He shows how oxygen underpins the origin of biological complexity, the birth of photosynthesis, the sudden evolution of animals, the need for two sexes, the accelerated aging of cloned animals like Dolly the sheep, and the surprisingly long lives of bats and birds. Drawing on this grand evolutionary canvas, Oxygen offers fresh perspectives on our own lives and deaths, explaining modern killer diseases, why we age, and what we can do about it. Advancing revelatory new ideas, following chains of evidence, the book ranges through many disciplines, from environmental sciences to molecular medicine. The result is a captivating vision of contemporary science and a humane synthesis of our place in nature. This remarkable book will redefine the way we think about the world.

    They began their harrowing journey on bicycles, pedaling to Southern France with children's book manuscripts among their few possessions.Louise Borden combed primary resources, including Hans Rey's pocket diaries, to tell this dramatic true story. Archival materials introduce readers to the world of Hans and Margret Rey while Allan Drummond dramatically and colorfully illustrates their wartime trek to a new home.Follow the Rey's amazing story in this unique large format book that resembles a travel journal and includes full-color illustrations, original photos, actual ticket stubs and more. A perfect book for Curious George fans of all ages.

    But her indomitable will and the help of a devoted teacher empower Helen to triumph over incredible adversity. This amazing true story is finally brought to the beginner reader level.

    Desperate for work, she'd taken on a seemingly impossible job -- teaching a child who was deaf, blind, and as ferocious as any wild animal. But Helen Keller needed more than a teacher. She needed someone daring enough to work a miracle. And if anyone was a match for Helen, it was the girl they used to call Miss Spitfire. For Annie, reaching Helen's mind meant losing teeth as raging fists flew. It meant standing up when everyone else had given up. It meant shedding tears at the frustrations and at the triumphs. By telling this inspiring story from Annie Sullivan's point of view, Sarah Miller's debut novel brings an amazing figure to sharp new life. Annie's past, her brazen determination, and her connection to the girl who would call her Teacher have never been clearer.

    But you'll want to read it most for Karen's own words: 'I can walk, I can talk. I can read. I can write. I can do anything."- The New York Times Yes, these are Karen's own words. The words of a small, pig-tailed, freckle-faced child. Yet, no truer words were ever spoken, for Karen had just lived a miracle. "Extraordinary is the word to be used first, last, and repeatedly about this book. Anyone who meets Karen, even on paper, will postpone resigning from the human race." The Saturday Review.

    But sometimes we don't know what to say or do and don't feel comfortable asking. With sensitive insights and thoughtful anecdotes, Help Me Live provides a personal yet thoroughly researched account of words and actions that are most helpful.

    As a result, antibiotic resistance now ranks among the gravest medical problems of modern times. Good Germs, Bad Germs addresses not only this issue but also what has become known as the "hygiene hypothesis"-- an argument that links the over-sanitation of modern life to now-epidemic increases in immune and other disorders. In telling the story of what went terribly wrong in our war on germs, Jessica Snyder Sachs explores our emerging understanding of the symbiotic relationship between the human body and its resident microbes--which outnumber its human cells by a factor of nine to one! The book also offers a hopeful look into a future in which antibiotics will be designed and used more wisely, and beyond that, to a day when we may replace antibacterial drugs and cleansers with bacterial ones--each custom-designed for maximum health benefits.

    Both were brilliant students who attended college--one at Princeton, the other at Columbia--and studied law. Both were young staff officers under General George Washington, and both became war heroes. Politics beckoned them, and each served in the newly formed government of the fledgling nation. Why, then, did these two face each other at dawn in a duel that ended with death for one and opprobrium for the other? Judith St. George's lively biography, told in alternating chapters, brings to life two complex men who played major roles in the formation of the United States.

    Among them was a thirty-year-old doctor named Benjamin Rush. One of the youngest signatories, he was also, among stiff competition, one of the most visionary.A brilliant physician and writer, Rush was known as the "American Hippocrates" for pioneering national healthcare and revolutionizing treatment of mental illness and addiction. Yet medicine is only part of his legacy. Dr. Rush was both a progressive thorn in the side of the American political establishment--a vocal opponent of slavery, capital punishment, and prejudice by race, religion or gender--and close friends with its most prominent leaders. He was the prot�g� of Franklin, the editor of Common Sense, Washington's surgeon general, and the broker of peace between Adams and Jefferson, yet his stubborn convictions more than once threatened his career and his place in the narrative of America's founding.Drawing on a trove of previously unpublished letters and images, the voluminous correspondence between Rush and his better-known counterparts, and his candid and incisive personal writings, New York Times bestselling author and award-winning journalist Stephen Fried resurrects the most significant Founding Father we've never heard of and finally installs Dr. Rush in the pantheon of great American leaders.

    There is Edward Oxford, who shot at Queen Victoria, and Richard Dadd, the brilliant artist and murderer of his father. There is also William Chester Minor, the surgeon from America who killed a stranger in London, and then played a key part in creating the world's finest dictionary. Finally, there is Christiana Edmunds, ‘The Chocolate Cream Poisoner’ and frustrated lover.To these four tales are added new ones, previously unknown. There were five women who went on to become mothers in Broadmoor, giving birth to life when three of them had previously taken it. Then there were the numerous escapes, actual and attempted, as the first doctors tried to assert control over their residents.These are stories from the edge of where true crime meets mental illness. Broadmoor Revealed recounts what life was like for the criminally insane, over one hundred years ago.

    Some women could be teachers or seamstresses, but career options were few. Certainly no women were doctors. But Elizabeth refused to accept the common beliefs that women weren’t smart enough to be doctors, or that they were too weak for such hard work. And she would not take no for an answer. Although she faced much opposition, she worked hard and finally—when she graduated from medical school and went on to have a brilliant career—proved her detractors wrong. This inspiring story of the first female doctor shows how one strong-willed woman opened the doors for all the female doctors to come.

    This warmly told biography of our sixteenth president is enriched by many authentic but seldom told anecdotes and complemented by bold color illustrations that capture the spirit of Lincoln and his era.

    Pursuing the idea that human affection could be understood, studied, even measured, Harlow (1905-1981) arrived at his conclusions by conducting research-sometimes beautiful, sometimes horrible-on the primates in his University of Wisconsin laboratory. Paradoxically, his darkest experiments may have the brightest legacy, for by studying "neglect" and its life-altering consequences, Harlow confirmed love's central role in shaping not only how we feel but also how we think. His work sparked a psychological revolution. The more children experience affection, he discovered, the more curious they become about the world: Love makes people smarter. The biography of both a man and an idea, The Measure of Love is a powerful and at times disturbing narrative that will forever alter our understanding of human relationships.

    Mankind's battle to stay alive and healthy for as long as possible is our oldest, most universal struggle. With his characteristic wit and vastly informed historical scope, Roy Porter examines the war fought between disease and doctors on the battleground of the flesh from ancient times to the present. He explores the many ingenious ways in which we have attempted to overcome disease through the ages: the changing role of doctors, from ancient healers, apothecaries, and blood-letters to today's professionals; the array of drugs, from Ayurvedic remedies to the launch of Viagra; the advances in surgery, from amputations performed by barbers without anesthetic to today's sophisticated transplants; and the transformation of hospitals from Christian places of convalescence to modern medical powerhouses. Cleverly illustrated with historic line drawings, the chronic ailments of humanity provide vivid anecdotes for Porter's enlightening story of medicine's efforts to prevail over a formidable and ever-changing adversary.

    Taro becomes a servant in the household of the noble Lord Akiyama, where he meets Togan, a cook, who teaches Taro and makes his new life bearable. But when Togan is murdered, Taro’s life takes a new direction: He will become a samurai, and redeem the family legacy that has been stolen from him.