Just a half century ago, this idea was revolutionary. In April 1953, James Watson and Francis Crick published in Nature their groundbreaking work revealing the double helix structure of DNA. While this discovery received wide attention from both mainstream media and the academic community, it was just one part of the bigger story in this history of molecular biology. By the mid-1950s, the scientific community confirmed that genes were indeed comprised of DNA; they just needed to crack the genetic code—and the race was on. Life’s Greatest Secret is the full and rich history of this challenge and the characters—many of whom were not biologists—whose work contributed to this grand scientific endeavor: mathematician and father of cybernetics Norbert Wiener, physicist Erwin Schrödinger, information theorist Claude Shannon, and biologists Jacques Monod and Marshall Nirenberg.In Life’s Greatest Secret, science historian and zoologist Matthew Cobb shows that the race to crack the genetic code was mostly a matter of craft—individuals or small groups struggling with ideas and concepts as much as they were with facts, trying to find the right experiment to answer the right questions, even if they didn’t know what the questions were, and finding that, even when the most definitive answer served mostly to reveal more ignorance, whether in 1953, with Watson and Crick, or in 1961, when Nirenberg and Matthaei showed how DNA codes for specific amino acids, and again and again thereafter, or in 2000, with the first publication of a human genome. Each discovery was a leap forward in our understanding of the natural world and our place within in, akin to the discoveries of Galileo and Einstein in the realm of physics, or the publication of Darwin’s On the Origin of Species. And each served to show how much bigger the problem was that anyone had previously imagined, a trend that continues, as Cobb shows, even today, whether we are discussing gene regulation, epigenetics, or GMOs.Life’s Greatest Secret is a story of ideas and of experimentation, of ingenuity, insight, and dead-ends, in the hunt to make the greatest discovery of twentieth century biology. Ultimately, though, this is a story of humans exploring what it is that makes us human.

    Life remains the only way to make life. Are we still missing a vital ingredient in its creation?      Like Richard Dawkins' The Selfish Gene, which provided a new perspective on how evolution works, Life on the Edge alters our understanding of our world's fundamental dynamics. Bringing together first-hand experience at the cutting edge of science with unparalleled gifts of explanation, Jim Al-Khalili and Johnjoe Macfadden reveal that missing ingredient to be quantum mechanics; the phenomena that lie at the heart of this most mysterious of sciences. Drawing on recent ground-breaking experiments around the world, each chapter in Life on the Edge engages by illustrating one of life's puzzles: How do migrating birds know where to go? How do we really smell the scent of a rose? How do our genes copy themselves with such precision? Life on the Edge accessibly reveals how quantum mechanics can answer these probing questions of the universe. Guiding the reader through the rapidly unfolding discoveries of the last few years, Al-Khalili and McFadden communicate the excitement of the explosive new field of quantum biology and its potentially revolutionary applications, while offering insights into the biggest puzzle of all: what is life? As they brilliantly demonstrate in these groundbreaking pages, life exists on the quantum edge.

    That judgment, implausible even to a casual fan, also contradicted the opinion of a growing cadre of neuroscientists who worked in vain to convince the NFL that it was facing a deadly new scourge: A chronic brain disease that was driving an alarming number of players -- including some of the all-time greats -- to madness.League of Denial reveals how the NFL, over a period of nearly two decades, sought to cover up and deny mounting evidence of the connection between football and brain damage.Comprehensively, and for the first time, award-winning ESPN investigative reporters Mark Fainaru-Wada and Steve Fainaru tell the story of a public health crisis that emerged from the playing fields of our 21st century pastime. Everyone knew that football is violent and dangerous. But what the players who built the NFL into a $10 billion industry didn’t know – and what the league sought to shield from them – is that no amount of padding could protect the human brain from the force generated by modern football; that the very essence of the game could be exposing these players to brain damage.In a fast-paced narrative that moves between the NFL trenches, America’s research labs and the boardrooms where the NFL went to war against science, League of Denial examines how the league used its power and resources to attack independent scientists and elevate its own flawed research -- a campaign with echoes of Big Tobacco’s fight to deny the connection between smoking and lung cancer. It chronicles the tragic fates of players like Hall of Fame Pittsburgh Steelers center Mike Webster, who was so disturbed at the time of his death he fantasized about shooting NFL executives; and former Chargers great Junior Seau, whose diseased brain became the target of an unseemly scientific battle between researchers and the NFL. Based on exclusive interviews, previously undisclosed documents and private emails, this is the story of what the NFL knew and when it knew it – questions at the heart of crisis that threatens football, from the highest levels all the way down to Pop Warner.

    Leman offers readers a fascinating and often funny look at how birth order affects personality, marriage and relationships, parenting style, career, and children.

    Language is humanity's most spectacular open-source project, and the internet is making our language change faster and in more interesting ways than ever before. Internet conversations are structured by the shape of our apps and platforms, from the grammar of status updates to the protocols of comments and @replies. Linguistically inventive online communities spread new slang and jargon with dizzying speed. What's more, social media is a vast laboratory of unedited, unfiltered words where we can watch language evolve in real time.Even the most absurd-looking slang has genuine patterns behind it. Internet linguist Gretchen McCulloch explores the deep forces that shape human language and influence the way we communicate with one another. She explains how your first social internet experience influences whether you prefer "LOL" or "lol," why ~sparkly tildes~ succeeded where centuries of proposals for irony punctuation had failed, what emoji have in common with physical gestures, and how the artfully disarrayed language of animal memes like lolcats and doggo made them more likely to spread.Because Internet is essential reading for anyone who's ever puzzled over how to punctuate a text message or wondered where memes come from. It's the perfect book for understanding how the internet is changing the English language, why that's a good thing, and what our online interactions reveal about who we are.

    It is a waste product and a commodity pricier than oil. It can save lives and transmit deadly infections. Each one of us has roughly nine pints of it, yet many don’t even know their own blood type. And for all its ubiquity, the few tablespoons of blood discharged by 800 million women are still regarded as taboo; menstruation is perhaps the single most demonized biological event.Rose George, author of The Big Necessity, is renowned for her intrepid work on topics that are invisible but vitally important. In Nine Pints, she takes us from ancient practices of bloodletting to modern “hemovigilance” teams that track blood-borne diseases. She introduces Janet Vaughan, who set up the world’s first system of mass blood donation during the Blitz, and Arunachalam Muruganantham, known as “Menstrual Man” for his work on sanitary pads for developing countries. She probes the lucrative business of plasma transfusions, in which the U.S. is known as the “OPEC of plasma.” And she looks to the future, as researchers seek to bring synthetic blood to a hospital near you.Spanning science and politics, stories and global epidemics, Nine Pints reveals our life's blood in an entirely new light.

    Now Wright attempts something even more ambitious: explaining the direction of evolution and human history–and discerning where history will lead us next.In Nonzero: The Logic of Human Destiny, Wright asserts that, ever since the primordial ooze, life has followed a basic pattern. Organisms and human societies alike have grown more complex by mastering the challenges of internal cooperation. Wright's narrative ranges from fossilized bacteria to vampire bats, from stone-age villages to the World Trade Organization, uncovering such surprises as the benefits of barbarian hordes and the useful stability of feudalism. Here is history endowed with moral significance–a way of looking at our biological and cultural evolution that suggests, refreshingly, that human morality has improved over time, and that our instinct to discover meaning may itself serve a higher purpose. Insightful, witty, profound, Nonzero offers breathtaking implications for what we believe and how we adapt to technology's ongoing transformation of the world.From the Trade Paperback edition.

    But how did we acquire the most advanced form of communication on Earth? Daniel L. Everett, a “bombshell” linguist and “instant folk hero” (Tom Wolfe, Harper’s), provides in this sweeping history a comprehensive examination of the evolutionary story of language, from the earliest speaking attempts by hominids to the more than seven thousand languages that exist today.Although fossil hunters and linguists have brought us closer to unearthing the true origins of language, Daniel Everett’s discoveries have upended the contemporary linguistic world, reverberating far beyond academic circles. While conducting field research in the Amazonian rainforest, Everett came across an age-old language nestled amongst a tribe of hunter-gatherers. Challenging long-standing principles in the field, Everett now builds on the theory that language was not intrinsic to our species. In order to truly understand its origins, a more interdisciplinary approach is needed—one that accounts as much for our propensity for culture as it does our biological makeup.Language began, Everett theorizes, with Homo Erectus, who catalyzed words through culturally invented symbols. Early humans, as their brains grew larger, incorporated gestures and voice intonations to communicate, all of which built on each other for 60,000 generations. Tracing crucial shifts and developments across the ages, Everett breaks down every component of speech, from harnessing control of more than a hundred respiratory muscles in the larynx and diaphragm, to mastering the use of the tongue. Moving on from biology to execution, Everett explores why elements such as grammar and storytelling are not nearly as critical to language as one might suspect.In the book’s final section, Cultural Evolution of Language, Everett takes the ever-debated “language gap” to task, delving into the chasm that separates “us” from “the animals.” He approaches the subject from various disciplines, including anthropology, neuroscience, and archaeology, to reveal that it was social complexity, as well as cultural, physiological, and neurological superiority, that allowed humans—with our clawless hands, breakable bones, and soft skin—to become the apex predator.How Language Began ultimately explains what we know, what we’d like to know, and what we likely never will know about how humans went from mere communication to language. Based on nearly forty years of fieldwork, Everett debunks long-held theories by some of history’s greatest thinkers, from Plato to Chomsky. The result is an invaluable study of what makes us human.

    Coated in red dust, the terrain is bewilderingly empty. And yet multiple spacecraft are circling Mars, sweeping over Terra Sabaea, Syrtis Major, the dunes of Elysium, and Mare Sirenum—on the brink, perhaps, of a staggering find, one that would inspire humankind as much as any discovery in the history of modern science.In this beautifully observed, deeply personal book, Georgetown scientist Sarah Stewart Johnson tells the story of how she and other researchers have scoured Mars for signs of life, transforming the planet from a distant point of light into a world of its own.Johnson’s fascination with Mars began as a child in Kentucky, turning over rocks with her father and looking at planets in the night sky. She now conducts fieldwork in some of Earth’s most hostile environments, such as the Dry Valleys of Antarctica and the salt flats of Western Australia, developing methods for detecting life on other worlds. Here, with poetic precision, she interlaces her own personal journey—as a female scientist and a mother—with tales of other seekers, from Percival Lowell, who was convinced that a utopian society existed on Mars, to Audouin Dollfus, who tried to carry out astronomical observations from a stratospheric balloon. In the process, she shows how the story of Mars is also a story about Earth: This other world has been our mirror, our foil, a telltale reflection of our own anxieties and yearnings.Empathetic and evocative, The Sirens of Mars offers an unlikely natural history of a place where no human has ever set foot, while providing a vivid portrait of our quest to defy our isolation in the cosmos.

    Starting once again with fossils, he turns his gaze skyward, showing us how the entirety of the universe’s fourteen-billion-year history can be seen in our bodies. As he moves from our very molecular composition (a result of stellar events at the origin of our solar system) through the workings of our eyes, Shubin makes clear how the evolution of the cosmos has profoundly marked our own bodies. Fully illustrated with black and white drawings.

    He was one of the leading pioneers of the greatest revolution in twentieth-century science: quantum mechanics. The youngest theoretician ever to win the Nobel Prize for Physics, he was also pathologically reticent, strangely literal-minded and legendarily unable to communicate or empathize. Through his greatest period of productivity, his postcards home contained only remarks about the weather.Based on a previously undiscovered archive of family papers, Graham Farmelo celebrates Dirac's massive scientific achievement while drawing a compassionate portrait of his life and work. Farmelo shows a man who, while hopelessly socially inept, could manage to love and sustain close friendship.The Strangest Man is an extraordinary and moving human story, as well as a study of one of the most exciting times in scientific history.'A wonderful book . . . Moving, sometimes comic, sometimes infinitely sad, and goes to the roots of what we mean by truth in science.' Lord Waldegrave, Daily Telegraph

    More than two centuries after Euler's death, it is still regarded as a conceptual diamond of unsurpassed beauty. Called Euler's identity or God's equation, it includes just five numbers but represents an astonishing revelation of hidden connections. It ties together everything from basic arithmetic to compound interest, the circumference of a circle, trigonometry, calculus, and even infinity. In David Stipp's hands, Euler's identity formula becomes a contemplative stroll through the glories of mathematics. The result is an ode to this magical field.

    Writing with dazzling elegance and clarity, he retraces the steps that have led modern scientists from relativity and quantum mechanics to the notion of superstrings and the idea that our universe may coexist with others.But Weinberg asks as many questions as he answers, among them: Why does each explanation of the way nature works point to the other, deeper explanations? Why are the best theories not only logical but beautiful? And what implications will a final theory have for our philosophy and religious faith?Intellectually daring, rich in anecdote and aphorism, Dreams of a Final Theory launches us into a new cosmos and helps us make sense of what we find there.“This splendid book is as good reading about physics and physicists as this reviewer can name…clear, honest, and brilliantly instructive.”—Philip Morrison, Scientific American

    Extremely elusive and difficult to pin down, neutrinos are not unlike the brilliant and eccentric scientists who doggedly pursue them.In Neutrino Hunters, the renowned astrophysicist and award-winning writer Ray Jayawardhana takes us on a thrilling journey into the shadowy world of neutrinos and the colorful lives of those who seek them. Demystifying particle science along the way, Jayawardhana tells a detective story with cosmic implications—interweaving tales of the sharp-witted theorist Wolfgang Pauli; the troubled genius Ettore Majorana; the harbinger of the atomic age Enrico Fermi; the notorious Cold War defector Bruno Pontecorvo; and the dynamic dream team of Marie and Pierre Curie. Then there are the scientists of today who have caught the neutrino bug, and whose experimental investigations stretch from a working nickel mine in Ontario to a long tunnel through a mountain in central Italy, from a nuclear waste site in New Mexico to a bay on the South China Sea, and from Olympic-size pools deep underground to a gigantic cube of Antarctic ice—called, naturally, IceCube.As Jayawardhana recounts a captivating saga of scientific discovery and celebrates a glorious human quest, he reveals why the next decade of neutrino hunting will redefine how we think about physics, cosmology, and our lives on Earth.

    In a spirited tour across continents and cultures, Adam Rogers takes us from bourbon country to the world’s top gene-sequencing labs, introducing us to the bars, barflies, and evolving science at the heart of boozy technology. He chases the physics, biology, chemistry, and metallurgy that produce alcohol, and the psychology and neurobiology that make us want it. If you’ve ever wondered how your drink arrived in your glass, or what it will do to you, Proof makes an unparalleled drinking companion.