Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings? A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.

    Smallpox. Incurable and horrifying Ebola-related fevers. For two decades, while a fearful world prepared for nuclear winter, an elite team of Russian bioweaponeers began to till a new killing field: a bleak tract sown with powerful seeds of mass destruction—by doctors who had committed themselves to creating a biological Armageddon. Biohazard is the never-before-told story of Russia’s darkest, deadliest, and most closely guarded Cold War secret.   No one knows more about Russia’s astounding experiments with biowarfare than Ken Alibek. Now the mastermind behind Russia’s germ warfare effort reveals two decades of shocking breakthroughs . . . how Moscow’s leading scientists actually reengineered hazardous microbes to make them even more virulent . . . the secrets behind the discovery of an invisible, untraceable new class of biological agents just right for use in political assassinations . . . the startling story behind Russia’s attempt to turn a sample of the AIDS virus into the ultimate bioweapon. And in a chilling work of real-world intrigue, Biohazard offers us all a rare glimpse into a shadowy scientific underworld where doctors manufacture mass destruction, where witnesses to errors are silenced forever, and where ground zero is closer than we ever dared believe.

    The book is an analysis of physical suffering and its relation to the numerous vocabularies and cultural forces--literary, political, philosophical, medical, religious--that confront it. Elaine Scarry bases her study on a wide range of sources: literature and art, medical case histories, documents on torture compiled by Amnesty International, legal transcripts of personal injury trials, and military and strategic writings by such figures as Clausewitz, Churchill, Liddell Hart, and Kissinger, She weaves these into her discussion with an eloquence, humanity, and insight that recall the writings of Hannah Arendt and Jean-Paul Sartre. Scarry begins with the fact of pain's inexpressibility. Not only is physical pain enormously difficult to describe in words--confronted with it, Virginia Woolf once noted, "language runs dry"--it also actively destroys language, reducing sufferers in the most extreme instances to an inarticulate state of cries and moans. Scarry analyzes the political ramifications of deliberately inflicted pain, specifically in the cases of torture and warfare, and shows how to be fictive. From these actions of "unmaking" Scarry turns finally to the actions of "making"--the examples of artistic and cultural creation that work against pain and the debased uses that are made of it. Challenging and inventive, The Body in Pain is landmark work that promises to spark widespread debate.

    In a book of unprecedented scope, McGilchrist draws on a vast body of recent brain research, illustrated with case histories, to reveal that the difference is profound—not just this or that function, but two whole, coherent, but incompatible ways of experiencing the world. The left hemisphere is detail oriented, prefers mechanisms to living things & is inclined to self-interest. The right hemisphere has greater breadth, flexibility & generosity. This division helps explain the origins of music & language, & casts new light on the history of philosophy, as well as on some mental illnesses. The 2nd part of the book takes a journey thru the history of Western culture, illustrating the tension between these two worlds as revealed in the thought & belief of thinkers & artists, from Aeschylus to Magritte. He argues that, despite its inferior grasp of reality, the left hemisphere is increasingly taking precedence in the modern world, with potentially disastrous consequences.List of IllustrationsAcknowledgmentsIntroductionAsymmetry and the brain --What do the two hemispheres 'do'? --Language, truth and music --The nature of the two worlds --The primacy of the right hemisphere --The triumph of the left hemisphere --Imitation and the evolution of culture --The ancient world --The Renaissance and the Reformation --The Enlightenment --Romanticism and the Industrial Revolution --The modern and post-modern worldsConclusionNotes BibliographyIndex

    Instead, follow the data: In seventy-five jaw-dropping graphs, Pinker shows that life, health, prosperity, safety, peace, knowledge, and happiness are on the rise, not just in the West, but worldwide. This progress is not the result of some cosmic force. It is a gift of the Enlightenment: the conviction that reason and science can enhance human flourishing.Far from being a naïve hope, the Enlightenment, we now know, has worked. But more than ever, it needs a vigorous defense. The Enlightenment project swims against currents of human nature–tribalism, authoritarianism, demonization, magical thinking–which demagogues are all too willing to exploit. Many commentators, committed to political, religious, or romantic ideologies, fight a rearguard action against it. The result is a corrosive fatalism and a willingness to wreck the precious institutions of liberal democracy and global cooperation.With intellectual depth and literary flair, Enlightenment Now makes the case for reason, science, and humanism: the ideals we need to confront our problems and continue our progress.

    Gina Rippon finally challenges this damaging myth by showing how the science community has engendered bias and stereotype by rewarding studies that show difference rather than sameness. Drawing on cutting edge research in neuroscience and psychology, Rippon presents the latest evidence which she argues, finally proves that brains are like mosaics comprised of both male and female components, and that they remain plastic, adapting throughout the course of a person’s life. Discernable gender identities, she asserts, are shaped by society where scientific misconceptions continue to be wielded and perpetuated to the detriment of our children, our own lives, and our culture.

    Krause is a pioneer in the revolutionary new science of archaeogenetics, archaeology augmented by revolutionary DNA sequencing technology, which has allowed scientists to uncover a new version of human history reaching back more than 100,000 years. Using this technology to re-examine human bones from the distant past, Krause has been able to map not only the genetic profiles of the dead, but also their ancient journeys.In this concise narrative he tells us their long-forgotten stories of migration and intersection. It's well known that many human populations carry genetic material from Neanderthals; but, as Krause and his colleagues discovered, we also share DNA with a newly uncovered human form, the Denisovans. We know now that a wave of farmers from Anatolia migrated into Europe 8,000 years ago, essentially displacing the dark-skinned, blue-eyed hunter-gatherers who preceded them. The farmer DNA is one of the core genetic components of contemporary Europeans and European Americans. Though the first people to cross into North and South America have long been assumed to be primarily of East Asian descent, we now know that they also share DNA with contemporary Europeans and European Americans. Genetics has an unfortunate history of smuggling in racist ideologies, but our most cutting-edge science tells us that genetic categories in no way reflect national borders.Krause vividly introduces us to prehistoric cultures such as the Aurignacians, innovative artisans who carved animals, people, and even flutes from bird bones more than 40,000 years ago; the Varna, who buried their loved ones with gold long before the Pharaohs of Egypt; and the Gravettians, big-game hunters who were Europe's most successful early settlers until they perished in the ice age. This informed retelling of the human epic confirms that immigration and genetic mingling have always defined our species and that who we are is a question of culture not genetics.

    Drawing on anecdotes from science, economics, history, politics and philosophy, Matt Ridley’s wide-ranging, highly opinionated opus demolishes conventional assumptions that major scientific and social imperatives are dictated by those on high, whether in government, business, academia, or morality. On the contrary, our most important achievements develop from the bottom up. Patterns emerge, trends evolve. Just as skeins of geese form Vs in the sky without meaning to, and termites build mud cathedrals without architects, so brains take shape without brain-makers, learning can happen without teaching and morality changes without a plan.Although we neglect, defy and ignore them, bottom-up trends shape the world. The growth of technology, the sanitation-driven health revolution, the quadrupling of farm yields so that more land can be released for nature—these were largely emergent phenomena, as were the Internet, the mobile phone revolution, and the rise of Asia. Ridley demolishes the arguments for design and effectively makes the case for evolution in the universe, morality, genes, the economy, culture, technology, the mind, personality, population, education, history, government, God, money, and the future.

    Webb. The Man Who Ran the Moon explores a time when Webb and an elite group of charismatic business associates took control of America's Apollo moon project, sometimes with disturbing results. In 1967, NASA was rocked by disaster and Apollo was grounded. Webb was savaged in a Congressional investigation. Not just a matter of broken hardware, there were accusations of corruption at the heart of America's space effort. Some of Webb's political allies had been caught up in the biggest scandal ever to hit Washington prior to Watergate. The backwash unfairly tainted NASA's chief. By the time of the first triumphant lunar landing, Webb had resigned and his name had all but been forgotten. But he's the man who got us to the moon, and the power base he forged in the 1960s has kept NASA on a solid footing to this day. Washington insiders now acknowledge Webb as one of the greatest leaders in modern American history. No space boss since his time has wielded so much power and such a powerful story.

    But all too often the full picture of change is obstructed by dense data sets and particular catastrophes. Struggling with this obscurity in her role as an editor at Nature, Gaia Vince decided to travel the world and see for herself what life is really like for people on the frontline of this new reality. What she found was a number people doing the most extraordinary things.During her journey she finds a man who is making artificial glaciers in Nepal along with an individual who is painting mountains white to attract snowfall; take the electrified reefs of the Maldives; or the man who's making islands out of rubbish in the Caribbean. These are ordinary people who are solving severe crises in crazy, ingenious, effective ways. While Vince does not mince words regarding the challenging position our species is in, these wonderful stories, combined with the new science that underpins Gaia's expertise and research, make for a persuasive, illuminating — and strangely hopeful — read on what the Anthropocene means for our future.

    In this gripping account, David Quammen takes the reader along on this astonishing quest to learn how, where from, and why these diseases emerge and asks the terrifying question: What might the next big one be?

    Applying the same objective criteria to legal and illegal substances, an argument is made that legality is not a clear measure for harm. Tackling a variety of questions, such as Which is more harmful—Ecstasy or alcohol? Can addiction be cured? and Does the "War on Drugs" have serious unintended effects that can hurt children?, this analysis equips readers with the ability to make educated decisions regarding drugs both personally and in their communities. Broadening the scope of the discussion, a framework is explored for formulating national drug policies that will minimize a myriad of harms—social, medical, criminal, financial, and environmental.

    Ed Strimlan is a doctor who never got to practice medicine. Instead he discovers how people died. Mike Chichwak is a stolid ex-paramedic, respected around the office for his compassion and doggedness. Tiffani Hunt is twenty-one, a single mother who questions whether she wants to spend her nights around dead bodies.All three deputy coroners share one trait: a compulsive curiosity. A good thing too because any observation at a death scene can prove meaningful. A bag of groceries standing on a kitchen counter, the milk turning sour. A broken lamp lying on the carpet of an otherwise tidy living room. When they approach a corpse, the investigators consider everything. Is the victim face-up or down? How stiff are the limbs? Are the hands dirty or clean? By the time they bag the body and load it into the coroner's wagon, Tiffani, Ed, and Mike have often unearthed intimate details that are unknown even to the victim's family and friends.The intrigues of investigating death help make up for the bad parts of the job. There are plenty of burdens--grief-stricken families, decomposed bodies, tangled local politics, and gore. And maybe worst of all is the ever-present reminder of mortality and human frailness.Deadhouse also chronicles the evolution of forensic medicine, from early rituals performed over corpses found dead to the controversial advent of modern forensic pathology. It explains how pathologists "read" bullet wounds and lacerations, how someone dies from a drug overdose or a motorcycle crash or a drowning, and how investigators uncover the clues that lead to the truth.

    Drawing on momentous (yet dimly remembered) historical epidemics, contemporary analyses, and cutting-edge research from a range of scientific disciplines, bestselling author, physician, sociologist, and public health expert Nicholas A. Christakis explores what it means to live in a time of plague—an experience that is paradoxically uncommon to the vast majority of humans who are alive, yet deeply fundamental to our species.Unleashing new divisions in our society as well as opportunities for cooperation, this 21st-century pandemic has upended our lives in ways that will test, but not vanquish, our already frayed collective culture. Featuring new, provocative arguments and vivid examples ranging across medicine, history, sociology, epidemiology, data science, and genetics, Apollo's Arrow envisions what happens when the great force of a deadly germ meets the enduring reality of our evolved social nature.

    Scientists in every field are desperate to explain this epidemic and stave off a modern health disaster. But what’s to blame? Carbs, fat or sugar? Gut microbes or genes? Laziness or poverty?In The Truth About Fat, Anthony Warner scrutinises the explanations of experts in every field, speaks to those who dedicate their lives to helping obese people and to others who live with their own larger bodies every day. As he lays out the best evidence available, he rails against quack theories preying on the desperate and considers whether we are blaming our own bodies for other people's ignorance and cruelty. What remains is the unvarnished truth about one of the great preoccupations of our age.