Next, he examines the three critiques that currently challenge this classic Darwinian edifice: that selection operates on multiple levels, from the gene to the group; that evolution proceeds by a variety of mechanisms, not just natural selection; and that causes operating at broader scales, including catastrophes, have figured prominently in the course of evolution.Then, in a stunning tour de force that will likely stimulate discussion and debate for decades, Gould proposes his own system for integrating these classical commitments and contemporary critiques into a new structure of evolutionary thought.In 2001 the Library of Congress named Stephen Jay Gould one of America's eighty-three Living Legends--people who embody the quintessentially American ideal of individual creativity, conviction, dedication, and exuberance. Each of these qualities finds full expression in this peerless work, the likes of which the scientific world has not seen--and may not see again--for well over a century.

    It covers everything from its recreational use in the dance community, its use as an adjunct to psychotherapy as an aid in overcoming chemical dependency and alcoholism, to the types of mystical experiences induced by ketamine. This book includes information on the possible benfits and dangers of ketamine use along with an authoratative treatment plan for individuals who become addicted to the drug. It is wealth of information for both laypersons and medical professionals alike.

    The sixteenth and seventeenth centuries witnessed the Copernican Revolution, which bodychecked the Earth as the pivot point of creation and joined us with the rest of the cosmos as one planet among many orbiting the Sun. Three centuries later came the second great scientific revolution: the Darwinian Revolution. It removed us from a distinct, divine biological status to place us wholly in the ebb and flow of all terrestrial life. This book describes how we’re in the midst of a third great scientific revolution, five centuries in the making: the Stardust Revolution. It is the merging of the once-disparate realms of astronomy and evolutionary biology, and of the Copernican and Darwinian Revolutions, placing life in a cosmic context. This book takes readers on a grand journey that begins on the summit of California’s Mount Wilson, where astronomers first realized that the universe is both expanding and evolving, to a radio telescope used to identify how organic molecules—the building blocks of life—are made by stars. It’s an epic story told through a scientific cast that includes some of the twentieth century’s greatest minds—including Nobel laureate Charles Townes, who discovered cosmic water—as well as the most ambitious scientific explorers of the twenty-first century, those racing to find another living planet. Today, an entirely new breed of scientists—astrobiologists and astrochemists—are taking the study of life into the space age. Astrobiologists study the origins, evolution, and distribution of life, not just on Earth, but in the universe. Stardust science is filling in the missing links in our evolutionary story, ones that extend our family tree back to the stars.

    While some books explore our genetic inheritance and popular television shows celebrate ancestry, this is the first book to explore how everything from DNA to emotions to names and the stories that form our lives are all part of our human legacy. This book shows how trust is inherited in Africa, silence is passed down in Tasmania, and how the history of nations is written in our DNA. From fateful, ancient encounters to modern mass migrations and medical diagnoses, Kenneally explains how the forces that shaped the history of the world ultimately shape each human who inhabits it. The Invisible History of the Human Race is a deeply researched, carefully crafted, and provocative perspective on how our stories, psychology, and genetics affect our past and our future.

    It draws on all the latest knowledge from anthropology and archaeology, via genetics and evolution, to psychology and medicine. It tackles issues such as hereditary genes in criminal behaviour and homosexuality.

    People in this middle place have sustained traumatic brain injuries or are the victims of stroke or degenerative diseases, such as Alzheimer’s and Parkinson’s. Many are oblivious to the outside world, and their doctors believe they are incapable of thought. But a sizeable number are experiencing something different: intact minds adrift deep within damaged brains and bodies. Following Owen’s journey of exciting medical discovery, Into the Gray Zone asks some tough and terrifying questions, such as: What is life like for these patients? What can their families and friends do to help them? What are the ethical implications for religious organizations, politicians, the Right to Die movement, and even insurers? And perhaps most intriguing of all: in defining what a life worth living is, are we too concerned with the physical and not giving enough emphasis to the power of thought? What, truly, defines a satisfying life?

    By extracting the fundamental concepts from this enormous and ever-growing field, the authors tell the story of cell biology, and create a coherent framework through which non-expert readers may approach the subject. Written in clear and concise language, and beautifully illustrated, the book is enjoyable to read, and it provides a clear sense of the excitement of modern biology. Molecular Biology of the Cell sets forth the current understanding of cell biology (completely updated as of Autumn 2001), and it explores the intriguing implications and possibilities of the great deal that remains unknown. The hallmark features of previous editions continue in the Fourth Edition. The book is designed with a clean and open, single-column layout. The art program maintains a completely consistent format and style, and includes over 1,600 photographs, electron micrographs, and original drawings by the authors. Clear and concise concept headings introduce each section. Every chapter contains extensive references. Most important, every chapter has been subjected to a rigorous, collaborative revision process where, in addition to incorporating comments from expert reviewers, each co-author reads and reviews the other authors' prose. The result is a truly integrated work with a single authorial voice. Features : - Places the latest hot topics sensibly in context - including genomics, protein structure, array technology, stem cells and genetics diseases. - Incorporates and emphasises new genomic data. - All of molecular biology is brought together into one section (chapters 4-7) covering classically defined molecular biology and molecular genetics. - Two chapters deal exclusively with methods and contain information on the latest tools and techniques. - New chapters on "Pathogens, Infection, and Innate Immunity". - Cell Biology Interactive CD-ROM is packaged with every copy of the book. - Contains over 1,600 illustrations, electron micrographs and photographs, of which over 1,000 are originally conceived by the authors.

    The Human Genome Project finished sequencing human DNA. It seemed it was only a matter of time until we had all the answers to the secrets of life on this planet. The cutting-edge of biology, however, is telling us that we still don't even know all of the questions. How is it that, despite each cell in your body carrying exactly the same DNA, you don't have teeth growing out of your eyeballs or toenails on your liver? How is it that identical twins share exactly the same DNA and yet can exhibit dramatic differences in the way that they live and grow? It turns out that cells read the genetic code in DNA more like a script to be interpreted than a mould that replicates the same result each time. This is epigenetics and it's the fastest-moving field in biology today. The Epigenetics Revolution traces the thrilling path this discipline has taken over the last twenty years. Biologist Nessa Carey deftly explains such diverse phenomena as how queen bees and ants control their colonies, why tortoiseshell cats are always female, why some plants need a period of cold before they can flower, why we age, develop disease and become addicted to drugs, and much more. Most excitingly, Carey reveals the amazing possibilities for humankind that epigenetics offers for us all - and in the surprisingly near future.

    A lyrical journey from hope to despair and back again, The First Cell explores cancer from every angle: medical, scientific, cultural, and personal. Indeed, Raza describes how she bore the terrible burden of being her own husband's oncologist as he succumbed to leukemia. Like When Breath Becomes Air, The First Cell is no ordinary book of medicine, but a book of wisdom and grace by an author who has devoted her life to making the unbearable easier to bear.

    Readers will continue to enjoy the current, concise, and straightforward approach to the field that made previous editions so popular. They'll understand the experimental observations that underlie the science of immunology at the molecular, cellular, and whole organism level-and explore the conclusions that can be drawn from those observations.The smart way to study!Elsevier titles with STUDENT CONSULT will help you master difficult concepts and study more efficiently in print and online! Perform rapid searches. Integrate bonus content from other disciplines. Download text to your handheld device. And a lot more. Each STUDENT CONSULT title comes with full text online, a unique image library, case studies, USMLE style questions, and online note-taking to enhance your learning experience.Highlights the implications of immunologic science for the management of human disease.Features over 365 full-color illustrations that highlight important processes and concepts, and bring the three-dimensional structures of molecules to life. Offers a wealth of reader-friendly features including major concepts highlighted in bold italics - at-a-glance boxes that present specialized information and explanations of current technological approaches - a wealth of tables that summarize key information - a glossary of terms - a CD Molecule Appendix that reflects the latest properties of known CD Molecules - an appendix on immunologic laboratory techniques - and more.Includes free access to a full-text online version, a downloadable collection of full-color images, sophisticated immunologic animations, integration links to bonus content in other STUDENT CONSULT titles, content clipping for handhelds, and more - all through the STUDENT CONSULT website at www.studentconsult.com.Incorporates the newest understandings of basic science as well as the newest research findings.Includes new information on the organization of lymphoid organs and mechanisms of innate immunity.Presents enhanced, more straightforward explanations of subjects such as of antigen-presenting cells and the biology of T cell activation.

    It recounts the life histories of those who had been victims of the 1920s encephalitis lethargica epidemic. Sacks chronicles his efforts in the late 1960s to help these patients at the Beth Abraham Hospital in the Bronx, New York.

    And as outbreaks of COVID-19, Ebola, MERS, and Zika have demonstrated, we are woefully underprepared to deal with the fallout. So what can -- and must -- we do in order to protect ourselves from mankind's deadliest enemy?Drawing on the latest medical science, case studies, policy research, and hard-earned epidemiological lessons, Deadliest Enemy explores the resources and programs we need to develop if we are to keep ourselves safe from infectious disease. The authors show how we could wake up to a reality in which many antibiotics no longer cure, bioterror is a certainty, and the threat of a disastrous influenza or coronavirus pandemic looms ever larger. Only by understanding the challenges we face can we prevent the unthinkable from becoming the inevitable.Deadliest Enemy is high scientific drama, a chronicle of medical mystery and discovery, a reality check, and a practical plan of action.

    This updated edition includes a new Introduction and a new final chapter exposing frightening developments in recent years, including the black market that emerged in chemical and biological weapons following the breakup of the Soviet Union, the acquisition of these weapons by various Third World states, the attempts of countries such as Iraq to build up arsenals, and--particularly and most recently--the use of these weapons in terrorist attacks.

    Based on selective breeding of human beings, eugenics began in laboratories on Long Island but ended in the concentration camps of Nazi Germany. Cruel and racist laws were enacted in 27 U.S. states, while the supporters of eugenics included progressive thinkers like Woodrow Wilson, Margaret Sanger and Oliver Wendell Holmes. Ultimately, over 60,000 "unfit" Americans were coercively sterilized, a third of them after Nuremberg had declared such practices crimes against humanity. This is a timely and shocking chronicle of bad science at its worst—with many important lessons for the genetic age in which an interest in eugenics has been dangerously revived.

    A caring and thoughtful doctor, he also writes beautifully.” —Siddhartha Mukherjee, New York Times bestselling author on Modern Death In Heart of the Matter, Dr. Haider Warraich takes readers inside the ER, inside patients' rooms, and inside the history and technology of heart disease.More people die of heart disease than any other disease in the world, including even cancer. In fact, deaths from heart disease are on the rise around the world and in the United States. When any heart disease becomes advanced enough, it results in the development of heart failure. In the United States, heart failure is the most common reason for admission to the hospital. Heart failure strikes both the abject and the affluent. And yet, even the most basic facts about heart failure remain known by few who don’t work in medicine for a living. Many patients develop heart failure without having any problems with their coronary arteries. Heart failure can affect anyone at any time: a child recovering from a viral infection, a woman who has just given birth, a cancer patient who received chemotherapy or anyone with any number of common conditions such as high blood pressure, diabetes, or sleep apnea.Warraich's signature blend of lucid writing and compelling narrative explores the complex discussion about heart failure with accessibility and compassion.