She was a poor Southern tobacco farmer who worked the same land as her enslaved ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine. The first “immortal” human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they’d weigh more than 50 million metric tons—as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions.Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.Now Rebecca Skloot takes us on an extraordinary journey, from the “colored” ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta’s small, dying hometown of Clover, Virginia — a land of wooden quarters for enslaved people, faith healings, and voodoo — to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells.Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family — past and present — is inextricably connected to the history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of.Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah, who was devastated to learn about her mother’s cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn’t her children afford health insurance?Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.

    In this compelling memoir, his first wife, Jane Hawking, relates the inside story of their extraordinary marriage. As Stephen's academic renown soared, his body was collapsing under the assaults of a motor neuron disease. Jane's candid account of trying to balance his 24-hour care with the needs of their growing family reveals the inner strength of the author, while the self-evident character and achievements of her husband make for an incredible tale presented with unflinching honesty. Jane's candor is no less apparent when the marriage finally ends in a high-profile meltdown, with Stephen leaving Jane for one of his nurses and Jane marrying an old family friend. In this exceptionally open, moving, and often funny memoir, Jane Hawking confronts not only the acutely complicated and painful dilemmas of her first marriage, but also the relationship's fault lines exposed by the pervasive effects of fame and wealth. The result is a book about optimism, love, and change that will resonate with readers everywhere.

    Clark's clear-eyed sympathy for Hughes, his lover Assia Wevill, and other demonized players in the arena of Plath's suicide promotes a deeper understanding of her final days, with their outpouring of first-rate poems. Along with illuminating readings of the poems themselves, Clark's meticulous, compassionate research brings us closer than ever to the spirited woman and visionary artist who blazed a trail that still lights the way for women poets the world over.

    That book was the last surviving manuscript of an ancient Roman philosophical epic, On the Nature of Things, by Lucretius—a beautiful poem of the most dangerous ideas: that the universe functioned without the aid of gods, that religious fear was damaging to human life, and that matter was made up of very small particles in eternal motion, colliding and swerving in new directions.The copying and translation of this ancient book—the greatest discovery of the greatest book-hunter of his age—fueled the Renaissance, inspiring artists such as Botticelli and thinkers such as Giordano Bruno; shaped the thought of Galileo and Freud, Darwin and Einstein; and had a revolutionary influence on writers such as Montaigne and Shakespeare and even Thomas Jefferson.

    You learn the points of view your teachers provide, the perspectives that books offer, and the conclusions you draw yourself based on the facts you were given. Hearing different angles on historical events gives you a more insightful, more accurate, and more rewarding understanding of events – especially when a new viewpoint challenges the story you thought you knew.

    But is this image really accurate?Recent scholarship examining the Persian Empire from the Persian perspective has discovered a major force that has had a lasting influence on the world in terms of administration, economics, religion, architecture, and more. In fact, the Persian Empire was arguably the world's first global power—a diverse, multicultural empire with flourishing businesses and people on the move. It was an empire of information, made possible by a highly advanced infrastructure that included roads, canals, bridges, and a courier system. And the kings of Persia's Achaemenid dynasty —Cyrus, Darius, Xerxes, and others—presided over an empire that created a tremendous legacy for subsequent history.The Persian Empire is your opportunity to see one of the greatest empires in the ancient world from a fresh new perspective: its own. Over the span of 24 fascinating lectures, Professor John W. I. Lee of the University of California, Santa Barbara—a distinguished teacher and an expert on the long-buried secrets of the ancient world—takes the role of a history detective and examines Persian sources to reveal what we now know about this grand civilization. Tapping into the latest scholarship on the Persian Empire, this course is sure to fill in some critical gaps in your understanding and appreciation of the sweep of ancient history and its undeniable effect on later civilizations—including our own.

    Three young friends meet over apricot cocktails at the Bec-de-Gaz bar on the rue Montparnasse. They are Jean-Paul Sartre, Simone de Beauvoir and their friend Raymond Aron, who opens their eyes to a radical new way of thinking. Pointing to his drink, he says, 'You can make philosophy out of this cocktail!'From this moment of inspiration, Sartre will create his own extraordinary philosophy of real, experienced life–of love and desire, of freedom and being, of cafés and waiters, of friendships and revolutionary fervour. It is a philosophy that will enthral Paris and sweep through the world, leaving its mark on post-war liberation movements, from the student uprisings of 1968 to civil rights pioneers.At the Existentialist Café tells the story of modern existentialism as one of passionate encounters between people, minds and ideas. From the ‘king and queen of existentialism'–Sartre and de Beauvoir–to their wider circle of friends and adversaries including Albert Camus, Martin Heidegger, Maurice Merleau-Ponty and Iris Murdoch, this book is an enjoyable and original journey through a captivating intellectual movement. Weaving biography and thought, Sarah Bakewell takes us to the heart of a philosophy about life that also changed lives, and that tackled the biggest questions of all: what we are and how we are to live.

    Bread, cash, dosh, dough, loot, lucre, moolah, readies, the wherewithal: Call it what you like, it matters. To Christians, love of it is the root of all evil. To generals, it’s the sinews of war. To revolutionaries, it’s the chains of labor. But in The Ascent of Money, Niall Ferguson shows that finance is in fact the foundation of human progress. What’s more, he reveals financial history as the essential backstory behind all history. With the clarity and verve for which he is known, Ferguson elucidates key financial institutions and concepts by showing where they came from. What is money? What do banks do? What’s the difference between a stock and a bond? Why buy insurance or real estate? And what exactly does a hedge fund do? This is history for the present. Ferguson travels to post-Katrina New Orleans to ask why the free market can’t provide adequate protection against catastrophe. He delves into the origins of the subprime mortgage crisis.

    Assigned by Louis XIV, Nicolas de La Reynie begins by clearing the streets of filth, and installing lanterns throughout Paris, turning it into the City of Light.The fearless La Reynie pursues criminals through the labyrinthine neighborhoods of the city. He unearths a tightly knit cabal of poisoners, witches, and renegade priests. As he exposes their unholy work, he soon learns that no one is safe from black magic - not even the Sun King. In a world where a royal glance can turn success into disgrace, the distance between the quietly back-stabbing world of the king’s court, and the criminal underground proves disturbingly short. Nobles settle scores by employing witches to craft poisons, and by hiring priests to perform dark rituals in Paris' most illustrious churches and cathedrals.As La Reynie continues his investigations, he is haunted by a single question: Could Louis’ mistresses be involved in such nefarious plots? The pragmatic, and principled, La Reynie must decide just how far he will go to protect his king.From secret courtrooms to torture chambers, City of Light, City of Poison is a gripping true-crime tale of deception and murder. Based on thousands of pages of court transcripts, and La Reynie’s compulsive note-taking, as well as on letters and diaries, Tucker’s riveting narrative makes the fascinating, real-life characters breathe on the page.

    Every night we surrender it gratefully, only to get it back in the morning. We recognize that we have it, but we can never be sure anyone else does. Consciousness, this unique and perplexing mental state, has been the subject of debate for philosophers and scientists for millennia. And while it is widely agreed within contemporary philosophy that consciousness is a problem whose solutions are likely to determine the fate of any number of other problems, there is no settled position on the ultimate nature of consciousness.What is the most promising way to study this subject? What are the implications that arise from the fact that we have consciousness? What are the ethical and moral issues raised by its presence—or its absence? Questions like these are at the heart of Consciousness and Its Implications, 12 thought-provoking lectures delivered by distinguished philosopher and psychologist Daniel N. Robinson. Rather than merely explain away consciousness, or hide behind such convenient slogans as "it's all in your brain," Professor Robinson reviews some of the special problems that philosophers, psychologists, scientists, and doctors face when taking on such a vexing topic.What Is Consciousness? Much of what we do every day is done without our being directly conscious of the steps taken to complete the task: riding a bicycle, taking a walk, humming a tune. But as natural as this state is, it stands as a very serious threat to any number of core convictions and assumptions in both philosophy and science. One of the overarching goals of this intriguing course is to make clear just what about consciousness serves as such a challenge to these convictions and assumptions.But what makes Consciousness and Its Implications so engaging is more than just the nature of the questions it poses and the issues it tackles. It's the way in which Professor Robinson, the consummate teacher and scholar, conveys this goal in four main points, each of which you explore in depth in these lectures.Consciousness seems to require, for its full understanding, a science not yet available. What distinguishes consciousness from all else is its phenomenology—that is, the act of being conscious is different from all other facts of nature. Conscious awareness is a power that, at times, can be so strong as to greatly affect our senses. The powers of consciousness vary over the course of a lifetime; as such, they can become subject to disease and defect.Throughout the course, Professor Robinson brings this riveting topic vividly to life with real-world examples and striking anecdotes. Review the case of Deep Blue, the IBM computer that in 1997 shocked the world by defeating a human, the chess grand master Garry Kasparov. Does Deep Blue's ability to "outsmart" a human being constitute a kind of consciousness? Or is it a reflection of the human minds that created this complex computer? Consider the case of the sleepwalker, who moves around with purpose and mimics behaviors we see in everyday life, but can remember nothing upon awakening. How does this mental state relate to human consciousness? What would be lost if we lived our entire lives as sleepwalkers?Study the case of a comatose patient who lives in an unbroken sleep state but, after a miraculous recovery, recalls having heard doctors speak about her. How do we interpret this patient's ability to perceive the surrounding world while in a coma? Does the patient's experience reflect some in-between mental state we've yet to define? Look at the case of a child with autism who can perform complicated mental tasks but lacks the most basic human attribute: empathy. How does this inability to imagine other minds affect the child's capacity to enjoy the full experience of human consciousness? Using compelling examples such as these, Professor Robinson weaves a riveting tale of the human condition that will change the way you think about your own mind.Professor Robinson also draws on the wisdom of the world's greatest thinkers—from the ancient Greeks to today's top scientists—to shed light on some of the ethical debates involved in any examination of consciousness. These include John Locke, whose famous "Prince and the Cobbler" hypothesis raised questions about the relationship between one's personal identity and one's body; Ludwig Wittgenstein, whose "Beetle in a Box" scenario holds implications for how we define consciousness both inside and outside ourselves; and Aristotle, who led a pointed discussion on the relationship between the physical world and what he referred to as "real being."You also enter the lab and explore the impact of modern physics and medicine on our understanding of the self. Pondering questions ranging from the most fundamental—"Why are we here?"—to contemporary quandaries about artificial intelligence and the medical decision to prolong life, you'll gain new insights into the complexity of how great minds define consciousness.Consciousness and Its Implications is a chance for you to view this deep and profound subject from all angles. A distinguished scholar in philosophy and neuropsychology, Professor Robinson incorporates many disciplines—psychology, physics, philosophy, medicine—to explore these abiding questions. So embark on a challenging and wholly satisfying exploration of this unique, mysterious, and essential mental faculty. The knowledge you'll gain in this course is not only intriguing—it is crucial to understanding the nature of humanity and the social and ethical obligations that define us all.

    The tycoon had close ties to the U.S. government, and he soon asked Elizebeth to apply her language skills to an exciting new venture: code-breaking. There she met the man who would become her husband, groundbreaking cryptologist William Friedman. In The Woman Who Smashed Codes, Jason Fagone chronicles the life of Elizebeth Smith who played an integral role in our nation's history for forty years. After World War I, Smith used her talents to catch gangsters and smugglers during Prohibition, then accepted a covert mission to discover and expose Nazi spy rings that were spreading like wildfire across South America, advancing ever closer to the United States. As World War II raged, Elizebeth fought a highly classified battle of wits against Hitler's Reich, cracking multiple versions of the Enigma machine used by German spies. Meanwhile, inside an Army vault in Washington, William worked furiously to break Purple, the Japanese version of Enigma--and eventually succeeded, at a terrible cost to his personal life.Fagone unveils America's code-breaking history through the prism of Smith's life, bringing into focus the unforgettable events and colorful personalities that would help shape modern intelligence.

    Rather, they recruited an elite group of young women who, with only pencil, paper, and mathematical prowess, transformed rocket design, helped bring about the first American satellites, and made the exploration of the solar system possible. For the first time, Rise of the Rocket Girls tells the stories of these women--known as "human computers"--who broke the boundaries of both gender and science. Based on extensive research and interviews with all the living members of the team, Rise of the Rocket Girls offers a unique perspective on the role of women in science: both where we've been, and the far reaches of space to which we're heading.

    She conjures up early operating theaters--no place for the squeamish--and surgeons, working before anesthesia, who were lauded for their speed and brute strength. These medical pioneers knew that the aftermath of surgery was often more dangerous than their patients' afflictions, and they were baffled by the persistent infections that kept mortality rates stubbornly high. At a time when surgery couldn't have been more hazardous, an unlikely figure stepped forward: a young, melancholy Quaker surgeon named Joseph Lister, who would solve the deadly riddle and change the course of history.Fitzharris dramatically recounts Lister's discoveries in gripping detail, culminating in his audacious claim that germs were the source of all infection--and could be countered by antiseptics. Focusing on the tumultuous period from 1850 to 1875, she introduces us to Lister and his contemporaries--some of them brilliant, some outright criminal--and takes us through the grimy medical schools and dreary hospitals where they learned their art, the deadhouses where they studied anatomy, and the graveyards they occasionally ransacked for cadavers.Eerie and illuminating, The Butchering Art celebrates the triumph of a visionary surgeon whose quest to unite science and medicine delivered us into the modern world.

    Susan Wise Bauer provides both sweeping scope and vivid attention to the individual lives that give flesh to abstract assertions about human history. Dozens of maps provide a clear geography of great events, while timelines give the reader an ongoing sense of the passage of years and cultural interconnection. This narrative history employs the methods of “history from beneath”—literature, epic traditions, private letters and accounts—to connect kings and leaders with the lives of those they ruled. The result is an engrossing tapestry of human behavior from which we may draw conclusions about the direction of world events and the causes behind them.

    In the seventy thousand years that modern human beings have walked this earth, we've come a long way. Art, science, culture, trade - on the evolutionary food chain, we're real winners. But, frankly, it's not exactly been plain sailing, and sometimes - just occasionally - we've managed to really, truly, quite unbelievably f*ck things up.From Chairman Mao's Four Pests Campaign, to the American Dustbowl; from the Austrian army attacking itself one drunken night, to the world's leading superpower electing a reality TV mogul as President... it's pretty safe to say that, as a species, we haven't exactly grown wiser with age. So, next time you think you've really f*cked up, this book will remind you: it could be so much worse