In his capital at Constantinople he built the world's most beautiful building, married its most powerful empress, and wrote its most enduring legal code, seemingly restoring Rome's fortunes for the next five hundred years. Then, in the summer of 542, he encountered a flea. The ensuing outbreak of bubonic plague killed five thousand people a day in Constantinople and nearly killed Justinian himself. In Justinian's Flea, William Rosen tells the story of history's first pandemic plague seven centuries before the Black Death that killed tens of millions, devastated the empires of Persia and Rome, left a path of victims from Ireland to Iraq, and opened the way for the armies of Islam. Weaving together evolutionary microbiology, economics, military strategy, ecology, and ancient and modern medicine, Rosen offers a sweeping narrative of one of the great hinge moments in history, one that will appeal to readers of John Kelly's The Great Mortality, John Barry's The Great Influenza, and Jared Diamond's Collapse .

    Flow spans its fascinating, occasionally wacky and sometimes downright scary story: from mikvahs (ritual cleansing baths) to menopause, hysteria to hysterectomies—not to mention the Pill, cramps, the history of underwear, and the movie about puberty they showed you in 5th grade. Flow answers such questions as: What’s the point of getting a period? What did women do before pads and tampons? What about new drugs that promise to end periods—a hot idea or not? Sex during your period: gross or a turn-on? And what’s normal, anyway?  With color reproductions of (campy) historical ads and early (excruciating) femcare devices, it also provides a fascinating (and mind-boggling) gallery of this complex, personal and uniquely female process. As irreverent as it is informative, Flow gives an everyday occurrence its true props – and eradicates the stigma placed on it for centuries.

    From distressed small communities in Central Appalachia to wealthy suburbs; from disparate cities to once-idyllic farm towns; it's a heartbreaking trajectory that illustrates how this national crisis has persisted for so long and become so firmly entrenched. Beginning with a single dealer who lands in a small Virginia town and sets about turning high school football stars into heroin overdose statistics, Macy endeavors to answer a grieving mother's question-why her only son died-and comes away with a harrowing story of greed and need. From the introduction of OxyContin in 1996, Macy parses how America embraced a medical culture where overtreatment with painkillers became the norm. In some of the same distressed communities featured in her bestselling book Factory Man, the unemployed use painkillers both to numb the pain of joblessness and pay their bills, while privileged teens trade pills in cul-de-sacs, and even high school standouts fall prey to prostitution, jail, and death.Through unsparing, yet deeply human portraits of the families and first responders struggling to ameliorate this epidemic, each facet of the crisis comes into focus. In these politically fragmented times, Beth Macy shows, astonishingly, that the only thing that unites Americans across geographic and class lines is opioid drug abuse. But in a country unable to provide basic healthcare for all, Macy still finds reason to hope-and signs of the spirit and tenacity necessary in those facing addiction to build a better future for themselves and their families.

    On March 27, 1964, at 5:36 p.m., the biggest earthquake ever recorded in North America—and the second biggest ever in the world, measuring 9.2 on the Richter scale—struck Alaska, devastating coastal towns and villages and killing more than 130 people in what was then a relatively sparsely populated region. In a riveting tale about the almost unimaginable brute force of nature, New York Times science journalist Henry Fountain, in his first trade book, re-creates the lives of the villagers and townspeople living in Chenega, Anchorage, and Valdez; describes the sheer beauty of the geology of the region, with its towering peaks and 20-mile-long glaciers; and reveals the impact of the quake on the towns, the buildings, and the lives of the inhabitants. George Plafker, a geologist for the U.S. Geological Survey with years of experience scouring the Alaskan wilderness, is asked to investigate the Prince William Sound region in the aftermath of the quake, to better understand its origins. His work confirmed the then controversial theory of plate tectonics that explained how and why such deadly quakes occur, and how we can plan for the next one.

    Still our nation’s longest running “cold case,” the mystery of Elma Sands finally comes to a close with this book, which delivers the first substantial break in the case in over 200 years.In the closing days of 1799, the United States was still a young republic. Waging a fierce battle for its uncertain future were two political parties: the well-moneyed Federalists, led by Alexander Hamilton, and the populist Republicans, led by Aaron Burr. The two finest lawyers in New York, Burr and Hamilton were bitter rivals both in and out of the courtroom, and as the next election approached—with Manhattan likely to be the swing district on which the presidency would hinge—their animosity reached a crescendo. Central to their dispute was the Manhattan water supply, which Burr saw not just as an opportunity to help a city devastated by epidemics but as a chance to heal his battered finances.But everything changed when Elma Sands, a beautiful young Quaker woman, was found dead in Burr's newly constructed Manhattan Well. The horrific crime quickly gripped the nation, and before long accusations settled on one of Elma’s suitors, handsome young carpenter Levi Weeks. As the enraged city demanded a noose be draped around the accused murderer’s neck, the only question seemed to be whether Levi would make it to trial or be lynched first.The young man’s only hope was to hire a legal dream team. And thus it was that New York’s most bitter political rivals and greatest attorneys did the unthinkable—they teamed up.At once an absorbing legal thriller and an expertly crafted portrait of the United States in the time of the Founding Fathers, Duel with the Devil is a masterpiece of narrative nonfiction.

    During the summer before the United States entered World War I, when ocean swimming was just becoming popular and luxurious Jersey Shore resorts were thriving as a chic playland for an opulent yet still innocent era's new leisure class, Americans were abruptly introduced to the terror of sharks. In July 1916 a lone Great White left its usual deep-ocean habitat and headed in the direction of the New Jersey shoreline. There, near the towns of Beach Haven and Spring Lake-and, incredibly, a farming community eleven miles inland-the most ferocious and unpredictable of predators began a deadly rampage: the first shark attacks on swimmers in U.S. history. For Americans celebrating an astoundingly prosperous epoch much like our own, fueled by the wizardry of revolutionary inventions, the arrival of this violent predator symbolized the limits of mankind's power against nature.Interweaving a vivid portrait of the era and meticulously drawn characters with chilling accounts of the shark's five attacks and the frenzied hunt that ensued, Michael Capuzzo has created a nonfiction historical thriller with the texture of Ragtime and the tension of Jaws. From the unnerving inevitability of the first attack on the esteemed son of a prosperous Philadelphia physician to the spine-tingling moment when a farm boy swimming in Matawan Creek feels the sandpaper-like skin of the passing shark, Close to Shore is an undeniably gripping saga.Heightening the drama are stories of the resulting panic in the citizenry, press and politicians, and of colorful personalities such as Herman Oelrichs, a flamboyant millionaire who made a bet that a shark was no match for a man (and set out to prove it); Museum of Natural History ichthyologist John Treadwell Nichols, faced with the challenge of stopping a mythic sea creature about which little was known; and, most memorable, the rogue Great White itself moving through a world that couldn't conceive of either its destructive power or its moral right to destroy.Scrupulously researched and superbly written, Close to Shore brings to life a breathtaking, pivotal moment in American history. Masterfully written and suffused with fascinating period detail and insights into the science and behavior of sharks, Close to Shore recounts a breathtaking, pivotal moment in American history with startling immediacy.

    She also reveals her personal odyssey through the land of Lyme after she, her husband and their two sons became seriously ill with the disease beginning in the 1990s. From the microbe causing the infection and the definition of the disease, to the length and type of treatment and the kind of practitioner needed, Lyme is a hotbed of contention. With a CDC-estimated 200,000-plus new cases of Lyme disease a year, it has surpassed both AIDS and TB as the fastest-spreading infectious disease in the U.S. Yet alarmingly, in many cases, because the disease often eludes blood tests and not all patients exhibit the classic "bulls-eye" rash and swollen joints, doctors are woefully unable or unwilling to diagnose Lyme. When that happens, once-treatable infections become chronic, inexorably disseminating to cause disabling conditions that may never be cured. Weintraub reveals why the Lyme epidemic has been allowed to explode, why patients are dismissed, and what can be done to raise awareness in the medical community and find a cure. The most comprehensive book ever written about the past, present and future of Lyme disease, this exposes the ticking clock of a raging epidemic.

    They became medical celebrities: every week, eager crowds arrived at the hospital to observe their symptoms; they were photographed, sculpted, painted, and transformed into characters in novels. The remarkable story of their lives as patients in the clinic is a strange amalgam of intimate details and public exposure, science and religion, medicine and the occult, hypnotism, love, and theater. But who were Blanche, Augustine, and Geneviève? What role did they play in their own peculiar form of stardom? And what exactly were they suffering from? Hysteria-with its dramatic seizures, hallucinations, and reenactments of past traumas-may be an illness of the past, but the notions of femininity that lie behind it offer insights into disorders of the present.

    It features a stunning array of personalities, from the women peering worriedly over the side of the Mayflower to feminists having a grand old time protesting beauty pageants and bridal fairs. Courageous, silly, funny, and heartbreaking, these women shaped the nation and our vision of what it means to be female in America. By culling the most fascinating characters — the average as well as the celebrated — Gail Collins, the editorial page editor at the New York Times, charts a journey that shows how women lived, what they cared about, and how they felt about marriage, sex, and work. She begins with the lost colony of Roanoke and the early southern "tobacco brides" who came looking for a husband and sometimes — thanks to the stupendously high mortality rate — wound up marrying their way through three or four. Spanning wars, the pioneering days, the fight for suffrage, the Depression, the era of Rosie the Riveter, the civil rights movement, and the feminist rebellion of the 1970s, America's Women describes the way women's lives were altered by dress fashions, medical advances, rules of hygiene, social theories about sex and courtship, and the ever-changing attitudes toward education, work, and politics. While keeping her eye on the big picture, Collins still notes that corsets and uncomfortable shoes mattered a lot, too. "The history of American women is about the fight for freedom," Collins writes in her introduction, "but it's less a war against oppressive men than a struggle to straighten out the perpetually mixed message about women's roles that was accepted by almost everybody of both genders." Told chronologically through the compelling stories of individual lives that, linked together, provide a complete picture of the American woman's experience, America's Women is both a great read and a landmark work of history.

    In that short time, many doctors decide on the likely diagnosis and best treatment. Often, decisions made this way are correct, but at crucial moments they can also be wrong -- with catastrophic consequences. In this myth-shattering book, Jerome Groopman pinpoints the forces and thought processes behind the decisions doctors make. Groopman explores why doctors err and shows when and how they can -- with our help -- avoid snap judgments, embrace uncertainty, communicate effectively, and deploy other skills that can profoundly impact our health. This book is the first to describe in detail the warning signs of erroneous medical thinking and reveal how new technologies may actually hinder accurate diagnoses. How Doctors Think offers direct, intelligent questions patients can ask their doctors to help them get back on track.Groopman draws on a wealth of research, extensive interviews with some of the country’s best doctors, and his own experiences as a doctor and as a patient. He has learned many of the lessons in this book the hard way, from his own mistakes and from errors his doctors made in treating his own debilitating medical problems.How Doctors Think reveals a profound new view of twenty-first-century medical practice, giving doctors and patients the vital information they need to make better judgments together.

    Ballet dancers and rock musicians, professors and thieves-"anyone who had fallen, or, often, leapt, onto hard times" and needed extended medical care-ended up here. So did Victoria Sweet, who came for two months and stayed for twenty years. Laguna Honda, lower tech but human paced, gave Sweet the opportunity to practice a kind of attentive medicine that has almost vanished. Gradually, the place transformed the way she understood her work. Alongside the modern view of the body as a machine to be fixed, her extraordinary patients evoked an older idea, of the body as a garden to be tended. God's Hotel tells their story and the story of the hospital itself, which, as efficiency experts, politicians, and architects descended, determined to turn it into a modern "health care facility," revealed its own surprising truths about the essence, cost, and value of caring for body and soul.

    In Rats, the critically acclaimed bestseller, Robert Sullivan spends a year investigating a rat-infested alley just a few blocks away from Wall Street. Sullivan gets to know not just the beast but its friends and foes: the exterminators, the sanitation workers, the agitators and activists who have played their part in the centuries-old war between human city dweller and wild city rat. Sullivan looks deep into the largely unrecorded history of the city and its masses-its herds-of-rats-like mob. Funny, wise, sometimes disgusting but always compulsively readable, Rats earns its unlikely place alongside the great classics of nature writing. With an all-new Afterword by the author

    A gripping hour-by-hour account told through the eyes of the hunted and the hunters, this is history as you've never read it before.The murder of Abraham Lincoln set off the greatest manhunt in American history -- the pursuit and capture of John Wilkes Booth. From April 14 to April 26, 1865, the assassin led Union cavalry and detectives on a wild twelve-day chase through the streets of Washington, D.C., across the swamps of Maryland, and into the forests of Virginia, while the nation, still reeling from the just-ended Civil War, watched in horror and sadness. At the very center of this story is John Wilkes Booth, America's notorious villain. A Confederate sympathizer and a member of a celebrated acting family, Booth threw away his fame and wealth for a chance to avenge the South's defeat. For almost two weeks, he confounded the manhunters, slipping away from their every move and denying them the justice they sought. Based on rare archival materials, obscure trial transcripts, and Lincoln's own blood relics, Manhunt is a fully documented work and a fascinating tale of murder, intrigue, and betrayal. A gripping hour-by-hour account told through the eyes of the hunted and the hunters, this is history as you've never read it before.

    Would you know one if you held it in your hand?In Dark Archives, Megan Rosenbloom seeks out the historic and scientific truths behind anthropodermic bibliopegy--the practice of binding books in this most intimate covering. Dozens of such books live on in the world's most famous libraries and museums. Dark Archives exhumes their origins and brings to life the doctors, murderers, innocents, and indigents whose lives are sewn together in this disquieting collection. Along the way, Rosenbloom tells the story of how her team of scientists, curators, and librarians test rumored anthropodermic books, untangling the myths around their creation and reckoning with the ethics of their custodianship.A librarian and journalist, Rosenbloom is a member of The Order of the Good Death and a cofounder of their Death Salon, a community that encourages conversations, scholarship, and art about mortality and mourning. In Dark Archives--captivating and macabre in all the right ways--she has crafted a narrative that is equal parts detective work, academic intrigue, history, and medical curiosity: a book as rare and thrilling as its subject.

    Early in that fateful year, a second American revolution unfolded, inspiring a new generation to reject their parents’ faith in compromise and appeasement, to do the unthinkable in the name of an ideal. It set Abraham Lincoln on the path to greatness and millions of slaves on the road to freedom.The book introduces us to a heretofore little-known cast of Civil War heroes—among them an acrobatic militia colonel, an explorer’s wife, an idealistic band of German immigrants, a regiment of New York City firemen, a community of Virginia slaves, and a young college professor who would one day become president. Adam Goodheart takes us from the corridors of the White House to the slums of Manhattan, from the mouth of the Chesapeake to the deserts of Nevada, from Boston Common to Alcatraz Island, vividly evoking the Union at this moment of ultimate crisis and decision.