This was the world of medicine when Thomas Dent Mütter began his trailblazing career as a plastic surgeon in Philadelphia during the middle of the nineteenth century.Although he died at just forty-eight, Mütter was an audacious medical innovator who pioneered the use of ether as anesthesia, the sterilization of surgical tools, and a compassion-based vision for helping the severely deformed, which clashed spectacularly with the sentiments of his time.   Brilliant, outspoken, and brazenly handsome, Mütter was flamboyant in every aspect of his life. He wore pink silk suits to perform surgery, added an umlaut to his last name just because he could, and amassed an immense collection of medical oddities that would later form the basis of Philadelphia’s Mütter Museum. Cristin O’Keefe Aptowicz chronicles how Mütter’s efforts helped establish Philadelphia as a global mecca for medical innovation—despite intense resistance from his numerous rivals.

    While some books explore our genetic inheritance and popular television shows celebrate ancestry, this is the first book to explore how everything from DNA to emotions to names and the stories that form our lives are all part of our human legacy. This book shows how trust is inherited in Africa, silence is passed down in Tasmania, and how the history of nations is written in our DNA. From fateful, ancient encounters to modern mass migrations and medical diagnoses, Kenneally explains how the forces that shaped the history of the world ultimately shape each human who inhabits it. The Invisible History of the Human Race is a deeply researched, carefully crafted, and provocative perspective on how our stories, psychology, and genetics affect our past and our future.

    Dr. Manheimer describes the plights of twelve very different patients--from dignitaries at the nearby UN, to supermax prisoners at Riker's Island, to illegal immigrants, and Wall Street tycoons.Manheimer was not only the medical director of the country's oldest public hospital for over 13 years, but he was also a patient. As the book unfolds, the narrator is diagnosed with cancer, and he is forced to wrestle with the end of his own life even as he struggles to save the lives of others.

    It intersects with Darwin’s theory of evolution, and collides with the horrors of Nazi eugenics in the 1940s. The gene transforms post-war biology. It reorganizes our understanding of sexuality, temperament, choice and free will. This is a story driven by human ingenuity and obsessive minds – from Charles Darwin and Gregor Mendel to Francis Crick, James Watson and Rosalind Franklin, and the thousands of scientists still working to understand the code of codes.This is an epic, moving history of a scientific idea coming to life, by the author of The Emperor of All Maladies. But woven through The Gene, like a red line, is also an intimate history – the story of Mukherjee’s own family and its recurring pattern of mental illness, reminding us that genetics is vitally relevant to everyday lives. These concerns reverberate even more urgently today as we learn to “read” and “write” the human genome – unleashing the potential to change the fates and identities of our children.Majestic in its ambition, and unflinching in its honesty, The Gene gives us a definitive account of the fundamental unit of heredity – and a vision of both humanity’s past and future.

    The author argues for the preservation of the time and space in which to walk in an ever more car-dependent and accelerated world.

    David Starr Jordan was a taxonomist, a man possessed with bringing order to the natural world. In time, he would be credited with discovering nearly a fifth of the fish known to humans in his day. But the more of the hidden blueprint of life he uncovered, the harder the universe seemed to try to thwart him. His specimen collections were demolished by lightning, by fire, and eventually by the 1906 San Francisco earthquake—which sent more than a thousand of his discoveries, housed in fragile glass jars, plummeting to the floor. In an instant, his life’s work was shattered. Many might have given up, given in to despair. But Jordan? He surveyed the wreckage at his feet, found the first fish he recognized, and confidently began to rebuild his collection. And this time, he introduced one clever innovation that he believed would at last protect his work against the chaos of the world. When NPR reporter Lulu Miller first heard this anecdote in passing, she took Jordan for a fool—a cautionary tale in hubris, or denial. But as her own life slowly unraveled, she began to wonder about him. Perhaps instead he was a model for how to go on when all seemed lost. What she would unearth about his life would transform her understanding of history, morality, and the world beneath her feet. Part biography, part memoir, part scientific adventure, Why Fish Don’t Exist reads like a fable about how to persevere in a world where chaos will always prevail.

    It means more than the arrival of trendy shops, much-maligned hipsters, and expensive lattes. The very future of American cities as vibrant, equitable spaces hangs in the balance.Peter Moskowitz's How to Kill a City takes readers from the kitchen tables of hurting families who can no longer afford their homes to the corporate boardrooms and political backrooms where destructive housing policies are devised. Along the way, Moskowitz uncovers the massive, systemic forces behind gentrification in New Orleans, Detroit, San Francisco, and New York. The deceptively simple question of who can and cannot afford to pay the rent goes to the heart of America's crises of race and inequality. In the fight for economic opportunity and racial justice, nothing could be more important than housing.A vigorous, hard-hitting expose, How to Kill a City reveals who holds power in our cities-and how we can get it back

    Why does music evoke such powerful moods? The answers are at last be- coming clear, thanks to revolutionary neuroscience and the emerging field of evolutionary psychology. Both a cutting-edge study and a tribute to the beauty of music itself, This Is Your Brain on Music unravels a host of mysteries that affect everything from pop culture to our understanding of human nature, including: • Are our musical preferences shaped in utero? • Is there a cutoff point for acquiring new tastes in music? • What do PET scans and MRIs reveal about the brain’s response to music? • Is musical pleasure different from other kinds of pleasure?This Is Your Brain on Music explores cultures in which singing is considered an essential human function, patients who have a rare disorder that prevents them from making sense of music, and scientists studying why two people may not have the same definition of pitch. At every turn, this provocative work unlocks deep secrets about how nature and nurture forge a uniquely human obsession.

    But the glory of each essay lies in Childs's ability to portray the sometimes brutal beauty of the wilderness, to capture the individual essence of wild creatures, to transport the reader beyond the human realm and deep inside the animal kingdom.

    The tiger isn’t just killing people, it’s annihilating them, and a team of men and their dogs must hunt it on foot through the forest in the brutal cold. As the trackers sift through the gruesome remains of the victims, they discover that these attacks aren’t random: the tiger is apparently engaged in a vendetta. Injured, starving, and extremely dangerous, the tiger must be found before it strikes again.As he re-creates these extraordinary events, John Vaillant gives us an unforgettable portrait of this spectacularly beautiful and mysterious region. We meet the native tribes who for centuries have worshipped and lived alongside tigers, even sharing their kills with them. We witness the arrival of Russian settlers in the nineteenth and early twentieth centuries, soldiers and hunters who greatly diminished the tiger populations. And we come to know their descendants, who, crushed by poverty, have turned to poaching and further upset the natural balance of the region.This ancient, tenuous relationship between man and predator is at the very heart of this remarkable book. Throughout we encounter surprising theories of how humans and tigers may have evolved to coexist, how we may have developed as scavengers rather than hunters, and how early Homo sapiens may have fit seamlessly into the tiger’s ecosystem. Above all, we come to understand the endangered Siberian tiger, a highly intelligent super-predator that can grow to ten feet long, weigh more than six hundred pounds, and range daily over vast territories of forest and mountain.Beautifully written and deeply informative, The Tiger circles around three main characters: Vladimir Markov, a poacher killed by the tiger; Yuri Trush, the lead tracker; and the tiger himself. It is an absolutely gripping tale of man and nature that leads inexorably to a final showdown in a clearing deep in the taiga.

    Some of their responses to those outbreaks are almost too strange to believe in hindsight. Get Well Soon delivers the gruesome, morbid details of some of the worst plagues we’ve suffered as a species, as well as stories of the heroic figures who selflessly fought to ease the suffering of their fellow man. With her signature mix of in-depth research and storytelling, and not a little dark humor, Jennifer Wright explores history’s most gripping and deadly outbreaks, and ultimately looks at the surprising ways they’ve shaped history and humanity for almost as long as anyone can remember.

    There are Douglas firs as tall as skyscrapers, and a banyan tree in Calcutta as big as a football field.From the tallest to the smallest, trees inspire wonder in all of us, and in The Tree, Colin Tudge travels around the world—throughout the United States, the Costa Rican rain forest, Panama and Brazil, India, New Zealand, China, and most of Europe—bringing to life stories and facts about the trees around us: how they grow old, how they eat and reproduce, how they talk to one another (and they do), and why they came to exist in the first place. He considers the pitfalls of being tall; the things that trees produce, from nuts and rubber to wood; and even the complicated debt that we as humans owe them.Tudge takes us to the Amazon in flood, when the water is deep enough to submerge the forest entirely and fish feed on fruit while river dolphins race through the canopy. He explains the “memory” of a tree: how those that have been shaken by wind grow thicker and sturdier, while those attacked by pests grow smaller leaves the following year; and reveals how it is that the same trees found in the United States are also native to China (but not Europe).From tiny saplings to centuries-old redwoods and desert palms, from the backyards of the American heartland to the rain forests of the Amazon and the bamboo forests, Colin Tudge takes the reader on a journey through history and illuminates our ever-present but often ignored companions. A blend of history, science, philosophy, and environmentalism, The Tree is an engaging and elegant look at the life of the tree and what modern research tells us about their future.

    But as a new century approached, appetites broadened, and David Fairchild, a young botanist with an insatiable lust to explore and experience the world, set out in search of foods that would enrich the American farmer and enchant the American eater.Kale from Croatia, mangoes from India, and hops from Bavaria. Peaches from China, avocados from Chile, and pomegranates from Malta. Fairchild's finds weren't just limited to food: From Egypt he sent back a variety of cotton that revolutionized an industry, and via Japan he introduced the cherry blossom tree, forever brightening America's capital. Along the way, he was arrested, caught diseases, and bargained with island tribes. But his culinary ambition came during a formative era, and through him, America transformed into the most diverse food system ever created.

    Fathoms: The World in the Whale blends natural history, philosophy, and science to explore: How do whales experience ecological change? Will our connection to these storied animals be transformed by technology? What can observing whales teach us about the complexity, splendour, and fragility of life? In Fathoms, we learn about whales so rare they have never been named, whale songs that sweep across hemispheres in annual waves of popularity, and whales that have modified the chemical composition of our planet’s atmosphere. We travel to Japan to board the ships that hunt whales and delve into the deepest seas to discover the plastic pollution now pervading the whale’s undersea environment. In the spirit of Rachel Carson and Rebecca Solnit, Giggs gives us a vivid exploration of the natural world even as she addresses what it means to write about nature at a time of environmental crisis.

    From distressed small communities in Central Appalachia to wealthy suburbs; from disparate cities to once-idyllic farm towns; it's a heartbreaking trajectory that illustrates how this national crisis has persisted for so long and become so firmly entrenched. Beginning with a single dealer who lands in a small Virginia town and sets about turning high school football stars into heroin overdose statistics, Macy endeavors to answer a grieving mother's question-why her only son died-and comes away with a harrowing story of greed and need. From the introduction of OxyContin in 1996, Macy parses how America embraced a medical culture where overtreatment with painkillers became the norm. In some of the same distressed communities featured in her bestselling book Factory Man, the unemployed use painkillers both to numb the pain of joblessness and pay their bills, while privileged teens trade pills in cul-de-sacs, and even high school standouts fall prey to prostitution, jail, and death.Through unsparing, yet deeply human portraits of the families and first responders struggling to ameliorate this epidemic, each facet of the crisis comes into focus. In these politically fragmented times, Beth Macy shows, astonishingly, that the only thing that unites Americans across geographic and class lines is opioid drug abuse. But in a country unable to provide basic healthcare for all, Macy still finds reason to hope-and signs of the spirit and tenacity necessary in those facing addiction to build a better future for themselves and their families.