Chapters cover cancer, infection, immune disorders, genetics, and disorders of each body system, highlighting pathophysiologic processes, resulting signs and symptoms, diagnostic test findings, and current treatments. Reader-friendly features include illustrations, checklists, and full-color miniguides illustrating the pathophysiology of specific disorders.This edition has new full-color miniguides on cancer pathophysiology and neuropathology. A new Focus on Genetics feature identifies gene-related discoveries and their implications for treatment or diagnosis. Review questions and answers follow current NCLEX-RN® requirements and alternate-format questions are included.

     What is it like to be the senior surgeon when a young woman is brought to casualty with a life-threatening bleed? What does the fear of cancer do to a person? Is it ever best not to tell the patient everything? Tender is the Scalpel’s Edge draws on Gautam Das’s real-life experiences working in Britain’s busy NHS hospitals, from the plunging depths of a patient dying on the operating table to the euphoria of a life saved by teamwork and skill. Described in exquisite detail and with extreme sensitivity, Gautam shares his journey from a medical student fighting his own inner demons to a senior NHS consultant surgeon. Shards of his earlier life in India add to the richness of the narrative in tales that observe life with all its contradictions, like the little village boy with bone cancer. While other anecdotes take in the lighter side of life, Tender is the Scalpel’s Edge is written to inform and engross the general reader, as well as those with a curiosity of life behind the surgeon’s mask. Written in a manner similar to other medical biographies including Henry Marsh’s Do No Harm, Atul Gawande’s Being Mortal and When Breath Becomes Air by Paul Kalanithi, Tender is the Scalpel’s Edge is a moving collection of true stories from a professional at the frontline of medical care.

    Over 1,000 Board-style questions, with detailed rationales, cover the most essential, need-to-know concepts in physiology. Includes thorough reviews of all major body systems, with emphasis on system interaction, homeostasis, and pathophysiology.Offers a comprehensive practice exam of over 1,000 questions in USMLE format.Includes answers and explanations for every question, as well as page references to the Guyton & Hall's Textbook of Medical Physiology.Follows a parallel chapter organization to Textbook of Medical Physiology.Provides all of the essential information needed to prepare for the physiology portion of the USMLE Step 1.Dedicates a brief section to helpful hints on preparing for the USMLE exam.

    Arun Singh has witnessed life and death from a vantage point nearly unmatched in medical history, while performing over 15,000 open heart surgeries. Revered by colleagues and patients, under the hot lights of the O.R. this award-winning surgeon has spent thousands of hours performing life-saving operations, while witnessing the miraculous, the joyous, and the devastating. He has held the life-giving heart in his hand and has been praised for his tireless devotion to preserving the lives this organ sustains.Dr. Singh's decorated career is an odyssey of remarkable determination. To illuminate the power of perseverance, Dr. Singh recounts how the same two hands that have so expertly worked to extend life were once crushed and his future nearly shattered. In YOUR HEART, MY HANDS he recalls the fortitude that saw him through a complicated boyhood in India, struggles with dyslexia, and finding his way as an immigrant, to become one of America's most highly-regarded and preeminent surgeons. Reflecting on over 40 years of practice, Dr. Singh shares intimate O.R. secrets, riveting patient accounts, and the life lessons he learned treating his most memorable patients. This book will inspire, enlighten, and captivate readers.

    The 7th edition incorporates the latest advances in molecular diagnostics, the Human Genome Project, and much more. More than 240 dynamic illustrations and high-quality photos help you grasp complex concepts more easily. In addition to the book, you will also receive STUDENT CONSULT, enabling you to access the complete contents of the book online, anywhere you go

    But things didn't turn out that way. For a start, we turned out to have far fewer genes than originally thought - just over 20,000, the same sort of number as a fruit fly or worm. What's more, the proportionof DNA consisting of genes coding for proteins was a mere 2%. So, was the rest of the genome accumulated 'junk'?Things have changed since those early heady days of the Human Genome Project. But the emerging picture is if anything far more exciting. In this book, John Parrington explains the key features that are coming to light - some, such as the results of the international ENCODE programme, still much debated and controversial in their scope. He gives an outline of the deeper genome, involving layers of regulatory elements controlling and coordinating the switching on and off of genes; the impact ofits 3D geometry; the discovery of a variety of new RNAs playing critical roles; the epigenetic changes influenced by the environment and life experiences that can make identical twins different and be passed on to the next generation; and the clues coming out of comparisons with the genomes ofNeanderthals as well as that of chimps about the development our species. We are learning more about ourselves, and about the genetic aspects of many diseases. But in its complexity, flexibility, and ability to respond to environmental cues, the human genome is proving to be far more subtle than we ever imagined.

    High vitality, optimal health and sustainable strength can only be achieved by a properly-informed plan to understand, identify and conquer the enemies of our wellbeing. The only way to sustain a healthy, vigorous life is to make long-term lifestyle changes—across the board, be it through nutrition, resistance training, cardio or stress management. Strong Medicine shows you how to achieve an utter and complete physical and physiological transformation in 3 months without any draconian training or concentration camp nutrition. Discover how to go from unhealthy and uncertain into ever-improving levels of health, wellness and fitness… Using the intersection of cutting-edge science and real-world medicine—melded with high-level athletics, results-producing coaching and elite military-preparedness training… "Strong Medicine is flat-out amazing. If you ever wanted to take your training and your nutritional theory to an elite level—better than 99.9% of certified personal trainers—this is the book for you. It's all in here: genetics, gut bacteria, cutting-edge stress biology, molecular nutrition...even better, the ‘deep science’ is all explained so clearly (with charts, key points, photos and diagrams) that it's almost impossible not to understand and absorb it all fully. An automatic classic in the field, which will surely prove impossible to surpass. I bow down to the Doc and to Marty!"—Paul Wade, author, Convict Conditioning and Explosive Calisthenics “Strong Medicine by Chris Hardy, D.O. and Marty Gallagher is an exhaustively researched, clearly written, and practically useful guide to improving your health. Improving health is fundamentally different than treating disease. This book represents the future of healthcare in our country. It requires the patient to assume responsibility, learn the basics, and then enhance their health through diet, exercise, sleep, and mindfulness. If you are looking for a quick fix, this is not the book for you. If you understand that there is no quick fix, then read this book and trust what you read. The information is accurate and relevant, simple to understand, and actionable.” —Patrick Roth, M.D., author of The End of Back Pain: Access Your Hidden Core to Heal Your Body, Chairman of Neurosurgery at Hackensack University Medical Center and the director of its neurosurgical residency training program. “Strong Medicine by Dr. Chris Hardy and the legendary Marty Gallagher is a declaration of unconventional and asymmetrical war against mortality. The authors' weapon of choice is information, relayed masterfully in the form of an easy-to-understand and richly illustrated owner’s manual of sorts. This is an owner’s manual that is chock full of insights for every level, from the seasoned physician to the absolute layman who is new to fitness. For the grizzled coach who doesn't have medical training, Strong Medicine lays out crucial performance concepts like ‘hormetic dose’ in ways that are easy to understand regardless of your background. Dr. Hardy continues with insights into diet, nutrition myths, biochemistry demystified, intestinal fine-tuning, the chronic stress connection with disease, and then passes the baton to Marty Gallagher, who unleashes a plethora of exercise and training tips that are centered around five basic exercise categorie

    As the mosquito transformed the landscapes of civilization, humans were unwittingly required to respond to its piercing impact and universal projection of power.The mosquito has determined the fates of empires and nations, razed and crippled economies, and decided the outcome of pivotal wars, killing nearly half of humanity along the way. She (only females bite) has dispatched an estimated 52 billion people from a total of 108 billion throughout our relatively brief existence. As the greatest purveyor of extermination we have ever known, she has played a greater role in shaping our human story than any other living thing with which we share our global village.Imagine for a moment a world without deadly mosquitoes, or any mosquitoes, for that matter? Our history and the world we know, or think we know, would be completely unrecognizable.Driven by surprising insights and fast-paced storytelling, The Mosquito is the extraordinary untold story of the mosquito's reign through human history and her indelible impact on our modern world order.

    There have been exhilarating highs and devastating lows, but his love for the practice of neurosurgery has never wavered. Following the publication of his celebrated New York Times bestseller Do No Harm, Marsh retired from his full-time job in England to work pro bono in Ukraine and Nepal. In Admissions, he describes the difficulties of working in these troubled, impoverished countries and the further insights it has given him into the practice of medicine. Marsh also faces up to the burden of responsibility that can come with trying to reduce human suffering. Unearthing memories of his early days as a medical student and the experiences that shaped him as a young surgeon, he explores the difficulties of a profession that deals in probabilities rather than certainties and where the overwhelming urge to prolong life can come at a tragic cost for patients and those who love them. Reflecting on what forty years of handling the human brain has taught him, Marsh finds a different purpose in life as he approaches the end of his professional career and a fresh understanding of what matters to us all in the end.

    Holistic health coach and recovery expert, Joe Baldizzone, knows first-hand what it's like to live with depression and how to recover from debilitating panic, as well as addiction. In this book you will find simple strategies to help you get started on your own path to recovery. Do you feel anxious most of the time? Are you overwhelmed with persistent worries? Is depression keeping you in the house? Have you reached for drugs and alcohol to cope? Are you considering going to see a psychiatrist, but scared of being put on medication? If you're looking to change your life and find happiness without doctors and medications, try the proven methods Joe has to offer. Learn about Joe's recovery and how to use the 50 tools that have helped him as well as countless other people.

    Thanks largely to YouTube clips posted by the sloth orphanage in Costa Rica, sloths have attracted a vast audience of admirers. Instead of seeing them as ridiculous anachronisms of which we know little, they have turned into creatures considered by many to be the most endearing on earth.Over much the same period, scientific investigations have also changed our view of sloths. No longer are they seen as total misfits in the modern world but, in the words of one specialist sloth investigator, they are 'masters of an alternative lifestyle'.In this wonderfully entertaining celebration of this most unique of creatures, William Hartston reveals the fascinating history of the sloth, from the prehistoric ground sloth to modern pygmy sloths in Panama, explores the current state of the science of sloths and reveals the truth behind sloth behaviour.

    Purchasers are entitled to a free trial membership in the General Books Club where they can select from more than a million books without charge. Subjects: Hygiene; Diet; Therapeutics, Physiological; Medical / General; Health

    She is the girl with the blue tattoo.The story behind the distinctive tattoo is the stuff of legends. Some believed it was placed on her face during her captivity, following the brutal murders of her family members and the kidnapping of her and her sister. Others believe it was placed on her after her return.Rumors swelled. Her tattoo became a symbol of Native barbarianism and the triumph of American goodness, but like many stories of that era, the truth is far more complicated.This short book details the murders, her captivity, the aftermath, and her baffling return to her captors. Unravel the mystery of the woman who would become famous for all the wrong reasons and discover what her life story says about cultural identity, the power of resiliency, and what happens when fact and fiction bend and twist to muddy the waters.Read on to find out the truth!

    They all grew up dreaming of skating in the big league as stars. Then one day, a coach tells them the only way to make it is to drop the gloves. And every guy says the same thing: I'll do whatever it takes to play in the NHL.Not Stu Grimson, though. When he was offered a contract to patrol the ice for the Calgary Flames, he said no thanks, and went to university instead. And that's the way Grimson has approached his career and his life: on his own terms. He stared down the toughest players on the planet for seventeen years, while working on his first university degree. He retired on his own terms, and went on to practice law, including a stint as in-house counsel for the NHLPA.This has put him in a unique position when it comes to commenting on the game. He's seen it from the trenches, and he's seen it from the courtroom. This puts him in the eye of the storm surrounding fighting and concussions. And he handles that the way he does everything: on his own terms. When Don Cherry called him out on televison, it was the seemingly indominable Cherry who backed down. Hockey fans will be fascinated by his data-driven defence of fighting.But in the end, this is not a book about fighting and locker-room stories. It's the story of a young man who ultimately took on the toughest role in pro sports and came out the other side. Where many others have not.

    It is high time for humanity to grow up and to transcend itself by embracing transhumanism.Transhumanism offers the most inclusive ideology for all ethnicities and races, the religious and the atheists, conservatives and liberals, the young and the old regardless of socioeconomic status, gender identity, or any other individual qualities. This book expounds on contemporary views and practical advice from more than 70 transhumanists.Astronaut Neil Armstrong said on the Apollo 11 moon landing in 1969, "One small step for a man, one giant leap for mankind." Transhumanism is the next logical step in the evolution of humankind, and it is the existential solution to the long-term survival of the human race.