She explores the culture of genealogy buffs, the science of DNA, and the business of companies like Ancestry and 23andMe, all while tracing the story of one woman, her unusual results, and a relentless methodical drive for answers that becomes a thoroughly modern genetic detective story.

    Considered a prodigy in scientific research, he surprised everyone and himself by setting his sights on the competitive world of high finance. Yet no sooner had he landed an entry-level position at a prestigious firm than Gardner found himself caught in a web of incredibly challenging circumstances that left him as part of the city's working homeless and with a toddler son. Motivated by the promise he made to himself as a fatherless child to never abandon his own children, the two spent almost a year moving among shelters, "HO-tels," soup lines, and even sleeping in the public restroom of a subway station.Never giving in to despair, Gardner made an astonishing transformation from being part of the city's invisible poor to being a powerful player in its financial district.More than a memoir of Gardner's financial success, this is the story of a man who breaks his own family's cycle of men abandoning their children. Mythic, triumphant, and unstintingly honest, The Pursuit of Happyness conjures heroes like Horatio Alger and Antwone Fisher, and appeals to the very essence of the American Dream.

    What happened during those blackouts has made Sybil's experience one of the most famous psychological cases in the world.

    In this narrative, Walter Isaacson explains how his mind worked and the mysteries of the universe that he discovered.

    But Cullen was no mercy killer, nor was he a simple monster. He was a favorite son, husband, beloved father, best friend, and celebrated caregiver. Implicated in the deaths of as many as 300 patients, he was also perhaps the most prolific serial killer in American history.Cullen's murderous career in the world's most trusted profession spanned sixteen years and nine hospitals across New Jersey and Pennsylvania. When, in March of 2006, Charles Cullen was marched from his final sentencing in an Allentown, Pennsylvania, courthouse into a waiting police van, it seemed certain that the chilling secrets of his life, career, and capture would disappear with him. Now, in a riveting piece of investigative journalism nearly ten years in the making, journalist Charles Graeber presents the whole story for the first time. Based on hundreds of pages of previously unseen police records, interviews, wire-tap recordings and videotapes, as well as exclusive jailhouse conversations with Cullen himself and the confidential informant who helped bring him down, THE GOOD NURSE weaves an urgent, terrifying tale of murder, friendship, and betrayal.Graeber's portrait of Cullen depicts a surprisingly intelligent and complicated young man whose promising career was overwhelmed by his compulsion to kill, and whose shy demeanor masked a twisted interior life hidden even to his family and friends. Were it not for the hardboiled, unrelenting work of two former Newark homicide detectives racing to put together the pieces of Cullen's professional past, and a fellow nurse willing to put everything at risk, including her job and the safety of her children, there's no telling how many more lives could have been lost.In the tradition of In Cold Blood, THE GOOD NURSE does more than chronicle Cullen's deadly career and the breathless efforts to stop him; it paints an incredibly vivid portrait of madness and offers a penetrating look inside America's medical system. Harrowing and irresistibly paced, this book will make you look at medicine, hospitals, and the people who work in them, in an entirely different way.

    Shameful to talk about and often misunderstood, loneliness is everywhere, from the most major of metropolises to the smallest of towns.In Seek You, Kristen Radtke's wide-ranging exploration of our inner lives and public selves, Radtke digs into the ways in which we attempt to feel closer to one another, and the distance that remains. Through the lenses of gender and violence, technology and art, Radtke ushers us through a history of loneliness and longing, and shares what feels impossible to share.Ranging from the invention of the laugh-track to the rise of Instagram, the bootstrap-pulling cowboy to the brutal experiments of Harry Harlow, Radtke investigates why we engage with each other, and what we risk when we turn away. With her distinctive, emotionally charged drawings and deeply empathetic prose, Kristen Radtke masterfully shines a light on some of our most vulnerable and sublime moments, and asks how we might keep the spaces between us from splitting entirely.

    The anguished and volatile intensity associated with the artistic temperament was once thought to be a symptom of genius or eccentricity peculiar to artists, writers, and musicians. Her work, based on her study as a clinical psychologist and researcher in mood disorders, reveals that many artists subject to exalted highs and despairing lows were in fact engaged in a struggle with clinically identifiable manic-depressive illness. Jamison presents proof of the biological foundations of this disease and applies what is known about the illness to the lives and works of some of the world's greatest artists including Lord Byron, Vincent Van Gogh, and Virginia Woolf.

    By demystifying the fantasies surrounding cancer, Sontag shows cancer for what it is - just a disease. Cancer, she argues, is not a curse, not a punishment, certainly not an embarrassment and, it is highly curable, if good treatment is followed. Almost a decade later, with the outbreak of a new, stigmatized disease replete with mystifications and punitive metaphors, Sontag wrote a sequel to Illness as Metaphor, extending the argument of the earlier book to the AIDS pandemic.These two essays now published together, Illness as Metaphor and AIDS and Its Metaphors, have been translated into many languages and continue to have an enormous influence on the thinking of medical professionals and, above all, on the lives of many thousands of patients and caregivers.

    Helen Morrison has profiled more than eighty serial killers around the world. What she learned about them will shatter every assumption you've ever had about the most notorious criminals known to man.Judging by appearances, Dr. Helen Morrison has an ordinary life in the suburbs of a major city. She has a physician husband, two children, and a thriving psychiatric clinic. But her life is much more than that. She is one of the country's leading experts on serial killers, and has spent as many as four hundred hours alone in a room with depraved murderers, digging deep into killers' psyches in ways no profiler before ever has.In My Life Among the Serial Killers, Dr. Morrison relates how she profiled the Mad Biter, Richard Otto Macek, who chewed on his victims' body parts, stalked Dr. Morrison, then believed she was his wife. She did the last interview with Ed Gein, who was the inspiration for Alfred Hitchcock's Psycho. John Wayne Gacy, the clown-obsessed killer of young men, sent her crazed Christmas cards and gave her his paintings as presents. Then there was Atlanta child killer Wayne Williams; rapist turned murderer Bobby Joe Long; England's Fred and Rosemary West, who killed girls and women in their "House of Horrors"; and Brazil's deadliest killer of children, Marcelo Costa de Andrade.Dr. Morrison has received hundreds of letters from killers, read their diaries and journals, evaluated crime scenes, testified at their trials, and studied photos of the gruesome carnage. She has interviewed the families of the victims -- and the spouses and parents of the killers -- to gain a deeper understanding of the killer's environment and the public persona he adopts. She has also studied serial killers throughout history and shows how this is not a recent phenomenon with psychological autopsies of the fifteenth-century French war hero Gilles de Rais, the sixteenth-century Hungarian Countess Bathory, H. H. Holmes of the late ninteenth century, and Albert Fish of the Roaring Twenties.Through it all, Dr. Morrison has been on a mission to discover the reasons why serial killers are compelled to murder, how they choose their victims, and what we can do to prevent their crimes in the future. Her provocative conclusions will stun you.

    The book opens with his father's fond, vivid portrait of his son - a young man of extraordinary intellectual promise, who excelled at physics, math, and chess, but was also an active, good-hearted, and fun-loving kid. But the heart of the book is a description of the agonized months during which Gunther and his former wife Frances try everything in their power to halt the spread of Johnny's cancer and to make him as happy and comfortable as possible. In the last months of his life, Johnny strove hard to complete his high school studies. The scene of his graduation ceremony from Deerfield Academy is one of the most powerful - and heartbreaking - in the entire book. Johnny maintained his courage, wit and quiet friendliness up to the end of his life. He died on June 30, 1947, less than a month after graduating from Deerfield.

    This alarmed authorities, who feared certain "over-sexed" women could destroy civilization if allowed to reproduce and pass on their defects. Set against this backdrop, The Unfit Heiress chronicles the fight for inheritance, both genetic and monetary, between Ann Cooper Hewitt and her mother Maryon.In 1934, aided by a California eugenics law, the socialite Maryon Cooper Hewitt had her "promiscuous" daughter declared feebleminded and sterilized without her knowledge. She did this to deprive Ann of millions of dollars from her father's estate, which contained a child-bearing stipulation. When a sensational court case ensued, the American public was captivated. So were eugenicists, who saw an opportunity to restrict reproductive rights in America for decades to come.

    We were human toys. Just a piece of meat for someone to play with.'Barbara O'Hare was just 12 when she was admitted to the psychiatric hospital, Aston Hall, in 1971. From a troubled home, she'd hoped she would find sanctuary there. But within hours, Barbara was tied down, drugged with sodium amytal - a truth-telling drug - and then abused by its head physician, Dr Kenneth Milner.The terrifying drug experimentation and relentless abuse that lasted throughout her stay damaged her for life. But somehow, Barbara clung on to her inner strength and eventually found herself leading a campaign to demand answers for potentially hundreds of victims.A shocking account of how vulnerable children were preyed upon by the doctor entrusted with their care, and why it must never happen again.

    As he would later write in the first of a series of award-winning columns for "Vanity Fair," he suddenly found himself being deported "from the country of the well across the stark frontier that marks off the land of malady." Over the next eighteen months, until his death in Houston on December 15, 2011, he wrote constantly and brilliantly on politics and culture, astonishing readers with his capacity for superior work even in extremis.Throughout the course of his ordeal battling esophageal cancer, Hitchens adamantly and bravely refused the solace of religion, preferring to confront death with both eyes open. In this account of his affliction, he describes the torments of illness, discusses its taboos, and explores how disease transforms experience and changes our relationship to the world around us. By turns personal and philosophical, Hitchens embraces the full panoply of human emotions as cancer invades his body and compels him to grapple with the enigma of mortality.

    A classic story of survival and human endurance, told with humor, honesty, and heart, it became a worldwide best-seller and the Academy Award-winning blockbuster film of the same name. In 1970 Billy Hayes was an English major who left college in search of adventures to write about, like his hero Jack London. He had a rude awakening when he was arrested at the airport in Istanbul trying to board a plane while carrying four pounds of hashish, and given a life sentence. After five brutal years, relentless efforts by his family to gain his release, and endless escape plotting, Hayes finally took matters into his own hands. On a dark night, in a wailing storm he began a desperate and daring escape to freedom... This is the astounding journey, told in Billy Hayes's own words, of those five years of living hell and of the harrowing ordeal of his time on the run.

    The Psychopath Test is a fascinating journey through the minds of madness. Jon Ronson's exploration of a potential hoax being played on the world's top neurologists takes him, unexpectedly, into the heart of the madness industry. An influential psychologist who is convinced that many important CEOs and politicians are, in fact, psychopaths teaches Ronson how to spot these high-flying individuals by looking out for little telltale verbal and nonverbal clues. And so Ronson, armed with his new psychopath-spotting abilities, enters the corridors of power. He spends time with a death-squad leader institutionalized for mortgage fraud in Coxsackie, New York; a legendary CEO whose psychopathy has been speculated about in the press; and a patient in an asylum for the criminally insane who insists he's sane and certainly not a psychopath. Ronson not only solves the mystery of the hoax but also discovers, disturbingly, that sometimes the personalities at the helm of the madness industry are, with their drives and obsessions, as mad in their own way as those they study. And that relatively ordinary people are, more and more, defined by their maddest edges.