. Jeremy Brown, currently Director of Emergency Care Research at the National Institutes of Health, expounds on the flu's deadly past to solve the mysteries that could protect us from the next outbreak. In Influenza, he talks with leading epidemiologists, policy makers, and the researcher who first sequenced the genetic building blocks of the original 1918 virus to offer both a comprehensive history and a roadmap for understanding what’s to come.Dr. Brown digs into the discovery and resurrection of the flu virus in the frozen victims of the 1918 epidemic, as well as the bizarre remedies that once treated the disease, such as whiskey and blood-letting. Influenza also breaks down the current dialogue surrounding the disease, explaining the controversy over vaccinations, antiviral drugs like Tamiflu, and the federal government’s role in preparing for pandemic outbreaks. Though 100 years of advancement in medical research and technology have passed since the 1918 disaster, Dr. Brown warns that many of the most vital questions about the flu virus continue to confound even the leading experts.Influenza is an enlightening and unnerving look at a shapeshifting deadly virus that has been around long before people—and warns us that it may be many more years before we are able to conquer it for good.

    But the so-called Dark Ages also gave us the first universities, eyeglasses, and mechanical clocks, proving that the Middle Ages were home to a vibrant scientific culture.In The Light Ages, Cambridge science historian Seb Falk takes us on an immersive tour of medieval science through the story of one fourteenth-century monk, John of Westwyk. From multiplying Roman numerals to navigating by the stars, curing disease, and telling time with an ancient astrolabe, we learn emerging science alongside Westwyk, while following the gripping story of the struggles and successes of an ordinary man in a precarious world. An enlightening history that argues that these times weren’t so dark after all, The Light Ages shows how medieval ideas continue to color how we see the world today.

    With humor and insight, Melissa Mohr takes readers on a journey to discover how "swearing" has come to include both testifying with your hand on the Bible and calling someone a *#$&!* when they cut you off on the highway. She explores obscenities in ancient Rome and unearths the history of religious oaths in the Middle Ages, when swearing (or not swearing) an oath was often a matter of life and death. Holy Sh*t also explains the advancement of civility and corresponding censorship of language in the 18th century, considers the rise of racial slurs after World War II, examines the physiological effects of swearing and answers a question that preoccupies the FCC, the US Senate, and anyone who has recently overheard little kids at a playground: are we swearing more now than people did in the past?A gem of lexicography and cultural history, Holy Sh*t is a serious exploration of obscenity.

    The lifesaving serum was a thousand miles away, the port was icebound, and planes couldn't fly in blizzard conditions—only the dogs could make it. The heroic dash of dog teams across the Alaskan wilderness to Nome inspired the annual Iditarod Trail Sled Dog Race and immortalized Balto, the lead dog of the last team whose bronze statue still stands in New York City's Central Park. This is the greatest dog story, never fully told until now.

    Why does half a conversation make us more curious than a whole conversation? In the ever-fascinating Why? Mario Livio interviewed scientists in several fields to explore the nature of curiosity. He examined the lives of two of history’s most curious geniuses, Leonardo da Vinci and Richard Feynman. He also talked to people with boundless curiosity: a superstar rock guitarist who is also an astrophysicist; an astronaut with degrees in computer science, biology, literature, and medicine. What drives these people to be curious about so many subjects? Curiosity is at the heart of mystery and suspense novels. It is essential to other forms of art, from painting to sculpture to music. It is the principal driver of basic scientific research. Even so, there is still no definitive scientific consensus about why we humans are so curious, or about the mechanisms in our brain that are responsible for curiosity. Mario Livio—an astrophysicist who has written about mathematics, biology, and now psychology and neuroscience—explores this irresistible subject in a lucid, entertaining way that will captivate anyone who is curious about curiosity.

    But this attitude is a relatively recent development in the sweep of history. In The Pun Also Rises, John Pollack — a former Presidential Speechwriter for Bill Clinton, and winner of the world pun championship — explains how punning revolutionized language and made possible the rise of modern civilization. Integrating evidence from history, pop culture, literature, comedy, science, business and everyday life, this book will make readers reconsider everything they think they know about puns.

    . . when it comes to the legacy of this country's war on drugs, we should all share his outrage." --The New York Times Book Review From one of the world's foremost experts on the subject, a powerful argument that the greatest damage from drugs flows from their being illegal, and a hopeful reckoning with the possibility of their use as part of a responsible and happy lifeDr. Carl L. Hart, Ziff Professor at Columbia University and former chair of the Department of Psychology, is one of the world's preeminent experts on the effects of so-called recreational drugs on the human mind and body. Dr. Hart is open about the fact that he uses drugs himself, in a happy balance with the rest of his full and productive life as a colleague, husband, father, and friend. In Drug Use for Grown-Ups, he draws on decades of research and his own personal experience to argue definitively that the criminalization and demonization of drug use--not drugs themselves--have been a tremendous scourge on America, not least in reinforcing this country's enduring structural racism.Dr. Hart did not always have this view. He came of age in one of Miami's most troubled neighborhoods at a time when many ills were being laid at the door of crack cocaine. His initial work as a researcher was aimed at proving that drug use caused bad outcomes. But one problem kept cropping up: the evidence from his research did not support his hypothesis. From inside the massively well-funded research arm of the American war on drugs, he saw how the facts did not support the ideology. The truth was dismissed and distorted in order to keep fear and outrage stoked, the funds rolling in, and Black and brown bodies behind bars.Drug Use for Grown-Ups will be controversial, to be sure: the propaganda war, Dr. Hart argues, has been tremendously effective. Imagine if the only subject of any discussion about driving automobiles was fatal car crashes. Drug Use for Grown-Ups offers a radically different vision: when used responsibly, drugs can enrich and enhance our lives. We have a long way to go, but the vital conversation this book will generate is an extraordinarily important step.

    Now updated with new material that brings the killer's picture into clearer focus.In the fall of 1888, all of London was held in the grip of unspeakable terror.  An elusive madman calling himself Jack the Ripper was brutally butchering women in the slums of London’s East End.  Police seemed powerless to stop the killer, who delighted in taunting them and whose crimes were clearly escalating in violence from victim to victim.  And then the Ripper’s violent spree seemingly ended as abruptly as it had begun.  He had struck out of nowhere and then vanished from the scene.  Decades passed, then fifty years, then a hundred, and the Ripper’s bloody sexual crimes became anemic and impotent fodder for puzzles, mystery weekends, crime conventions, and so-called “Ripper Walks” that end with pints of ale in the pubs of Whitechapel.  But to number-one New York Times bestselling novelist Patricia Cornwell, the Ripper murders are not cute little mysteries to be transformed into parlor games or movies but rather a series of terrible crimes that no one should get away with, even after death.  Now Cornwell applies her trademark skills for meticulous research and scientific expertise to dig deeper into the Ripper case than any detective before her—and reveal the true identity of this fabled Victorian killer.In Portrait of a Killer: Jack the Ripper, Case Closed, Cornwell combines the rigorous discipline of twenty-first century police investigation with forensic techniques undreamed of during the late Victorian era to solve one of the most infamous and difficult serial murder cases in history.  Drawing on unparalleled access to original Ripper evidence, documents, and records, as well as archival, academic, and law-enforcement resources, FBI profilers, and top forensic scientists, Cornwell reveals that Jack the Ripper was none other than a respected painter of his day, an artist now collected by some of the world’s finest museums: Walter Richard Sickert.It has been said of Cornwell that no one depicts the human capability for evil better than she.   Adding layer after layer of circumstantial evidence to the physical evidence discovered by modern forensic science and expert minds, Cornwell shows that Sickert, who died peacefully in his bed in 1942, at the age of 81, was not only one of Great Britain’s greatest painters but also a serial killer, a damaged diabolical man driven by megalomania and hate.  She exposes Sickert as the author of the infamous Ripper letters that were written to the Metropolitan Police and the press.  Her detailed analysis of his paintings shows that his art continually depicted his horrific mutilation of his victims, and her examination of this man’s birth defects, the consequent genital surgical interventions, and their effects on his upbringing present a casebook example of how a psychopathic killer is created.New information and startling revelations detailed in Portrait of a Killer include:- How a year-long battery of more than 100 DNA tests—on samples drawn by Cornwell’s forensics team in September 2001 from original Ripper letters and Sickert documents—yielded the first shadows of the 75- to 114 year-old genetic evid...

    This collection reveals some of the most chilling, captivating, and weird cases that Richard has investigated over the past twenty years, in England and in the United States.In Search of the Paranormal is filled with rich historical detail, present-day research, and compelling eyewitness accounts. You are there with the team at each haunted location: walking through a desecrated graveyard, shivering in a dark basement, getting thrown into The Clink, watching a ghost-lit stage in an old theater. Employing a variety of investigative methods--from high-tech gadgets to old-fashioned practices such as dowsing, table tipping, and Ouija boards--Richard Estep and his team uncover the dark mysteries of the paranormal realm.Praise: This book is written from the heart. Believe in the paranormal or not, Richard Estep's words ring out with sincerity and integrity.--Patrick Burns, star of Haunting EvidenceWithin these pages, you can join Richard on his ghostly adventures, from the UK to the US and experience with him what it's like to be a Paranormal Investigator.--Paul Bradford, star of Ghost Hunters International