Unusually for Agatha Christie it was a horror short story which is not normally associated with the Great Author. The story was retrieved from the Italian Magazine on the 19th June 2013 and is only 9 pages in length. In normal circumstances, nine pages is not enough to justify a printed version of this little known and recently discovered Agatha Christie work. This book attempts to celebrate the fact that a 'new' work by the Great Author has been discovered and the fact that it can be classified as a horror short story adds to what we know about the Great Lady. The book gives some background to the story in addition to faithfully reproducing the actual Italian translation from the magazine. The English translation follows and the ends with further reference to ensure a full understanding of the story.

    Radiation: What could go wrong? In short, plenty. From Marie Curie carrying around a vial of radium salt because she liked the pretty blue glow to the large-scale disasters at Chernobyl and Fukushima, dating back to the late nineteenth century, nuclear science has had a rich history of innovative exploration and discovery, coupled with mistakes, accidents, and downright disasters. In this lively book, long-time advocate of continued nuclear research and nuclear energy James Mahaffey looks at each incident in turn and analyzes what happened and why, often discovering where scientists went wrong when analyzing past meltdowns. Every incident, while taking its toll, has led to new understanding of the mighty atom—and the fascinating frontier of science that still holds both incredible risk and great promise.

    The outlook was grim. Then she took part in Genentech's clinical trials for a new drug. Five years later she remains cancer-free.Her-2 is the biography of Herceptin, the drug that provoked dramatic responses in Barbara Bradfield and other women in the trials and that offers promise for hundreds of thousands of breast cancer patients. Unlike chemotherapy or radiation, Herceptin has no disabling side effects. It works by inactivating Her-2/neu--a protein that makes cancer cells grow especially quickly-- produced by a gene found in 25 to 30 percent of all breast tumors. Herceptin caused some patients' cancers to disappear completely; in others, it slowed the progression of the disease and gave the women months or years they wouldn't otherwise have had. Herceptin is the first treatment targeted at a gene defect that gives rise to cancer. It marks the beginning of a new era of treatment for all kinds of cancers.Robert Bazell presents a riveting account of how Herceptin was born. Her-2 is a story of dramatic discoveries and strong personalities, showing the combination of scientific investigation, money, politics, ego, corporate decisions, patient activism, and luck involved in moving this groundbreaking drug from the lab to a patient's bedside. Bazell's deft portraits introduce us to the remarkable people instrumental in Herceptin's history, including Dr. Dennis Slamon, the driven UCLA oncologist who played the primary role in developing the treatment; Lily Tartikoff, wife of television executive Brandon Tartikoff, who tapped into Hollywood money and glamour to help fund Slamon's research; and Marti Nelson, who inspired the activists who lobbied for a "compassionate use" program that would allow women outside the clinical trials to have access to the limited supplies of Herceptin prior to FDA approval of the drug. And throughout there are the stories of the heroic women with advanced breast cancer who volunteered for the trials, risking what time they had left on an unproven treatment. Meticulously researched, written with clarity and compassion, Her-2 is masterly reporting on cutting-edge science.

    Drawing on exclusive accounts from whistleblowers and regulators, as well as thousands of pages of confidential FDA documents, Eban reveals an industry where fraud is rampant, companies routinely falsify data, and executives circumvent almost every principle of safe manufacturing to minimize cost and maximize profit, confident in their ability to fool inspectors. Meanwhile, patients unwittingly consume medicine with unpredictable and dangerous effects.The story of generic drugs is truly global. It connects middle America to China, India, sub-Saharan Africa and Brazil, and represents the ultimate litmus test of globalization: what are the risks of moving drug manufacturing offshore, and are they worth the savings? A decade-long investigation with international sweep, high-stakes brinkmanship and big money at its core, Bottle of Lies reveals how the world’s greatest public-health innovation has become one of its most astonishing swindles.

    What ensues when soaring temperatures, rising sea levels, drought, and mass migrations disrupt the global governmental and economic regimes? The Great Collapse of 2093.This work is an important title that will change how readers look at the world. Dramatizing climate change in ways traditional nonfiction cannot, this inventive, at times humorous work reasserts the importance of scientists and the work they do and reveals the self-serving interests of the so called "carbon industrial complex" that have turned the practice of sound science into political fodder. The authors conclude with a critique of the philosophical frameworks, most notably neo-liberalism, that do their part to hasten civilization's demise.Based on sound scholarship yet unafraid to tilt at sacred cows in both science and policy, this book provides a welcome moment of clarity amid the cacophony of climate change literature. It includes a lexicon of historical and scientific terms that enriches the narrative and an interview with the authors.

    In 1614, Hungarian countess Elizabeth Báthory died, sealed in a tiny closet in her castle. Her crimes? She was rumored to have bathed in the blood of her victims, which may have numbered in the hundreds. More recently, Russia’s Andrei Chikatilo, the United States’ Ted Bundy, and Great Britain’s Peter Sutcliffe added to the horrors humans inflict upon their fellow man. Featuring maps, callouts, and facts that follow these criminals’ trails of crime, Evil is a groundbreaking volume. It explores some of the most famous crime cases of real-life murder and mayhem.In this epic account of history’s most infamous murder cases, leading true-crime researcher and writer Colin Wilson teams up with his son Damon Wilson to masterfully recount the shocking details of more than sixty cases of murder and mayhem. Illustrated with hundreds of color and black-and-white photos, Evil features images of criminals, forensic evidence, and key personalities and places that put each crime in historical context.In a continuing search for the meaning in murder, the Wilsons create one of the definitive books in the field of criminology.

    Focusing on the environmental debate on the principle of common commitment, Gingrich and Maple declare a need for bipartisan environmentalism as they call for a new era of environmental stewardship, one with principles that they believe most Americans will share.

    While this has had the positive effect of equalizing access to knowledge, it also has lowered the bar on what depth of knowledge is required to consider oneself an "expert." A cult of anti-expertise sentiment has coincided with anti-intellectualism, resulting in massively viral yet poorly informed debates ranging from the anti-vaccination movement to attacks on GMOs. This surge in intellectual egalitarianism has altered the landscape of debates-all voices are equal, and "fact" is a subjective term. Browsing WebMD puts one on equal footing with doctors, and Wikipedia allows all to be foreign policy experts, scientists, and more. As Tom Nichols shows in The Death of Expertise, there are a number of reasons why this has occurred-ranging from easy access to Internet search engines to a customer satisfaction model within higher education. The product of these interrelated trends, Nichols argues, is a pervasive distrust of expertise among the public coinciding with an unfounded belief among non-experts that their opinions should have equal standing with those of the experts. The experts are not always right, of course, and Nichols discusses expert failure. The crucial point is that bad decisions by experts can and have been effectively challenged by other well-informed experts. The issue now is that the democratization of information dissemination has created an army of ill-informed citizens who denounce expertise.When challenged, non-experts resort to the false argument that the experts are often wrong. Though it may be true, but the solution is not to jettison expertise as an ideal; it is to improve our expertise. Nichols is certainly not opposed to information democratization, but rather the enlightenment people believe they achieve after superficial internet research. He shows in vivid detail the ways in which this impulse is coursing through our culture and body politic, but the larger goal is to explain the benefits that expertise and rigorous learning regimes bestow upon all societies.

    In How to Clone a Mammoth, Beth Shapiro, evolutionary biologist and pioneer in "ancient DNA" research, walks readers through the astonishing and controversial process of de-extinction. From deciding which species should be restored, to sequencing their genomes, to anticipating how revived populations might be overseen in the wild, Shapiro vividly explores the extraordinary cutting-edge science that is being used--today--to resurrect the past. Journeying to far-flung Siberian locales in search of ice age bones and delving into her own research--as well as those of fellow experts such as Svante Paabo, George Church, and Craig Venter--Shapiro considers de-extinction's practical benefits and ethical challenges. Would de-extinction change the way we live? Is this really cloning? What are the costs and risks? And what is the ultimate goal?Using DNA collected from remains as a genetic blueprint, scientists aim to engineer extinct traits--traits that evolved by natural selection over thousands of years--into living organisms. But rather than viewing de-extinction as a way to restore one particular species, Shapiro argues that the overarching goal should be the revitalization and stabilization of contemporary ecosystems. For example, elephants with genes modified to express mammoth traits could expand into the Arctic, re-establishing lost productivity to the tundra ecosystem.Looking at the very real and compelling science behind an idea once seen as science fiction, How to Clone a Mammoth demonstrates how de-extinction will redefine conservation's future.

    Le Guin retells the story of human origin by redefining technology as a cultural carrier bag rather than a weapon of domination.Hacking the linear, progressive mode of the Techno-Heroic, the Carrier Bag Theory of human evolution proposes: 'before the tool that forces energy outward, we made the tool that brings energy home.' Prior to the preeminence of sticks, swords and the Hero's long, hard, killing tools, our ancestors' greatest invention was the container: the basket of wild oats, the medicine bundle, the net made of your own hair, the home, the shrine, the place that contains whatever is sacred. The recipient, the holder, the story. The bag of stars.This influential essay opens a portal to terra ignota: unknown lands where the possibilities of human experience and knowledge can be discovered anew.With a new introduction by Donna Haraway, the eminent cyberfeminist, author of the revolutionary A Cyborg Manifesto and most recently, Staying with the Trouble and Manifestly Haraway. With images by Lee Bul, a leading South Korean feminist artist who had a retrospective at London's Hayward Gallery in 2018.

    Khan was the world's leading black market dealer in nuclear technology, described by a former CIA Director as at least as dangerous as Osama bin Laden. A hero in Pakistan and revered as the Father of the Bomb, Khan built a global clandestine network that sold the most closely guarded nuclear secrets to Iran, North Korea, and Libya.Here for the first time is the riveting inside story of the rise and fall of A.Q. Khan and his role in the devastating spread of nuclear technology over the last thirty years. Drawing on exclusive interviews with key players in Islamabad, London, and Washington, as well as with members of Khan's own network, BBC journalist Gordon Corera paints a truly unsettling picture of the ultimate arms bazaar. Corera reveals how Khan operated within a world of shadowy deals among rogue states and how his privileged position in Pakistan provided him with the protection to build his unique and deadly business empire. It explains why and how he was able to operate so freely for so many years. Brimming with revelations, the book provides new insight into Iran's nuclear ambitions and how close Tehran may be to the bomb.In addition, the book contains startling new information on how the CIA and MI6 penetrated Khan's network, how the U.S. and UK ultimately broke Khan's ring, and how they persuaded Pakistan's President Musharraf to arrest a national hero. The book also provides the first detailed account of the high-wire dealings with Muammar Gadaffi, which led to Libya's renunciation of nuclear weapons and which played a key role in Khan's downfall.The spread of nuclear weapons technology around the globe presents the greatest security challenge of our time. Shopping for Bombs presents a unique window into the challenges of stopping a new nuclear arms race, a race that A.Q. Khan himself did more than any other individual to promote.

    It is also a wakeup call about the dubious origins of food labeled organic. After eating some suspect organic walnuts that supposedly were produced in Kazakhstan, veteran journalist Peter Laufer chooses a few items from his home pantry and traces their origins back to their source. Along the way he learns how easily we are tricked into taking “organic” claims at face value.With organic foods readily available at supermarket chains, confusion and outright deception about labels have become commonplace. Globalization has allowed food from highly corrupt governments and businesses overseas to pollute the organic market with food that is anything but. The organic environment is like the Wild West: oversight is virtually nonexistent, and deception runs amok. Laufer investigates so-called organic farms in Europe and South America as well as in his own backyard in the Pacific Northwest.The book examines what constitutes organic and by whom the definitions are made. The answers will stun readers, who have been sold a questionable, highly suspect, and even false bill of goods for years.

    Belknap's Waterproof Grand Canyon River Guide (All New Color Edition)

    Authors Greg Bear (Eon) and Timothy Zahn (The Last Command) provide non-stop, heart-pounding action that will keep readers on edge until the final page.

    Sherwin Nuland, “a gifted and deeply intelligent writer” (San Francisco Chronicle), combines knowledge, compassion, and elegance of expression to shed light on the workings of our bodies from the perspective of a surgeon. Dr. Nuland recounts age-old legends about the functions and "personalities" of the body's organs and, in riveting vignettes of the surgery he has performed, he describes the connections between myth and reality. A brilliant blend of science and folklore, The Mysteries Within reveals the enigmas not only of the body but also of the human imagination.