Book picks similar to
The Great American Drug Deal: A New Prescription for Innovative and Affordable Medicines by Peter Kolchinsky
biotech
non-fiction
economics
healthcare
World Without Mind: The Existential Threat of Big Tech
Franklin Foer - 2017
Over the past few decades there has been a revolution in terms of who controls knowledge and information. This rapid change has imperiled the way we think. Without pausing to consider the cost, the world has rushed to embrace the products and services of four titanic corporations. We shop with Amazon; socialize on Facebook; turn to Apple for entertainment; and rely on Google for information. These firms sell their efficiency and purport to make the world a better place, but what they have done instead is to enable an intoxicating level of daily convenience. As these companies have expanded, marketing themselves as champions of individuality and pluralism, their algorithms have pressed us into conformity and laid waste to privacy. They have produced an unstable and narrow culture of misinformation, and put us on a path to a world without private contemplation, autonomous thought, or solitary introspection--a world without mind. In order to restore our inner lives, we must avoid being coopted by these gigantic companies, and understand the ideas that underpin their success.Elegantly tracing the intellectual history of computer science--from Descartes and the enlightenment to Alan Turing to Stuart Brand and the hippie origins of today's Silicon Valley--Foer exposes the dark underpinnings of our most idealistic dreams for technology. The corporate ambitions of Google, Facebook, Apple, and Amazon, he argues, are trampling longstanding liberal values, especially intellectual property and privacy. This is a nascent stage in the total automation and homogenization of social, political, and intellectual life. By reclaiming our private authority over how we intellectually engage with the world, we have the power to stem the tide.At stake is nothing less than who we are, and what we will become. There have been monopolists in the past but today's corporate giants have far more nefarious aims. They're monopolists who want access to every facet of our identities and influence over every corner of our decision-making. Until now few have grasped the sheer scale of the threat. Foer explains not just the looming existential crisis but the imperative of resistance.
The Scout Mindset: Why Some People See Things Clearly and Others Don't
Julia Galef - 2019
In other words, we have what Julia Galef calls a soldier mindset. From tribalism and wishful thinking, to rationalizing in our personal lives and everything in between, we are driven to defend the ideas we most want to believe--and shoot down those we don't.But if we want to get things right more often, argues Galef, we should train ourselves to have a scout mindset. Unlike the soldier, a scout's goal isn't to defend one side over the other. It's to go out, survey the territory, and come back with as accurate a map as possible. Regardless of what they hope to be the case, above all, the scout wants to know what's actually true.In The Scout Mindset, Galef shows that what makes scouts better at getting things right isn't that they're smarter or more knowledgeable than everyone else. It's a handful of emotional skills, habits, and ways of looking at the world--which anyone can learn. With fascinating examples ranging from how to survive being stranded in the middle of the ocean, to how Jeff Bezos avoids overconfidence, to how superforecasters outperform CIA operatives, to Reddit threads and modern partisan politics, Galef explores why our brains deceive us and what we can do to change the way we think.
It's Even Worse Than You Think: What the Trump Administration is Doing to America
David Cay Johnston - 2018
It's Even Worse Than You Think: What the Trump Administration Is Doing to America tells readers exactly how it is making America worse again.Bestselling author and longtime Trump observer David Cay Johnston shines a light on the political termites who have infested our government under the Trump Administration, destroying it from within and compromising our jobs, safety, finances, and more.No journalist knows Donald Trump better than David Cay Johnston, who has been following him since 1988. It's Even Worse Than You Think: What the Trump Administration Is Doing to America goes inside the administration to show how the federal agencies that touch the lives of all Americans are being undermined. Here is just some of what you will learn:The Wall. Mexican President Enrique Pena Nieto told President Trump that Mexico will never pay for the border wall. So, Trump is proposing putting a tariff on Mexican imports. But a tariff will simply raise the price of Mexican goods in the US, meaning American consumers will end up paying for the wall—if it ever gets built.Climate Change. Welcome to the new EPA, run by Scott Pruitt, a lawyer who has spent much of his career trying to destroy the agency he now heads. Secrecy reigns at the new EPA because Pruitt meets with industry executives to find out which clean air and clean water provisions they most want to roll back, and keeps staffers in the dark to make sure these pro-pollution plans don’t leak prematurely.Stocking the Swamp. Contrary to his promise to “drain the swamp” in Washington, DC, Trump has filled his cabinet with millionaires and billionaires, from Treasury Secretary Steven Mnuchin, a Goldman Sachs and hedge fund veteran who made much of his fortune foreclosing on homeowners to billionaire heiress Education Secretary Betsy DeVos, who has already put the interests of bankers ahead of debt-burdened students and their families.The Kleptocracy. Under Donald Trump conflict of interest is passé. When Trump isn’t in Washington, he stays at one of his properties, where the taxpayers pick up the tab for staffers, Secret Service, and so on, all at full price. And back in Washington, everyone now knows that the Trump International Hotel is the only place to stay if you want to do business with the administration. Meanwhile sons Donald Jr. and Eric run an eyes-wide-open blind trust of Trump holdings to avoid the appearance of conflict of interest—but not the reality.
One Nation Under God: How Corporate America Invented Christian America
Kevin M. Kruse - 2015
But in One Nation Under God, historian Kevin M. Kruse reveals that the belief that America is fundamentally and formally Christian originated in the 1930s.To fight the “slavery” of FDR’s New Deal, businessmen enlisted religious activists in a campaign for “freedom under God” that culminated in the election of their ally Dwight Eisenhower in 1952. The new president revolutionized the role of religion in American politics. He inaugurated new traditions like the National Prayer Breakfast, as Congress added the phrase “under God” to the Pledge of Allegiance and made “In God We Trust” the country’s first official motto. Church membership soon soared to an all-time high of 69 percent. Americans across the religious and political spectrum agreed that their country was “one nation under God.”Provocative and authoritative, One Nation Under God reveals how an unholy alliance of money, religion, and politics created a false origin story that continues to define and divide American politics to this day.
The Upstarts: How Uber, Airbnb, and the Killer Companies of the New Silicon Valley Are Changing the World
Brad Stone - 2017
Uber and Airbnb are household names: redefining neighbourhoods, challenging the way governments regulate business and changing the way we travel.In the spirit of iconic Silicon Valley renegades like Steve Jobs and Bill Gates, a new generation of entrepreneurs is sparking yet another cultural upheaval through technology. They are among the Upstarts, idiosyncratic founders with limitless drive and an abundance of self-confidence. Young, hungry and brilliant, they are rewriting the traditional rules of business, changing our day-to-day lives and often sidestepping serious ethical and legal obstacles in the process.The Upstarts is the definitive account of a dawning age of tenacity, creativity, conflict and wealth. In Brad Stone’s highly anticipated and riveting account of the most radical companies of the new Silicon Valley, we find out how it all started, and how the world is wildly different than it was ten years ago.
Americana: A 400-Year History of American Capitalism
Bhu Srinivasan - 2017
Americana takes us on a four-hundred-year journey of this spirit of innovation and ambition through a series of Next Big Things -- the inventions, techniques, and industries that drove American history forward: from the telegraph, the railroad, guns, radio, and banking to flight, suburbia, and sneakers, culminating with the Internet and mobile technology at the turn of the twenty-first century. The result is a thrilling alternative history of modern America that reframes events, trends, and people we thought we knew through the prism of the value that, for better or for worse, this nation holds dearest: capitalism.In a winning, accessible style, Bhu Srinivasan boldly takes on four centuries of American enterprise, revealing the unexpected connections that link them. We learn how Andrew Carnegie's early job as a telegraph messenger boy paved the way for his leadership of the steel empire that would make him one of the nation's richest men; how the gunmaker Remington reinvented itself in the postwar years to sell typewriters; how the inner workings of the Mafia mirrored the trend of consolidation and regulation in more traditional business; and how a 1950s infrastructure bill triggered a series of events that produced one of America's most enduring brands: KFC. Reliving the heady early days of Silicon Valley, we are reminded that the start-up is an idea as old as America itself.Entertaining, eye-opening, and sweeping in its reach, Americana is an exhilarating new work of narrative history.
This Noble Land
James A. Michener - 1996
Written in Michener's trademark intimate style--so loved by readers in his bestselling memoir The World Is My Home--this book is a must for all Americans in this election year.
The Deficit Myth: Modern Monetary Theory and the Birth of the People's Economy
Stephanie Kelton - 2020
Any ambitious proposal, however, inevitably runs into the buzz saw of how to find the money to pay for it, rooted in myths about deficits that are hobbling us as a country.Kelton busts through the myths that prevent us from taking action: that the federal government should budget like a household, that deficits will harm the next generation, crowd out private investment, and undermine long-term growth, and that entitlements are propelling us toward a grave fiscal crisis.MMT, as Kelton shows, shifts the terrain from narrow budgetary questions to one of broader economic and social benefits. With its important new ways of understanding money, taxes, and the critical role of deficit spending, MMT redefines how to responsibly use our resources so that we can maximize our potential as a society. MMT gives us the power to imagine a new politics and a new economy and move from a narrative of scarcity to one of opportunity.
Life 3.0: Being Human in the Age of Artificial Intelligence
Max Tegmark - 2017
It doesn't shy away from the full range of viewpoints or from the most controversial issues--from superintelligence to meaning, consciousness and the ultimate physical limits on life in the cosmos.
Doing Good Better: How Effective Altruism Can Help You Make a Difference
William MacAskill - 2015
We donate our time and money to charities and causes we deem worthy, choose careers we consider meaningful, and patronize businesses and buy products we believe make the world a better place. Unfortunately, we often base these decisions on assumptions and emotions rather than facts. As a result, even our best intentions often lead to ineffective—and sometimes downright harmful—outcomes. How can we do better? While a researcher at Oxford, trying to figure out which career would allow him to have the greatest impact, William MacAskill confronted this problem head on. He discovered that much of the potential for change was being squandered by lack of information, bad data, and our own prejudice. As an antidote, he and his colleagues developed effective altruism, a practical, data-driven approach that allows each of us to make a tremendous difference regardless of our resources. Effective altruists believe that it’s not enough to simply do good; we must do good better. At the core of this philosophy are five key questions that help guide our altruistic decisions: How many people benefit, and by how much? Is this the most effective thing I can do? Is this area neglected? What would have happened otherwise? What are the chances of success, and how good would success be? By applying these questions to real-life scenarios, MacAskill shows how many of our assumptions about doing good are misguided. For instance, he argues one can potentially save more lives by becoming a plastic surgeon rather than a heart surgeon; measuring overhead costs is an inaccurate gauge of a charity’s effectiveness; and, it generally doesn’t make sense for individuals to donate to disaster relief. MacAskill urges us to think differently, set aside biases, and use evidence and careful reasoning rather than act on impulse. When we do this—when we apply the head and the heart to each of our altruistic endeavors—we find that each of us has the power to do an astonishing amount of good.
From Silk to Silicon: The Story of Globalization Through Ten Extraordinary Lives
Jeffrey E. Garten - 2016
From Silk to Silicon tells the story of who these men and women were, what they did, how they did it and how their achievements continue to shape our world today. They include:• Genghis Khan, who united east and west by conquest and by opening new trade routes built on groundbreaking transportation, communications, and management innovations.• Mayer Amschel Rothschild, who arose from an oppressive Jewish ghetto to establish the most powerful bank the world has seen, and ushered in an era of global finance.• Cyrus Field, who became the father of global communications by leading the effort to build the transatlantic telegraph, the forerunner to global radio, TV, and the worldwide Internet.• Margaret Thatcher, whose controversial policies opened the gusher of substantially free markets that linked economies across borders.• Andy Grove, a Hungarian refugee from the Nazis who built the company—Intel—that figured out how to manufacture complex computer chips on a mass, commercial scale and laid the foundation for Silicon Valley’s computer revolution.Through these stories Jeffrey E. Garten finds the common links between these figure and probes critical questions including: How much influence can any one person have in fundamentally changing the world? And how have past trends in globalization affected the present and how will they shape the future? From Silk to Silicon is an essential book to understanding the past—and the future—of the most powerful force of our times.
Every Patient Tells a Story: Medical Mysteries and the Art of Diagnosis
Lisa Sanders - 2009
Lisa Sanders, author of the monthly New York Times Magazine column "Diagnosis," the inspiration for the hit Fox TV series House, M.D.The experience of being ill can be like waking up in a foreign country. Life, as you formerly knew it, is on hold while you travel through this other world as unknown as it is unexpected. When I see patients in the hospital or in my office who are suddenly, surprisingly ill, what they really want to know is, ‘What is wrong with me?’ They want a road map that will help them manage their new surroundings. The ability to give this unnerving and unfamiliar place a name, to know it–on some level–restores a measure of control, independent of whether or not that diagnosis comes attached to a cure. Because, even today, a diagnosis is frequently all a good doctor has to offer.A healthy young man suddenly loses his memory–making him unable to remember the events of each passing hour. Two patients diagnosed with Lyme disease improve after antibiotic treatment–only to have their symptoms mysteriously return. A young woman lies dying in the ICU–bleeding, jaundiced, incoherent–and none of her doctors know what is killing her. In Every Patient Tells a Story, Dr. Lisa Sanders takes us bedside to witness the process of solving these and other diagnostic dilemmas, providing a firsthand account of the expertise and intuition that lead a doctor to make the right diagnosis.Never in human history have doctors had the knowledge, the tools, and the skills that they have today to diagnose illness and disease. And yet mistakes are made, diagnoses missed, symptoms or tests misunderstood. In this high-tech world of modern medicine, Sanders shows us that knowledge, while essential, is not sufficient to unravel the complexities of illness. She presents an unflinching look inside the detective story that marks nearly every illness–the diagnosis–revealing the combination of uncertainty and intrigue that doctors face when confronting patients who are sick or dying. Through dramatic stories of patients with baffling symptoms, Sanders portrays the absolute necessity and surprising difficulties of getting the patient’s story, the challenges of the physical exam, the pitfalls of doctor-to-doctor communication, the vagaries of tests, and the near calamity of diagnostic errors. In Every Patient Tells a Story, Dr. Sanders chronicles the real-life drama of doctors solving these difficult medical mysteries that not only illustrate the art and science of diagnosis, but often save the patients’ lives.
McMafia: A Journey Through the Global Criminal Underworld
Misha Glenny - 2008
No one would foresee that the greatest success story to arise from these events would be the globalization of organized crime. "McMafia" is a fearless, encompassing, wholly authoritative investigation of the now proven ability of organized crime worldwide to find and service markets driven by a seemingly insatiable demand for illegal wares. Whether discussing the Russian mafia, Colombian drug cartels, or Chinese labor smugglers, Misha Glenny makes clear how organized crime feeds off the poverty of the developing world, how it exploits new technology in the forms of cybercrime and identity theft, and how both global crime and terror are fueled by an identical source: the triumphant material affluence of the West. To trace the disparate strands of this hydra-like story, Glenny talked to police, victims, politicians, and members of the global underworld in eastern Europe, North and South America, Africa, the Middle East, China, Japan, and India. The story of organized crime's phenomenal, often shocking growth is truly the central political story of our time. "McMafia "will change the way we look at the world.
The Inevitable: Understanding the 12 Technological Forces That Will Shape Our Future
Kevin Kelly - 2016
In this fascinating, provocative new book, Kevin Kelly provides an optimistic road map for the future, showing how the coming changes in our lives—from virtual reality in the home to an on-demand economy to artificial intelligence embedded in everything we manufacture—can be understood as the result of a few long-term, accelerating forces. Kelly both describes these deep trends—flowing, screening, accessing, sharing, filtering, remixing, tracking, and questioning—and demonstrates how they overlap and are codependent on one another. These larger forces will completely revolutionize the way we buy, work, learn, and communicate with each other. By understanding and embracing them, says Kelly, it will be easier for us to remain on top of the coming wave of changes and to arrange our day-to-day relationships with technology in ways that bring forth maximum benefits. Kelly’s bright, hopeful book will be indispensable to anyone who seeks guidance on where their business, industry, or life is heading—what to invent, where to work, in what to invest, how to better reach customers, and what to begin to put into place—as this new world emerges.
Trust Me, I'm Lying: Confessions of a Media Manipulator
Ryan Holiday - 2012
A malicious online rumor costs a company millions. A political sideshow derails the national news cycle and destroys a candidate. Some product or celebrity zooms from total obscurity to viral sensation. What you don't know is that someone is responsible for all this. Usually, someone like me.I'm a media manipulator. In a world where blogs control and distort the news, my job is to control blogs--as much as any one person can. In today's culture... 1) Blogs like "Gawker," "Buzzfeed" and the "Huffington Post" drive the media agenda. 2) Bloggers are slaves to money, technology, and deadlines. 3) Manipulators wield these levers to shape everything you read, see and watch--online and off.Why am I giving away these secrets? Because I'm tired of a world where blogs take indirect bribes, marketers help write the news, reckless journalists spread lies, and no one is accountable for any of it. I'm pulling back the curtain because I don't want anyone else to get blindsided. I'm going to explain exactly how the media "really" works. What you choose to do with this information is up to you.