He was a successful psychologist and writer, with books to his name and bylines in major magazines. But none of that mattered. The impulse to take his own life remained. At times it felt all but inescapable.   Bering survived. And in addition to relief, the fading of his suicidal thoughts brought curiosity. Where had they come from? Would they return? Is the suicidal impulse found in other animals? Or is our vulnerability to suicide a uniquely human evolutionary development? In Suicidal, Bering answers all these questions and more, taking us through the science and psychology of suicide, revealing its cognitive secrets and the subtle tricks our minds play on us when we’re easy emotional prey. Scientific studies, personal stories, and remarkable cross-species comparisons come together to help readers critically analyze their own doomsday thoughts while gaining broad insight into a problem that, tragically, will most likely touch all of us at some point in our lives. But while the subject is certainly a heavy one, Bering’s touch is light. Having been through this himself, he knows that sometimes the most effective response to our darkest moments is a gentle humor, one that, while not denying the seriousness of suffering, at the same time acknowledges our complicated, flawed, and yet precious existence.   Authoritative, accessible, personal, profound—there’s never been a book on suicide like this. It will help you understand yourself and your loved ones, and it will change the way you think about this most vexing of human problems.

    An epic, first-of-its-kind book, entwining leading-edge scientific discovery with the intimate stories of four individual lives, by the Pulitzer Prize–winning New York Times journalist.A terminal cancer patient rises from the grave. A medical marvel defies HIV. Two women with autoimmunity discover their own bodies have turned against them. Matt Richtel's An Elegant Defense uniquely entwines these intimate stories with science’s centuries-long quest to unlock the mysteries of sickness and health, and illuminates the immune system as never before.The immune system is our body’s essential defense network, a guardian vigilantly fighting illness, healing wounds, maintaining order and balance, and keeping us alive. Its legion of microscopic foot soldiers—from T cells to “natural killers”—patrols our body, linked by a nearly instantaneous communications grid. It has been honed by evolution over millennia to face an almost infinite array of threats.For all its astonishing complexity, however, the immune system can be easily compromised by fatigue, stress, toxins, advanced age, and poor nutrition—hallmarks of modern life—and even by excessive hygiene. Paradoxically, it is a fragile wonder weapon that can turn on our own bodies with startling results, leading today to epidemic levels of autoimmune disorders.Richtel effortlessly guides readers on a scientific detective tale winding from the Black Plague to twentieth-century breakthroughs in vaccination and antibiotics, to the cutting-edge laboratories that are revolutionizing immunology—perhaps the most extraordinary and consequential medical story of our time. The foundation that Richtel builds makes accessible revelations about cancer immunotherapy, the microbiome, and autoimmune treatments that are changing millions of lives. An Elegant Defense also captures in vivid detail how these powerful therapies, along with our behavior and environment, interact with the immune system, often for the good but always on a razor’s edge that can throw this remarkable system out of balance.Drawing on his groundbreaking reporting for the New York Times and based on extensive new interviews with dozens of world-renowned scientists, Matt Richtel has produced a landmark book, equally an investigation into the deepest riddles of survival and a profoundly human tale that is movingly brought to life through the eyes of his four main characters, each of whom illuminates an essential facet of our “elegant defense.”

    We see it, touch it, and live in it every day. It is a habitat for a mesmerizingly complex world of micro-organisms and physical functions that are vital to our health and our survival. It is also a waste removal plant, a warning system for underlying disease and a dynamic immune barrier to infection. One of the first things people see about us, skin is crucial to our sense of identity, providing us with social significance and psychological meaning. And yet our skin and the fascinating way it functions is largely unknown to us. In prose as lucid as his research underlying it is rigorous, blending in memorable stories from the past and from his own medical experience, Monty Lyman has written a revelatory book exploring our outer surface that will surprise and enlighten in equal measure. Through the lenses of science, sociology, and history--on topics as diverse as the mechanics and magic of touch (how much goes on in the simple act of taking keys out of a pocket and unlocking a door is astounding), the close connection between the skin and the gut, what happens instantly when one gets a paper cut, and how a midnight snack can lead to sunburn--Lyman leads us on a journey across our most underrated and unexplored organ and reveals how our skin is far stranger, more wondrous, and more complex than we have ever imagined.

    He was also a memoirist who wrote with honesty and humor about the remarkable and strange encounters and experiences that shaped him (Uncle Tungsten, On the Move, Gratitude). Sacks, an Oxford-educated polymath, had a deep familiarity not only with literature and medicine but with botany, animal anatomy, chemistry, the history of science, philosophy, and psychology. The River of Consciousness is one of two books Sacks was working on up to his death, and it reveals his ability to make unexpected connections, his sheer joy in knowledge, and his unceasing, timeless project to understand what makes us human.

    Bell ruling made government sterilization of "undesirable" citizens the law of the land. New York Times bestselling author Adam Cohen tells the story in Imbeciles of one of the darkest moments in the American legal tradition: the Supreme Court's decision to champion eugenic sterilization for the greater good of the country. In 1927, when the nation was caught up in eugenic fervor, the justices allowed Virginia to sterilize Carrie Buck, a perfectly normal young woman, for being an "imbecile." It is a story with many villains, from the superintendent of the Dickensian Virginia Colony for Epileptics and Feebleminded who chose Carrie for sterilization to the former Missouri agriculture professor and Nazi sympathizer who was the nation's leading advocate for eugenic sterilization. But the most troubling actors of all were the eight Supreme Court justices who were in the majority--including William Howard Taft, the former president; Louis Brandeis, the legendary progressive; and Oliver Wendell Holmes, Jr., America's most esteemed justice, who wrote the decision urging the nation to embark on a program of mass eugenic sterilization

    Coffee. Sunscreen. Vapes. George Zaidan reveals what will kill you, what won't, and why--explained with high-octane hilarity, hysterical hijinks, and other things that don't begin with the letter H. INGREDIENTS offers the perspective of a chemist on the stuff we eat, drink, inhale, and smear on ourselves. Apart from the burning question of whether you should eat that Cheeto, Zaidan explores a range of topics. Here's a helpful guide:Stuff in this book: - How bad is processed food? How sure are we?- Is sunscreen safe? Should you use it?- Is coffee good or bad for you?- What's your disease horoscope?- What is that public pool smell made of?- What happens when you overdose on fentanyl in the sun?- What do cassava plants and Soviet spies have in common?- When will you die?Stuff in other books: - Your carbon footprint- Food sustainability- GMOs- CEO pay- Science funding- Politics- Football- Baseball- Any kind of ball reallyZaidan, an MIT-trained chemist who cohosted CNBC's hit Make Me a Millionaire Inventor and wrote and voiced several TED-Ed viral videos, makes chemistry more fun than Hogwarts as he reveals exactly what science can (and can't) tell us about the packaged ingredients sold to us every day. Sugar, spinach, formaldehyde, cyanide, the ingredients of life and death, and how we know if something is good or bad for us--as well as the genius of aphids and their butts--are all discussed in exquisite detail at breakneck speed.

    Drawing on evidence from archaeology, history, cognitive neuroscience, psychopharmacology, social psychology, literature, and genetics, Slingerland shows that our taste for chemical intoxicants is not an evolutionary mistake, as we are so often told. In fact, intoxication helps solve a number of distinctively human challenges: enhancing creativity, alleviating stress, building trust, and pulling off the miracle of getting fiercely tribal primates to cooperate with strangers. Our desire to get drunk, along with the individual and social benefits provided by drunkenness, played a crucial role in sparking the rise of the first large-scale societies. We would not have civilization without intoxication. From marauding Vikings and bacchanalian orgies to sex-starved fruit flies, blind cave fish, and problem-solving crows, Drunk is packed with fascinating case studies and engaging science, as well as practical takeaways for individuals and communities. The result is a captivating and long overdue investigation into humanity's oldest indulgence—one that explains not only why we want to get drunk, but also how it might actually be good for us to tie one on now and then.

    Between 1900 and 1907, she infected twenty-two New Yorkers with typhoid fever through her puddings and cakes; one of them died. Tracked down through epidemiological detective work, she was finally apprehended as she hid behind a barricade of trashcans. To protect the public's health, authorities isolated her on Manhattan's North Brother Island, where she died some thirty years later.This book tells the remarkable story of Mary Mallon--the real Typhoid Mary. Combining social history with biography, historian Judith Leavitt re-creates early-twentieth-century New York City, a world of strict class divisions and prejudice against immigrants and women. Leavitt engages the reader with the excitement of the early days of microbiology and brings to life the conflicting perspectives of journalists, public health officials, the law, and Mary Mallon herself.Leavitt's readable account illuminates dilemmas that continue to haunt us. To what degree are we willing to sacrifice individual liberty to protect the public's health? How far should we go in the age of AIDS, drug-resistant tuberculosis, and other diseases? For anyone who is concerned about the threats and quandaries posed by new epidemics, Typhoid Mary is a vivid reminder of the human side of disease and disease control.

    Then a policeman came along. Thinking he had another sick drunk on his hands, the policeman bent over the old man. He was quite surprised to see that the old man's nose, lips, ears and fingers were sky blue...By that evening eleven blue men were in the hospital, all in a state of shock. Doctors were baffled. And so investigators from the Department of Health, assuming the guise of detectives, were sent out to track down the unknown assailant...

    She focuses on a different danger in each chapter-from the looming risk of lethal influenza to in-depth information on the public health perils posed by bioterrorism. With a novelist's descriptive eye and a thriller writer's sense of tension, she warns us that the most ceaselessly creative bioterrorist is still Mother Nature, whose microbial operatives are all around us, ready to pounce when conditions are right.

    Steven Hatch first came to Liberia in November 2013, to work at a hospital in Monrovia. Six months later, several of the physicians Dr. Hatch had mentored and served with were dead or barely clinging to life, and Ebola had become a world health emergency. Hundreds of victims perished each week; whole families were destroyed in a matter of days; so many died so quickly that the culturally taboo practice of cremation had to be instituted to dispose of the bodies. With little help from the international community and a population ravaged by disease and fear, the war-torn African nation was simply unprepared to deal with the catastrophe.A physician’s memoir about the ravages of a terrible disease and the small hospital that fought to contain it, Inferno is also an explanation of the science and biology of Ebola: how it is transmitted and spreads with such ferocity. And as Dr. Hatch notes, while Ebola is temporarily under control, it will inevitably re-emerge—as will other plagues, notably the Zika virus, which the World Health Organization has declared a public health emergency. Inferno is a glimpse into the white-hot center of a crisis that will come again.

     Few people know much about stem cell research beyond the ethical questions raised by using embryos. But in the last decade, stem cell research has made huge advances toward eliminating some of our most intractable diseases. Now this sweeping and accessible book introduces us to this cutting-edge science that will revolutionize medicine and change the way we think about and treat disease. Alice Park takes us from stem cell's controversial beginnings to the recent electrifying promise of being able to create the versatile cells without using embryos at all. She shows us how stem cells give researchers an unprecedented ability to study disease while giving patients the promise of replacing diseased cells with healthy new ones. And she profiles the scientists and leaders-many with their own compelling stories-who have fueled the quest and will continue to shape the field in years to come.

    Yet this is the first book to tell the story of rain. Cynthia Barnett's  Rain begins four billion years ago with the torrents that filled the oceans, and builds to the storms of climate change. It weaves together science—the true shape of a raindrop, the mysteries of frog and fish rains—with the human story of our ambition to control rain, from ancient rain dances to the 2,203 miles of levees that attempt to straitjacket the Mississippi River. It offers a glimpse of our "founding forecaster," Thomas Jefferson, who measured every drizzle long before modern meteorology. Two centuries later, rainy skies would help inspire Morrissey’s mopes and Kurt Cobain’s grunge. Rain is also a travelogue, taking readers to Scotland to tell the surprising story of the mackintosh raincoat, and to India, where villagers extract the scent of rain from the monsoon-drenched earth and turn it into perfume. Now, after thousands of years spent praying for rain or worshiping it; burning witches at the stake to stop rain or sacrificing small children to bring it; mocking rain with irrigated agriculture and cities built in floodplains; even trying to blast rain out of the sky with mortars meant for war, humanity has finally managed to change the rain. Only not in ways we intended. As climate change upends rainfall patterns and unleashes increasingly severe storms and drought, Barnett shows rain to be a unifying force in a fractured world. Too much and not nearly enough, rain is a conversation we share, and this is a book for everyone who has ever experienced it.

    With China on the rise, so, too, are the American cities of the West coast, including Seattle, San Francisco, and the long cluster of towns down the Silicon Valley.Today, the Pacific is ascendant. Its geological history has long transformed us—tremendous earthquakes, volcanoes, and tsunamis—but its human history, from a Western perspective, is quite young, beginning with Magellan’s sixteenth-century circumnavigation. It is a natural wonder whose most fascinating history is currently being made.In telling the story of the Pacific, Simon Winchester takes us from the Bering Strait to Cape Horn, the Yangtze River to the Panama Canal, and to the many small islands and archipelagos that lie in between. He observes the fall of a dictator in Manila, visits aboriginals in northern Queensland, and is jailed in Tierra del Fuego, the land at the end of the world. His journey encompasses a trip down the Alaska Highway, a stop at the isolated Pitcairn Islands, a trek across South Korea and a glimpse of its mysterious northern neighbor.Winchester’s personal experience is vast and his storytelling second to none. And his historical understanding of the region is formidable, making Pacific a paean to this magnificent sea of beauty, myth, and imagination that is transforming our lives.

    Contrary to what the glossy magazines would have us believe, we do not enjoy potato chips because they crunch just like the insects our forebears snacked on. As Zuk argues, such beliefs incorrectly assume that we’re stuck—finished evolving—and have been for tens of thousands of years. She draws on fascinating evidence that examines everything from adults’ ability to drink milk to the texture of our ear wax to show that we’ve actually never stopped evolving. Our nostalgic visions of an ideal evolutionary past in which we ate, lived, and reproduced as we were “meant to” fail to recognize that we were never perfectly suited to our environment. Evolution is about change, and every organism is full of trade-offs.From debunking the caveman diet to unraveling gender stereotypes, Zuk gives an analysis of widespread paleofantasies and the scientific evidence that undermines them, all the while broadening our understanding of our origins and what they can really tell us about our present and our future.