In 1996 Joseph LeDoux's "The Emotional Brain" presented a revelatory examination of the biological bases of our emotions and memories. Now, the world-renowned expert on the brain has produced with a groundbreaking work that tells a more profound story: how the little spaces between the neurons-the brain's synapses--are the channels through which we think, act, imagine, feel, and remember. Synapses encode the essence of personality, enabling each of us to function as a distinctive, integrated individual from moment to moment. Exploring the functioning of memory, the synaptic basis of mental illness and drug addiction, and the mechanism of self-awareness, "Synaptic Self" is a provocative and mind-expanding work that is destined to become a classic.

    He takes us on a journey through the laboratories where scientists are studying every aspect of the cell--DNA, mitochondria, stem cells, our immune systems, even age genes that can lead to a tenfold increase in life span (in worms, anyway)--all in an effort to forestall or reverse the body's (currently!) inevitable decline. With clear writing and intellectual passion, Steele shines a spotlight on a revolution already under way and offers reality-based hope.

    Literate and authoritative--.Marvelously exciting." --The New York Times Book ReviewJonathan Weiner, winner of the Pulitzer Prize for The Beak of the Finch, brings his brilliant reporting skills to the story of Seymour Benzer, the Brooklyn-born maverick scientist whose study of genetics and experiments with fruit fly genes has helped revolutionize or knowledge of the connections between DNA and behavior both animal and human.How much of our fate is decided before we are born?  Which of our characteristics is inscribed in our DNA? Weiner brings us into Benzer's Fly Rooms at the California Institute of Technology, where Benzer, and his asssociates are in the process of finding answers, often astonishing ones, to these questions. Part biography, part thrilling scientific detective story, Time, Love, Memory forcefully demonstrates how Benzer's studies are changing our world view--and even our lives.

    Authors Peter Tompkins and Christopher Bird suggest that the most far-reaching revolution of the 20th century — one that could save or destroy the planet — may come from the bottom of your garden."Almost incredible ... bristles with plenty of hard facts and astounding scientific and practical lore." —S. K. Oberbeck, Newsweek“This fascinating book roams ... over that marvelous no man's land of mystical glimmerings into the nature of science and life itself." —Henry Mitchell, Washington Post Book World“If I can't ‘get inside a plant’ or ‘feel emanations’ from a plant and don't know anyone else who can. that doesn't detract one whit from the possibility that some people can and do. . . .According to The Secret Life of Plants, plants and men do inter-relate, with plants exhibiting empathetic and spiritual relationships and showing reactions interpreted as demonstrating physical-force connections with men. As my students say, ‘hey, wow!’"—Richard M. Klein, Professor of Botany, University of Vermont (in Smithsonian)

    But by itself, DNA is just an inert blueprint for life. It is the ribosome--an enormous molecular machine made up of a million atoms--that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases. But this is also a human story of Ramakrishnan's unlikely journey, from his first fumbling experiments in a biology lab to being the dark horse in a fierce competition with some of the world's best scientists. In the end, Gene Machine is a frank insider's account of the pursuit of high-stakes science.

    Nancy Butcher has gathered together some of the most unusual natural cures that have been proven effective today, and even throws in some unbelievable and-thankfully-abandoned therapies from times past.Filled with case histories of unique illnesses, historic documentation of strange medical practices, and the author's own insightful commentary, this book explains not only how to cure headaches, sleep better, and improve your sex life, but also that people with Cotard's syndrome actually believe they are dead.

    

    The human system for processing sound is a biological marvel, an intricate assembly of delicate membranes, bones, receptor cells, and neurons. Yet many people take their ears for granted, abusing them with loud restaurants, rock concerts, and Q-tips. And then, eventually, most of us start to go deaf.Millions of Americans suffer from hearing loss. Faced with the cost and stigma of hearing aids, the natural human tendency is to do nothing and hope for the best, usually while pretending that nothing is wrong. In Volume Control, David Owen argues this inaction comes with a huge social cost. He demystifies the science of hearing while encouraging readers to get the treatment they need for hearing loss and protect the hearing they still have.Hearing aids are rapidly improving and becoming more versatile. Inexpensive high-tech substitutes are increasingly available, making it possible for more of us to boost our weakening ears without bankrupting ourselves. Relatively soon, physicians may be able to reverse losses that have always been considered irreversible. Even the insistent buzz of tinnitus may soon yield to relatively simple treatments and techniques. With wit and clarity, Owen explores the incredible possibilities of technologically assisted hearing. And he proves that ears, whether they're working or not, are endlessly interesting.

    Beginning in the 1950s when doctors still paid house calls but regularly withheld the truth from their patients, Amy Gutmann and Jonathan D. Moreno explore an unprecedented revolution in health care and explain the problem with America’s wanting everything that medical science has to offer without debating its merits and its limits. The result: Americans today pay far more for health care while having among the lowest life expectancies and highest infant mortality of any affluent nation.Gutmann and Moreno—“incisive, influential, and pragmatic thinkers” (Arthur Caplan)—demonstrate that the stakes have never been higher for prolonging and improving life. From health care reform and death-with-dignity to child vaccinations and gene editing, they explain how bioethics came to dominate the national spotlight, leading and responding to a revolution in doctor-patient relations, a burgeoning world of organ transplants, and new reproductive technologies that benefit millions but create a host of legal and ethical challenges.With striking examples, the authors show how breakthroughs in cancer research, infectious disease, and drug development provide Americans with exciting new alternatives, yet often painful choices. They address head-on the most fundamental challenges in American health care: Why do we pay so much for health care while still lacking universal coverage? How can medical studies adequately protect individuals who volunteer for them? What’s fair when it comes to allocating organs for transplants in truly life-and-death situations?A lucid and provocative blend of history and public policy, this urgent work exposes the American paradox of wanting to have it all without paying the price.

    Mysteries don't lose their poetry because they are solved: the solution often is more beautiful than the puzzle, uncovering deeper mysteries. With the wit, insight, and spellbinding prose that have made him a best-selling author, Dawkins takes up the most important and compelling topics in modern science, from astronomy and genetics to language and virtual reality, combining them in a landmark statement of the human appetite for wonder. This is the book Richard Dawkins was meant to write: a brilliant assessment of what science is (and isn't), a tribute to science not because it is useful but because it is uplifting.

    From biblical plagues, to the AIDS crisis, to supergerms of the future, this updated and revised edition of the original covers the whole gamut of diseases that have threatened humanity since its origins.It also includes a new chapter on the history of bioterrorism and the deplorable role it has played and is likely to play in the phenomenal diversity of diseases.

    He is one of the foremost figures of contemporary neuroscience, and his decades-long quest to understand the inner workings of the brain’s memory machine has begun to pay off. Award-winning journalist Terry McDermott spent nearly two years observing Lynch at work and now gives us a fascinating and dramatic account of daily life in his lab—the highs and lows, the drudgery and eureka moments, the agonizing failures. He provides detailed, lucid explanations of the cutting-edge science that enabled Lynch to reveal the inner workings of the molecular machine that manufactures memory. After establishing the building blocks, Lynch then set his sights on uncovering the complicated structure of memory as it is stored across many neurons. Adding practical significance to his groundbreaking work, Lynch discovered a class of drugs that could fix the memory machine when it breaks, drugs that would enhance brain function during the memory process and that hold out the possibility of cures for a wide range of neurological conditions, including Alzheimer’s disease, Parkinson’s disease, and attention deficit hyperactivity disorder. Here is an essential story of science, scientists, and scientific achievement—galvanizing in the telling and thrilling in its far-reaching implications.

    Whether the ailment is a cold, the flu, diabetes, obesity or certain cancers, the likely cause is germs. Our ancient enemies have four families - bacteria, viruses, fungi, and protozoa - and many names: Ebola, E. coli, salmonella, norovirus, gonorrhea. . . Human beings are engaged in a "war on germs," in which we develop ever-more sophisticated weapons and defensive strategies. But it is a war we can never win. Our best plan for staying as healthy is to choose our battles carefully, and try to co-exist with germs as best we can. The Germ Code is a wise, witty and wonderfully readable guide to our relationship with these infinitesimal but infinitely powerful creatures. Microbiologist Jason Tetro takes us outside the lab and shows the enormous influence of germs upon humanity's past, present and future. He unlocks the mysteries of "the germ code" to reveal how these organisms have exploited our every activity and colonized every corner of the earth. From his own research and personal experience, Tetro relates how the most recent flu pandemic happened, how others may have been averted and how more may come about if we aren't careful. He also explains that not every germ is our foe, and offers advice on harnessing the power of good germs to stay healthy and make our planet a better place. The Germ Code is a fascinating journey through an unseen world, an essential manual to living in harmony with germs and a life-enhancing (as well as life-saving!) good read.

    This encouraging change not only has benefited veterans but also provides a blueprint for salvaging America's own deeply troubled healthcare system. "Best Care Anywhere" shows how a government bureaucracy, working with little notice, is setting the standard for best practices and cost reduction while the private sector is lagging in both areas. Author Phillip Longman challenges conventional wisdom by explaining exactly how market forces work to lower quality and raise prices in the healthcare sector, and how U.S. medical practices have a weak basis in science. The book, expanded from a widely praised article in the "Washington Monthly," mixes hard facts with author Philip Longmans' compelling human story of the loss of his wife to cancer. Part manifesto, part moving memoir, "Best Care Anywhere" offers new hope for addressing a major problem of contemporary society that affects all of us.

    Yet you'd have to fly every day for the next 26,000 years to assure yourself of dying in a crash. A leisurely canoe ride is more than 100 times deadlier. Think city streets are unsafe? You're more likely to come to harm in your own home, where every year you stand a 1 in 650 chance of being injured by your bed, mattress, or pillows—and each year 800 Americans die in accidents involving soft furnishings.We live in a world governed by fear, where packets of peanuts "may contain nuts" and children must be ever on the alert to "stranger danger." And yet, life expectancy has never been higher. Crime rates have plunged. Even unintentional injuries are down. So if we're so safe, why are we so afraid?How to Live Dangerously is a hilarious, straight-talking look at the things that terrify us. It considers life's real risks, not to mention the often ridiculous methods we've contrived to keep ourselves "safe." It encourages you to ignore fearmongers and embrace a new kind of freedom, in which we all worry a little less—and live a whole lot more.