We now understand more about aging—and how to prevent and reverse it—than ever before.In recent years, our understanding of the nature of aging has grown exponentially, and dramatic life extension—even age reversal—has moved from science fiction to real possibility.Dr. Michael Fossel has been in the forefront of aging research for decades and is the author of the definitive textbook on human aging. In The Telomerase Revolution, he takes us on a detailed but highly accessible scientific journey, providing startling insights into the nature of human aging.On first examination, aging appears inevitable and straight-forward. Everything, after all, from mountains and galaxies, to plants and animals, ages, doesn’t it? Not exactly. With deeper consideration, aging turns out to be complex, and surprising questions emerge:Is aging something that happens within our cells or in the organism as a whole?Why do some cells age every time they reproduce, while others can reproduce indefinitely, without signs of aging?How close are we to being able to dramatically extend life-spans and cure age-related diseases such as Alzheimer’s, dementia, and strokes?Instead of the common idea that “we accumulate damage, therefore we age,” the reality is the opposite: our cells age and so we begin to accumulate damage. The latest research shows so-called “ageless” cells contain “telomerase”—an enzyme that maintains telomeres and adds back segments lost during replication. Essentially, it is the telomere that controls how well our cells repair themselves over time.The Telomerase Revolution explains simply how we came to understand the ways aging and age-related diseases work, what we can do about them now, what we will be able to do to cure and prevent these diseases—and why we are now on the brink of a revolution in human medicine.

    Colorful sidebars and numerous photographs highlight key information and provide extra training tips that every owner will appreciate.

    

    bataar bones he was impressed. The enormous skull and teeth betrayed the apex predators close relation to the storied Tyrannosaurus rex, the most famous animal that ever lived. Prokopi's obsession with fossils had begun decades earlier, when he was a Florida boy scouring for shark teeth and Ice Age remnants, and it had continued as he built a thriving business hunting, preparing, and selling specimens to avid collectors and private museums around the world. To scientists' fury and dismay, there was big money to be made in certain corners of the fossil trade. Prokopi didn't consider himself merely a businessman, though. He also thought of himself as a vital part of paleontology--as one of the lesser-known artistic links in bringing prehistoric creatures back to life--and saw nothing wrong with turning a profit in the process. Bone hunting was expensive, risky, controversial work, and he increasingly needed bigger "scores." By the time he acquired a largely complete skeleton of T. bataar and restored it in his workshop, he was highly leveraged and drawing quiet scorn from peers who worried that by bringing such a big, beautiful Mongolian dinosaur to market he would tarnish the entire trade. Presenting the skeleton for sale at a major auction house in New York City, he was relieved to see the bidding start at nearly $1 million---only to fall apart when the president of Mongolia unexpectedly stepped in to question the specimen's origins and demand its return. An international custody battle ensued, shining new light on the black market for dinosaur fossils, the angst of scientists who fear for their field, and the precarious political tensions in post-Communist Mongolia. The Prokopi case, unprecedented in American jurisprudence, continues to reverberate throughout the intersecting worlds of paleontology, museums, art, and geopolitics.

    The most trusted sources in the auto industry have called its Model S the most advanced, safest and best-performing car ever built - and it doesn’t use a drop of gasoline. Tesla has changed the way the public perceives electric vehicles, and inspired the major automakers to revive their own dormant efforts to sell EVs. However, even amidst the avalanche of media coverage that followed the triumph of the Model S, few have grasped the true significance of what is happening. Tesla has redefined the automobile, sparked a new wave of innovation comparable to the internet and mobile computing revolutions, and unleashed forces that will transform not just the auto industry, but every aspect of society. The Tesla story is one part of an ongoing tide of change driven by the use of information technology to eliminate “friction” such as geographic distance, middlemen and outdated regulations. Tesla is simply applying the new order to the auto industry, but the automobile is such a pervasive influence in our lives that redefining how it is designed, built, driven and sold will have sweeping effects in unexpected areas. Just as Tesla built the Model S as an electric vehicle “from the ground up,” it has taken an outsider’s approach to the way it markets its cars. Its direct sales model has drawn legal challenges from entrenched auto dealers, who fear that their outdated business model will be destroyed. Its systems approach to the software and electronics in its cars has highlighted how far behind the technological times the major automakers are. It’s easy to see why readers find Tesla irresistible. CEO Elon Musk is a superstar entrepreneur, a “nauseatingly pro-US” immigrant and the leader of two other cutting-edge companies. Tesla dares to challenge the establishment behemoths and, so far at least, has handily beaten them at their own game. In this history of the 21st century’s most exciting startup, Charles Morris begins with a brief history of EVs and a biography of Tesla’s driving force, Elon Musk. He then details the history of the company, told in the words of the Silicon Valley entrepreneurs who made it happen. There are many fascinating stories here: Martin Eberhard’s realization that there were many like himself, who loved fast cars but wanted to help the environment and bring about the post-oil age; the freewheeling first days, reminiscent of the early internet era; the incredible ingenuity of the team who built the Roadster; Tesla’s near-death experience and miraculous resurrection; the spiteful split between the company’s larger-than-life leaders; the gloves-off battles with hostile media such as Top Gear and the New York Times; and the media’s ironic about-face when the magnificent Model S won the industry’s highest honors, and naysayers became cheerleaders overnight. And the story is just beginning: Tesla has breathtakingly ambitious plans for the future.This book was updated May 1, 2015 to include the latest on the Gigafactory and the D package.

    

    With the style and wit that have made Capstick the acclaimed heir to Hemingway and Ruark, he again delivers a masterpiece of true adventure that is scarier and more suspenseful than any fiction--because it is true!

    For The Best of Gerald Durrell she has chosen evocative, quirky, engaging and humorous pieces to give a wonderful picture of how his extraordinary life unfolded. Starting with his early naturalist days and the rapid development of his passion for animals, this anthology includes writings of his collecting trips to such places as Cameroon, Argentina and Madagascar, his growing concern about the nature of zoos, the emergence of his conservation plans, and the realization of his lifelong dream, a zoo of his own, and how it became a model for the future.

    

    Young Lucille Marker experiences survival during the Depression, one of the worst dust storms in history, and finally the disintegration of the close-knit community in which she grows up.Readers who like the books of Laura Ingalls Wilder or Willa Cather will enjoy Farm Girl. Set in the locale of Willa Cather's Nebraska novels, it includes a chapter about the Marker/Cather family connections. Richly photographed throughout with over sixty authentic photos documenting the people and places of the story, this historical, easy-to-read small book is suitable for use in the classroom.

    Follow one veterinarian's story through the course of her career and experience the dramas, the traumas and the comedies that regularly take place in a veterinary emergency room. Become privy to some of the authors most humorous, shocking and hackle-raising encounters with animals and overhear some of the more memorable conversations that she has had with owners throughout her years of practice. Follow her through her foreign travels and learn how modern veterinary medicine far exceeds the medical care that is available in these third world countries.Bite Me gives a rare insider's view of the frustrations, the joys and the heartbreak that veterinarians experience on a daily basis and exposes the reasons why the veterinary profession is currently facing some dire and frightening challenges. From page to page you will find yourself laughing, crying, angry, shocked, laughing again, and then eager to know more.Bite Me is a must-read for any pet owner, any person aspiring to be a veterinarian, any veterinary student, and any person who has an interest in the welfare of both animals and people.

    As a young ornithology instructor at the Hog Island Audubon Camp, Dr. Stephen W. Kress learned that puffins had nested on nearby islands until extirpated by hunters in the late 1800s. To right this environmental wrong, he resolved to bring puffins back to one such island—Eastern Egg Rock. Yet bringing the plan to reality meant convincing skeptics, finding resources, and inventing restoration methods at a time when many believed in “letting nature take its course.” Today, Project Puffin has restored more than 1,000 puffin pairs to three Maine islands. But even more exciting, techniques developed during the project have helped to restore rare and endangered seabirds worldwide. Further, reestablished puffins now serve as a window into the effects of global warming. The success of Dr. Kress’s project offers hope that people can restore lost wildlife populations and the habitats that support them. The need for such inspiration has never been greater.

    Within hours, hundreds are dead. What happened? The true story of one of history's most tragic and shocking disasters...in which aviation, terrorism, a sudden change in the weather and plain old bad luck made for a ruinous mix. This gripping novella length work unravels the mind-boggling facts of this catastrophe as a compelling, action-packed and haunting tale of the human condition that will have you turning the pages to the very end.

    Someone [the murderer?] had covered him with a small strip of carpet.Nearby, in a ditch,lay Mrs Chandler - her face and torso bafflingly blanketed in beer cartons.The discovery made international headlines. It swiftly emerged that Dr Bogle, a brilliant specialist in solid state physics, had recently accepted a research post in Washington – and had been preparing to fly there, with his wife and children. Mrs Chandler, who’d worked as a nurse before her marriage, had been at the same New Year’s party with Gilbert Bogle the evening before. They had left separately.Scientists found that the pair had died of acute heart failure – but they could suggest no cause. There were no signs of violence: no smothering or strangulation; no hypodermic marks; no evidence, in the body tissues, of poisons, or radioactive substances of any kind.From the morning the bodies were found, the Bogle-Chandler conundrum would perplex the law’s keenest forensic minds...

    This shocking and groundbreaking report on the trafficking and inhumane treatment of rare and exotic animals exposes a whole network of people and institutions more interested in profit than in animal welfarefrom zoos and wildlife parks to exotic meat dealers and Amish farmers..