In Under the Knife, surgeon Arnold Van de Laar uses his own experience and expertise to tell the witty history of the past, present and future of surgery.From the story of the desperate man from seventeenth-century Amsterdam who grimly cut a stone out of his own bladder to Bob Marley's deadly toe, Under the Knife offers all kinds of fascinating and unforgettable insights into medicine and history via the operating theatre.What happens during an operation? How does the human body respond to being attacked by a knife, a bacterium, a cancer cell or a bullet? And, as medical advances continuously push the boundaries of what medicine can cure, what are the limits of surgery?From the dark centuries of bloodletting and of amputations without anaesthetic to today's sterile, high-tech operating theatres, Under the Knife is both a rich cultural history, and a modern anatomy class for us all.

    Through a series of disastrous decisions, the state government had switched the city’s water to a source that corroded Flint’s aging lead pipes. Complaints about the foul-smelling water were dismissed: the residents of Flint—a largely poor African American city of about 100,000 people—were not seen as credible, even in matters of their own lives.It took 18 months of activism and a band of dogged outsiders to force the state to admit that the water was poisonous. But this was only after 12 people died and Flint's children suffered irreparable harm. The long battle for accountability and a humane response to this man-made disaster have only just begun.In the first full-length account of this epic failure, The Poisoned City recounts the gripping story of Flint’s poisoned water through the people who caused it, suffered from it, and exposed it. It is a chronicle of one town, but could also be about any American city, all made precarious by the neglect of infrastructure and the erosion of democratic decision-making. Cities like Flint are set up to fail—and for the people who live and work in them, the consequences may be mortal.A 2019 Library of Michigan Notable Books

    Arthur Allen reveals a history of vaccination that is both illuminated with hope and shrouded by controversy - covering Jenner's discovery to Pasteur's vaccines for rabies and cholera, to those that safeguarded the children of the 20th century.

    We are now all too aware of how it is applied, but we know far less about how the idea came to be--and where it may yet go.Until Proven Safe tracks the idea of quarantine around the globe, through time and space, chasing the story from the lazarettos and quarantine islands of Venice--built before communicable diseases were really understood--to the hallways of the CDC, NASA, and the cutting-edge labs and conference rooms where the future technology of quarantine is being developed. The result is a tour of an idea that could not be more urgent or relevant, a book full of stories, people, and insights that is as compelling as it is definitive.

    Behind that groundbreaking thought experiment was his hope that we would be inspired to find a way to add humans back to this vision of a restored, healthy planet-only in harmony, not mortal combat, with the rest of nature.But with a million more of us every 4 1/2 days on a planet that’s not getting any bigger, and with our exhaust overheating the atmosphere and altering the chemistry of the oceans, prospects for a sustainable human future seem ever more in doubt. For this long awaited follow-up book, Weisman traveled to more than 20 countries to ask what experts agreed were probably the most important questions on Earth — and also the hardest: How many humans can the planet hold without capsizing? How robust must the Earth’s ecosystem be to assure our continued existence? Can we know which other species are essential to our survival? And, how might we actually arrive at a stable, optimum population, and design an economy to allow genuine prosperity without endless growth?Weisman visits an extraordinary range of the world’s cultures, religions, nationalities, tribes, and political systems to learn what in their beliefs, histories, liturgies, or current circumstances might suggest that sometimes it’s in their own best interest to limit their growth. The result is a landmark work of reporting: devastating, urgent, and, ultimately, deeply hopeful.By vividly detailing the burgeoning effects of our cumulative presence, Countdown reveals what may be the fastest, most acceptable, practical, and affordable way of returning our planet and our presence on it to balance. Weisman again shows that he is one of the most provocative journalists at work today, with a book whose message is so compelling that it will change how we see our lives and our destiny.

    But in the modern world, the breast is changing. Breasts are getting bigger, arriving earlier, and attracting newfangled chemicals. Increasingly, the odds are stacked against us in the struggle with breast cancer, even among men. What makes breasts so mercurial—and so vulnerable?In this informative and highly entertaining account, intrepid science reporter Florence Williams sets out to uncover the latest scientific findings from the fields of anthropology, biology, and medicine. Her investigation follows the life cycle of the breast from puberty to pregnancy to menopause, taking her from a plastic surgeon’s office where she learns about the importance of cup size in Texas to the laboratory where she discovers the presence of environmental toxins in her own breast milk. The result is a fascinating exploration of where breasts came from, where they have ended up, and what we can do to save them.

    Kaplan, the bestselling author of Monsoon and Balkan Ghosts, offers a revelatory new prism through which to view global upheavals and to understand what lies ahead for continents and countries around the world.   In The Revenge of Geography, Kaplan builds on the insights, discoveries, and theories of great geographers and geopolitical thinkers of the near and distant past to look back at critical pivots in history and then to look forward at the evolving global scene. Kaplan traces the history of the world’s hot spots by examining their climates, topographies, and proximities to other embattled lands. The Russian steppe’s pitiless climate and limited vegetation bred hard and cruel men bent on destruction, for example, while Nazi geopoliticians distorted geopolitics entirely, calculating that space on the globe used by the British Empire and the Soviet Union could be swallowed by a greater German homeland.   Kaplan then applies the lessons learned to the present crises in Europe, Russia, China, the Indian subcontinent, Turkey, Iran, and the Arab Middle East. The result is a holistic interpretation of the next cycle of conflict throughout Eurasia. Remarkably, the future can be understood in the context of temperature, land allotment, and other physical certainties: China, able to feed only 23 percent of its people from land that is only 7 percent arable, has sought energy, minerals, and metals from such brutal regimes as Burma, Iran, and Zimbabwe, putting it in moral conflict with the United States. Afghanistan’s porous borders will keep it the principal invasion route into India, and a vital rear base for Pakistan, India’s main enemy. Iran will exploit the advantage of being the only country that straddles both energy-producing areas of the Persian Gulf and the Caspian Sea. Finally, Kaplan posits that the United States might rue engaging in far-flung conflicts with Iraq and Afghanistan rather than tending to its direct neighbor Mexico, which is on the verge of becoming a semifailed state due to drug cartel carnage.   A brilliant rebuttal to thinkers who suggest that globalism will trump geography, this indispensable work shows how timeless truths and natural facts can help prevent this century’s looming cataclysms.

    In The Poisoner's Handbook Blum draws from highly original research to track the fascinating, perilous days when a pair of forensic scientists began their trailblazing chemical detective work, fighting to end an era when untraceable poisons offered an easy path to the perfect crime. Drama unfolds case by case as the heroes of The Poisoner's Handbook—chief medical examiner Charles Norris and toxicologist Alexander Gettler—investigate a family mysteriously stricken bald, Barnum and Bailey's Famous Blue Man, factory workers with crumbling bones, a diner serving poisoned pies, and many others. Each case presents a deadly new puzzle and Norris and Gettler work with a creativity that rivals that of the most imaginative murderer, creating revolutionary experiments to tease out even the wiliest compounds from human tissue. Yet in the tricky game of toxins, even science can't always be trusted, as proven when one of Gettler's experiments erroneously sets free a suburban housewife later nicknamed "America's Lucretia Borgia" to continue her nefarious work. From the vantage of Norris and Gettler's laboratory in the infamous Bellevue Hospital it becomes clear that killers aren't the only toxic threat to New Yorkers. Modern life has created a kind of poison playground, and danger lurks around every corner. Automobiles choke the city streets with carbon monoxide; potent compounds, such as morphine, can be found on store shelves in products ranging from pesticides to cosmetics. Prohibition incites a chemist's war between bootleggers and government chemists while in Gotham's crowded speakeasies each round of cocktails becomes a game of Russian roulette. Norris and Gettler triumph over seemingly unbeatable odds to become the pioneers of forensic chemistry and the gatekeepers of justice during a remarkably deadly time. A beguiling concoction that is equal parts true crime, twentieth-century history, and science thriller, The Poisoner's Handbook is a page-turning account of a forgotten New York.

    The threat of the disease kept ships close to home and doomed those vessels that ventured too far from port. The willful ignorance of the royal medical elite, who endorsed ludicrous medical theories based on speculative research while ignoring the life-saving properties of citrus fruit, cost tens of thousands of lives and altered the course of many battles at sea. The cure for scurvy ranks among the greatest of human accomplishments, yet its impact on history has, until now, been largely ignored.From the earliest recorded appearance of the disease in the sixteenth century, to the eighteenth century, where a man had only half a chance of surviving the scourge, to the early nineteenth century, when the British conquered scurvy and successfully blockaded the French and defeated Napoleon, Scurvy is a medical detective story for the ages, the fascinating true story of how James Lind (the surgeon), James Cook (the mariner), and Gilbert Blane (the gentleman) worked separately to eliminate the dreaded affliction.Scurvy is an evocative journey back to the era of wooden ships and sails, when the disease infiltrated every aspect of seafaring life: press gangs "recruit" mariners on the way home from a late night at the pub; a terrible voyage in search of riches ends with a hobbled fleet and half the crew heaved overboard; Cook majestically travels the South Seas but suffers an unimaginable fate. Brimming with tales of ships, sailors, and baffling bureaucracy, Scurvy is a rare mix of compelling history and classic adventure story.

    Lab 257 blows the lid off the stunning true nature and checkered history of Plum Island. It shows that the seemingly bucolic island in the shadow of New York City is a ticking biological time bomb that none of us can safely ignore.Based on declassified government documents, in-depth interviews, and access to Plum Island itself, this is an eye-opening, suspenseful account of a federal government germ laboratory gone terribly wrong. For the first time, Lab 257 takes you deep inside this secret world and presents startling revelations on virus outbreaks, biological meltdowns, infected workers, the periodic flushing of contaminated raw sewage into area waters, and the insidious connections between Plum Island, Lyme disease, and the deadly West Nile virus. The book also probes what's in store for Plum Island's new owner, the Department of Homeland Security, in this age of bioterrorism.Lab 257 is a call to action for those concerned with protecting present and future generations from preventable biological catastrophes.

    They distill more than 20 years of research and first-hand accounts from the most biodiverse ecosystems on Earth into straightforward principles and guidance for confronting our culture of hyper-novelty.For evolutionary biologists Heather Heying and Bret Weinstein, the cause of our woes is clear: the modern world is out of sync with our ancient brains and bodies. We evolved to live in clans, but today most people don't even know their neighbors' names. Differences between the sexes once served a necessary evolutionary purpose, but today many dismiss the concept of biological sex as offensive. The cognitive dissonance spawned by trying to live in a society we're not built for is killing us.

    Sapolsky's storytelling concept is delightful but it also has a powerful intrinsic logic: he starts by looking at the factors that bear on a person's reaction in the precise moment a behavior occurs, and then hops back in time from there, in stages, ultimately ending up at the deep history of our species and its evolutionary legacy.And so the first category of explanation is the neurobiological one. A behavior occurs--whether an example of humans at our best, worst, or somewhere in between. What went on in a person's brain a second before the behavior happened? Then Sapolsky pulls out to a slightly larger field of vision, a little earlier in time: What sight, sound, or smell caused the nervous system to produce that behavior? And then, what hormones acted hours to days earlier to change how responsive that individual is to the stimuli that triggered the nervous system? By now he has increased our field of vision so that we are thinking about neurobiology and the sensory world of our environment and endocrinology in trying to explain what happened.Sapolsky keeps going: How was that behavior influenced by structural changes in the nervous system over the preceding months, by that person's adolescence, childhood, fetal life, and then back to his or her genetic makeup? Finally, he expands the view to encompass factors larger than one individual. How did culture shape that individual's group, what ecological factors millennia old formed that culture? And on and on, back to evolutionary factors millions of years old.The result is one of the most dazzling tours d'horizon of the science of human behavior ever attempted, a majestic synthesis that harvests cutting-edge research across a range of disciplines to provide a subtle and nuanced perspective on why we ultimately do the things we do...for good and for ill. Sapolsky builds on this understanding to wrestle with some of our deepest and thorniest questions relating to tribalism and xenophobia, hierarchy and competition, morality and free will, and war and peace. Wise, humane, often very funny, Behave is a towering achievement, powerfully humanizing, and downright heroic in its own right.

    Guy Leschziner's patients, there is no rest for the weary in mind and body. Insomnia, narcolepsy, night terrors, sleep apnea, and sleepwalking are just a sampling of conditions afflicting sufferers who cannot sleep--and their experiences in trying are the stuff of nightmares. Demoniac hallucinations frighten people into paralysis. Restless legs rock both the sleepless and their sleeping partners with unpredictable and uncontrollable kicking. Out-of-sync circadian rhythms confuse the natural body clock's days and nights.Then there are the extreme cases. A woman in a state of deep sleep who gets dressed, unlocks her car, and drives for several miles before returning to bed. The man who has spent decades cleaning out kitchens while "sleep-eating." The teenager prone to the serious, yet unfortunately nicknamed "Sleeping Beauty Syndrome" stuck in a cycle of excessive unconsciousness, binge eating, and uncharacteristic displays of aggression and hyper-sexuality while awake.With compassionate stories of his patients and their conditions, Dr. Leschziner illustrates the neuroscience behind our sleeping minds, revealing the many biological and psychological factors necessary in getting the rest that will not only maintain our physical and mental health, but improve our cognitive abilities and overall happiness.

    Would you know one if you held it in your hand?In Dark Archives, Megan Rosenbloom seeks out the historic and scientific truths behind anthropodermic bibliopegy--the practice of binding books in this most intimate covering. Dozens of such books live on in the world's most famous libraries and museums. Dark Archives exhumes their origins and brings to life the doctors, murderers, innocents, and indigents whose lives are sewn together in this disquieting collection. Along the way, Rosenbloom tells the story of how her team of scientists, curators, and librarians test rumored anthropodermic books, untangling the myths around their creation and reckoning with the ethics of their custodianship.A librarian and journalist, Rosenbloom is a member of The Order of the Good Death and a cofounder of their Death Salon, a community that encourages conversations, scholarship, and art about mortality and mourning. In Dark Archives--captivating and macabre in all the right ways--she has crafted a narrative that is equal parts detective work, academic intrigue, history, and medical curiosity: a book as rare and thrilling as its subject.

    But for thousands of years, people have done things like this—and things that make radioactive underpants seem downright sensible! In their hit podcast, Sawbones, Sydnee and Justin McElroy breakdown the weird and wonderful way we got to modern healthcare. And some of the terrifying detours along the way.Every week, Dr. Sydnee McElroy and her husband Justin amaze, amuse, and gross out (depending on the week) hundreds of thousands of avid listeners to their podcast, Sawbones. Consistently rated a top podcast on iTunes, with over 15 million total downloads, this rollicking journey through thousands of years of medical mishaps and miracles is not only hilarious but downright educational. While you may never even consider applying  boiled weasel to your forehead (once the height of sophistication when it came to headache cures), you will almost certainly face some questionable medical advice in your everyday life (we’re looking at you, raw water!) and be better able to figure out if this is a miracle cure (it’s not) or a scam. Table of Contents:Part One: The Unnerving The Resurrection Men Fun w Galvanism Weird Weight Loss Miracle Cure: Opium Black Plague Heroes of Misguided Medicine: Pliny the Elder Erectile Dysfunction The Doctor Is In: Listener Questions Answered Don’t Drill a Hole in Your HeadPart Two: The Gross Mummy Medicine The Guthole Bromance The Unkillable Phineas Gage Max Drank Poopy Water Heroes of Misguided Medicine: Robert Liston Golden Showers of Health Miracle Cure-All: Radium Dr. John Romulus Brinkley The Doctor Is In Q&A Just (Four) Humour Me The Camel Dung MiraclePart Three: The Weird The Dancing Plague Bad Medicine: Tobacco for Health The Seasick-Proof Saloon Miracle Cure-All: Vinegar The Doctor Is In Q&A Heroes of Misguided MedicinePart Four: The Awesome The Poison Squad Bad Medicine: Self Experimentation Eat Your Chocolate! Heroes of Misguided Medicine Parrot Fever Miracle Cure-All: Honey The Miraculous Polio Vaccine The Doctor Is In