It intersects with Darwin’s theory of evolution, and collides with the horrors of Nazi eugenics in the 1940s. The gene transforms post-war biology. It reorganizes our understanding of sexuality, temperament, choice and free will. This is a story driven by human ingenuity and obsessive minds – from Charles Darwin and Gregor Mendel to Francis Crick, James Watson and Rosalind Franklin, and the thousands of scientists still working to understand the code of codes.This is an epic, moving history of a scientific idea coming to life, by the author of The Emperor of All Maladies. But woven through The Gene, like a red line, is also an intimate history – the story of Mukherjee’s own family and its recurring pattern of mental illness, reminding us that genetics is vitally relevant to everyday lives. These concerns reverberate even more urgently today as we learn to “read” and “write” the human genome – unleashing the potential to change the fates and identities of our children.Majestic in its ambition, and unflinching in its honesty, The Gene gives us a definitive account of the fundamental unit of heredity – and a vision of both humanity’s past and future.

    But things didn't turn out that way. For a start, we turned out to have far fewer genes than originally thought - just over 20,000, the same sort of number as a fruit fly or worm. What's more, the proportionof DNA consisting of genes coding for proteins was a mere 2%. So, was the rest of the genome accumulated 'junk'?Things have changed since those early heady days of the Human Genome Project. But the emerging picture is if anything far more exciting. In this book, John Parrington explains the key features that are coming to light - some, such as the results of the international ENCODE programme, still much debated and controversial in their scope. He gives an outline of the deeper genome, involving layers of regulatory elements controlling and coordinating the switching on and off of genes; the impact ofits 3D geometry; the discovery of a variety of new RNAs playing critical roles; the epigenetic changes influenced by the environment and life experiences that can make identical twins different and be passed on to the next generation; and the clues coming out of comparisons with the genomes ofNeanderthals as well as that of chimps about the development our species. We are learning more about ourselves, and about the genetic aspects of many diseases. But in its complexity, flexibility, and ability to respond to environmental cues, the human genome is proving to be far more subtle than we ever imagined.

    . . and then broke? How would you survive? Could you improve on humanity's original timeline? And how hard would it be to domesticate a giant wombat? With this book as your guide, you'll survive--and thrive--in any period in Earth's history. Bestselling author and time-travel enthusiast Ryan North shows you how to invent all the modern conveniences we take for granted--from first principles. This illustrated manual contains all the science, engineering, art, philosophy, facts, and figures required for even the most clueless time traveler to build a civilization from the ground up. Deeply researched, irreverent, and significantly more fun than being eaten by a saber-toothed tiger, How to Invent Everything will make you smarter, more competent, and completely prepared to become the most important and influential person ever.

    No one seemed able to agree on a cause. (Dark matter? Tensor–vector–scalar gravity? Collisions with gravitons?) What did seem clear to those who became obsessed with it was that the Pioneer Anomaly had the potential to upend Einstein and Newton—to change everything we know about the universe.With riveting prose and the precision of an expert, Konstantin Kakaes gives us a scientific police procedural, tracking the steps of those who sought to unravel this high-stakes enigma. His thrilling account draws on extensive interviews and archival research, following the story from the Anomaly’s initial discovery, through decades of tireless investigation, to its ultimate conclusion. “The Pioneer Detectives” is a definitive account not just of the Pioneer Anomaly but of how scientific knowledge gets made and unmade, with scientists sometimes putting their livelihoods on the line in pursuit of cosmic truth. Perfect for fans of John McPhee, Thomas Kuhn, and Ed McBain, this is also an immensely enjoyable story accessible to anyone who loves brilliant, fascinating long-form journalism.* * * ABOUT THE AUTHOR: Konstantin Kakaes is a Bernard L. Schwartz fellow at the New America Foundation, writing about science and technology, and is the former Mexico City bureau chief for The Economist. His work has been published in The Wall Street Journal, Foreign Policy, and The Washington Post and appears frequently in Slate. Before becoming a journalist, he studied physics at Harvard University.

    As part of the healing process, she decided to use DNA research to learn more about herself, her family, and the interconnectedness of society. She went deep in search of her genealogy, having her DNA sequenced and tested, and effectively becoming an experimental subject. Remarkably, she was able to trace the path of her ancestors through recorded history and into prehistory. Through the course of her research, she met dozens of scientists working in genetic research. The narrative travels the length and breadth of Europe, from the Neanderthals of central Germany to the Cro-Magnon in France. Bojs visited the ancient caves, realizing that her direct ancestors must have been living in the area when the cave art was painted. A second DNA analysis later revealed she has Sami (i.e. Lapp) genetic material in her genome, and there were further revelations about her hunter-gatherer, Bronze-Age, and Iron-Age relatives, including the Vikings. This fresh, first-person exploration of genes and genetics goes well beyond personal genealogy and reveals much about the shared history of European peoples.

    Lewis Dartnell considers some of the fascinating questions facing researchers today. Could life exist anywhere else in the universe? What might aliens really look like? Dartnell explains why Earth is uniquely suited for life and reveals our profound connection to the cosmos.

    This idea is considered a foundation of modern physics, but what if it is wrong? Theoretical physicist Magueijo presents the idea that light traveled faster in the early universe than it does today. The varying speed of light theory solves some of the most intractable problems in cosmology, and could have major implications for the study of physics.

    Dozens of examples in innumeracy show us how it affects not only personal economics and travel plans, but explains mis-chosen mates, inappropriate drug-testing, and the allure of pseudo-science.

    Beginning near the speed of light and proceeding to explorations of space-time and curved spaces, "Introducing Relativity" plots a visually accessible course through the thought experiments that have given shape to contemporary physics. Scientists from Newton to Hawking add their unique contributions to this story, as we encounter Einstein's astounding vision of gravity as the curvature of space-time and arrive at the breathtakingly beautiful field equations. Einstein's legacy is reviewed in the most advanced frontiers of physics today - black holes, gravitational waves, the accelerating universe and string theory. This is a superlative, fascinating graphic account of Einstein's strange world and how his legacy has been built upon since.

    Featuring all-new 3D models built using data gathered by NASA and the European Space Agency, The Planets is an awe-inspiring journey through the Solar System, from Earth to Mars and beyond.Viewed layer by layer, planets and other objects in the Solar System are taken out of the night sky and presented on a white background, revealing every detail of their surface and internal anatomy in astonishing detail.Looking at planets, the Sun, hundreds of moons and thousands of asteroids and comets, The Planets includes timelines that chronicle all major Space missions, right up to the latest Mars rovers, and infographics that present fascinating facts about all planets and the Solar System in a fresh new way.

    Coated in red dust, the terrain is bewilderingly empty. And yet multiple spacecraft are circling Mars, sweeping over Terra Sabaea, Syrtis Major, the dunes of Elysium, and Mare Sirenum—on the brink, perhaps, of a staggering find, one that would inspire humankind as much as any discovery in the history of modern science.In this beautifully observed, deeply personal book, Georgetown scientist Sarah Stewart Johnson tells the story of how she and other researchers have scoured Mars for signs of life, transforming the planet from a distant point of light into a world of its own.Johnson’s fascination with Mars began as a child in Kentucky, turning over rocks with her father and looking at planets in the night sky. She now conducts fieldwork in some of Earth’s most hostile environments, such as the Dry Valleys of Antarctica and the salt flats of Western Australia, developing methods for detecting life on other worlds. Here, with poetic precision, she interlaces her own personal journey—as a female scientist and a mother—with tales of other seekers, from Percival Lowell, who was convinced that a utopian society existed on Mars, to Audouin Dollfus, who tried to carry out astronomical observations from a stratospheric balloon. In the process, she shows how the story of Mars is also a story about Earth: This other world has been our mirror, our foil, a telltale reflection of our own anxieties and yearnings.Empathetic and evocative, The Sirens of Mars offers an unlikely natural history of a place where no human has ever set foot, while providing a vivid portrait of our quest to defy our isolation in the cosmos.

    Charles Darwin played a crucial part in turning heredity into a scientific question, and yet he failed spectacularly to answer it. The birth of genetics in the early 1900s seemed to do precisely that. Gradually, people translated their old notions about heredity into a language of genes. As the technology for studying genes became cheaper, millions of people ordered genetic tests to link themselves to missing parents, to distant ancestors, to ethnic identities. . . .But, Zimmer writes, "Each of us carries an amalgam of fragments of DNA, stitched together from some of our many ancestors. Each piece has its own ancestry, traveling a different path back through human history. A particular fragment may sometimes be cause for worry, but most of our DNA influences who we are--our appearance, our height, our penchants--in inconceivably subtle ways." Heredity isn't just about genes that pass from parent to child. Heredity continues within our own bodies, as a single cell gives rise to trillions of cells that make up our bodies. We say we inherit genes from our ancestors--using a word that once referred to kingdoms and estates--but we inherit other things that matter as much or more to our lives, from microbes to technologies we use to make life more comfortable. We need a new definition of what heredity is and, through Carl Zimmer's lucid exposition and storytelling, this resounding tour de force delivers it. Weaving historical and current scientific research, his own experience with his two daughters, and the kind of original reporting expected of one of the world's best science journalists, Zimmer ultimately unpacks urgent bioethical quandaries arising from new biomedical technologies, but also long-standing presumptions about who we really are and what we can pass on to future generations.

    Around 100 crystal-clear articles explore landmark novels, short stories, plays, and poetry that reinvented the art of writing in their time, whether Ancient Greece, post-classical Europe, or modern-day Korea.As part of DK's award-winning Big Ideas Simply Explained series, The Literature Book uses infographics and images to explain key ideas and themes. Biographies of important authors offer insight into their lives and other writings, and a section on Further Reading details more than 150 additional works to explore.Discover masterpieces from the world's greatest authors, and explore the context, creative history, and literary traditions that influenced each major work of fiction with The Literature Book.Series Overview: Big Ideas Simply Explained series uses creative design and innovative graphics, along with straightforward and engaging writing, to make complex subjects easier to understand. These award-winning books provide just the information needed for students, families, or anyone interested in concise, thought-provoking refreshers on a single subject.

    He went on to become a twentieth-century icon-a man whose name and face are synonymous with "genius." Now, at last, ordinary readers can explore Einstein's life and work in this new For Dummies guide. Physicist Carlos Calle chronicles Einstein's career and explains his work-including the theories of special and general relativity-in language that anyone can understand. He shows how Einstein's discoveries affected everything from the development of the atom bomb to the theory of quantum mechanics. He sheds light on Einstein's personal life and beliefs, including his views on religion and politics. And he shows how Einstein's work continues to affect our world today, from nuclear power to space travel to artificial intelligence.

    Comparing gene sequences, examining atomic structures of proteins, and looking into the geochemistry of rocks have helped explain evolution in more detail than ever before. Nick Lane expertly reconstructs the history of life by describing the ten greatest inventions of evolution (including DNA, photosynthesis, sex, and sight), based on their historical impact, role in organisms today, and relevance to current controversies. Who would have guessed that eyes started off as light-sensitive spots used to calibrate photosynthesis in algae? Or that DNA’s building blocks form spontaneously in hydrothermal vents? Lane gives a gripping, lucid account of nature’s ingenuity, and the result is a work of essential reading for anyone who has ever pondered or questioned the science underlying evolution’s greatest gifts to man.