Its job is to protect us from cancer. This gene--known simply as p53--constantly scans our cells to ensure that when they grow and divide as part of the routine maintenance of our bodies, they do so without mishap. If a cell makes a mistake in copying its DNA during the process of division, p53 stops it in its tracks, sending in the repair team before allowing the cell to carry on dividing. If the mistake is irreparable and the rogue cell threatens to grow out of control (as happens in cancer), p53 commands the cell to commit suicide. Cancer cannot develop unless p53 itself is damaged or handicapped by some other fault in the system. Not surprisingly, p53 is the most studied single gene in history. p53: The Gene that Cracked the Cancer Code tells the story of the discovery of the gene and of medical science's mission to unravel its mysteries and get to the heart of what happens in our cells when they turn cancerous. Through the personal accounts of key researchers, the book reveals the excitement of the hunt for new cures--the hype, the enthusiasm, the lost opportunities, the blind alleys and the thrilling breakthroughs. As the long-anticipated revolution in cancer treatment tailored to each individual patient's symptoms starts to take off at last, p53 is at the cutting edge. This is a timely tale of scientific discovery and advances in our understanding of a disease that still affects more than one in three of us at some point in our lives.

     Nothing could have prepared him for the reality he ended up facing. Placing his focus on the day to day existence of the soldiers in the trenches, Adams presents a grim picture of mud-coated billets, relentless artillery barrages, working parties, training and the art of military sniping. Just as it would have been for the soldiers’ lives, Adams heightens his work with an emotive account of his first night patrol, the detonation of mines, battlefield duels and being wounded whilst out wiring in No Man’s Land. Understated and striving for truth over melodrama, Nothing of Importance is the original memoir of the First World War — the only record published while the conflict was still being fought — and the definitive account of trench warfare. Bernard Adams (1890-1917) was a British Army officer, joining 1 Royal Welsh Fusiliers as a Lieutenant in November 1914. He was the first of a triumvirate of authors who, for a time, served simultaneously in the same battalion: the second was Siegfried Sassoon, the third Robert Graves. Written whilst convalescing in 1916, he did not live to see it published.

    

    After a successful career in the private sector, Nasir El-Rufai rose to the top ranks of Nigeria's political hierarchy, serving first as the privatization czar at the Bureau for Public Enterprises and then as Minister of the Federal Capital Territory of Abuja under former President Olesegun Obasanjo. In this tell-all memoir, El-Rufai reflects on a life in public service to Nigeria, the enormous challenges faced by the country, and what can be done while calling on a new generation of leaders to take the country back from the brink of destruction. The shocking revelations disclosed by El-Rufai about the formation of the current leadership and the actions of prominent statesmen make this memoir required reading for anyone seeking to understand the dynamics of power politics in Africa's most populous nation.

    

    The story of how we got from there to here is full of fascinating people, and in this elegant, entertaining book, Paul Strathern introduces us to ancient philosophers, medieval alchemists, and the earliest chemists-and to Dimitri Mendeleyev, the card-playing nineteenth-century Russian who claimed that the answers came to him in a dream. "Chemistry has been a neglected area of science writing, and Mendeleyev, the king of chemistry, is a largely forgotten genius. [This book] goes a long way toward correcting this injustice." (Simon Singh, author of Fermat's Last Theorem, in the Sunday Telegraph)

    Churchill, 1948: World War II was the defining event of our age—the climactic clash between liberty and tyranny. It led to revolutions, the demise of empires, a protracted Cold War, and religious strife still not ended. Yet Churchill maintained that it was all avoidable. Here is a transformative view of Churchill’s theories, prescriptions, actions, and the degree to which he pursued them in the decade before the war. It shows that he was both right and wrong: right that Hitler could have been stopped; wrong that he did all he could to stop him. It is based on what really happened—evidence that has been “hiding in public” for many years, thoroughly referenced in Churchill’s words and those of his contemporaries. Richard M. Langworth began his Churchill work in 1968 when he organized the Churchill Study Unit, which later became the Churchill Centre. He served as its president and board chairman and was editor of its journal Finest Hour from 1982 to 2014. In November 2014, he was appointed senior fellow for Hillsdale College’s Churchill Project. Mr. Langworth published the first American edition of Churchill’s India, is the author of A Connoisseur’s Guide to the Books of Sir Winston Churchill, and is the editor of Churchill by Himself, The Definitive Wit of Winston Churchill, The Patriot’s Churchill, All Will Be Well: Good Advice from Winston Churchill, and Churchill in His Own Words. His next book is Winston Churchill, Urban Myths and Reality. In 1998, Richard Langworth was appointed a Commander of the Most Excellent Order of the British Empire by HM The Queen “for services to Anglo-American understanding and the memory of Sir Winston Churchill.”

    We were halfway in when the Japanese machine guns got their range. Bullets slapped the water and whined as they ricocheted off the barge. Some of us ducked; some of us fell to the floor; and all of us prayed.” Here, in heart-stopping human detail, are twenty-one personal accounts told by the men themselves. They are the stories of men who lived in hell and lived to tell of it. There is the story of Sgt. Albert Schmid who was awarded the Navy Cross for his single-handed destruction of a flanking attack while on Guadalcanal. The account of Private Nicolli who was literally blown into the air like a matchstick and then, with a piece of shrapnel in his chest, managed to help a wounded comrade to the rear. “The luckiest man in the Solomons,” Sgt. Koziar, tells of how he had his tonsils removed with the assistance of a Japanese sniper’s bullet. These are just three of the twenty-one fascinating stories that were told to Gerold Frank and James Horan just months after these marines had returned from active duty to recover from the conflict in the Pacific. The valor of these marines is astounding, as twenty-one-year-old Corporal Conroy states in the book, “I don’t suppose I shall ever be able to sum up all the bravery, the guts, the genuine, honest courage displayed by the boys out in Guadalcanal. They were afraid, and yet they took it. They had what it takes . . .” The battles of Gavutu-Tanambogo, Tulagi, Tenaru, Matanikau and Guadalcanal are all covered through these accounts which take the reader right to the epicenter of the Pacific conflict. “telling of living conditions on the beaches and in the jungles where they fought, offering an insider’s view of foxholes, food, snipers, mosquitos, boondocks, shrapnel, their injuries, and their pain.” Great Stories of World War II Gerold Frank and James Horan were professional authors who wrote down the stories of these marines shortly after they had returned from active duty. The War in the South Pacific was first published in 1943 as Out in the Boondocks. Frank went on to become a prominent ghostwriter and passed away in 1998. Horan, author of more than forty books, died in 1981.

    Many leadership books can be boring. Instead of reading another repetitive book about 100 leadership essentials by a corporate CEO, search no more for the perfect leadership book. In "The Diary of a West Point Cadet," by Captain Preston Pysh, the author teaches essential West Point leadership through the most fun and unique reading of any book in its class. If you are an aspiring cadet, a small-group leader, or even an emerging leader in corporate America, this book is for you. Each intriguing firsthand account of Preston's most memorable stories from attending West Point will capture your interest and imagination. At the conclusion of each gripping story, Preston efficiently summarizes how the experience taught him lessons about leadership, which later prepared him to be a combat commander. If you like twists and turns while reading and learning, you are in for a treat. Prepare to be glued to your seat and the text as you experience unforgettable stories and lessons from "The Point."

    Every act can be categorized as either a selfish act or a selfless act. “Selfish or Selfless: Which One Are You?,” discusses how you can discover whether or not you are doing things that are selfish (about your own wants, your own need, and your own desires) or whether you are doing things that are selfless (things that are about other people’s wants, other people’s needs and you do things that benefit others). Do you know which one you are? Have you thought about why you do what you do and how it impacts the people around you? Learn how to discover whether you are selfish or selfless and how to change sides if you need to.

     Told in his own inimitable style, Noddy shares insider accounts of his days on the road, along with a healthy dose of celebrity gossip, and leaves no stone unturned as he expounds on some of his favourite subjects – fame, friendship and fatherhood, the perils of social media and the modern age, not to mention what it would be like if he ruled the world . . . From his early days on the West Midlands beat scene, including a stint as a roadie for Robert Plant, Noddy charts his rise from skinhead stomper to international pop-star, statesman, playboy, male model and philosopher, and of course one of the most integral parts of a Great British Christmas. Witty, wise and tremendously funny, this is Noddy Holder at his glittering best.

    But what sort of person was the young Albert Einstein, before he became universally acclaimed as the archetypal genius? And how did his genius unfold? In this brilliant new Kindle Single, scientist Robyn Arianrhod blends biography with popular science to tell the story of how young Albert developed a theory that – unknown to him at first – contained the seeds of his extraordinary equation E = mc2. Arianrhod, who wrote her PhD on Einstein’s general theory of relativity, makes the ideas behind the equation accessible to the lay reader, and sets young Einstein’s exploration of these ideas against the backdrop of his first loves, his family and marriage, and, above all, his childlike wonder at the nature of the universe. She introduces his heroes and scientific inspirations, and the friends who believed in him when no one else did. In personalising Einstein, she brings to life both the man and his science, in a short, easy-to-read narrative. In showing how he discovered his famous equation, and what it means, she draws a compelling portrait of this prodigious intellect whose unfathomable grasp of the building blocks of physics would change our world forever. About the Author: Dr Robyn Arianrhod is the author of two critically acclaimed works of popular science and scientific history: Einstein’s Heroes: Imagining the World Through the Language of Mathematics, and Seduced by Logic: Émilie du Châtelet, Mary Somerville and the Newtonian Revolution. Both were shortlisted for major book awards and are published in the USA. Einstein’s Heroes was translated into several languages. Robyn was awarded her PhD for research on Einstein’s general theory of relativity and has lectured in applied mathematics (including special relativity) for many years. She is currently an Adjunct Research Fellow in the School of Mathematical Sciences at Monash University in Melbourne, where she is undertaking research on the structure of relativistic space-times. She is also a technical reviewer for the American Mathematical Society. Praise for Robyn Arianrhod's books: Einstein’s Heroes ‘Arianrhod’s achievement is to so masterfully combine history, biography, and mathematics as to absorb and enlighten even the mathematically maladroit’ – Booklist ‘An intriguing blend of science, history, and biography . . . Arianrhod’s well-written, fascinating discussion of intertwined topics is highly recommended’ – Library Journal (starred review) ‘A thrilling story . . . Arianrhod brings out the human side of the scientists’ – Bloombergnews ‘Offers readers an engaging intellectual exercise combining physics, language, mathematics, and biography’ – Science News Seduced by Logic ‘Seduced by Logic offers the lay reader an easy and agreeable introduction to the evolution of some crucial scientific debates . . . One cannot help be captivated by her intellectual honesty and enthusiasm’ – Times Higher Education ‘An elegant and inspiring history of how scientific revolutions make their way’ – Edward Dolnick, The Clockwork Universe ‘Here is a skillfully written tapestry of the science, history and portrayal of two of the most charismatic women of mathematical science. Robyn Arianrhod has produced a captivating masterpiece’ – Joseph Mazur, author of Euclid in the Rainforest and What’s Luck Got to Do with It?

    Then, one day she realized that policy was harming her patients, and she took a stand. This resulted in hostility and ostracism by the authorities and her peers in the system.In 2011, depressed and deflated, life was difficult in all directions . . . until she found peace through an unexpected path and a new friend.The co-author of Dissolving Illusions: Disease, Vaccines, and the Forgotten History brings you her entertaining autobiography, which will surprise you and have you wondering if your own doctor could be inadvertently threatening your health.

    

    As a memoir The Jan and Dean Story has elements of humor, tragedy and redemption. It tells their story from the early high school friendship struck up between Jan Berry and Dean Torrence and their ascent to the dizzying heights of stardom riding the crest of the “surf” craze. The Jan and Dean Story is as much about the culture of the 1960s as it is about music. Dean has lived an incredible life and continues to promote a lifestyle and surf culture that is now universally admired and followed throughout the world.The story also recounts Jan’s tragic car accident and his ability to recover enough to continue to perform will be inspiring to many readers even those not familiar with surf music. For pop culture addicts and music buffs alike this book is indispensable. As early teen icons, Jan and Dean left an indelible mark on the music of the 60’s and the American psyche.Dean Torrence is still touring and creating music and often appears with the Beach Boys and other groups from the heyday of surf music.