They attracted followers ranging from Thomas Jefferson, who laid out mastodon bones on the White House floor, to twentieth-century doctors who used their knowledge of new species to conquer epidemic diseases. Acclaimed science writer Richard Conniff brings these daredevil "species seekers" to vivid life. Alongside their globe-spanning tales of adventure, he recounts some of the most dramatic shifts in the history of human thought. At the start, everyone accepted that the Earth had been created for our benefit. We weren't sure where vegetable ended and animal began, we couldn't classify species, and we didn't understand the causes of disease. But all that changed as the species seekers introduced us to the pantheon of life on Earth—and our place within it.

    Improper use of antibiotics. Local warfare. Massive refugee migration. Changing social and environmental conditions around the world have fostered the spread of new and potentially devastating viruses and diseases—HIV, Lassa, Ebola, and others. Laurie Garrett takes you on a fifty-year journey through the world's battles with microbes and examines the worldwide conditions that have culminated in recurrent outbreaks of newly discovered diseases, epidemics of diseases migrating to new areas, and mutated old diseases that are no longer curable. She argues that it is not too late to take action to prevent the further onslaught of viruses and microbes, and offers possible solutions for a healthier future.

    Random genetic mutation, long believed to be the main source of variation, is only a marginal factor. As the authors demonstrate in this book, the more important source of speciation, by far, is the acquisition of new genomes by symbiotic merger. The result of thirty years of delving into a vast, mostly arcane literature, this is the first book to go beyond -- and reveal the severe limitations of -- the "Modern Synthesis" that has dominated evolutionary biology for almost three generations. Lynn Margulis, whom E. O. Wilson called "one of the most successful synthetic thinkers in modern biology," and her co-author Dorion Sagan have written a comprehensive and scientifically supported presentation of a theory that directly challenges the assumptions we hold about the variety of the living world.

    Contributions from Michael Pollan, Andrew Weil, Eugenia Bone, and many more experts make Fantastic Fungi an awe-inspiring visual journey through the exotic, little-known realm of fungi and its amazing potential to positively influence our lives.An all-star team of professional and amateur mycologists, artists, foodies, ecologists, doctors, and explorers joined forces with time-lapse master Louie Schwartzberg to create Fantastic Fungi, the life-affirming, mind-bending film about mushrooms and their mysterious interwoven rootlike filaments called mycelium. What this team reveals will blow your mind and possibly save the planet. This visually compelling companion book of the same name, edited by preeminent mycologist Paul Stamets, will expand upon the film in every way through extended transcripts, new essays and interviews, and additional facts about the fantastic realm of fungi.Fantastic Fungi is at the forefront of a mycological revolution that is quickly going mainstream. In this book, learn about the incredible communication network of mycelium under our feet, which has the proven ability to restore the planet’s ecosystems, repair our health, and resurrect our symbiotic relationship with nature. Fantastic Fungi aspires to educate and inspire the reader in three critical areas: First, the text showcases research that reveals mushrooms as a viable alternative to Western pharmacology. Second, it explores studies pointing to mycelium as a solution to our gravest environmental challenges. And, finally, it details fungi’s marvelous proven ability to shift consciousness. Motivating both the visually stunning film and this follow-up book is an urgent mission to change human consciousness and restore our planet.

    Saxons, Vikings, and Celts, which resulted from a systematic ten-year DNA survey of more than 10,000 volunteers, traces the true genetic makeup of the British Isles and its descendants, taking readers from the Pontnewydd cave in North Wales to the resting place of "The Red Lady" of Paviland and the tomb of King Arthur. Genealogy has become a popular pastime of Americans interested in their heritage, and this is the perfect work for anyone interested in finding their heritage in England, Scotland, or Ireland.

    You may think you know your cat as he purrs in your lap, but come across your pet in the street on a dark night and you might think that Bagpuss suffers from a dual personality.Every single feline pet carries an inheritance of amazing sensory capacities, vocal utterances, body language and territorial displays. By answering such questions as 'what does a cat signal with its ears? 'why does a cat rub up against your leg?' and 'why does a cat swing its head from side to side when staring at its prey?', Desmond Morris decodes the private world of the cat.Your cat is full of surprises and our finest zoologist is about to reveal their secrets in this beautifully repackaged edition of a much loved bestseller.

    At the time, Watson was only 24, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science's greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions & bitter rivalries. With humility unspoiled by false modesty, Watson relates his & Crick's desperate efforts to beat Linus Pauling to the Holy Grail of life sciences, the identification of the basic building block of life. Never has a scientist been so truthful in capturing in words the flavor of his work.

    Born and raised in a small town, they enjoy a close relationship, though each has her own tastes and personality. But the Hensels also share a body. Their two heads sit side-by-side on a single torso, with two arms and two legs. They have not only survived, but have developed into athletic, graceful young women. And that, writes Mark S. Blumberg, opens an extraordinary window onto human development and evolution.In Freaks of Nature, Blumberg turns a scientist's eye on the oddities of nature, showing how a subject once relegated to the sideshow can help explain some of the deepest complexities of biology. Why, for example, does a two-headed human so resemble a two-headed minnow? What we need to understand, Blumberg argues, is that anomalies are the natural products of development, and it is through developmental mechanisms that evolution works. Freaks of Nature induces a kind of intellectual vertigo as it upends our intuitive understanding of biology. What really is an anomaly? Why is a limbless human a freak, but a limbless reptile-a snake-a successful variation?What we see as deformities, Blumberg writes, are merely alternative paths for development, which challenge both the creature itself and our ability to fit it into our familiar categories. Rather than mere dead-ends, many anomalies prove surprisingly survivable-as in the case of the goat without forelimbs that learned to walk upright. Blumberg explains how such variations occur, and points to the success of the Hensel sisters and the goat as examples of the extraordinary flexibility inherent in individual development.In taking seriously a subject that has often been shunned as discomfiting and embarrassing, Mark Blumberg sheds new light on how individuals-and entire species-develop, survive, and evolve.

    She examines the physical basis of our emotions and searches for the answer to one of the most enduring mysteries in modern science: How does the brain create a unique, subjective experience for each one of us?Utilizing cutting-edge research and compelling personal anecdotes, Greenfield reveals that emotions, triggered by individual life experiences, are the very foundation upon which our brains build our unique minds. In this absorbing, lyrical exploration, Dr. Greenfield presents a provocative new theory that provides an illuminating glimpse into the human brain and reveals the astonishing essence of who we are."This is one of those rare books that can make a reader happy to have been led to think."-Booklist

    Some of these drugs are truly transformative, offering major improvements in how long patients live or how they feel--but what is often missing from the popular narrative is that, far too often, these new drugs have marginal or minimal benefits. Some are even harmful. In Malignant, hematologist-oncologist Dr. Vinayak K. Prasad writes about the many sobering examples of how patients are too often failed by cancer policy and by how oncology is practiced. Throughout this work, Prasad illuminates deceptive practices which- promote novel cancer therapies long before credible data are available to support such treatment; and- exaggerate the potential benefits of new therapies, many of which cost thousands and in some cases hundreds of thousands of dollars.Prasad then critiques the financial conflicts of interest that pervade the oncology field, the pharmaceutical industry, and the US Food and Drug administration.This is a book about how the actions of human beings--our policies, our standards of evidence, and our drug regulation--incentivize the pursuit of marginal or unproven therapies at lofty and unsustainable prices. Prasad takes us through how cancer trials are conducted, how drugs come to market, and how pricing decisions are made, asking how we can ensure that more cancer drugs deliver both greater benefit and a lower price. Ultimately, Prasad says,- more cancer clinical trials should measure outcomes that actually matter to people with cancer;- patients on those trials should look more like actual global citizens;- we need drug regulators to raise, not perpetually lower, the bar for approval; and- we need unbiased patient advocates and experts.This well-written, opinionated, and engaging book explains what we can do differently to make serious and sustained progress against cancer--and how we can avoid repeating the policy and practice mistakes of the past.

    In Resurrection Science, journalist M. R. O'Connor explores the extreme measures scientists are taking to try and save them, from captive breeding and genetic management to de-extinction. Paradoxically, the more we intervene to save species, the less wild they often become. In stories of sixteenth-century galleon excavations, panther-tracking in Florida swamps, ancient African rainforests, Neanderthal tool-making, and cryogenic DNA banks, O'Connor investigates the philosophical questions of an age in which we play god with earth's biodiversity.Each chapter in this beautifully written book focuses on a unique species--from the charismatic northern white rhinoceros to the infamous passenger pigeon--and the people entwined in the animals' fates. Incorporating natural history and evolutionary biology with conversations with eminent ethicists, O'Connor's narrative goes to the heart of the human enterprise: What should we preserve of wilderness as we hurtle toward a future in which technology is present in nearly every aspect of our lives? How can we co-exist with species when our existence and their survival appear to be pitted against one another?

     It was an ancient puzzle that stymied history's greatest minds: How did the fossils of seashells find their way far inland, sometimes high up into the mountains? Fossils only made sense in a world old enough to form them, and in the seventeenth century, few people could imagine such a thing. Texts no less authoritative than the Old Testament laid out very clearly the timescale of Earth's past; in fact one Anglican archbishop went so far as to calculate the exact date of Creation...October 23, 4004, B.C. A revolution was in the making, however, and it was started by the brilliant and enigmatic Nicholas Steno, the man whom Stephen Jay Gould called "the founder of geology." Steno explored beyond the pages of the Bible, looking directly at the clues left in the layers of the Earth. With his groundbreaking answer to the fossil question, Steno would not only confound the religious and scientific thinking of his own time, he would set the stage for the modern science that came after him. He would open the door to the concept of "deep time," which imagined a world with a history of millions or billions of years. And at the very moment his expansive new ideas began to unravel the Bible's authoritative claim as to the age of the Earth, Steno would enter the priesthood and rise to become a bishop, ultimately becoming venerated as a saint and beatified by the Catholic Church in 1988. Combining a thrilling scientific investigation with world-altering history and the portrait of an extraordinary genius, "The Seashell on the Mountaintop" gives us new insight into the very old planet on which we live, revealing how we learned to read the story told to us by the Earth itself, written in rock and stone.

    Yet we face soaring worldwide rates of obesity, diabetes, high blood pressure, mental illness, heart disease, and stroke. In his fascinating new book, Dr. Lee Goldman presents a radical explanation: The key protective traits that once ensured our species' survival are now the leading global causes of illness and death. Our capacity to store food, for example, lures us into overeating, and a clotting system designed to protect us from bleeding to death now directly contributes to heart attacks and strokes. A deeply compelling narrative that puts a new spin on evolutionary biology, TOO MUCH OF A GOOD THING also provides a roadmap for getting back in sync with the modern world.

    The result is a wealth of stimulating ideas set among clear explanations drawn from a revelatory decade in biology."—Andrew H. Knoll, author of Life on a Young Planet"Thought-provoking and lucidly written. . . . The Plausibility of Life will help readers understand not just the plausibility of evolution, but its remarkable, inventive powers." —Sean Carroll, author of Endless Forms Most Beautiful: The New Science of Evo Devo“Remarkably lucid and comprehensive, this new theoretical synthesis will . . . shift the grounds for debate in the controversy surrounding organic evolution.”—Booklist (starred review)

    And despite the advances of science, germs are challenging medicine in ways that were unimaginable ten years ago. No wonder the world is up in arms -- and using antibacterial soaps. From the common cold, E. coli, and Lyme disease to encephalitis, mad cow disease, and flesh-eating bacteria, Tierno takes readers on a historical survey of the microscopic world. Rebuffing scare tactics behind recent "germ events" Tierno explains how the recycling of matter is the key to life. Yes, he'll tell you why it's a good idea to clean children's toys, why those fluffy towels may not be so clean, and why you never want to buy a second-hand mattress, but he also reveals that there is a lot we can do to prevent germ-induced suffering. You'll never look at anything the same way again.