Prusiner received a Nobel Prize, the world's most prestigious award for achievement in physiology or medicine. That he was the sole recipient of the award for the year was entirely appropriate, for his struggle to identify the agent responsible for ravaging the brains of animals suffering from scrapie and mad cow disease, and of humans with Creutzfeldt-Jakob disease, had been waged largely alone and in some cases in the face of strenuous disagreement.   In this book, Prusiner tells the remarkable story of his discovery of prions—infectious proteins that replicate and cause disease but surprisingly contain no genetic material—and reveals how superb and meticulous science is actually practiced using talented teams of researchers who persevere. He recounts the frustrations and rewards of years of research and offers fascinating portraits of his peers as they raced to discover the causes of fatal brain diseases. Prusiner’s hypothesis, once considered heresy, now stands as accepted science and the basis for developing diagnoses and eventual cures. He closes with a meditation on the legacy of his discovery: What will it take to cure Alzheimer’s, Parkinson’s, Lou Gehrig’s and other devastating diseases of the brain?

    As singular and strange as some of the weapons we encounter on these pages are, we learn that similar factors set their evolution in motion. Emlen uses these patterns to draw parallels to the way we humans develop and employ our own weapons, and have since battle began. He looks at everything from our armor and camouflage to the evolution of the rifle and the structures human populations have built across different regions and eras to protect their homes and communities. With stunning black and white drawings and gorgeous color illustrations of these concepts at work, Animal Weapons brings us the complete story of how weapons reach their most outsized, dramatic potential, and what the results we witness in the animal world can tell us about our own relationship with weapons of all kinds.

    The latex of papaver somniferum is a bringer of sleep, of pleasurable lethargy, of relief from pain—and hugely addictive. A commodity without rival, it is renewable, easy to extract, transport, and refine, and subject to an insatiable global demand.No other substance in the world is as simple to produce or as profitable. It is the basis of a gargantuan industry built upon a shady underworld, but ultimately it is an agricultural product that lives many lives before it reaches the branded blister packet, the intravenous drip, or the scorched and filthy spoon. Many of us will end our lives dependent on it.In Milk of Paradise, acclaimed cultural historian Lucy Inglis takes readers on an epic journey from ancient Mesopotamia to modern America and Afghanistan, from Sanskrit to pop, from poppy tears to smack, from morphine to today’s synthetic opiates. It is a tale of addiction, trade, crime, sex, war, literature, medicine, and, above all, money. And, as this ambitious, wide-ranging, and compelling account vividly shows, the history of opium is our history and it speaks to us of who we are.

    In this collection some of the finest names in contemporary travel writing reveal the perils and pleasures of exchanging the familiar for the foreign.Isabel Allende discovers love and paradise in California, Pico Iyer finds home in Japan amidst the alien and indecipherable, and a dank barge on the Seine opens up a new side of Paris for Mort Rosenblum.Revealing the flip side to the dream, relocating to the juicy heart of New York proves fiery for Lily Brett, Chris Stewart is frightened for his life in Andalucia, and the plumbing in William Dalrymple’s rooftop Delhi flat is held to ransom by his water-conserving landlady.Original Stories by:Isabel Allende, Karl Taro Greenfeld, Jan Morris, Rolf Potts, Mort Rosenbaum, Jeffrey Taylor, Errol Trzebinski, Simon Winchester.Selected writings by:Vida Adamoli, Lily Brett, Tony Cohan, William Dalrymple, Amitav Ghos, Carla Grissmann, James Hamilton-Paterson, Annie Hawes, Peter Hesller, Pico Iyer, Alex Kerr, Frances Mayes, Peter Mayle, Tim Parks, Chris Stewart, Emma Tennant, Paul Theroux, Nial Williams and Christine Breen.Home thoughts from Abroad --A Home in Paradise --The Alien Home, From the Global Soul --Tiwarik and Kansulay, from Playiing with Water --February, from A Year in Provence --Festina Tarde (Make Haste Slowly), from Under the Tuscan Sun --from City of Djinns --from O come Ye Back to Ireland --Digging Mr Benny's Dead Uncle --Troppo Gentile, from Italian Neighbours --At Home on the Seine --Tenmangu, from Lost Japan --from Dinner of Herbs --A Co-op Building, from New york --A House in the Casbah --The Visit, from On Mexican Time --The Year Brunetto II Piccolo Fell in Love, from La Bella Vita --from Extra Virgin --Waiting for juan, from a Parrot in the Pepper Tree --Lataifa, From In an Antique Land --Aloft in Paris --Chinese Life, from River Town --A Love-Scene after Work: Writing in the Tropics, from Sunrise with Seamonsters --from A House in Corfu --Barefoot at Shanzu --Coming Home in Massachusetts

    Book 7: BISHOP’S QUEEN A reality star with an obsessive stalker finds herself under the protection of an ex-boyfriend from a tragic past who is her opposite in every way.Book 8: LOCKE AND KEY A military operative must rescue a journalist whom he blames for the murder of his teammates years ago.Book 9: JAX A former Navy SEAL and the daughter of a notorious motorcycle gangster partner to dismantle a drug cartel's partnership with the CIA.Each love story can be read as an action-packed, steamy standalone romance novel. No cliffhangers!

    One woman alone against the world. Young, beautiful, and yearning for love, Heather Bancroft meets the "perfect" man...and is lured into a game in which she begins to make more money than she ever imagined. Betrayed by her own innocence, she loses all that is dear to her and discovers that she has been mercilessly used. Defeated and broken, but surviving with sheer persistence and ingenuity, Heather emerges from her trying ordeal, determined to punish the ruthless man who destroyed her life. Her thirst for revenge takes her halfway around the globe, to the turquoise waters of the Mediterranean, where her nemesis secludes himself in obscene wealth that he's gained from the financial ruin of others. Heather is playing for the highest stakes in a lethal game. Only one man loves her - he's handsome, confident, and just as determined as she is. Only one man can stop her - a criminal mastermind who is intent on her destruction.

    He’s turned into a bug–again. Eric and Julie hope someone in Droon can help. Princess Keeah thinks there might be a cure in the City in the Clouds. Too bad the friends only have one day before the city disappears! The Great Ice BattleBrrr! Jaffa City is under a spell of ice and snow. Even Galen the wizard is frozen solid! Eric, Julie, Neal, and Princess Keeah have to figure out a way to break Lord Sparr's curse. But they better hurry or they might get frozen, too.The Sleeping Giant of GollLord Sparr has found a new weapon to use against the city of Droon. He’s woken up a mean old giant that will now obey his every command! It’s a good thing Eric, Julie, and Neal are around to help their friends try to stop Lord Sparr. It’s a giant job, but somebody’s got to do it!

    This book provides the first complete identification guides to the birds of this teeming tropical paradise. It gives descriptions of 820 regional species, illustrated in 88 specially commissioned color plates accompanied by notes detailing distinctive features and habitats. Entries cover nomenclature, plumage, markings, voice, global range, distribution and regional status, habits, and diet. The main text gives practical information on where to find many exotic species, citing major birdwatching locations. Introductory chapters discuss habitats, climate, land-use, and conservation concerns. Professional ornithologists and amateur bird watchers alike will find this the indispensable bird guide for eastern Malaysia and western Indonesia for many years to come. It is also an unrivalled source of information for casual travellers and ecotourists.

     Fate and fortune. Power and passion. What does it take to be the queen of a kingdom when you're only seventeen?Maya is cursed. With a horoscope that promises a marriage of Death and Destruction, she has earned only the scorn and fear of her father's kingdom. Content to follow more scholarly pursuits, her whole world is torn apart when her father, the Raja, arranges a wedding of political convenience to quell outside rebellions. Soon Maya becomes the queen of Akaran and wife of Amar. Neither roles are what she expected: As Akaran's queen, she finds her voice and power. As Amar's wife, she finds something else entirely: Compassion. Protection. Desire...But Akaran has its own secrets -- thousands of locked doors, gardens of glass, and a tree that bears memories instead of fruit. Soon, Maya suspects her life is in danger. Yet who, besides her husband, can she trust? With the fate of the human and Otherworldly realms hanging in the balance, Maya must unravel an ancient mystery that spans reincarnated lives to save those she loves the most. . .including herself.A lush and vivid story that is steeped in Indian folklore and mythology. The Star-Touched Queen is a novel that no reader will soon forget.

    Though the world was arguably simpler back then, it was in many ways much more dangerous. Not coincidentally, the binary brain was highly adept at detecting risk: the ability to analyze threats and respond to changes in the sensory environment--a drop in temperature, the crack of a branch--was essential to our survival as a species.Since then, the world has evolved--but we, for the most part, haven't. Confronted with a panoply of shades of gray, our brains have a tendency to "force quit: " to sort the things we see, hear, and experience into manageable but simplistic categories. We stereotype, pigeon-hole, and, above all, draw lines where in reality there are none. In our modern, interconnected world, it might seem like we are ill-equipped to deal with the challenges we face--that living with a binary brain is like trying to navigate a teeming city center with a map that shows only highways.In Black-and-White Thinking, the renowned psychologist Kevin Dutton pulls back the curtains of the mind to reveal a new way of thinking about a problem as old as humanity itself. While our instinct for categorization often leads us astray, encouraging polarization, rigid thinking, and sometimes outright denialism, it is an essential component of the mental machinery we use to make sense of the world. Simply put, unless we perceived our environment as a chessboard, our brains wouldn't be able to play the game.Using the latest advances in psychology, neuroscience, and evolutionary biology, Dutton shows how we can optimize our tendency to categorize and fine-tune our minds to avoid the pitfalls of too little, and too much, complexity. He reveals the enduring importance of three "super categories"--fight or flight, us versus them, and right or wrong--and argues that they remain essential to not only convincing others to change their minds but to changing the world for the better. Black-and-White Thinking is a scientifically informed wake-up call for an era of increasing extremism and a thought-provoking, uplifting guide to training our gray matter to see that gray really does matter.

    The political and socio-economic developments that have influenced the growth of modern India have been dealt with in independent chapters.

    

    But as biologist Beth Shapiro argues in Life as We Made It, this phenomenon isn’t new. Humans have been reshaping the world around us for ages, from early dogs to modern bacteria modified to pump out insulin. Indeed, she claims, reshaping nature—resetting the course of evolution, ours and others’—is the essence of what our species does. In exploring our evolutionary and cultural history, Shapiro finds a course for the future. If we have always been changing nature to help us survive and thrive, then we need to avoid naive arguments about how we might destroy it with our meddling, and instead ask how we can meddle better. Brilliant and insightful, Life as We Made It is an essential book for the decades to come.

    Scientists and government officials insisted, for a year and a half, that the virus had a natural origin, ridiculing anyone who dared contradict this view. Tech giants swept the internet, censoring and silencing debate in the most extreme fashion. Yet it is undeniable that a secretive facility in Wuhan was immersed in genetically manipulating bat-coronaviruses in perilous experiments. And as soon as the news of an outbreak in Wuhan leaked, the Chinese military took control and gagged all laboratory insiders.Part-thriller, part-expose, What Really Happened in Wuhan is a ground-breaking investigation from leading journalist Sharri Markson into the origins of Covid-19, the cover-ups, the conspiracies and the classified research. It features never-before-seen primary documents exposing China's concealment of the virus, fresh interviews with whistleblower doctors in Wuhan and crucial eyewitness accounts that dismantle what we thought we knew about when the outbreak hit.With unprecedented access to Washington insiders, Markson takes you inside the White House, with senior Trump lieutenants revealing first-hand accounts of fiery Oval Office clashes and new stories of compromised government advisors and censored scientists.Bravely reported and chillingly laid out, Markson brings to light the stories of the pandemic from the people on the ground: the scientists and national security officials who raised uncomfortable truths and were labelled conspiracy theorists, until government agencies began to suspect they might have been right all along. These brave individuals persisted through bruising battles and played a crucial role in investigating the origins of Covid-19 to finally, in this book, bring us closer to the truth of what really happened in Wuhan.

    In this mind-bending book, an esteemed neuroscientist explains why perfectionism is pointless--and argues that mistakes, missteps, and flaws are the keys to success.