Dr. Oliver Sacks recounts the stories of patients struggling to adapt to often bizarre worlds of neurological disorder. Here are people who can no longer recognize everyday objects or those they love; who are stricken with violent tics or shout involuntary obscenities; who have been dismissed as autistic or retarded, yet are gifted with uncanny artistic or mathematical talents. If inconceivably strange, these brilliant tales illuminate what it means to be human.

    Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee’s own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive—and to increase our understanding of this iconic disease. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

    Exploring the history of cannibalism, the neurology of people who are sexually attracted to animals, the evolution of human body fluids, the science of homosexuality, and serious questions about life and death, Bering astutely covers a generous expanse of our kaleidoscope of quirks and origins.With his characteristic irreverence and trademark cheekiness, Bering leaves no topic unturned or curiosity unexamined, and he does it all with an audaciously original voice. Whether you're interested in the psychological history behind the many facets of sexual desire or the evolutionary patterns that have dictated our current mystique and phallic physique, Why Is the Penis Shaped Like That? is bound to create lively discussion and debate for years to come.

    Humans have feared them for centuries, long considering them the assassins and pariahs of the natural world.Now, in Venomous, the biologist Christie Wilcox investigates and illuminates the animals of our nightmares, arguing that they hold the keys to a deeper understanding of evolution, adaptation, and immunity. She reveals just how venoms function and what they do to the human body. With Wilcox as our guide, we encounter a jellyfish with tentacles covered in stinging cells that can kill humans in minutes; a two-inch caterpillar with toxic bristles that trigger hemorrhaging; and a stunning blue-ringed octopus capable of inducing total paralysis. How do these animals go about their deadly work? How did they develop such intricate, potent toxins? Wilcox takes us around the world and down to the cellular level to find out.Throughout her journey, Wilcox meets the intrepid scientists who risk their lives studying these lethal beasts, as well as “self-immunizers” who deliberately expose themselves to snakebites. Along the way, she puts her own life on the line, narrowly avoiding being envenomated herself. Drawing on her own research, Wilcox explains how venom scientists are untangling the mechanisms of some of our most devastating diseases, and reports on pharmacologists who are already exploiting venoms to produce lifesaving drugs. We discover that venomous creatures are in fact keystone species that play crucial roles in their ecosystems and ours—and for this alone, they ought to be protected and appreciated.Thrilling and surprising at every turn, Venomous will change everything you thought you knew about the planet’s most dangerous animals.

    By examining fossils and DNA, Shubin shows us that our hands actually resemble fish fins, our head is organized like that of a long-extinct jawless fish, and major parts of our genome look and function like those of worms and bacteria.Shubin makes us see ourselves and our world in a completely new light. Your Inner Fish is science writing at its finest-enlightening, accessible, and told with irresistible enthusiasm.

    In luminous, razor-sharp prose, Nordhaus explores the vital role that honeybees play in American agribusiness, the maintenance of our food chain, and the very future of the nation. With an intimate focus and incisive reporting, in a book perfect for fans of Eric Schlosser’s Fast Food Nation, Michael Pollan’s The Botany of Desire,and John McPhee’s Oranges, Nordhaus’s stunning exposé illuminates one the most critical issues facing the world today,offering insight, information, and, ultimately, hope.

    These “psychosurgeons,” as they called themselves, occupied a gray zone between medical research and medical practice, and ended up subjecting untold numbers of people to the types of surgical experiments once limited to chimpanzees.The most important test subject to emerge from this largely untold chapter in American history was a twenty-seven-year-old factory worker named Henry Molaison. In 1953, Henry—who suffered from severe epilepsy—received a radical new version of the lobotomy, one that targeted the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry left the operating room profoundly amnesic, unable to create new long-term memories. Over the next sixty years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.Luke Dittrich uses the case of Patient H.M. as a starting point for a kaleidoscopic journey, one that moves from the first recorded brain surgeries in ancient Egypt to the cutting-edge laboratories of MIT. He takes readers inside the old asylums and operating theaters where psychosurgeons conducted their human experiments, and behind the scenes of a bitter custody battle over the ownership of the most important brain in the world. Throughout, Dittrich delves into the enduring mysteries of the mind while exposing troubling stories of just how far we’ve gone in our pursuit of knowledge. It is also, at times, a deeply personal journey. Dittrich’s grandfather was the brilliant, morally complex surgeon who operated on Molaison—and thousands of other patients. The author’s investigation into the dark roots of modern memory science ultimately forces him to confront unsettling secrets in his own family history, and to reveal the tragedy that fueled his grandfather’s relentless experimentation—experimentation that would revolutionize our understanding of ourselves.Patient H.M. combines the best of biography, memoir, and science journalism to create a haunting, endlessly fascinating story, one that reveals the wondrous and devastating things that can happen when hubris, ambition, and human imperfection collide.

    Have you ever wondered if your dog might be a bit depressed? How about heartbroken or homesick? Animal Madness takes these questions seriously, exploring the topic of mental health and recovery in the animal kingdom and turning up lessons that Publishers Weekly calls “Illuminating…Braitman’s delightful balance of humor and poignancy brings each case of life….[Animal Madness’s] continuous dose of hope should prove medicinal for humans and animals alike.” Susan Orlean calls Animal Madness “a marvelous, smart, eloquent book—as much about human emotion as it is about animals and their inner lives.” It is “a gem…that can teach us much about the wildness of our own minds” (Psychology Today).

    Complications lays bare a science not in its idealized form but as it actually is--uncertain, perplexing, and profoundly human.Complications is a 2002 National Book Award Finalist for Nonfiction.

    Recent, massive blooms of billions of jellyfish have clogged power plants, decimated fisheries, and caused millions of dollars of damage. Driven by questions about how overfishing, coastal development, and climate change were contributing to a jellyfish population explosion, Juli embarked on a scientific odyssey. She traveled the globe to meet the biologists who devote their careers to jellies, hitched rides on Japanese fishing boats to see giant jellyfish in the wild, raised jellyfish in her dining room, and throughout it all marveled at the complexity of these alluring and ominous biological wonders.

    We ignore this reality most of the time, but when a new threat (Ebola, SARS, Zika) seems imminent, we send our best and bravest doctors to contain it--people like Dr. Ali S. Khan.In his long career as a public health first responder—protected by a thin mask from infected patients, napping under nets to keep out scorpions, making life-and-death decisions on limited, suspect information—Khan has found that rogue microbes will always be a problem, but outbreaks are often caused by people. We make mistakes, politicize emergencies, and, too often, fail to imagine the consequences of our actions.The Next Pandemic is a firsthand account of disasters like anthrax, bird flu, and others and how we could do more to prevent their return. It's both a gripping story of our brushes with fate and an urgent lesson on how we can keep ourselves safe from the inevitable next pandemic.

    But in the modern world, the breast is changing. Breasts are getting bigger, arriving earlier, and attracting newfangled chemicals. Increasingly, the odds are stacked against us in the struggle with breast cancer, even among men. What makes breasts so mercurial—and so vulnerable?In this informative and highly entertaining account, intrepid science reporter Florence Williams sets out to uncover the latest scientific findings from the fields of anthropology, biology, and medicine. Her investigation follows the life cycle of the breast from puberty to pregnancy to menopause, taking her from a plastic surgeon’s office where she learns about the importance of cup size in Texas to the laboratory where she discovers the presence of environmental toxins in her own breast milk. The result is a fascinating exploration of where breasts came from, where they have ended up, and what we can do to save them.

    These are today's sins of science—as deplorable as mistaken past ideas about advocating racial purity or using lobotomies as a cure for mental illness. These unwitting errors add up to seven lessons both cautionary and profound, narrated by renowned author and speaker Paul A. Offit. Offit uses these lessons to investigate how we can separate good science from bad, using some of today's most controversial creations—e-cigarettes, GMOs, drug treatments for ADHD—as case studies. For every "Aha!" moment that should have been an "Oh no," this book is an engrossing account of how science has been misused disastrously—and how we can learn to use its power for good.

    But, despite appearances, these are not dogs—they are foxes. They are the result of the most astonishing experiment in breeding ever undertaken—imagine speeding up thousands of years of evolution into a few decades. In 1959, biologists Dmitri Belyaev and Lyudmila Trut set out to do just that, by starting with a few dozen silver foxes from fox farms in the USSR and attempting to recreate the evolution of wolves into dogs in real time in order to witness the process of domestication. This is the extraordinary, untold story of this remarkable undertaking. Most accounts of the natural evolution of wolves place it over a span of about 15,000 years, but within a decade, Belyaev and Trut’s fox breeding experiments had resulted in puppy-like foxes with floppy ears, piebald spots, and curly tails. Along with these physical changes came genetic and behavioral changes, as well. The foxes were bred using selection criteria for tameness, and with each generation, they became increasingly interested in human companionship. Trut has been there the whole time, and has been the lead scientist on this work since Belyaev’s death in 1985, and with Lee Dugatkin, biologist and science writer, she tells the story of the adventure, science, politics, and love behind it all.  In How to Tame a Fox, Dugatkin and Trut take us inside this path-breaking experiment in the midst of the brutal winters of Siberia to reveal how scientific history is made and continues to be made today. To date, fifty-six generations of foxes have been domesticated, and we continue to learn significant lessons from them about the genetic and behavioral evolution of domesticated animals. How to Tame a Fox offers an incredible tale of scientists at work, while also celebrating the deep attachments that have brought humans and animals together throughout time.

    In The Viral Storm, award-winning biologist Nathan Wolfe tells the story of how viruses and human beings have evolved side by side through history; how deadly viruses like HIV, swine flu, and bird flu almost wiped us out in the past; and why modern life has made our species vulnerable to the threat of a global pandemic.Wolfe's research missions to the jungles of Africa and the rain forests of Borneo have earned him the nickname "the Indiana Jones of virus hunters," and here Wolfe takes readers along on his groundbreaking and often dangerous research trips—to reveal the surprising origins of the most deadly diseases and to explain the role that viruses have played in human evolution.In a world where each new outbreak seems worse than the one before, Wolfe points the way forward, as new technologies are brought to bear in the most remote areas of the world to neutralize these viruses and even harness their power for the good of humanity. His provocative vision of the future will change the way we think about viruses, and perhaps remove a potential threat to humanity's survival.