Complications lays bare a science not in its idealized form but as it actually is--uncertain, perplexing, and profoundly human.Complications is a 2002 National Book Award Finalist for Nonfiction.

    So we asked:What does yours mean to you? THE RESULT IS EXTRAORDINARY.Over 70 people have shared their stories. Powerful, funny, moving, this book is here to tell you:It's OK.With writing from: Adam Kay - Alastair Campbell - Alexis Caught - Ben Platt - Bryony Gordon - Candice Carty-Williams - Charlie Mackesy - Charly Cox - Chidera Eggerue - Claire Stancliffe - Davina McCall - Dawn O'Porter - Elizabeth Day - Elizabeth Uviebinené - Ella Purnell - Emilia Clarke - Emma Thompson - Eve Delaney - Fearne Cotton - Gabby Edlin - Gemma Styles - GIRLI (Milly Toomey) - Grace Beverley - Hannah Witton - Honey Ross - Hussain Manawer - Jack Rooke - James Blake - Jamie Flook - Jamie Windust - Jessie Cave - Jo Irwin - Jonah Freud - Jonny Benjamin - Jordan Stephens - Kai-Isaiah Jamal - Kate Weinberg - Kelechi Okafor - Khalil Aldabbas - KUCHENGA - Lauren Mahon - Lena Dunham - Maggie Matic - Martha Lane Fox - Mathew Kollamkulam - Matt Haig - Megan Crabbe - Michael Kitching - Michelle Elman - Miranda Hart - Mitch Price - Mona Chalabi - Montana Brown - Nadia Craddock - Naomi Campbell - Poorna Bell - Poppy Jamie - Reggie Yates - Ripley Parker - Robert Kazandjian - Rosa Mercuriadis - Saba Asif - Sam Smith - Scarlett Curtis - Scarlett Moffatt - Scottee - Sharon Chalkin Feldstein - Shonagh Marie - Simon Amstell - Steve Ali - Tanya Byron - Travon Free - Yomi Adegoke - Yusuf Al Majarhi

    Then, slowly, a mist settled deep inside the mind she once knew so well, blurring the world around her. She didn't know it then, but dementia was starting to take hold. In 2014, at age fifty-eight, she was diagnosed with young-onset Alzheimer's.Mitchell shares the heartrending story of her cognitive decline and how she has fought to stave it off. What lay ahead of her after the diagnosis was scary and unknowable, but Mitchell was determined and resourceful, and she vowed to outwit the disease for as long as she could.As Mitchell learned to embrace her new life, she began to see her condition as a gift, a chance to experience the world with fresh eyes and to find her own way to make a difference. Even now, her sunny outlook persists: She devotes her time to educating doctors, caregivers, and other people living with dementia, helping to reduce the stigma surrounding this insidious disease.Still living independently, Mitchell now uses Post-it notes and technology to remind her of her routines and has created a "memory room" where she displays photos--with labels--of her daughters, friends, and special places. It is a room where she feels calm and happy, especially on days when the mist descends.

    Born to survivalists in the mountains of Idaho, she prepared for the end of the world by stockpiling home-canned peaches and sleeping with her "head-for-the-hills bag". In the summer she stewed herbs for her mother, a midwife and healer, and in the winter she salvaged in her father's junkyard.Her father forbade hospitals, so Tara never saw a doctor or nurse. Gashes and concussions, even burns from explosions, were all treated at home with herbalism. The family was so isolated from mainstream society that there was no one to ensure the children received an education and no one to intervene when one of Tara's older brothers became violent.Then, lacking any formal education, Tara began to educate herself. She taught herself enough mathematics and grammar to be admitted to Brigham Young University, where she studied history, learning for the first time about important world events like the Holocaust and the civil rights movement. Her quest for knowledge transformed her, taking her over oceans and across continents, to Harvard and to Cambridge. Only then would she wonder if she'd traveled too far, if there was still a way home.Educated is an account of the struggle for self-invention. It is a tale of fierce family loyalty and of the grief that comes with severing the closest of ties. With the acute insight that distinguishes all great writers, Westover has crafted a universal coming-of-age story that gets to the heart of what an education is and what it offers: the perspective to see one's life through new eyes and the will to change it.

    She was a dedicated student with tons of extracurricular activities, friends, and loving parents at home.But after awakening from a vivid nightmare in which she was diagnosed with brain cancer, she was convinced the dream had been a warning. Allison believed that she must do something to stop the cancer in her dream from becoming a reality.It started with avoiding sidewalk cracks and quickly grew to counting steps as loudly as possible. Over the following weeks, her brain listed more dangers and fixes. She had to avoid hair dryers, calculators, cell phones, computers, anything green, bananas, oatmeal, and most of her own clothing.Unable to act “normal,” the once-popular Allison became an outcast. Her parents questioned her behavior, leading to explosive fights. When notebook paper, pencils, and most schoolbooks were declared dangerous to her health, her GPA imploded, along with her plans for the future.Finally, she allowed herself to ask for help and was diagnosed with obsessive-compulsive disorder. This brave memoir tracks Allison’s descent and ultimately hopeful climb out of the depths.

    Yalom uncovers the mysteries, frustrations, pathos, and humor at the heart of the therapeutic encounter. In recounting his patients' dilemmas, Yalom not only gives us a rare and enthralling glimpse into their personal desires and motivations but also tells us his own story as he struggles to reconcile his all-too human responses with his sensibility as a psychiatrist. Not since Freud has an author done so much to clarify what goes on between a psychotherapist and a patient.

    A slip of the hand and life ebbs away.The balance between life and death is so delicate, and the heart surgeon walks that rope between the two. In the operating room there is no time for doubt. It is flesh, blood, rib-retractors and pumping the vital organ with your bare hand to squeeze the life back into it. An off-day can have dire consequences – this job has a steep learning curve, and the cost is measured in human life. Cardiac surgery is not for the faint of heart.Professor Stephen Westaby took chances and pushed the boundaries of heart surgery. He saved hundreds of lives over the course of a thirty-five year career and now, in his astounding memoir, Westaby details some of his most remarkable and poignant cases – such as the baby who had suffered multiple heart attacks by six months old, a woman who lived the nightmare of locked-in syndrome, and a man whose life was powered by a battery for eight years.A powerful, important and incredibly moving book, Fragile Lives offers an exceptional insight into the exhilarating and sometimes tragic world of heart surgery, and how it feels to hold someone’s life in your hands.

    When a small vial arrives in her mailbox from "Lewis Carroll," Ayelet Waldman is at a low point. Her mood storms have become intolerably severe; she has tried nearly every medication possible; her husband and children are suffering with her. So she opens the vial, places two drops on her tongue, and joins the ranks of an underground but increasingly vocal group of scientists and civilians successfully using therapeutic microdoses of LSD. As Waldman charts her experience over the course of a month--bursts of productivity, sleepless nights, a newfound sense of equanimity--she also explores the history and mythology of LSD, the cutting-edge research into the drug, and the byzantine policies that control it. Drawing on her experience as a federal public defender, and as the mother of teenagers, and her research into the therapeutic value of psychedelics, Waldman has produced a book that is eye-opening, often hilarious, and utterly enthralling.

    It is 4 a.m. I have run arrest calls, treated life-threatening bleeding, held the hand of a young woman dying of cancer, scuttled down miles of dim corridors wanting to sob with sheer exhaustion, forgotten to eat, forgotten to drink, drawn on every fibre of strength that I possess to keep my patients safe from harm.'How does it feel to be spat out of medical school into a world of pain, loss and trauma that you feel wholly ill-equipped to handle? To be a medical novice who makes decisions which - if you get them wrong - might forever alter, or end, a person's life?In 'Your Life in My Hands', television journalist turned junior doctor Rachel Clarke captures the extraordinary realities of life on the NHS frontline. During last year's historic junior doctor strikes, Rachel was at the forefront of the campaign against the government's imposed contract upon young doctors. Her heartfelt, deeply personal account of life as a junior doctor in today's NHS is both a powerful polemic on the degradation of Britain's most vital public institution and a love letter of optimism and hope to that same health service.

    PublicationA major literary event--the complete, uncensored journals of Sylvia Plath, published in their entirety for the first time.Sylvia Plath's journals were originally published in 1982 in a heavily abridged version authorized by Plath's husband, Ted Hughes. This new edition is an exact and complete transcription of the diaries Plath kept during the last twelve years of her life. Sixty percent of the book is material that has never before been made public, more fully revealing the intensity of the poet's personal and literary struggles, and providing fresh insight into both her frequent desperation and the bravery with which she faced down her demons. The complete Journals of Sylvia Plath is essential reading for all who have been moved and fascinated by Plath's life and work.

    Until one day, aged 18, she went on a diet. That didn’t stop. Then couldn’t stop. That trapped her in ‘a secret world of eating-related happiness and unhappiness’. And saw her weight swiftly drop to below six stone. A grippingly honest account of life with anorexia nervosa, Thin is Grace’s heartbreaking, shocking and, finally, inspirational story. A memoir that is in part insider’s exposé and in part survivor’s testimony, it explains the struggle for self-discovery, and chronicles the devastating battles waged for control over mind and body. Breaking secrets, Grace shatters the myths surrounding this widely misunderstood illness, helping those bound within the rules of anorexia to find a way out, and those on the outside to understand more.Thin also has resonance beyond the world of eating disorders. For in daring to tell the truth, Grace reveals her extraordinary story to be a common one, reflected in the shape of many of our lives. She draws on the universal themes of female self-image and self-determination, which have inspired such classics as The Bell Jar and A Room of One’s Own, to shatter the myths surrounding anorexia. And the powerful insights she brings to overcoming addiction make this an invaluable narrative for all those looking to find hope and renewal in the acceptance of change and growth.Thin is the most eloquent account of anorexia yet.

    Imprisoned in the Buchenwald concentration camp, they miraculously survive the Nazis’ murderous brutality.Then Gustav learns he is being sent to Auschwitz—and certain death.For Fritz, letting his father go is unthinkable. Desperate to remain together, Fritz makes an incredible choice: he insists he must go too. To the Nazis, one death camp is the same as another, and so the boy is allowed to follow. Throughout the six years of horror they witness and immeasurable suffering they endure as victims of the camps, one constant keeps them alive: their love and hope for the future. Based on the secret diary that Gustav kept as well as meticulous archival research and interviews with members of the Kleinmann family, including Fritz’s younger brother Kurt, sent to the United States at age eleven to escape the war, The Boy Who Followed His Father into Auschwitz is Gustav and Fritz’s story—an extraordinary account of courage, loyalty, survival, and love that is unforgettable.

    It contains 100,000 books, spread over a mile of shelving, with twisting corridors and roaring fires, and all set in a beautiful, rural town by the edge of the sea. A book-lover's paradise? Well, almost ... In these wry and hilarious diaries, Shaun provides an inside look at the trials and tribulations of life in the book trade, from struggles with eccentric customers to wrangles with his own staff, who include the ski-suit-wearing, bin-foraging Nicky. He takes us with him on buying trips to old estates and auction houses, recommends books (both lost classics and new discoveries), introduces us to the thrill of the unexpected find, and evokes the rhythms and charms of small-town life, always with a sharp and sympathetic eye.

    Thinking this is his rock bottom, little does James know that by the end of the year he will have befouled himself in a Los Angeles steakhouse and disrespected a pensioner on television. Luckily, there is one thing he can rely on for comfort – music. In true Acaster fashion, this ends up with a completely unnecessary mission: to buy as much music as he can released in 2016, the year before everything went wrong (for James, at least). Some albums are life-changing masterpieces, others are ‘Howdilly Doodilly’ by Okilly Dokilly, a metalcore album devoted to The Simpsons character Ned Flanders. But all of them play a part in the year that James gets his life back on track.In PERFECT SOUND WHATEVER, James takes us through the music of 2016, the bullshit of 2017, and how the beauty of one defeated the ugliness of the other. He will also reveal how he stole a cookie from Clint Eastwood and attempted to complete his musical odyssey by reforming one of Kettering’s most overlooked bands.

    But as the twins approached adolescence, Pamela began to succumb to schizophrenia, hearing disembodied voices and eventually suffering many breakdowns and hospitalizations.Divided Minds is a dual memoir of identical twins, one of whom faces a life sentence of schizophrenia, and the other who becomes a psychiatrist, after entering the spotlight that had for so long been focused on her sister. Told in the alternating voices of the sisters, Divided Minds is a heartbreaking account of the far reaches of madness, as well as the depths of ambivalence and love between twins. It is a true and unusually frank story of identical twins with very different identities and wildly different experiences of the world around them.