Costa takes readers on a journey from Darwin’s childhood through his voyage on the HMS Beagle, where his ideas on evolution began, and on to Down House, his bustling home of forty years. Using his garden and greenhouse, the surrounding meadows and woodlands, and even the cellar and hallways of his home-turned-field-station, Darwin tested ideas of his landmark theory of evolution through an astonishing array of experiments without using specialized equipment. From those results, he plumbed the laws of nature and drew evidence for the revolutionary arguments of On the Origin of Species and other watershed works.This unique perspective introduces us to an enthusiastic correspondent, collaborator, and, especially, an incorrigible observer and experimenter. And it includes eighteen experiments for home, school, or garden.

    An illustrated history of opium culture follows the path of the drug's creation and consumption and discusses how it fueled the vision of artists, writers, and poets.

    Days later, the madman was dead and Denis was framed for murder. A riveting exposé of the fierce debates, deadly politics, and cutthroat rivalries behind the first transfusion experiments, Blood Work takes us from dissection rooms in palaces to the streets of Paris, providing an unforgettable portrait of an era that wrestled with the same questions about morality and experimentation that haunt medical science today.

    Ratey provides insight into the basic structure and chemistry of the brain, and demonstrates how its systems shape our perceptions, emotions, and behavior. By giving us a greater understanding of how the brain responds to the guidance of its user, he provides us with knowledge that can enable us to improve our lives.In A User’s Guide to the Brain, Ratey clearly and succinctly surveys what scientists now know about the brain and how we use it. He looks at the brain as a malleable organ capable of improvement and change, like any muscle, and examines the way specific motor functions might be applied to overcome neural disorders ranging from everyday shyness to autism. Drawing on examples from his practice and from everyday life, Ratey illustrates that the most important lesson we can learn about our brains is how to use them to their maximum potential.

    David A. Kessler explains why Americans suffer in unprecedented numbers from obesity, heart disease, diabetes, and other debilitating illnesses, and offers concrete solutions for reducing cardiovascular problems, keeping weight off, and curtailing chronic disease.The American body is in trouble. Heart disease is the number one cause of death in the United States today, and millions are plagued by conditions like obesity and diabetes. But we have the answer to improving health and longevity: 1) cut out fast carbs (processed foods); 2) reduce saturated fats; 3) exercise regularly.Though the solution is simple, the difficulty lies in the food we eat. Multi-billion-dollar processing plants and food manufacturers dot the heartland and work to increase the profits of the industrialized farming business—Big Agriculture—that produces excess corn and wheat. Today, we are being fed highly palatable, ultra-processed carbohydrates as food products—fast carbs—that are often marketed as “healthy.” Fast carbs are primarily starches and sugars produced during food processing and are present in much of what we eat. By destroying the healthy structure of whole food and increasing the amount of rapidly digestible starch it contains, these products bypass our body’s metabolic pathways. When combined with the ill-effects of saturated fats, we are putting ourselves on a collision course with weight gain, insulin resistance, digestive issues, heart disease, and more.The problem is, most of us don’t know where these fast carbs and saturated fats lurk in our daily diets. Accessible and eye-opening, Fast Carbs, Slow Carbs provides the information we need to understand exactly what we are eating—and to learn the truth about what it being sold to us as “healthy” food. Rising above the confusing range of specific popular diets—Keto, Paleo, Mediterranean, Vegan, Vegetarian—Dr. Kessler gives us an achievable baseline that can set us on the path to better health.

     Early studies of the functions of the human brain used a simple method: wait for misfortune to strike-strokes, seizures, infectious diseases, lobotomies, horrendous accidents-and see how the victim coped. In many cases survival was miraculous, and observers could only marvel at the transformations that took place afterward, altering victims' personalities. An injury to one section can leave a person unable to recognize loved ones; some brain trauma can even make you a pathological gambler, pedophile, or liar. But a few scientists realized that these injuries were an opportunity for studying brain function at its extremes. With lucid explanations and incisive wit, Sam Kean explains the brain's secret passageways while recounting forgotten stories of common people whose struggles, resiliency, and deep humanity made modern neuroscience possible.

    Known as Monsanto’s Roundup by consumers, and as glyphosate by scientists, the world’s most popular weed killer is used everywhere from backyard gardens to golf courses to millions of acres of farmland. For decades it’s been touted as safe enough to drink, but a growing body of evidence indicates just the opposite, with research tying the chemical to cancers and a host of other health threats. In Whitewash, veteran journalist Carey Gillam uncovers one of the most controversial stories in the history of food and agriculture, exposing new evidence of corporate influence. Gillam introduces readers to farm families devastated by cancers which they believe are caused by the chemical, and to scientists whose reputations have been smeared for publishing research that contradicted business interests. Readers learn about the arm-twisting of regulators who signed off on the chemical, echoing company assurances of safety even as they permitted higher residues of the herbicide in food and skipped compliance tests. And, in startling detail, Gillam reveals secret industry communications that pull back the curtain on corporate efforts to manipulate public perception. Whitewash is more than an exposé about the hazards of one chemical or even the influence of one company. It’s a story of power, politics, and the deadly consequences of putting corporate interests ahead of public safety.

    Its organization and thoroughness are unsurpassed, putting it above similar review books. Students who thoroughly read this book should have no trouble successfully completing their psychiatry clerkship and passing the shelf exam. As course director for the core psychiatry clerkship at my institution, I will recommend this book to students."--Doody's Review Service"First Aid for the Psychiatry Clerkship" gives you the core information needed to impress on the wards and pass the psychiatry clerkship exam. Written by students who know what it takes to succeed, and based on the national guidelines for the psychiatry clerkship, the book is filled with mnemonics, ward and exam tips, tables, clinical images, algorithms, and newly added mini-cases.Features Completely revised based on the psychiatry clerkship's core competencies Written by medical students who passed and reviewed by faculty for accuracy NEW integrated mini-cases illustrate classic patient presentations and/or commonly tested scenarios NEW illustrations and management algorithms Updated throughout with enhanced sections on medications, depression/anxiety, and child psychiatry Helps students hone in on the most important concepts for the clerkship and the examThe content you need to ace the clerkship: Section I: How to Succeed in the Psychiatry Clerkship Section II: High-Yield Facts; Examination and Diagnosis; Psychotic Disorders; Mood Disorders; Anxiety and Adjustment Disorders; Personality Disorders; Substance-Related Disorders; Cognitive Disorders; Geriatric Disorders; Psychiatric Disorders in Children; Dissociative Disorders; Somataform and Factitious Disorders; Impulse Control Disorders; Eating Disordes; Disorders; Sleep Disorders; Sexual Disorders; Psychtherapies; Psychopharmacology; Legal Issues; Section III: Awards and Opportunities.

    government’s Human Genome Project. Venter hoped that by decoding the genome ahead of schedule, he would speed up the pace of biomedical research and save the lives of thousands of people. He also hoped to become very famous and very rich. Calling his company Celera (from the Latin for “speed”), he assembled a small group of scientists in an empty building in Rockville, Maryland, and set to work.At the same time, the leaders of the government program, under the direction of Francis Collins, head of the National Human Genome Research Institute at the National Institutes of Health, began to mobilize an unexpectedly unified effort to beat Venter to the prize—knowledge that had the potential to revolutionize medicine and society. The stage was set for one of the most thrilling—and important—dramas in the history of science. The Genome War is the definitive account of that drama—the race for the greatest prize biology has had to offer, told by a writer with exclusive access to Venter’s operation from start to finish. It is also the story of how one man’s ambition created a scientific Camelot where, for a moment, it seemed that the competing interests of pure science and commercial profit might be gloriously reconciled—and the national repercussions that resulted when that dream went awry.From the Hardcover edition.

    Ramachandran, now shares his unique insight into human consciousness in an entertaining, inspiring, and intellectually dazzling brief tour of the ultimate frontier—the thoughts in our heads.A Brief Tour of Human Consciousness is made up of five investigations of the greatest mysteries of the brain. The first chapter shows how amputees feel pain in limbs they no longer have as it introduces the great revolution of our age: neuroscience. The second chapter walks through the way what we see determines our thoughts, and demonstrates the counterintuitive point that believing is in fact seeing. The third chapter takes a leap beyond cutting edge science to audaciously set out a general theory of beauty, explaining why, the world over, cultures have fundamentally similar notions of what is attractive. The fourth chapter explores the bizarre world of synesthetes, people who see colors in numbers, textures in smells, sounds in sights, and flavors in sounds. Finally, V. S. Ramachandran one of the foremost brain researchers in the world today, sums up the implications of the revolution in our understanding of consciousness, to make a fascinating argument about our essential sense of self and its distributed nature.

    To understand this remarkable trend, Charles R. Morris "embedded" himself with a surgical team at New York-Presbyterian Hospital in New York City, one of the world's premier cardiac surgery and transplant centers. Given unprecedented access, Morris witnessed sophisticated operations and observed the tense meetings where surgeons relentlessly criticize their own performance. In thrilling detail, Morris recounts a late-night against-the-clock "harvest run" to secure a precious transplantable organ; the heart-breaking story of a child's failed transplant; a trainee surgeon's brutal daily regimen; and much more. Along the way, Morris documents the fifty years of research and hundreds of millions of dollars that have been expended on creating a reliable mechanical heart, and he steps back to reflect on how doctors think and how they judge each other, what is really driving health care costs, and the future of health care policy in America.

    

    It is the history of who you are and how you came to be. It is unique to you, as it is to each of the 100 billion modern humans who have ever drawn breath. But it is also our collective story, because in every one of our genomes we each carry the history of our species births, deaths, disease, war, famine, migration, and a lot of sex. Since scientists first read the human genome in 2001, it has been subject to all sorts of claims, counterclaims, and myths. In fact, as Adam Rutherford explains, our genomes should be read not as instruction manuals, but as epic poems. DNA determines far less than we have been led to believe about us as individuals, but vastly more about us as a species. In this captivating journey through the expanding landscape of genetics, Adam Rutherford reveals what our genes now tell us about history, and what history tells us about our genes. From Neanderthals to murder, from redheads to race, dead kings to plague, evolution to epigenetics, this is a demystifying and illuminating new portrait of who we are and how we came to be."

    What at first seemed like a case of food poisoning quickly turned critical, and by the time Tom had been transferred via emergency medevac to the world-class medical center at UC San Diego, where both he and Steffanie worked, blood work revealed why modern medicine was failing: Tom was fighting one of the most dangerous, antibiotic-resistant bacteria in the world.Frantic, Steffanie combed through research old and new and came across phage therapy: the idea that the right virus, aka "the perfect predator," can kill even the most lethal bacteria. Phage treatment had fallen out of favor almost 100 years ago, after antibiotic use went mainstream. Now, with time running out, Steffanie appealed to phage researchers all over the world for help. She found allies at the FDA, researchers from Texas A&M, and a clandestine Navy biomedical center -- and together they resurrected a forgotten cure.

    Sybil became both a pop phenomenon and a revolutionary force in the psychotherapy industry. The book rocketed multiple personality disorder (MPD) into public consciousness and played a major role in having the diagnosis added to the psychiatric bible, Diagnostic and Statistical Manual of Mental Disorders. But what do we really know about how Sybil came to be? In her news-breaking book Sybil Exposed, journalist Debbie Nathan gives proof that the allegedly true story was largely fabricated. The actual identity of Sybil (Shirley Mason) has been available for some years, as has the idea that the book might have been exaggerated. But in Sybil Exposed, Nathan reveals what really powered the legend: a trio of women—the willing patient, her ambitious shrink, and the imaginative journalist who spun their story into bestseller gold. From horrendously irresponsible therapeutic practices—Sybil’s psychiatrist often brought an electroshock machine to Sybil’s apartment and climbed into bed with her while administering the treatment— to calculated business decisions (under an entity they named Sybil, Inc., the women signed a contract designating a three-way split of profits from the book and its spin-offs, including board games, tee shirts, and dolls), the story Nathan unfurls is full of over-the-top behavior. Sybil’s psychiatrist, driven by undisciplined idealism and galloping professional ambition, subjected the young woman to years of antipsychotics, psychedelics, uppers, and downers, including an untold number of injections with Pentothal, once known as “truth serum” but now widely recognized to provoke fantasies. It was during these “treatments” that Sybil produced rambling, garbled, and probably “false-memory”–based narratives of the hideous child abuse that her psychiatrist said caused her MPD. Sybil Exposed uses investigative journalism to tell a fascinating tale that reads like fiction but is fact. Nathan has followed an enormous trail of papers, records, photos, and tapes to unearth the lives and passions of these three women. The Sybil archive became available to the public only recently, and Nathan examined all of it and provides proof that the story was an elaborate fraud—albeit one that the perpetrators may have half-believed. Before Sybil was published, there had been fewer than 200 known cases of MPD; within just a few years after, more than 40,000 people would be diagnosed with it. Set across the twentieth century and rooted in a time when few professional roles were available to women, this is a story of corrosive sexism, unchecked ambition, and shaky theories of psychoanalysis exuberantly and drastically practiced. It is the story of how one modest young woman’s life turned psychiatry on its head and radically changed the course of therapy, and our culture, as well.