Backed by investors such as Larry Ellison and Tim Draper, Theranos sold shares in a fundraising round that valued the company at $9 billion, putting Holmes's worth at an estimated $4.7 billion. There was just one problem: The technology didn't work.For years, Holmes had been misleading investors, FDA officials, and her own employees. When Carreyrou, working at The Wall Street Journal, got a tip from a former Theranos employee and started asking questions, both Carreyrou and the Journal were threatened with lawsuits. Undaunted, the newspaper ran the first of dozens of Theranos articles in late 2015. By early 2017, the company's value was zero and Holmes faced potential legal action from the government and her investors. Here is the riveting story of the biggest corporate fraud since Enron, a disturbing cautionary tale set amid the bold promises and gold-rush frenzy of Silicon Valley.

    In No Magic Bullet, Allan M. Brandt recounts the various medical, military, and public health responses that have arisen over the years--a broad spectrum that ranges from the incarceration of prostitutes during World War I to the establishment of required premarital blood tests.Brandt demonstrates that Americans' concerns about venereal disease have centered around a set of social and cultural values related to sexuality, gender, ethnicity, and class. At the heart of our efforts to combat these infections, he argues, has been the tendency to view venereal disease as both a punishment for sexual misconduct and an index of social decay. This tension between medical and moral approaches has significantly impeded efforts to develop magic bullets--drugs that would rid us of the disease--as well as effective policies for controlling the infections' spread.In the paper edition of No Magic Bullet, Brandt adds to his perceptive commentary on the relationship between medical science and cultural values a new chapter on AIDS. Analyzing this latest outbreak in the context of our previous attitudes toward sexually transmitted diseases, he hopes to provide the insights needed to guide us to the policies that will best combat the disease.

    Communities where heroin had never been seen before—from Charlotte, NC and Huntington, WVA, to Salt Lake City and Portland, OR—were overrun with it. Local police and residents were stunned. How could heroin, long considered a drug found only in the dense, urban environments along the East Coast, and trafficked into the United States by enormous Colombian drug cartels, be so incredibly ubiquitous in the American heartland? Who was bringing it here, and perhaps more importantly, why were so many townspeople suddenly eager for the comparatively cheap high it offered?With the same dramatic drive of El Narco and Methland, Sam Quinones weaves together two classic tales of American capitalism: The stories of young men in Mexico, independent of the drug cartels, in search of their own American Dream via the fast and enormous profits of trafficking cheap black-tar heroin to America’s rural and suburban addicts; and that of Purdue Pharma in Stamford, Connecticut, determined to corner the market on pain with its new and expensive miracle drug, Oxycontin; extremely addictive in its own right. Quinones illuminates just how these two stories fit together as cause and effect: hooked on costly Oxycontin, American addicts were lured to much cheaper black tar heroin and its powerful and dangerous long-lasting high. Embroiled alongside the suppliers and buyers are DEA agents, local, small-town sheriffs, and the US attorney from eastern Virginia whose case against Purdue Pharma and Oxycontin made him an enemy of the Bush-era Justice Department, ultimately stalling and destroying his career in public service.Dreamland is a scathing and incendiary account of drug culture and addiction spreading to every part of the American landscape.

    So begins Girl, Edna O'Brien's harrowing portrayal of the young women abducted by Boko Haram. Set in the deep countryside of northeast Nigeria, this is a brutal story of incarceration, horror, and hunger; a hair-raising escape into the manifold terrors of the forest; and a descent into the labyrinthine bureaucracy and hostility awaiting a victim who returns home with a child blighted by enemy blood.

    Eurocentric points of view have dominated the study of this era, but in this book, one of Africa’s leading historians reinterprets the colonial experiences from the perspective of the colonized.

    This House Has Fallen is a bracing and disturbing report on the state of Africa's most populous, potentially richest, and most dangerously dysfunctional nation. Each year, with depressing consistency, Nigeria is declared the most corrupt state in the entire world. Though Nigeria is a nation into which billions of dollars of oil money flow, its per capita income has fallen dramatically in the past two decades. Military coup follows military coup. A bellwether for Africa, it is a country of rising ethnic tensions and falling standards of living, very possibly on the verge of utter collapse -- a collapse that could dramatically overshadow even the massacres in Rwanda. A brilliant piece of reportage and travel writing, This House Has Fallenlooks into the Nigerian abyss and comes away with insight, profound conclusions, and even some hope. Updated with a new preface by the author.

    Purposely flying in the face of decades of safe-sex campaigning and HIV/AIDS awareness initiatives, barebacking is unquestionably radical behavior, behavior that most people would rather condemn than understand. Thus the time is ripe for Unlimited Intimacy, Tim Dean’s riveting investigation into barebacking and the distinctive subculture that has grown around it.Audacious and undeniably provocative, Dean’s profoundly reflective account is neither a manifesto nor an apology; instead, it is a searching analysis that tests the very limits of the study of sex in the twenty-first century. Dean’s extensive research into the subculture provides a tour of the scene’s bars, sex clubs, and Web sites; offers an explicit but sophisticated analysis of its pornography; and documents his own personal experiences in the culture. But ultimately, it is HIV that animates the controversy around barebacking, and Unlimited Intimacy explores how barebackers think about transmitting the virus—especially the idea that deliberately sharing it establishes a new network of kinship among the infected. According to Dean, intimacy makes us vulnerable, exposes us to emotional risk, and forces us to drop our psychological barriers. As a committed experiment in intimacy without limits—one that makes those metaphors of intimacy quite literal—barebacking thus says a great deal about how intimacy works.Written with a fierce intelligence and uncompromising nerve, Unlimited Intimacy will prove to be a milestone in our understanding of sexual behavior.

    Can a person think herself to orgasm? Why doesn't Viagra help women-or, for that matter, pandas? Can a dead man get an erection? Is vaginal orgasm a myth? Mary Roach shows us how and why sexual arousal and orgasm-two of the most complex, delightful, and amazing scientific phenomena on earth-can be so hard to achieve and what science is doing to make the bedroom a more satisfying place.

    Dr. Langston discovered that these people had all used a tainted form of heroin. Using fetal tissue transplant, two of the addicts recovered, garnering world-wide press coverage. This is the story behind the headlines.

    Why then do we have creeping inequality in the land of the fair go? The answer lies in stagnant wage rises, gender pay inequity, insecure work and the lack of real opportunities for all while corporations are still consuming large profits and executives claim record bonuses. Sally McManus confronts these truths every day. In On Fairness, she explores the true cost of social injustice and argues for advancing Australia fair.

    Boyle has spun an even more dazzling tale that will delight both his longtime devotees and a legion of new fans. Boyle’s tenth novel, The Inner Circle has it all: fabulous characters, a rollicking plot, and more sex than pioneering researcher Dr. Alfred Kinsey ever dreamed of documenting . . . well, almost. A love story, The Inner Circle is narrated by John Milk, a virginal young man who in 1940 accepts a job as an assistant to Dr. Alfred Kinsey, an extraordinarily charming professor of zoology at Indiana University who has just discovered his life’s true calling: sex. As a member of Kinsey’s “inner circle” of researchers, Milk (and his beautiful new wife) is called on to participate in sexual experiments that become increasingly uninhibited—and problematic for his marriage. For in his later years Kinsey (who behind closed doors is a sexual enthusiast of the first order) ever more recklessly pushed the boundaries both personally and professionally. While Boyle doesn’t resist making the most of this delicious material, The Inner Circle is at heart a very moving and very loving look at sex, marriage, and jealousy that will have readers everywhere reassessing their own relationships—because, in the end, “love is all there is.”

    Vicky and Charlie are best friends who used to co-review hardcore porn movies. After a year of fat lechers, bored hookers and clunky dialogue, they said, "Hang on, we could make a better film than this ourselves." What was to stop them? Only their conservative families, stammering English reserve, and total lack of experience. They set off at once. This is the extraordinary and hilarious story of their journey from a sofa in North London, through the heart of the sex industry in California, to their own film set in Amsterdam. What happens when a 'nice girl' falls in love with a rent-boy, and a vicar's son attempts to film a gang-bang? Vicky and Charlie learned to see the world through new eyes, and the sex-workers learned how to play cribbage. And together they produced perhaps the most baffling skinflick in history.

    But when her father, the cruel king, sensed an attraction growing between them, he exiled Percival and arranged her marriage with another man. But now, fleeing the castle, Elsa unwittingly runs into Percival’s arms, the man who once guarded her with his life. But Elsa has grown considerably, and things are no longer simple between them, and with her father’s men searching for her, their love could put the fate of the entire kingdom at stake.

    Set mostly in pastoral Entebbe with stops in the cities Kampala and Los Angeles, Tropical Fish depicts the reality of life for Christine Mugisha and her family after Idi Amin's dictatorship.Three of the eight chapters are told from the point of view of Christine's two older sisters, Patti, a born-again Christian who finds herself starving at her boarding school, and Rosa, a free spirit who tries to "magically" seduce one of her teachers. But the star of Tropical Fish is Christine, whom we accompany from her first wobbly steps in high heels, to her encounters with the first-world conveniences and alienation of America, to her return home to Uganda.As the Mugishas cope with Uganda's collapsing infrastructure, they also contend with the universal themes of family cohesion, sex and relationships, disease, betrayal, and spirituality. Anyone dipping into Baingana's incandescent, widely acclaimed novel will enjoy their immersion in the world of this talented newcomer.*Winner of the Commonwealth Writers' Prize for Best First Book in the Africa region*Winner of the Association of Writers and Writing Programs (AWP) Award Series in Short Fiction*Winner of the Washington Writing Prize for Short Fiction *Finalist for the Caine Prize in African Writing

    Anaesthetic Fellow Rory McBride is adrift. Since a routine procedure went horribly wrong, he has been plagued by sleeplessness, flashbacks and escalating panic attacks. Jodi Waterstone has recently started work as a first-year doctor at the same hospital, and the night shifts, impossible workload and endless hours on duty are taking a toll. Both are trying to stay in control of their lives, but Rory starts to self-medicate with sleeping pills and sedatives to help him get through the nights . . . and the days. Before long, the sedatives aren’t enough. Can Jodi save him from himself?