It has been inspired by the scientific ferment that swept through Britain at the end of the 18th century, and which Holmes now radically redefines as 'the revolution of Romantic Science'.

    But the president insisted there was nothing to worry about.Fortunately, we are still a nation of skeptics. Fortunately, there are those among us who study pandemics and are willing to look unflinchingly at worst-case scenarios. Michael Lewis’s taut and brilliant nonfiction thriller pits a band of medical visionaries against the wall of ignorance that was the official response of the Trump administration to the outbreak of COVID-19.The characters you will meet in these pages are as fascinating as they are unexpected. A thirteen-year-old girl’s science project on transmission of an airborne pathogen develops into a very grown-up model of disease control. A local public-health officer uses her worm’s-eye view to see what the CDC misses, and reveals great truths about American society. A secret team of dissenting doctors, nicknamed the Wolverines, has everything necessary to fight the pandemic: brilliant backgrounds, world-class labs, prior experience with the pandemic scares of bird flu and swine flu…everything, that is, except official permission to implement their work.Michael Lewis is not shy about calling these people heroes for their refusal to follow directives that they know to be based on misinformation and bad science. Even the internet, as crucial as it is to their exchange of ideas, poses a risk to them. They never know for sure who else might be listening in.

    These “psychosurgeons,” as they called themselves, occupied a gray zone between medical research and medical practice, and ended up subjecting untold numbers of people to the types of surgical experiments once limited to chimpanzees.The most important test subject to emerge from this largely untold chapter in American history was a twenty-seven-year-old factory worker named Henry Molaison. In 1953, Henry—who suffered from severe epilepsy—received a radical new version of the lobotomy, one that targeted the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry left the operating room profoundly amnesic, unable to create new long-term memories. Over the next sixty years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.Luke Dittrich uses the case of Patient H.M. as a starting point for a kaleidoscopic journey, one that moves from the first recorded brain surgeries in ancient Egypt to the cutting-edge laboratories of MIT. He takes readers inside the old asylums and operating theaters where psychosurgeons conducted their human experiments, and behind the scenes of a bitter custody battle over the ownership of the most important brain in the world. Throughout, Dittrich delves into the enduring mysteries of the mind while exposing troubling stories of just how far we’ve gone in our pursuit of knowledge. It is also, at times, a deeply personal journey. Dittrich’s grandfather was the brilliant, morally complex surgeon who operated on Molaison—and thousands of other patients. The author’s investigation into the dark roots of modern memory science ultimately forces him to confront unsettling secrets in his own family history, and to reveal the tragedy that fueled his grandfather’s relentless experimentation—experimentation that would revolutionize our understanding of ourselves.Patient H.M. combines the best of biography, memoir, and science journalism to create a haunting, endlessly fascinating story, one that reveals the wondrous and devastating things that can happen when hubris, ambition, and human imperfection collide.

    While they're at it, they helpfully demystify many complicated things we do know about, from quarks and neutrinos to gravitational waves and exploding black holes. With equal doses of humor and delight, they invite us to see the universe as a vast expanse of mostly uncharted territory that's still ours to explore.This entertaining illustrated science primer is the perfect book for anyone who's curious about all the big questions physicists are still trying to answer.

    In Papua New Guinea, a primitive tribe is nearly obliterated by a sickness whose chief symptom is uncontrollable laughter. Across Europe, millions of sheep rub their fleeces raw before collapsing. In England, cows attack their owners in the milking parlors, while in the American West, thousands of deer starve to death in fields full of grass.What these strange conditions–including fatal familial insomnia, kuru, scrapie, and mad cow disease–share is their cause: prions. Prions are ordinary proteins that sometimes go wrong, resulting in neurological illnesses that are always fatal. Even more mysterious and frightening, prions are almost impossible to destroy because they are not alive and have no DNA–and the diseases they bring are now spreading around the world.In The Family That Couldn’t Sleep, essayist and journalist D. T. Max tells the spellbinding story of the prion’s hidden past and deadly future

    But, Alex Bellos says, "math can be inspiring and brilliantly creative. Mathematical thought is one of the great achievements of the human race, and arguably the foundation of all human progress. The world of mathematics is a remarkable place."Bellos has traveled all around the globe and has plunged into history to uncover fascinating stories of mathematical achievement, from the breakthroughs of Euclid, the greatest mathematician of all time, to the creations of the Zen master of origami, one of the hottest areas of mathematical work today. Taking us into the wilds of the Amazon, he tells the story of a tribe there who can count only to five and reports on the latest findings about the math instinct--including the revelation that ants can actually count how many steps they've taken. Journeying to the Bay of Bengal, he interviews a Hindu sage about the brilliant mathematical insights of the Buddha, while in Japan he visits the godfather of Sudoku and introduces the brainteasing delights of mathematical games.Exploring the mysteries of randomness, he explains why it is impossible for our iPods to truly randomly select songs. In probing the many intrigues of that most beloved of numbers, pi, he visits with two brothers so obsessed with the elusive number that they built a supercomputer in their Manhattan apartment to study it. Throughout, the journey is enhanced with a wealth of intriguing illustrations, such as of the clever puzzles known as tangrams and the crochet creation of an American math professor who suddenly realized one day that she could knit a representation of higher dimensional space that no one had been able to visualize. Whether writing about how algebra solved Swedish traffic problems, visiting the Mental Calculation World Cup to disclose the secrets of lightning calculation, or exploring the links between pineapples and beautiful teeth, Bellos is a wonderfully engaging guide who never fails to delight even as he edifies. "Here's Looking at Euclid "is a rare gem that brings the beauty of math to life.

    This was the world of medicine when Thomas Dent Mütter began his trailblazing career as a plastic surgeon in Philadelphia during the middle of the nineteenth century.Although he died at just forty-eight, Mütter was an audacious medical innovator who pioneered the use of ether as anesthesia, the sterilization of surgical tools, and a compassion-based vision for helping the severely deformed, which clashed spectacularly with the sentiments of his time.   Brilliant, outspoken, and brazenly handsome, Mütter was flamboyant in every aspect of his life. He wore pink silk suits to perform surgery, added an umlaut to his last name just because he could, and amassed an immense collection of medical oddities that would later form the basis of Philadelphia’s Mütter Museum. Cristin O’Keefe Aptowicz chronicles how Mütter’s efforts helped establish Philadelphia as a global mecca for medical innovation—despite intense resistance from his numerous rivals.

    Why does music evoke such powerful moods? The answers are at last be- coming clear, thanks to revolutionary neuroscience and the emerging field of evolutionary psychology. Both a cutting-edge study and a tribute to the beauty of music itself, This Is Your Brain on Music unravels a host of mysteries that affect everything from pop culture to our understanding of human nature, including: • Are our musical preferences shaped in utero? • Is there a cutoff point for acquiring new tastes in music? • What do PET scans and MRIs reveal about the brain’s response to music? • Is musical pleasure different from other kinds of pleasure?This Is Your Brain on Music explores cultures in which singing is considered an essential human function, patients who have a rare disorder that prevents them from making sense of music, and scientists studying why two people may not have the same definition of pitch. At every turn, this provocative work unlocks deep secrets about how nature and nurture forge a uniquely human obsession.

    . . full of intellectual treats and tricks, of whimsy and deep scientific philosophy. It is highbrow entertainment at its best, a teasing challenge to all who aspire to think about the universe." — New York Herald TribuneOne of the world's foremost nuclear physicists (celebrated for his theory of radioactive decay, among other accomplishments), George Gamow possessed the unique ability of making the world of science accessible to the general reader.He brings that ability to bear in this delightful expedition through the problems, pleasures, and puzzles of modern science. Among the topics scrutinized with the author's celebrated good humor and pedagogical prowess are the macrocosm and the microcosm, theory of numbers, relativity of space and time, entropy, genes, atomic structure, nuclear fission, and the origin of the solar system.In the pages of this book readers grapple with such crucial matters as whether it is possible to bend space, why a rocket shrinks, the "end of the world problem," excursions into the fourth dimension, and a host of other tantalizing topics for the scientifically curious. Brimming with amusing anecdotes and provocative problems, One Two Three . . . Infinity also includes over 120 delightful pen-and-ink illustrations by the author, adding another dimension of good-natured charm to these wide-ranging explorations.Whatever your level of scientific expertise, chances are you'll derive a great deal of pleasure, stimulation, and information from this unusual and imaginative book. It belongs in the library of anyone curious about the wonders of the scientific universe. "In One Two Three . . . Infinity, as in his other books, George Gamow succeeds where others fail because of his remarkable ability to combine technical accuracy, choice of material, dignity of expression, and readability." — Saturday Review of Literature

    Alexander von Humboldt (1769 – 1859) was an intrepid explorer and the most famous scientist of his age. In North America, his name still graces four counties, thirteen towns, a river, parks, bays, lakes, and mountains. His restless life was packed with adventure and discovery, whether he was climbing the highest volcanoes in the world or racing through anthrax-infected Siberia or translating his research into bestselling publications that changed science and thinking. Among Humboldt's most revolutionary ideas was a radical vision of nature, that it is a complex and interconnected global force that does not exist for the use of humankind alone. Now Andrea Wulf brings the man and his achievements back into focus: his daring expeditions and investigation of wild environments around the world and his discoveries of similarities between climate and vegetation zones on different continents. She also discusses his prediction of human-induced climate change, his remarkable ability to fashion poetic narrative out of scientific observation, and his relationships with iconic figures such as Simón Bolívar and Thomas Jefferson. Wulf examines how Humboldt's writings inspired other naturalists and poets such as Darwin, Wordsworth, and Goethe, and she makes the compelling case that it was Humboldt's influence that led John Muir to his ideas of natural preservation and that shaped Thoreau's Walden.With this brilliantly researched and compellingly written book, Andrea Wulf shows the myriad fundamental ways in which Humboldt created our understanding of the natural world, and she champions a renewed interest in this vital and lost player in environmental history and science.

    Chanda Prescod-Weinstein shares her love for physics, from the Standard Model of Particle Physics and what lies beyond it, to the physics of melanin in skin, to the latest theories of dark matter — all with a new spin informed by history, politics, and the wisdom of Star Trek.One of the leading physicists of her generation, Dr. Chanda Prescod-Weinstein is also one of fewer than one hundred Black American women to earn a PhD from a department of physics. Her vision of the cosmos is vibrant, buoyantly non-traditional, and grounded in Black feminist traditions.Prescod-Weinstein urges us to recognize how science, like most fields, is rife with racism, sexism, and other dehumanizing systems. She lays out a bold new approach to science and society that begins with the belief that we all have a fundamental right to know and love the night sky. The Disordered Cosmos dreams into existence a world that allows everyone to tap into humanity’s wealth of knowledge about the wonders of the universe.

    Scientists are confident that there is alien life across the universe yet we have not moved beyond our perception of 'aliens' as Hollywood stereotypes. The time has come to abandon our fixation on alien monsters and place our expectations on solid scientific footing.Using his own expert understanding of life on Earth and Darwin's theory of evolution - which applies throughout the universe - Cambridge zoologist Dr Arik Kershenbaum explains what alien life must be like: how these creatures will move, socialise and communicate.For example, by observing fishes whose electrical pulses indicate social status, we can see that other planets might allow for communication by electricity. As there was evolutionary pressure to wriggle along a sea floor, Earthling animals tend to have left/right symmetry; on planets where creatures evolved mid-air or in soupy tar they might be lacking any symmetry at all.Might there be an alien planet with supersonic animals? Will they scream with fear, act honestly, or have technology? Is the universe swarming with robots? Dr Kershenbaum uses cutting-edge science to paint an entertaining and compelling picture of extra-terrestrial life.The Zoologist's Guide to the Galaxy is the story of how life really works, on Earth and in space.***'If you don't want to be surprised by extraterrestrial life, look no further than this lively overview of the laws of evolution that have produced life on earth' - Frans de Waal, author of Mama's Last Hug - Animal Emotions and What They Tell Us about Ourselves'A fun, and thoroughly biological, exploration of possible and impossible alien beings. If you'd love to know what real aliens from other planets might really be like, this is the book for you' - Susan Blackmore, author of Seeing Myself'Surveying the deep-time of evolution on Earth and his own cutting-edge research into animal communication, Kershenbaum provides a fascinating insight into the deepest of questions: what might an alien actually look like'- Lewis Dartnell, author of Origins'Arik Kershenbaum takes us on a joyous voyage of animal diversity and illustrates the singular importance of natural selection in explaining life - here on Earth - and what will likely be discovered throughout the galaxy. A stimulating read!' - Daniel T. Blumstein, Professor of Ecology and Evolutionary Biology, University of California Los Angeles

    For centuries, the power of zero savored of the demonic; once harnessed, it became the most important tool in mathematics. Zero follows this number from its birth as an Eastern philosophical concept to its struggle for acceptance in Europe and its apotheosis as the mystery of the black hole. Today, zero lies at the heart of one of the biggest scientific controversies of all time, the quest for the theory of everything. Elegant, witty, and enlightening, Zero is a compelling look at the strangest number in the universe and one of the greatest paradoxes of human thought.

    S. Ramachandran is at the forefront of his field-so much so that Richard Dawkins dubbed him the "Marco Polo of neuroscience." Now, in a major new work, Ramachandran sets his sights on the mystery of human uniqueness. Taking us to the frontiers of neurology, he reveals what baffling and extreme case studies can teach us about normal brain function and how it evolved. Synesthesia becomes a window into the brain mechanisms that make some of us more creative than others. And autism--for which Ramachandran opens a new direction for treatment--gives us a glimpse of the aspect of being human that we understand least: self-awareness. Ramachandran tackles the most exciting and controversial topics in neurology with a storyteller's eye for compelling case studies and a researcher's flair for new approaches to age-old questions. Tracing the strange links between neurology and behavior, this book unveils a wealth of clues into the deepest mysteries of the human brain.

    According to this false-yet-familiar story, the divisions between men and women are in nature alone and not part of culture. Drawing on evolutionary science, psychology, neuroscience, endocrinology, and philosophy, Testosterone Rex disproves this ingrained myth and calls for a more equal society based on both sexes’ full human potential.