When temperatures drop below 56°F, tin crumbles into powder. Were the soldiers of the Grande Armée acutee fatally weakened by cold because the buttons of their uniforms fell apart? How different our world might be if tin did not disintegrate at low temperatures and the French had continued their eastward expansion! This fascinating book tells the stories of seventeen molecules that, like the tin of those buttons, greatly influenced the course of history. These molecules provided the impetus for early exploration and made possible the ensuing voyages of discovery. They resulted in grand feats of engineering and spurred advances in medicine; lie behind changes in gender roles, in law, and in the environment; and have determined what we today eat, drink, and wear. Showing how a change as small as the position of an atom can lead to enormous differences in the properties of a substance, the authors reveal the astonishing chemical connections among seemingly unrelated events. Napoleon's Buttons offers a novel way to understand how our contemporary world works and how our civilization has been shaped over time.

    This critically acclaimed biography offers an unprecedented look at William Masters and Virginia Johnson, their pioneering studies on intimacy, and their lasting impact on the love lives of today's men and women.

    His inventions, patents, and theoretical work formed the basis of modern AC electricity, and contributed to the development of radio and television. Like his competitor Thomas Edison, Tesla was one of America's first celebrity scientists, enjoying the company of New York high society and dazzling the likes of Mark Twain with his electrical demonstrations. An astute self-promoter and gifted showman, he cultivated a public image of the eccentric genius. Even at the end of his life when he was living in poverty, Tesla still attracted reporters to his annual birthday interview, regaling them with claims that he had invented a particle-beam weapon capable of bringing down enemy aircraft.Plenty of biographies glamorize Tesla and his eccentricities, but until now none has carefully examined what, how, and why he invented. In this groundbreaking book, W. Bernard Carlson demystifies the legendary inventor, placing him within the cultural and technological context of his time, and focusing on his inventions themselves as well as the creation and maintenance of his celebrity. Drawing on original documents from Tesla's private and public life, Carlson shows how he was an idealist inventor who sought the perfect experimental realization of a great idea or principle, and who skillfully sold his inventions to the public through mythmaking and illusion.This major biography sheds new light on Tesla's visionary approach to invention and the business strategies behind his most important technological breakthroughs.

    Today, it is the most common form of officially classified mental illness. Scott Stossel gracefully guides us across the terrain of an affliction that is pervasive yet too often misunderstood. Drawing on his own long-standing battle with anxiety, Stossel presents an astonishing history, at once intimate and authoritative, of the efforts to understand the condition from medical, cultural, philosophical, and experiential perspectives. He ranges from the earliest medical reports of Galen and Hippocrates, through later observations by Robert Burton and Søren Kierkegaard, to the investigations by great nineteenth-century scientists, such as Charles Darwin, William James, and Sigmund Freud, as they began to explore its sources and causes, to the latest research by neuroscientists and geneticists. Stossel reports on famous individuals who struggled with anxiety, as well as on the afflicted generations of his own family. His portrait of anxiety reveals not only the emotion’s myriad manifestations and the anguish anxiety produces but also the countless psychotherapies, medications, and other (often outlandish) treatments that have been developed to counteract it. Stossel vividly depicts anxiety’s human toll—its crippling impact, its devastating power to paralyze—while at the same time exploring how those who suffer from it find ways to manage and control it. My Age of Anxiety is learned and empathetic, humorous and inspirational, offering the reader great insight into the biological, cultural, and environmental factors that contribute to the affliction.

     It is a remarkable portrait, too, of the life of a psychiatric asylum--the sort of community in which, for better and for worse, hundreds of thousands of people lived out their lives.More than four hundred abandoned suitcases filled with patients’ belongings were found when Willard Psychiatric Center closed in 1995 after 125 years of operation. They are skillfully examined here and compared to the written record to create a moving—and devastating—group portrait of twentieth-century American psychiatric care.

    In this classic work Anne Sayre, a journalist and close friend of Franklin, puts the record straight.

    The adjective 'medieval' has become a synonym for brutality and uncivilized behavior. Yet without the work of medieval scholars there could have been no Galileo, no Newton and no Scientific Revolution. In God's Philosophers, James Hannam debunks many of the myths about the Middle Ages, showing that medieval people did not think the earth is flat, nor did Columbus 'prove' that it is a sphere; the Inquisition burnt nobody for their science nor was Copernicus afraid of persecution; no Pope tried to ban human dissection or the number zero. God's Philosophers is a celebration of the forgotten scientific achievements of the Middle Ages - advances which were often made thanks to, rather than in spite of, the influence of Christianity and Islam. Decisive progress was also made in technology: spectacles and the mechanical clock, for instance, were both invented in thirteenth-century Europe. Charting an epic journey through six centuries of history, God's Philosophers brings back to light the discoveries of neglected geniuses like John Buridan, Nicole Oresme and Thomas Bradwardine, as well as putting into context the contributions of more familiar figures like Roger Bacon, William of Ockham and Saint Thomas Aquinas.

    Building a house would entail no more work than planting a seed in the ground. These scenarios may seem far-fetched, but pioneering geneticist George Church and science writer Ed Regis show that synthetic biology is bringing us ever closer to making such visions a reality. In Regenesis, Church and Regis explore the possibilities—and perils—of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. Until now, nature has been the exclusive arbiter of life, death, and evolution; with synthetic biology, we now have the potential to write our own biological future. Indeed, as Church and Regis show, it even enables us to revisit crucial points in the evolution of life and, through synthetic biological techniques, choose different paths from those nature originally took. Such exploits will involve far more than just microbial tinkering. Full-blown genomic engineering will make possible incredible feats, from resurrecting woolly mammoths and other extinct organisms to creating mirror life forms with a molecular structure the opposite of our own. These technologies—far from the out-of-control nightmare depicted in science fiction—have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span. A breathtaking look at the potential of this world-changing technology, Regenesis is nothing less than a guide to the future of life.

    New findings in molecular biology challenge the gene-centered version of Darwinian theory according to which adaptation occurs only through natural selection of chance DNA variations. In Evolution in Four Dimensions, Eva Jablonka and Marion Lamb argue that there is more to heredity than genes. They trace four dimensions in evolution -- four inheritance systems that play a role in evolution: genetic, epigenetic (or non-DNA cellular transmission of traits), behavioral, and symbolic (transmission through language and other forms of symbolic communication). These systems, they argue, can all provide variations on which natural selection can act. Evolution in Four Dimensions offers a richer, more complex view of evolution than the gene-based, one-dimensional view held by many today. The new synthesis advanced by Jablonka and Lamb makes clear that induced and acquired changes also play a role in evolution. After discussing each of the four inheritance systems in detail, Jablonka and Lamb put Humpty Dumpty together again by showing how all of these systems interact. They consider how each may have originated and guided evolutionary history and they discuss the social and philosophical implications of the four-dimensional view of evolution. Each chapter ends with a dialogue in which the authors engage the contrarieties of the fictional (and skeptical) I.M., or Ifcha Mistabra -- Aramaic for the opposite conjecture -- refining their arguments against I.M.'s vigorous counterarguments. The lucid and accessible text is accompanied by artist-physician Anna Zeligowski's lively drawings, which humorously and effectively illustrate the authors' points.

    His invention of the first practical incandescent lamp 140 years ago so dazzled the world--already reeling from his invention of the phonograph and dozens of other revolutionary devices--that it cast a shadow over his later achievements. In all, this near-deaf genius ("I haven't heard a bird sing since I was twelve years old") patented 1,093 inventions, not including others, such as the X-ray fluoroscope, that he left unlicensed for the benefit of medicine.One of the achievements of this staggering new biography, the first major life of Edison in more than twenty years, is that it portrays the unknown Edison--the philosopher, the futurist, the chemist, the botanist, the wartime defense adviser, the founder of nearly 250 companies--as fully as it deconstructs the Edison of mythological memory. Edmund Morris, winner of the Pulitzer Prize and the National Book Award, brings to the task all the interpretive acuity and literary elegance that distinguished his previous biographies of Theodore Roosevelt, Ronald Reagan, and Ludwig van Beethoven. A trained musician, Morris is especially well equipped to recount Edison's fifty-year obsession with recording technology and his pioneering advances in the synchronization of movies and sound. Morris sweeps aside conspiratorial theories positing an enmity between Edison and Nikola Tesla and presents proof of their mutually admiring, if wary, relationship.Enlightened by seven years of research among the five million pages of original documents preserved in Edison's huge laboratory at West Orange, New Jersey, and privileged access to family papers still held in trust, Morris is also able to bring his subject to life on the page--the adored yet autocratic and often neglectful husband of two wives and father of six children. If the great man who emerges from it is less a sentimental hero than an overwhelming force of nature, driven onward by compulsive creativity, then Edison is at last getting his biographical due.

    In Tammet's world, numbers are beautiful and mathematics illuminates our lives and minds. Using anecdotes, everyday examples, and ruminations on history, literature, and more, Tammet allows us to share his unique insights and delight in the way numbers, fractions, and equations underpin all our lives. Inspired by the complexity of snowflakes, Anne Boleyn's eleven fingers, or his many siblings, Tammet explores questions such as why time seems to speed up as we age, whether there is such a thing as an average person, and how we can make sense of those we love. Thinking In Numbers will change the way you think about math and fire your imagination to see the world with fresh eyes.

    Though he never left Italy, his inventions and discoveries were heralded around the world. Most sensationally, his telescopes allowed him to reveal a new reality in the heavens and to reinforce the astounding argument that the Earth moves around the Sun. For this belief, he was brought before the Holy Office of the Inquisition, accused of heresy, and forced to spend his last years under house arrest. Of Galileo's three illegitimate children, the eldest best mirrored his own brilliance, industry, and sensibility, and by virtue of these qualities became his confidante. Born Virginia in 1600, she was thirteen when Galileo placed her in a convent near him in Florence, where she took the most appropriate name of Suor Maria Celeste. Her loving support, which Galileo repaid in kind, proved to be her father's greatest source of strength throughout his most productive and tumultuous years. Her presence, through letters which Sobel has translated from their original Italian and masterfully woven into the narrative, graces her father's life now as it did then. Galileo's Daughter dramatically recolors the personality and accomplishment of a mythic figure whose seventeenth-century clash with Catholic doctrine continues to define the schism between science and religion. Moving between Galileo's grand public life and Maria Celeste's sequestered world, Sobel illuminates the Florence of the Medicis and the papal court in Rome during the pivotal era when humanity's perception of its place in the cosmos was being overturned. In that same time, while the bubonic plague wreaked its terrible devastation and the Thirty Years' War tipped fortunes across Europe, one man sought to reconcile the Heaven he revered as a good Catholic with the heavens he revealed through his telescope. With all the human drama and scientific adventure that distinguished Longitude, Galileo's Daughter is an unforgettable story.

    It produced a cloud of roiling debris that blackened the sky for months as well as other geologic disasters--and triggered the demise of Tyrannosaurus rex. We know what happened largely because Walter Alvarez--synthesizing the findings of experts from a variety of scientific fields--has written a gripping story of the decades-long search for the cause of the dinosaurs' extinction. Painstakingly assembling clues from the Italian Apennines and the depths of the Pacific and presenting them with the excitement of a great novel, T. rex and the Crater of Doom is a book of undeniable importance and irresistible appeal by a major figure in contemporary science. " Engaging and witty. Read Alvarez for and excellent account of how scientists pose questions and seek to solve them." --Scientific American " First-rate...Alvarez provides the up-close tale of the comet or asteroid that wiped out the dinosaurs." --San Francisco Chronicle

    What happened during those blackouts has made Sybil's experience one of the most famous psychological cases in the world.

      In the past few years, a handful of scientists have been in a race to explain a disturbing aspect of our universe: only 4 percent of it consists of the matter that makes up you, me, our books, and every planet, star, and galaxy. The rest—96 percent of the universe—is completely unknown.   Richard Panek tells the dramatic story of how scientists reached this conclusion, and what they’re doing to find this "dark" matter and an even more bizarre substance called dark energy. Based on in-depth, on-site reporting and hundreds of interviews—with everyone from Berkeley’s feisty Saul Perlmutter and Johns Hopkins’s meticulous Adam Riess to the quietly revolutionary Vera Rubin—the book offers an intimate portrait of the bitter rivalries and fruitful collaborations, the eureka moments and blind alleys, that have fueled their search, redefined science, and reinvented the universe.