Organized conceptually around the major fields of medical endeavour - anatomy, physiology, pathology, pharmacology, surgery, obstetrics, psychiatry, pediatrics, and family medicine - this book is an accessible overview of medical history as a vibrant component of social, intellectual, and cultural history, and as a research discipline in its own right.Each chapter begins in antiquity and ends in the twentieth century. Throughout, Duffin shows that alternative interpretations can be found for most elements of our past and that topics of interest can go well beyond 'great men' and 'great discoveries' to include ideas, diseases, patients, institutions, and great mistakes. This approach does not mean that the 'great men' (and women) are neglected; rather they appear in context. Medical disasters such as chloramphenicol and thalidomide, are covered along with the triumphs, and examples from Canada's past, largely ignored in other medical histories, are included. A chapter on methodology, suggestions for further reading with special attention to Canadian sources, and a careful index make it possible to research a specific event or historical debate, or to satisfy a more general curiosity.By presenting the material in a structure that resonates with the broad outlines of medical training, and by focusing on the questions asked most often, this text is a relevant guide for students to the history of the profession they are about to embrace, and for those who would teach them, be they physicians or historians. Duffin's clear and entertaining prose and the many illustrations will help to demystify medicine for general readers and for students in other domains, such as history, philosophy, and sociology.

    President Trump blames the "deep state" for his impeachment. But what is the American "deep state" and does it really exist?To conservatives, the “deep state” is an ever-growing government bureaucracy, an "administrative state" that relentlessly encroaches on the individual rights of Americans. Liberals fear the "military-industrial complex"—a cabal of generals and defense contractors who they believe routinely push the country into endless wars. Every modern American president—from Carter to Trump—has engaged in power struggles with Congress, the CIA, and the FBI. Every CIA and FBI director has suspected White House aides of members of Congress of leaking secrets for political gain. Frustrated Americans increasingly distrust the politicians, unelected officials, and journalists who they believe unilaterally set the country’s political agenda. American democracy faces its biggest crisis of legitimacy in a half century.This sweeping exploration examines the CIA and FBI scandals of the past fifty years, from the Church Committee’s exposure of Cold War abuses, to Abscam, to false intelligence about Iraq’s weapons of mass destruction, to NSA mass surveillance revealed by Edward Snowden. It then investigates the claims and counterclaims of the Trump era, and the relentless spread of conspiracy theories online and on-air. While Trump says he is the victim of the "deep state," Democrats accuse the president and his allies of running a de facto "deep state" of their own that operates outside official government channels and smears rivals, both real and perceived.The feverish debate over the "deep state" raises core questions about the future of American democracy. Is it possible for career government officials to be politically neutral? Was Congress’s impeachment of Donald Trump conducted properly? How vast should the power of a president be? Based on dozens of interviews with career CIA operatives and FBI agents, In Deep answers whether the FBI, CIA, or politicians are protecting or abusing the public’s trust.

    This is a disturbing, well-researched wake-up call for improving the current system of drug supply and manufacturing.Several decades ago, penicillin, vitamin C, and many other prescription and over-the-counter products were manufactured in the United States. But with the rise of globalization, antibiotics, antidepressants, birth control pills, blood pressure medicines, cancer drugs, among many others are made in China and sold in the United States. China's biggest impact on the US drug supply is making essential ingredients for thousands of medicines found in American homes and used in hospital intensive care units and operating rooms. The authors convincingly argue that there are at least two major problems with this scenario. First, it is inherently risky for the United States to become dependent on any one country as a source for vital medicines, especially given the uncertainties of geopolitics. For example, if an altercation in the South China Sea causes military personnel to be wounded, doctors may rely upon medicines with essential ingredients made by the adversary. Second, lapses in safety standards and quality control in Chinese manufacturing are a risk. Citing the concerns of FDA officials and insiders within the pharmaceutical industry, the authors document incidents of illness and death caused by contaminated medications that prompted reform. This probing book examines the implications of our reliance on China on the quality and availability of vital medicines.

    Psych 101 cuts out the boring details and statistics, and instead, gives you a lesson in psychology that keeps you engaged - and your synapses firing.From personality quizzes and the Rorschach Blot Test to B.F. Skinner and the stages of development, this primer for human behavior is packed with hundreds of entertaining psychology basics and quizzes you can't get anywhere else.So whether you're looking to unravel the intricacies of the mind, or just want to find out what makes your friends tick, Psych 101 has all the answers - even the ones you didn't know you were looking for.

    Backed by investors such as Larry Ellison and Tim Draper, Theranos sold shares in a fundraising round that valued the company at $9 billion, putting Holmes's worth at an estimated $4.7 billion. There was just one problem: The technology didn't work.For years, Holmes had been misleading investors, FDA officials, and her own employees. When Carreyrou, working at The Wall Street Journal, got a tip from a former Theranos employee and started asking questions, both Carreyrou and the Journal were threatened with lawsuits. Undaunted, the newspaper ran the first of dozens of Theranos articles in late 2015. By early 2017, the company's value was zero and Holmes faced potential legal action from the government and her investors. Here is the riveting story of the biggest corporate fraud since Enron, a disturbing cautionary tale set amid the bold promises and gold-rush frenzy of Silicon Valley.

    Administered off-label in small daily doses (0.5 to 4.5 mg), this generic drug is extremely affordable and presents few known side effects. So why has it languished in relative medical obscurity? The LDN Book explains the drug’s origins, its primary mechanism, and the latest research from practicing physicians and pharmacists as compiled by Linda Elsegood of The LDN Research Trust, the world’s largest LDN charity organization with over 19,000 members worldwide. Featuring ten chapters contributed by medical professionals on LDN’s efficacy and two patient-friendly appendices, The LDN Book is a comprehensive resource for doctors, pharmacists, and patients who want to learn more about how LDN is helping people now, and a clarion call for further research that could help millions more.

    Dominic Pimenta encountered his first suspected case of coronavirus. Within a week, he began wearing a mask on the tube and within a month, he was moved over to the Intensive Care Unit to help fight this virus.'DUTY OF CARE' is the first book to tell the full story of the COVID-19 pandemic from someone on the frontline, working in one of NHS's hardest hit areas. From the initial whispers coming out of China and the collective hesitation to class this as a pandemic to full lockdown and the continued battle to treat whoever came through the doors. Dr. Pimenta tells the heroic stories of how the entire system shifted to tackle this outbreak and how, ultimately, the staff managed to save lives.KINDLE AND PAPERBACK ⇒ 320 pagesAUDIBLE RUNNING TIME ⇒ 10hrs. and 4mins.©2020 Dr. Dominic Pimenta (P)2020 W.F. Howes Ltd

    Martin A. Lee traces the dramatic social history of marijuana from its origins to its emergence in the 1960s as a defining force in a culture war that has never ceased. Lee describes how the illicit marijuana subculture overcame government opposition and morphed into a dynamic, multibillion-dollar industry. In 1996, California voters approved Proposition 215, legalizing marijuana for medicinal purposes. Similar laws have followed in more than a dozen other states, but not without antagonistic responses from federal, state, and local law enforcement. Lee, an award-winning investigative journalist, draws attention to underreported scientific breakthroughs that are reshaping the therapeutic landscape. By mining the plant’s rich pharmacopoeia, medical researchers have developed promising treatments for cancer, heart disease, Alzheimer’s, diabetes, chronic pain, and many other conditions that are beyond the reach of conventional cures.Colorful, illuminating, and at times irreverent, this is a fascinating read for recreational users and patients, students and doctors, musicians and accountants, Baby Boomers and their kids, and anyone who has ever wondered about the secret life of this ubiquitous herb. Smoke Signals is the winner of the American Botanical Council's James A. Duke Excellence in Botanical Literature Award for 2012

    Based on the latest scientific discoveries, Dr Mosley provides a fascinating and detailed understanding of the secrets of this coronavirus, how it spreads, how it infects your body and how your immune system tries to fight back. With access to leading experts, he reports on the battle to find treatments and a safe and effective vaccine (ultimately, the only way to defeat the virus). Armed with the facts about Covid-19 you'll be in a better position to protect yourself and your family as the world begins to reopen. Eating well, sleeping soundly, exercising and managing stress are all vital for keeping your body and immune system in the best possible shape to fight the virus. These are areas where Dr Mosley, creator of the 5:2 diet, is well known for his science-based and practical approach.

    Why does music evoke such powerful moods? The answers are at last be- coming clear, thanks to revolutionary neuroscience and the emerging field of evolutionary psychology. Both a cutting-edge study and a tribute to the beauty of music itself, This Is Your Brain on Music unravels a host of mysteries that affect everything from pop culture to our understanding of human nature, including: • Are our musical preferences shaped in utero? • Is there a cutoff point for acquiring new tastes in music? • What do PET scans and MRIs reveal about the brain’s response to music? • Is musical pleasure different from other kinds of pleasure?This Is Your Brain on Music explores cultures in which singing is considered an essential human function, patients who have a rare disorder that prevents them from making sense of music, and scientists studying why two people may not have the same definition of pitch. At every turn, this provocative work unlocks deep secrets about how nature and nurture forge a uniquely human obsession.

    Letters sent surreptitiously from a mailbox in New Jersey to media and political figures in New York, Florida, and Washington D.C. killed five people and infected seventeen others. For years, the case remained officially unsolved—and it consumed the FBI and became a rallying point for launching the Iraq War. Far from Baghdad, at Fort Detrick, Maryland, stood Bruce Ivins: an accomplished microbiologist at work on patenting a next-generation anthrax vaccine. Ivins, it turned out, also was a man the FBI consulted frequently to learn the science behind the attacks.The Mirage Man reveals how this seemingly harmless if eccentric scientist hid a sinister secret life from his closest associates and family, and how the trail of genetic and circumstantial evidence led inexorably to him. Along the way, Willman exposes the faulty investigative work that led to the public smearing of the wrong man, Steven Hatfill, a scientist specializing in biowarfare preparedness whose life was upended by media stakeouts and op-ed-page witch hunts. Engrossing and unsparing, The Mirage Man is a portrait of a deeply troubled scientist who for more than twenty years had unlimited access to the U.S. Army’s stocks of deadly anthrax. It is also the story of a struggle for control within the FBI investigation, the missteps of an overzealous press, and how a cadre of government officials disregarded scientific data while spinning the letter attacks into a basis for war. As The Mirage Man makes clear, America must, at last, come to terms with the lessons to be learned from what Bruce Ivins wrought.  The nation’s security depends on it.

    The book is suitable for use as a text in similar overview courses about genes and social issues or genes and disease. It gives a good overview of the developments and status of this field for a wide range of biomedical researchers, physicians, and students, especially those interested in the prospects for the new, genetics-based personalized medicine.

    Some of these drugs are truly transformative, offering major improvements in how long patients live or how they feel--but what is often missing from the popular narrative is that, far too often, these new drugs have marginal or minimal benefits. Some are even harmful. In Malignant, hematologist-oncologist Dr. Vinayak K. Prasad writes about the many sobering examples of how patients are too often failed by cancer policy and by how oncology is practiced. Throughout this work, Prasad illuminates deceptive practices which- promote novel cancer therapies long before credible data are available to support such treatment; and- exaggerate the potential benefits of new therapies, many of which cost thousands and in some cases hundreds of thousands of dollars.Prasad then critiques the financial conflicts of interest that pervade the oncology field, the pharmaceutical industry, and the US Food and Drug administration.This is a book about how the actions of human beings--our policies, our standards of evidence, and our drug regulation--incentivize the pursuit of marginal or unproven therapies at lofty and unsustainable prices. Prasad takes us through how cancer trials are conducted, how drugs come to market, and how pricing decisions are made, asking how we can ensure that more cancer drugs deliver both greater benefit and a lower price. Ultimately, Prasad says,- more cancer clinical trials should measure outcomes that actually matter to people with cancer;- patients on those trials should look more like actual global citizens;- we need drug regulators to raise, not perpetually lower, the bar for approval; and- we need unbiased patient advocates and experts.This well-written, opinionated, and engaging book explains what we can do differently to make serious and sustained progress against cancer--and how we can avoid repeating the policy and practice mistakes of the past.

    Updated to reflect all critical new developments in drug action and drug-disease interaction. This is the desert island book of all medical pharmacology - if you can own just one pharmacology book, this is it.

    For the first time, medical knowledge took on a precision that had formerly belonged only to mathematics. The body became something that could be mapped. Disease became subject to new rules of classification. And doctors begin to describe phenomena that for centuries had remained below the threshold of the visible and expressible.In The Birth of the Clinic the philosopher and intellectual historian who may be the true heir to Nietzsche charts this dramatic transformation of medical knowledge. As in his classic Madness and Civilization, Michel Foucault shows how much what we think of as pure science owes to social and cultural attitudes — in this case, to the climate of the French Revolution. Brilliant, provocative, and omnivorously learned, his book sheds new light on the origins of our current notions of health and sickness, life and death.