Why do people—even identical twins reared in the same home—differ so much in personality? Armed with an inquiring mind and insights from evolutionary psychology, Judith Rich Harris sets out to solve the mystery of human individuality.

    We take for granted that we can remember, feel emotion, navigate, empathize, and understand the world around us, but how would our lives change if these abilities were dramatically enhanced--or disappeared overnight?Helen Thomson has spent years traveling the world, tracking down incredibly rare brain disorders. In Unthinkable she tells the stories of nine extraordinary people she encountered along the way. From the man who thinks he's a tiger to the doctor who feels the pain of others just by looking at them to a woman who hears music that’s not there, their experiences illustrate how the brain can shape our lives in unexpected and, in some cases, brilliant and alarming ways.Story by remarkable story, Unthinkable takes us on an unforgettable journey through the human brain. Discover how to forge memories that never disappear, how to grow an alien limb, and how to make better decisions. Learn how to hallucinate and how to make yourself happier in a split second. Find out how to avoid getting lost, how to see more of your reality, even how exactly you can confirm you are alive. Think the unthinkable.

    Diligently treating the drug addicts of Vancouver's notorious Downtown Eastside with sympathy in his heart and legislative reform in mind can't be easy. But Maté never judges. His book is a powerful call-to-arms, both for the decriminalization of drugs and for a more sympathetic and informed view of addiction. As Maté observes, "Those whom we dismiss as 'junkies' are not creatures from a different world, only men and women mired at the extreme end of a continuum on which, here or there, all of us might well locate ourselves." In the Realm of Hungry Ghosts begins by introducing us to many of Dr. Maté's most dire patients who steal, cheat, sell sex, and otherwise harm themselves for their next hit. Maté looks to the root causes of addiction, applying a clinical and psychological view to the physical manifestation and offering some enlightening answers for why people inflict such catastrophe on themselves.Finally, he takes aim at the hugely ineffectual, largely U.S.-led War on Drugs (and its worldwide followers), challenging the wisdom of fighting drugs instead of aiding the addicts, and showing how controversial measures such as safe injection sites are measurably more successful at reducing drug-related crime and the spread of disease than anything most major governments have going. It's not easy reading, but we ignore his arguments at our peril. When it comes to combating the drug trade and the ravages of addiction, society can use all the help it can get. --Kim Hughes

    Immerse yourself in the history of medicine - a colourful story of skill, serendipity, trial and error, moments of genius, and dogged determination.From traditional chinese medicine to today's sophisticated gene therapies and robotic surgery, A Short History of Medicine combines riveting storytelling and beautiful images, historical accounts and lucid explanations, to illuminate the story of medicine through time.Witness early, bloody, anaesthetic-free operations; see the first crude surgical instruments; trace the mapping of the circulatory system; follow the painstaking detective work that led to the decoding of the human genome; and understand the role that potions, cures, therapies, herbal medicines, and drugs have played in the human quest to tame and conquer disease, injury, and death.A Short History of Medicine is an engrossing illustrated history and tale of drama and discovery that celebrates the milestones of medical history across generations and cultures.

    But what is Prozac—a medication, or a mental steroid? A cure for depression, or a drug that changes personality? Reported to turn shy people into social butterflies and to improve work performance, memory, even dexterity, does Prozac work on character rather than illness? Are you using it "cosmetically," to make people more attractive? More energetic, more socially acceptable? And what does it tell us about the nature of character and the mutability of self?

    Sooner or later each of us is obliged, at least for a spell, to identify ourselves as citizens of that other place." Now more than 133 million Americans live with chronic illness, accounting for nearly three-quarters of all health care dollars, and untold pain and disability.There has been an alarming rise in illnesses that defy diagnosis through clinical tests or have no known cure. Millions of people, especially women, with illnesses such as irritable bowel syndrome, chronic pain, and chronic fatigue syndrome face skepticism from physicians and the public alike. And people with diseases as varied as cardiovascular disease, HIV, certain cancers, and type 2 diabetes have been accused of causing their preventable illnesses through their lifestyle choices.We must balance our faith in medical technology with awareness of the limits of science, and confront our throwback beliefs that people who are sick have weaker character than those who are well. Through research and patient narratives, health writer Laurie Edwards explores patient rights, the role of social media in medical advocacy, the origins of our attitudes about chronic illness, and much more. What The Noonday Demon did for people suffering from depression, In the Kingdom of the Sick does for those who are chronically ill.

    We can understand innovations like electricity, agriculture and democracy. The twentieth century, in contrast, gave us relativity, cubism, quantum mechanics, the id, existentialism, Stalin, psychedelics, chaos mathematics, climate change and postmodernism. In order to understand such a disorienting barrage of unfamiliar and knotty ideas, Higgs shows us, we need to shift the framework of our interpretation and view these concepts within the context of a new kind of historical narrative. Instead of looking at it as another step forward in a stable path, we need to look at the twentieth century as a chaotic seismic shift, upending all linear narratives.Higgs invites us along as he journeys across a century “about which we know too much” in order to grant us a new perspective on it. He brings a refreshingly non-academic, eclectic and infectiously energetic approach to his subjects as well as a unique ability to explain how complex ideas connect and intersect—whether he’s discussing Einstein’s theories of relativity, the Beat poets' interest in Eastern thought or the bright spots and pitfalls of the American Dream.

    Joshua Mezrich creates life from loss, transplanting organs from one body to another. In this intimate, profoundly moving work, he illuminates the extraordinary field of transplantation that enables this kind of miracle to happen every day.When Death Becomes Life is a thrilling look at how science advances on a grand scale to improve human lives. Mezrich examines more than one hundred years of remarkable medical breakthroughs, connecting this fascinating history with the inspiring and heartbreaking stories of his transplant patients. Combining gentle sensitivity with scientific clarity, Mezrich reflects on his calling as a doctor and introduces the modern pioneers who made transplantation a reality—maverick surgeons whose feats of imagination, bold vision, and daring risk taking generated techniques and practices that save millions of lives around the world.Mezrich takes us inside the operating room and unlocks the wondrous process of transplant surgery, a delicate, intense ballet requiring precise timing, breathtaking skill, and at times, creative improvisation. In illuminating this work, Mezrich touches the essence of existence and what it means to be alive. Most physicians fight death, but in transplantation, doctors take from death. Mezrich shares his gratitude and awe for the privilege of being part of this transformative exchange as the dead give their last breath of life to the living. After all, the donors are his patients, too.When Death Becomes Life also engages in fascinating ethical and philosophical debates: How much risk should a healthy person be allowed to take to save someone she loves? Should a patient suffering from alcoholism receive a healthy liver? What defines death, and what role did organ transplantation play in that definition? The human story behind the most exceptional medicine of our time, Mezrich’s riveting book is a beautiful, poignant reminder that a life lost can also offer the hope of a new beginning.

    With Humankind, he brings that mentality to bear against one of our most entrenched ideas: namely, that human beings are by nature selfish and self-interested.By providing a new historical perspective of the last 200,000 years of human history, Bregman sets out to prove that we are in fact evolutionarily wired for cooperation rather than competition, and that our instinct to trust each other has a firm evolutionary basis going back to the beginning of Homo sapiens. Bregman systematically debunks our understanding of the Milgram electrical-shock experiment, the Zimbardo prison experiment, and the Kitty Genovese "bystander effect."In place of these, he offers little-known true stories: the tale of twin brothers on opposing sides of apartheid in South Africa who came together with Nelson Mandela to create peace; a group of six shipwrecked children who survived for a year and a half on a deserted island by working together; a study done after World War II that found that as few as 15% of American soldiers were actually capable of firing at the enemy.The ultimate goal of Humankind is to demonstrate that while neither capitalism nor communism has on its own been proven to be a workable social system, there is a third option: giving "citizens and professionals the means (left) to make their own choices (right)." Reorienting our thinking toward positive and high expectations of our fellow man, Bregman argues, will reap lasting success. Bregman presents this idea with his signature wit and frankness, once again making history, social science and economic theory accessible and enjoyable for lay readers.

    Lifton (The Broken Connection; The Life of the Self shows that this medically supervised killing was done in the name of "healing," as part of a racist program to cleanse the Aryan body politic. After the German eugenics campaign of the 1920s for forced sterilization of the "unfit," it was but one step to "euthanasia," which in the Nazi context meant systematic murder of Jews. Building on interviews with former Nazi physicians and their prisoners, Lifton presents a disturbing portrait of careerists who killed to overcome feelings of powerlessness. He includes a chapter on Josef Mengele and one on Eduard Wirths, the "kind, decent" doctor (as some inmates described him) who set up the Auschwitz death machinery. Lifton also psychoanalyzes the German people, scarred by the devastation of World War I and mystically seeking regeneration. This profound study ranks with the most insightful books on the Holocaust.

    Despite her flapping arms and shaking legs, she continued to speak clearly and was able to finish her speech. It was as if she had suddenly become two people: a calm orator and a shuddering wreck. Then the seizures happened again and again. The Shaking Woman tracks Hustvedt’s search for a diagnosis, one that takes her inside the thought processes of several scientific disciplines, each one of which offers a distinct perspective on her paroxysms but no ready solution. In the process, she finds herself entangled in fundamental questions: What is the relationship between brain and mind? How do we remember? What is the self?During her investigations, Hustvedt joins a discussion group in which neurologists, psychiatrists, psychoanalysts, and brain scientists trade ideas to develop a new field: neuropsychoanalysis. She volunteers as a writing teacher for psychiatric in-patients at the Payne Whitney clinic in New York City and unearths precedents in medical history that illuminate the origins of and shifts in our theories about the mind-body problem. In The Shaking Woman, Hustvedt synthesizes her experience and research into a compelling mystery: Who is the shaking woman? In the end, the story she tells becomes, in the words of George Makari, author of Revolution in Mind, “a brilliant illumination for us all.”

    Pink, author of Drive and A Whole New MindA psychiatrist’s stories of his most bizarre cases, The Naked Lady Who Stood on Her Head by Gary Small, M.D., and Gigi Vorgan—co-authors of The Memory Bible—offers a fascinating and highly entertaining look into the peculiarities of the human mind. In the vein of The Man Who Mistook His Wife for a Hat, Awakenings, and the other bestselling works of Oliver Sacks, The Naked Lady Who Stood on Her Head surprises, enthralls, and illuminates as it focuses on medical mysteries that would stump and amaze the brilliant brains on House, M.D.

    Pursuing the idea that human affection could be understood, studied, even measured, Harlow (1905-1981) arrived at his conclusions by conducting research-sometimes beautiful, sometimes horrible-on the primates in his University of Wisconsin laboratory. Paradoxically, his darkest experiments may have the brightest legacy, for by studying "neglect" and its life-altering consequences, Harlow confirmed love's central role in shaping not only how we feel but also how we think. His work sparked a psychological revolution. The more children experience affection, he discovered, the more curious they become about the world: Love makes people smarter. The biography of both a man and an idea, The Measure of Love is a powerful and at times disturbing narrative that will forever alter our understanding of human relationships.

    Professor Irving Kirsch knew this as well as anyone. But, as he discovered during his research, there is a problem with what everyone knows about antidepressant drugs. It isn't true.How did antidepressant drugs gain their reputation as a magic bullet for depression? And why has it taken so long for the story to become public? Answering these questions takes us to the point where the lines between clinical research and marketing disappear altogether.Using the Freedom of Information Act, Kirsch accessed clinical trials that were withheld, by drug companies, from the public and from the doctors who prescribe antidepressants. What he found, and what he documents here, promises to bring revolutionary change to the way our society perceives, and consumes, antidepressants.The Emperor's New Drugs exposes what we have failed to see before: depression is not caused by a chemical imbalance in the brain; antidepressants are significantly more dangerous than other forms of treatment and are only marginally more effective than placebos; and, there are other ways to combat depression, treatments that don't only include the empty promise of the antidepressant prescription.This is not a book about alternative medicine and its outlandish claims. This is a book about fantasy and wishful thinking in the heart of clinical medicine, about the seductions of myth, and the final stubbornness of facts.

    . . If what we want in this moment is insight from this brilliant doctor about pandemics, he wants us to see that they do not occur in isolation. --Carolyn Kellogg, The Boston GlobeIn 2014, Sierra Leone, Liberia, and Guinea suffered the worst epidemic of Ebola in history. The brutal virus spread rapidly through a clinical desert where basic health-care facilities were few and far between. Causing severe loss of life and economic disruption, the Ebola crisis was a major tragedy of modern medicine. But why did it happen, and what can we learn from it?Paul Farmer, the internationally renowned doctor and anthropologist, experienced the Ebola outbreak firsthand--Partners in Health, the organization he founded, was among the international responders. In Fevers, Feuds, and Diamonds, he offers the first substantive account of this frightening, fast-moving episode and its implications. In vibrant prose, Farmer tells the harrowing stories of Ebola victims while showing why the medical response was slow and insufficient. Rebutting misleading claims about the origins of Ebola and why it spread so rapidly, he traces West Africa's chronic health failures back to centuries of exploitation and injustice. Under formal colonial rule, disease containment was a priority but care was not - and the region's health care woes worsened, with devastating consequences that Farmer traces up to the present.This thorough and hopeful narrative is a definitive work of reportage, history, and advocacy, and a crucial intervention in public-health discussions around the world.