Tome was born in 1782 near present-day Harrisburg and lived on the upper Susquehanna for much of his life. He tells colorful (and mostly true) tales about his hunting exploits in the Pennsylvania wilderness, as he tracked elk, wolves, bears, panthers, foxes, and other large animals through the state’s north-central mountains, earning wide renown among his contemporaries. His stories contain suspenseful chase scenes, accidents, and narrow escapes, inviting the reader to view a still-wild Pennsylvania through the eyes of one who “was never conquered by man or animal.” Pioneer Life, originally published in 1854, has since been reprinted several times. This classic hunting memoir includes the following chapters: I. Birth and Early Life II. Hunting the Elk III. Capturing a Live Elk IV. Face of the Country V. Face of the Country — Continued VI. Danger From Rattlesnakes VII. Wolf and Bear Hunting VIII. Another Elk Hunt IX. Elk-Hunting on the Susquehannah X. Elk-Hunting — Continued XI. Nature, Habits, and Manner of Hunting the Elk XII. Elk and Bear Hunting in Winter XIII. Hunting on the Clarion River XIV. Hunting and Trapping XV. The Bear, Its Nature and Habits XVI. Hunting Deer at Different Seasons XVII. Nature and Habits of the Panther, Wolf and Fox XVIII. Rattlesnakes and Their Habits XIX. Distinguished Lumbermen, Etc. XX.. Reminiscences of Cornplanter XXI. Indian Eloquence This book originally published in 1854 has been reformatted for the Kindle and may contain an occasional defect from the original publication or from the reformatting

    In The Poisoner's Handbook Blum draws from highly original research to track the fascinating, perilous days when a pair of forensic scientists began their trailblazing chemical detective work, fighting to end an era when untraceable poisons offered an easy path to the perfect crime. Drama unfolds case by case as the heroes of The Poisoner's Handbook—chief medical examiner Charles Norris and toxicologist Alexander Gettler—investigate a family mysteriously stricken bald, Barnum and Bailey's Famous Blue Man, factory workers with crumbling bones, a diner serving poisoned pies, and many others. Each case presents a deadly new puzzle and Norris and Gettler work with a creativity that rivals that of the most imaginative murderer, creating revolutionary experiments to tease out even the wiliest compounds from human tissue. Yet in the tricky game of toxins, even science can't always be trusted, as proven when one of Gettler's experiments erroneously sets free a suburban housewife later nicknamed "America's Lucretia Borgia" to continue her nefarious work. From the vantage of Norris and Gettler's laboratory in the infamous Bellevue Hospital it becomes clear that killers aren't the only toxic threat to New Yorkers. Modern life has created a kind of poison playground, and danger lurks around every corner. Automobiles choke the city streets with carbon monoxide; potent compounds, such as morphine, can be found on store shelves in products ranging from pesticides to cosmetics. Prohibition incites a chemist's war between bootleggers and government chemists while in Gotham's crowded speakeasies each round of cocktails becomes a game of Russian roulette. Norris and Gettler triumph over seemingly unbeatable odds to become the pioneers of forensic chemistry and the gatekeepers of justice during a remarkably deadly time. A beguiling concoction that is equal parts true crime, twentieth-century history, and science thriller, The Poisoner's Handbook is a page-turning account of a forgotten New York.

    The most fatal virus known to science, rabies — a disease that spreads avidly from animals to humans — kills nearly one hundred percent of its victims once the infection takes root in the brain. In this critically acclaimed exploration, journalist Bill Wasik and veterinarian Monica Murphy chart four thousand years of the history, science, and cultural mythology of rabies. From Greek myths to zombie flicks, from the laboratory heroics of Louis Pasteur to the contemporary search for a lifesaving treatment, Rabid is a fresh and often wildly entertaining look at one of humankind’s oldest and most fearsome foes.

    He wrote vast volumes about animals. He described them, classified them, told us where and how they live and how they develop in the womb or in the egg. He founded a science. It can even be said that he founded science itself.In The Lagoon, acclaimed biologist Armand Marie Leroi recovers Aristotle’s science. He revisits Aristotle’s writings and the places where he worked. He goes to the eastern Aegean island of Lesbos to see the creatures that Aristotle saw, where he saw them. He explores Aristotle’s observations, his deep ideas, his inspired guesses—and the things he got wildly wrong. He shows how Aristotle’s science is deeply intertwined with his philosophical system and reveals that he was not only the first biologist, but also one of the greatest.The Lagoon is both a travelogue and a study of the origins of science. And it shows how a philosopher who lived almost two millennia ago still has so much to teach us today.

    Beginning with a dramatic account of the SARS pandemic at the start of the 21st century, Dorothy Crawford takes us back in time to follow the interlinked history of microbes and humanity, offering an up-to-date look at ancient plagues and epidemics, and identifying key changes in the way humans have lived--such as our move from hunter-gatherer to farmer to city-dweller--which made us ever more vulnerable to microbe attack. Showing that how we live our lives today--with increased crowding and air travel--puts us once again at risk, Crawford asks whether we might ever conquer microbes completely. Among the possible answers, one thing becomes clear: that for generations to come, our deadly companions will continue to influence our lives. New in Paperback

    Drawing on newly available papers of Jonas Salk, Albert Sabin and other key players, Oshinsky paints a suspenseful portrait of the race for the cure, weaving a dramatic tale centered on the furious rivalry between Salk and Sabin. He also tells the story of Isabel Morgan, perhaps the most talented of all polio researchers, who might have beaten Salk to the prize if she had not retired to raise a family.Oshinsky offers an insightful look at the National Foundation for Infantile Paralysis, which was founded in the 1930s by FDR and Basil O'Connor, it revolutionized fundraising and the perception of disease in America. Oshinsky also shows how the polio experience revolutionized the way in which the government licensed and tested new drugs before allowing them on the market, and the way in which the legal system dealt with manufacturers' liability for unsafe products. Finally, and perhaps most tellingly, Oshinsky reveals that polio was never the raging epidemic portrayed by the media, but in truth a relatively uncommon disease. But in baby-booming America--increasingly suburban, family-oriented, and hygiene-obsessed--the specter of polio, like the specter of the atomic bomb, soon became a cloud of terror over daily life.Both a gripping scientific suspense story and a provocative social and cultural history, Polio opens a fresh window onto postwar America.

    It killed more people in twenty-four months than AIDS killed in twenty-four years, more in a year than the Black Death killed in a century. But this was not the Middle Ages, and 1918 marked the first collision of science and epidemic disease. Magisterial in its breadth of perspective and depth of research and now revised to reflect the growing danger of the avian flu, The Great Influenza is ultimately a tale of triumph amid tragedy, which provides us with a precise and sobering model as we confront the epidemics looming on our own horizon. John M. Barry has written a new afterword for this edition that brings us up to speed on the terrible threat of the avian flu and suggest ways in which we might head off another flu pandemic.

     When her wagon train was 8 miles from Fort Laramie, Wyoming, a Sioux Oglalas war party, in war-paint, suddenly appeared and began to encircle their wagons, pretending to be most friendly and asking for presents. The Indians urged the emigrants on, and offered to accompany them, so that they pushed on in company for a short time, until it was saw that they were approaching a ravine where his party would be at a disadvantage, and he insisted on camping outside of it. The Indians, after some hesitation, agreed, and the travellers began to make preparations for supper, when suddenly the Indians fired a volley at them. Some of those who escaped the attack succeeded in hiding in the brushwood, but Mrs. Kelly and her adopted daughter, Mary, as well as Mrs. Larimer and her children, became the prisoners of the Indians. After the second night of capture, Larimer and her son Frank managed to escape and were later reunited with her husband at Camp Collins, Colorado Territory. Larimer wrote of her harrowing captivity and escape in her 1871 book "The Capture and Escape: Life Among the Sioux." In describing dangers encountered during their escape from the Indians, Larimer noted: "The horrors of our situation were harassing to contemplate. The wolves seemed congregated upon the highlands, and, awaking from their night’s repose, their wailing cries echoed back from the distant hills with terrific clearness. These prowling creatures abound in that country, where some species attain a great size. Even the buffalo, which does not fear them in the herd, knows his danger when overtaken alone; and the solitary bull, secreted from its hunter, succumbs before the united force of a gang of wolves." Sarah Luse Larimer (1836-1913) was born in Pennsylvania, headed west in 1859 with her husband, living for a while in Allen County, Kansas, where she operated a photographic gallery. In 1864, along with her husband and son the family set out for the mines of Idaho Territory, when their plans were disrupted by Oglalas on the warpath. John Bratt in his 1921 book "Trails of Yesterday" writes of Larimer: "At Sherman Station I became well acquainted with Mrs. Larimer and her son, who kept a general store there, bought and sold ties and cord wood, while her husband had a star route mail contract from Point of Rocks north. There was also a Mrs. Kelly living near the station. These two women and Mrs. Larimer's son had been captured by the Sioux Indians near Fort Laramie. Mrs. Larimer and her son, after two weeks' captivity in the lodge of the chief, stole away one night and though the Indians hunted them day and night, they succeeded in eluding them and got back to the fort, after suffering unmentionable cruelties. Mrs. Kelly, not so fortunate, was taken by the Indians up on the Missouri River and kept with the band over six months." In describing the moment of rescue by a passing wagon train, Larimer writes that "as we sat in this shelter, which proved to be the last, a most joyful and welcome sound greeted our ears —one in which there was no mistake—our own language, spoken by some boys who passed, driving cattle."

    Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee’s own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive—and to increase our understanding of this iconic disease. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

    His “Uncle” Ed Pucci, who was Frank Sinatra’s bodyguard and a close family friend, set him up with an entry level dealer’s job in Vegas. Over the next three decades, Jimmy experienced all Las Vegas had to offer. He dealt craps to famous gangsters in a private game, he interacted with John Wayne, Elvis Presley, Redd Foxx, Debbie Reynolds, Louis Prima and other celebrities. Jimmy was a confirmed bachelor who lived the high life with the ladies, although at times his carousing nearly cost him his life. He saw hundreds of thousands of dollars bet on one roll of the dice, he caught gambling cheaters and had run ins with some very nasty types. ˃˃˃ Folktales from a bygone era Jimmy’s stories are folktales from a bygone era, the 1960s, 70s and 80s when Vegas was still a relatively small town. Back in the day, the “joints” were ruled by men whose names all ended in vowels and there was a good time to be had 24/7. When It Was Great will make you laugh and touch your heart, but most of all it will take you back to the Las Vegas of yesterday, when the Rat Pack played at the Sands, Elvis headlined at the Hilton and working stiffs like Jimmy partied like there was no tomorrow. Scroll up and grab a copy today.

    He was a celebrity during the height of America’s Gilded Age. In this book, you will read about his friendship with Mark Twain, his furious competition with his former employer Thomas Edison, his uneasy relationship with billionaire J.P. Morgan, and his rivalry with Albert Einstein. During his lifetime, Tesla revolutionized the field of electrical engineering with his most famous invention: the induction motor. But that wasn’t all he contributed to the world of technology. His coils, turbines, robotic boats, and mysterious “death ray” continue to beguile the imagination and inspire the inventors of the 21st century. But who was Tesla really? This book will take you from his early childhood in Croatia, where he experienced strange optical visions and “luminous phenomenon” that gave him near super-human powers of memory and visualization, to the “War of the Currents”, Thomas Edison’s bizarre campaign to ruin Tesla’s reputation. From trying to fight the Spanish American War with robots, to electrifying the skies of the Colorado desert, and to starting an earthquake in the middle of New York city, learn how Nikola Tesla shaped the world we live in today.

    In this sensational and macabre story, we meet the surgeon who counted not only luminaries Benjamin Franklin, Lord Byron, Adam Smith, and Thomas Gainsborough among his patients but also “resurrection men” among his close acquaintances. A captivating portrait of his ruthless devotion to uncovering the secrets of the human body, and the extraordinary lengths to which he went to do so—including body snatching, performing pioneering medical experiments, and infecting himself with venereal disease—this rich historical narrative at last acknowledges this fascinating man and the debt we owe him today.

    These “psychosurgeons,” as they called themselves, occupied a gray zone between medical research and medical practice, and ended up subjecting untold numbers of people to the types of surgical experiments once limited to chimpanzees.The most important test subject to emerge from this largely untold chapter in American history was a twenty-seven-year-old factory worker named Henry Molaison. In 1953, Henry—who suffered from severe epilepsy—received a radical new version of the lobotomy, one that targeted the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry left the operating room profoundly amnesic, unable to create new long-term memories. Over the next sixty years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.Luke Dittrich uses the case of Patient H.M. as a starting point for a kaleidoscopic journey, one that moves from the first recorded brain surgeries in ancient Egypt to the cutting-edge laboratories of MIT. He takes readers inside the old asylums and operating theaters where psychosurgeons conducted their human experiments, and behind the scenes of a bitter custody battle over the ownership of the most important brain in the world. Throughout, Dittrich delves into the enduring mysteries of the mind while exposing troubling stories of just how far we’ve gone in our pursuit of knowledge. It is also, at times, a deeply personal journey. Dittrich’s grandfather was the brilliant, morally complex surgeon who operated on Molaison—and thousands of other patients. The author’s investigation into the dark roots of modern memory science ultimately forces him to confront unsettling secrets in his own family history, and to reveal the tragedy that fueled his grandfather’s relentless experimentation—experimentation that would revolutionize our understanding of ourselves.Patient H.M. combines the best of biography, memoir, and science journalism to create a haunting, endlessly fascinating story, one that reveals the wondrous and devastating things that can happen when hubris, ambition, and human imperfection collide.

    She conjures up early operating theaters--no place for the squeamish--and surgeons, working before anesthesia, who were lauded for their speed and brute strength. These medical pioneers knew that the aftermath of surgery was often more dangerous than their patients' afflictions, and they were baffled by the persistent infections that kept mortality rates stubbornly high. At a time when surgery couldn't have been more hazardous, an unlikely figure stepped forward: a young, melancholy Quaker surgeon named Joseph Lister, who would solve the deadly riddle and change the course of history.Fitzharris dramatically recounts Lister's discoveries in gripping detail, culminating in his audacious claim that germs were the source of all infection--and could be countered by antiseptics. Focusing on the tumultuous period from 1850 to 1875, she introduces us to Lister and his contemporaries--some of them brilliant, some outright criminal--and takes us through the grimy medical schools and dreary hospitals where they learned their art, the deadhouses where they studied anatomy, and the graveyards they occasionally ransacked for cadavers.Eerie and illuminating, The Butchering Art celebrates the triumph of a visionary surgeon whose quest to unite science and medicine delivered us into the modern world.

    The Lady and Her Monsters by Roseanne Motillo brings to life the fascinating times, startling science, and real-life horrors behind Mary Shelley’s gothic masterpiece, Frankenstein.Montillo recounts how—at the intersection of the Romantic Age and the Industrial Revolution—Shelley’s Victor Frankenstein was inspired by actual scientists of the period: curious and daring iconoclasts who were obsessed with the inner workings of the human body and how it might be reanimated after death.With true-life tales of grave robbers, ghoulish experiments, and the ultimate in macabre research—human reanimation—The Lady and Her Monsters is a brilliant exploration of the creation of Frankenstein, Mary Shelley’s horror classic.