The book drives to the heart of the exciting debate on the origins of life and maintenance of order in complex biological systems. It focuses on the concept of self-organization: the spontaneous emergence of order that is widely observed throughout nature Kauffman argues that self-organization plays an important role in the Darwinian process of natural selection. Yet until now no systematic effort has been made to incorporate the concept of self-organization into evolutionary theory. The construction requirements which permit complex systems to adapt are poorly understood, as is the extent to which selection itself can yield systems able to adapt more successfully. This book explores these themes. It shows how complex systems, contrary to expectations, can spontaneously exhibit stunning degrees of order, and how this order, in turn, is essential for understanding the emergence and development of life on Earth. Topics include the new biotechnology of applied molecular evolution, with its important implications for developing new drugs and vaccines; the balance between order and chaos observed in many naturally occurring systems; new insights concerning the predictive power of statistical mechanics in biology; and other major issues. Indeed, the approaches investigated here may prove to be the new center around which biological science itself will evolve. The work is written for all those interested in the cutting edge of research in the life sciences.

    The term “complexity” can be misleading, however, because what makes West’s discoveries so beautiful is that he has found an underlying simplicity that unites the seemingly complex and diverse phenomena of living systems, including our bodies, our cities and our businesses. Fascinated by issues of aging and mortality, West applied the rigor of a physicist to the biological question of why we live as long as we do and no longer. The result was astonishing, and changed science, creating a new understanding of energy use and metabolism: West found that despite the riotous diversity in the sizes of mammals, they are all, to a large degree, scaled versions of each other. If you know the size of a mammal, you can use scaling laws to learn everything from how much food it eats per day, what its heart-rate is, how long it will take to mature, its lifespan, and so on. Furthermore, the efficiency of the mammal’s circulatory systems scales up precisely based on weight: if you compare a mouse, a human and an elephant on a logarithmic graph, you find with every doubling of average weight, a species gets 25% more efficient—and lives 25% longer. This speaks to everything from how long we can expect to live to how many hours of sleep we need. Fundamentally, he has proven, the issue has to do with the fractal geometry of the networks that supply energy and remove waste from the organism's body. West's work has been game-changing for biologists, but then he made the even bolder move of exploring his work's applicability to cities. Cities, too, are constellations of networks and laws of scalability relate with eerie precision to them. For every doubling in a city's size, the city needs 15% less road, electrical wire, and gas stations to support the same population. More amazingly, for every doubling in size, cities produce 15% more patents and more wealth, as well as 15% more crime and disease. This broad pattern lays the groundwork for a new science of cities. Recently, West has applied his revolutionary work on cities and biological life to the business world. This investigation has led to powerful insights into why some companies thrive while others fail. The implications of these discoveries are far-reaching, and are just beginning to be explored. Scale is a thrilling scientific adventure story about the elemental natural laws that bind us together in simple but profound ways. Through the brilliant mind of Geoffrey West, we can envision how cities, companies and biological life alike are dancing to the same simple, powerful tune, however diverse and unrelated they are to each other.From the Hardcover edition.

    In this entertaining and ingenious book, Blastland reveals how in our quest to make the world more understandable, we lose sight of how unexplainable it often is. The result - from GDP figures to medicine - is that experts know a lot less than they think. Filled with compelling stories from economics, genetics, business, and science, The Hidden Half is a warning that an explanation which works in one arena may not work in another. Entertaining and provocative, it will change how you view the world.

    While you could probably learn a lot about each piece, you would have no idea about what the entire picture looks like. This is reductionism -- the idea that to understand the world we only need to study its pieces -- and it is how most social scientists approach their work. In A Crude Look at the Whole, social scientist and economist John H. Miller shows why we need to start looking at whole pictures. For one thing, whether we are talking about stock markets, computer networks, or biological organisms, individual parts only make sense when we remember that they are part of larger wholes. And perhaps more importantly, those wholes can take on behaviors that are strikingly different from that of their pieces. Miller, a leading expert in the computational study of complex adaptive systems, reveals astounding global patterns linking the organization of otherwise radically different structures: It might seem crude, but a beehive's temperature control system can help predict market fluctuations and a mammal's heartbeat can help us understand the "heartbeat" of a city and adapt urban planning accordingly. From enduring racial segregation to sudden stock market disasters, once we start drawing links between complex systems, we can start solving what otherwise might be totally intractable problems. Thanks to this revolutionary perspective, we can finally transcend the limits of reductionism and discover crucial new ideas. Scientifically founded and beautifully written, A Crude Look at the Whole is a powerful exploration of the challenges that we face as a society. As it reveals, taking the crude look might be the only way to truly see.

    In this Very Short Introduction, Peter M. Higgins, a renowned popular-science writer, unravels the world of numbers, demonstrating its richness and providing an overview of all the number types that feature in modern science and mathematics. Indeed, Higgins paints a crystal-clear picture of the number world, showing how the modern number system matured over many centuries, and introducing key concepts such as integers, fractions, real and imaginary numbers, and complex numbers. Higgins sheds light on such fascinating topics as the series of primes, describing how primes are now used to encrypt confidential data on the internet. He also explores the infinite nature of number collections and explains how the so-called real numbers knit together to form the continuum of the number line. Written in the fashion of Higgins' highly popular science paperbacks, Numbers accurately explains the nature of numbers and how so-called complex numbers and number systems are used in calculations that arise in real problems.

    It explains what algorithms do, how they are used, the risks associated with using them, and why governments should be concerned. Important areas arehighlighted, such as Stream Ciphers, block ciphers, public key algorithms, digital signatures, and applications such as e-commerce. This book highlights the explosive impact of cryptography on modern society, with, for example, the evolution of the internet and the introduction of more sophisticatedbanking methods.

    This book describes what schizophrenia is really like, how the illness progresses, and the treatments that have been applied. It also summarizes the most up-to-date knowledge available about the biological bases of this disorder. Finally it attempts to give some idea of what it is like to have schizophrenia and what this disorder tells us about the relationship between mind and brain.

    Growing understanding of the immune system, and especially the creation of immune memory (long lasting protection), which can be harnessed in the design of vaccines, have been major breakthroughs in medicine.In this Very Short Introduction, Paul Klenerman describes the immune system, and how it works in health and disease. In particular he focuses on the human immune system, considering how it evolved, the basic rules that govern its behavior, and the major health threats where it is important. Theimmune system comprises a series of organs, cells and chemical messengers which work together as a team to provide defence against infection. Klenerman discusses these components, the critical signals that trigger them and how they exert their protective effects, including so-called innate immuneresponses, which react very fast to infection, and adaptive immune responses, which have huge diversity and a capacity to recognize and defend against a massive array of micro-organisms. Klenerman also considers what happens when our immune systems fail to be activated effectively, leading toserious infections, problems with inherited diseases, and also HIV/AIDS. At the opposite extreme, as Klenerman shows, an over-exaggerated immune response leads to inflammatory diseases such as Multiple Sclerosis and Rheumatoid Arthritis, as well as allergy and asthma. Finally he looks at the Immunesystem v2.o - how immune therapies and vaccines can be advanced to protect us against the major diseases of the 21st century.ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, andenthusiasm to make interesting and challenging topics highly readable.

    The science of complexity studies how single elements, such as a species or a stock, spontaneously organize into complicated structures like ecosystems and economies; stars become galaxies, and snowflakes avalanches almost as if these systems were obeying a hidden yearning for order. Drawing from diverse fields, scientific luminaries such as Nobel Laureates Murray Gell-Mann and Kenneth Arrow are studying complexity at a think tank called The Santa Fe Institute. The revolutionary new discoveries researchers have made there could change the face of every science from biology to cosmology to economics. M. Mitchell Waldrop's groundbreaking bestseller takes readers into the hearts and minds of these scientists to tell the story behind this scientific revolution as it unfolds.

    Without it, there would be no science or technology. There would be no moral responsibility either, as none of our thoughts would be connected with our actions and none of our actions with any consequences. Nor would we have a system of law because blame resides only in someone having caused injury or damage.Any intervention we make in the world around us is premised on there being causal connections that are, to a degree, predictable. It is causation that is at the basis of prediction and also explanation. This Very Short Introduction introduces the key theories of causation and also the surrounding debates and controversies.About the Series: Oxford's Very Short Introductions series offers concise and original introductions to a wide range of subjects--from Islam to Sociology, Politics to Classics, Literary Theory to History, and Archaeology to the Bible. Not simply a textbook of definitions, each volume in this series provides trenchant and provocative--yet always balanced and complete--discussions of the central issues in a given discipline or field. Every Very Short Introduction gives a readable evolution of the subject in question, demonstrating how the subject has developed and how it has influenced society. Eventually, the series will encompass every major academic discipline, offering all students an accessible and abundant reference library. Whatever the area of study that one deems important or appealing, whatever the topic that fascinates the general reader, the Very Short Introductions series has a handy and affordable guide that will likely prove indispensable.

    Featuring many striking photos, this Very Short Introduction offers a fascinating portrait of the unique world of each planet as well as an illuminating discussion of moons, asteroids, and Trans-Neptunian objects. Leading planetary scientist David A. Rothery, who has chaired the European Space Agency's Mercury surface and composition working group since 2007, gives a stimulating overview of the origin, nature, and evolution of our Solar System, including the controversial issues of what qualifies as a planet, and what conditions are required for a planetary body to support life. He explains how the surfaces of planets and moons have been sculpted by geology, weather, and impacts by meteors and asteroids. Rothery shows how our knowledge has advanced over the centuries, and how it has expanded at a dramatic rate in recent years, going far beyond our Solar System to explore planets orbiting distant stars.

    . . . The subject of complexity is vital and controversial. This book is important and beautifully done."—Stephen Jay Gould"[Complexity] is that curious mix of complication and organization that we find throughout the natural and human worlds: the workings of a cell, the structure of the brain, the behavior of the stock market, the shifts of political power. . . . It is time science . . . thinks about meaning as well as counting information. . . . This is the core of the complexity manifesto. Read it, think about it . . . but don't ignore it."—Ian Stewart, NatureThis second edition has been brought up to date with an essay entitled "On the Edge in the Business World" and an interview with John Holland, author of Emergence: From Chaos to Order.

    First, geologists realized that the continents themselves were drifting across the surface of the globe and that oceans were being created and destroyed. Secondly, pictures of the entire planet were returned from space. Suddenly, the Earth began to be viewed as a single entity; a dynamic, interacting whole, controlled by complex processes we scarcely understood. This Introduction explores emerging geological research and explains how new advances in the understanding of plate tectonics, seismology, and satellite imagery have enabled us to begin to see the Earth as it actually is: dynamic and ever changing.

    And yet it has excused, and even been thought to justify, the most reprehensible crimes. Why should this be? This Very Short Introduction explores this and other puzzling questions. Do we love someone for their virtue, their beauty, or their moral or other qualities? Are love's characteristic desires altruistic or selfish? Are there duties of love? What do the sciences - neuroscience, evolutionary and social psychology, and anthropology - tell us about love? Many of the answers we give to such questions are determined not so much by the facts of human nature as by the ideology of love. Ronald de Sousa considers some of the many paradoxes raised by love, looking at the different kinds of love - affections, affiliation, philia, storage, agape, but focusses on eros, or romantic love. He considers whether our conventional beliefs about love and sex are deeply irrational and argues that alternative conceptions of love and sex, although hard to formulate and live by, may be worth striving for. ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, and enthusiasm to make interesting and challenging topics highly readable.

    But how much do these types of entertainment really tell us about recent scientific discoveries and the latest research into the world of the dinosaur?This is the first book explain how scientists have been able to put together a picture of how dinosaurs looked, what they ate, and how they moved and interacted with each other. Taking a new approach to the subject, David Norman combines different areas of science, such as anatomy, genetics, forensics, and engineering design, to piece together the latest evidence of how animal life evolved on earth. Norman engagingly lays out the history of dinosaur research, from the speculation over ancient myths about dragons, to the latest virtual reality animation sequences and engineering design analysis. He also discusses the role that informed speculation and luck has played in many of the major discoveries.This book is a fantastic introduction for those just beginning to take an interest in dinosaurs and a must-read for true dinosaur-lovers who want to know not just the latest theories and discoveries, but how scientists achieved them.