Just a half century ago, this idea was revolutionary. In April 1953, James Watson and Francis Crick published in Nature their groundbreaking work revealing the double helix structure of DNA. While this discovery received wide attention from both mainstream media and the academic community, it was just one part of the bigger story in this history of molecular biology. By the mid-1950s, the scientific community confirmed that genes were indeed comprised of DNA; they just needed to crack the genetic code—and the race was on. Life’s Greatest Secret is the full and rich history of this challenge and the characters—many of whom were not biologists—whose work contributed to this grand scientific endeavor: mathematician and father of cybernetics Norbert Wiener, physicist Erwin Schrödinger, information theorist Claude Shannon, and biologists Jacques Monod and Marshall Nirenberg.In Life’s Greatest Secret, science historian and zoologist Matthew Cobb shows that the race to crack the genetic code was mostly a matter of craft—individuals or small groups struggling with ideas and concepts as much as they were with facts, trying to find the right experiment to answer the right questions, even if they didn’t know what the questions were, and finding that, even when the most definitive answer served mostly to reveal more ignorance, whether in 1953, with Watson and Crick, or in 1961, when Nirenberg and Matthaei showed how DNA codes for specific amino acids, and again and again thereafter, or in 2000, with the first publication of a human genome. Each discovery was a leap forward in our understanding of the natural world and our place within in, akin to the discoveries of Galileo and Einstein in the realm of physics, or the publication of Darwin’s On the Origin of Species. And each served to show how much bigger the problem was that anyone had previously imagined, a trend that continues, as Cobb shows, even today, whether we are discussing gene regulation, epigenetics, or GMOs.Life’s Greatest Secret is a story of ideas and of experimentation, of ingenuity, insight, and dead-ends, in the hunt to make the greatest discovery of twentieth century biology. Ultimately, though, this is a story of humans exploring what it is that makes us human.

    H. Freeman and Company.  Visit the  Life, Eighth Edition preview site.  LIFE HAS EVOLVED. . . from its original publication to this dramatically revitalized Eighth Edition. LIFE has always shown students how biology works, offering an engaging and coherent presentation of the fundamentals of biology by describing the landmark experiments that revealed them. This edition builds on those strengths and introduces several innovations.As with previous editions, the Eighth Edition will also be available in three paperback volumes:  • Volume I: The Cell and Heredity, Chapters 1-20  • Volume II: Evolution, Diversity and Ecology, Chapters 1, 21-33, 52-57  • Volume III: Plants and Animals, Chapters 1, 34-51

    We find animals and plants where we do because, over time, the continents have moved, separating and uniting in a long, slow dance; because sea levels have risen, cutting off one bit of land from another; because new and barren volcanic islands have risen up from the sea; and because animals and plants vary greatly in their ability to travel, and separation causes the formation of new species. This is the story of how life has responded to, and has in turn altered, the ever-changing Earth. And it includes many fascinating tales--of pygmy mammoths and elephant birds and of radical ideas by bold young scientists.

    Margulis to create a vivid new picture of the world that is crucial to our understanding of the future of the planet. Addressed to general readers, the book provides a beautifully written view of evolution as a process based on interdependency and the interconnectedness of all life on the planet.

    In How to Clone a Mammoth, Beth Shapiro, evolutionary biologist and pioneer in "ancient DNA" research, walks readers through the astonishing and controversial process of de-extinction. From deciding which species should be restored, to sequencing their genomes, to anticipating how revived populations might be overseen in the wild, Shapiro vividly explores the extraordinary cutting-edge science that is being used--today--to resurrect the past. Journeying to far-flung Siberian locales in search of ice age bones and delving into her own research--as well as those of fellow experts such as Svante Paabo, George Church, and Craig Venter--Shapiro considers de-extinction's practical benefits and ethical challenges. Would de-extinction change the way we live? Is this really cloning? What are the costs and risks? And what is the ultimate goal?Using DNA collected from remains as a genetic blueprint, scientists aim to engineer extinct traits--traits that evolved by natural selection over thousands of years--into living organisms. But rather than viewing de-extinction as a way to restore one particular species, Shapiro argues that the overarching goal should be the revitalization and stabilization of contemporary ecosystems. For example, elephants with genes modified to express mammoth traits could expand into the Arctic, re-establishing lost productivity to the tundra ecosystem.Looking at the very real and compelling science behind an idea once seen as science fiction, How to Clone a Mammoth demonstrates how de-extinction will redefine conservation's future.

    In this far-reaching narrative, Weisman explains how our massive infrastructure would collapse and finally vanish without human presence; which everyday items may become immortalized as fossils; how copper pipes and wiring would be crushed into mere seams of reddish rock; why some of our earliest buildings might be the last architecture left; and how plastic, bronze sculpture, radio waves, and some man-made molecules may be our most lasting gifts to the universe.The World Without Us reveals how, just days after humans disappear, floods in New York's subways would start eroding the city's foundations, and how, as the world's cities crumble, asphalt jungles would give way to real ones. It describes the distinct ways that organic and chemically treated farms would revert to wild, how billions more birds would flourish, and how cockroaches in unheated cities would perish without us. Drawing on the expertise of engineers, atmospheric scientists, art conservators, zoologists, oil refiners, marine biologists, astrophysicists, religious leaders from rabbis to the Dalai Lama, and paleontologists—who describe a prehuman world inhabited by megafauna like giant sloths that stood taller than mammoths—Weisman illustrates what the planet might be like today, if not for us.From places already devoid of humans (a last fragment of primeval European forest; the Korean DMZ; Chernobyl), Weisman reveals Earth's tremendous capacity for self-healing. As he shows which human devastations are indelible, and which examples of our highest art and culture would endure longest, Weisman's narrative ultimately drives toward a radical but persuasive solution that needn't depend on our demise. It is narrative nonfiction at its finest, and in posing an irresistible concept with both gravity and a highly readable touch, it looks deeply at our effects on the planet in a way that no other book has.

    Anderson Thomson, Jr., MD, with Clare Aukofer, offers a succinct yet comprehensive study of how and why the human mind generates religious belief. Dr. Thomson, a highly respected practicing psychiatrist with credentials in forensic psychiatry and evolutionary psychology, methodically investigates the components and causes of religious belief in the same way any scientist would investigate the movement of astronomical bodies or the evolution of life over time—that is, as a purely natural phenomenon. Providing compelling evidence from psychology, the cognitive neurosciences, and related fields, he, with Ms. Aukofer, presents an easily accessible and exceptionally convincing case that god(s) were created by man—not vice versa. With this slim volume, Dr. Thomson establishes himself as a must-read thinker and leading voice on the primacy of reason and science over superstition and religion.

    The author of The Lives of a Cell and The Medusa and the Snail now raises challenging questions about some of the major issues of our time—AIDS, drug abuse, and aging.With extraordinary perception, author Lewis Thomas discusses topics such as evolutionary biology, the development of language, the therapeutic aspects of medicine, and his love for his profession.

    In short, we have become the dominant animal. Why, then, are we creating a world that threatens our own species? What can we do to change the current trajectory toward more climate change, increased famine, and epidemic disease?   Renowned Stanford scientists Paul R. Ehrlich and Anne H. Ehrlich believe that intelligently addressing those questions depends on a clear understanding of how we evolved and how and why we’re changing the planet in ways that darken our descendants’ future. The Dominant Animal arms readers with that knowledge, tracing the interplay between environmental change and genetic and cultural evolution since the dawn of humanity. In lucid and engaging prose, they describe how Homo sapiens adapted to their surroundings, eventually developing the vibrant cultures, vast scientific knowledge, and technological wizardry we know today.   But the Ehrlichs also explore the flip side of this triumphant story of innovation and conquest. As we clear forests to raise crops and build cities, lace the continents with highways, and create chemicals never before seen in nature, we may be undermining our own supremacy. The threats of environmental damage are clear from the daily headlines, but the outcome is far from destined. Humanity can again adapt—if we learn from our evolutionary past.   Those lessons are crystallized in The Dominant Animal. Tackling the fundamental challenge of the human predicament, Paul and Anne Ehrlich offer a vivid and unique exploration of our origins, our evolution, and our future.

    Humans have "subdued 75 per cent of the land surface, concocted a wizardry of industrial and medical marvels, strung lights all across the darkness." We now collect the DNA of vanishing species in a "frozen ark," equip orangutans with iPads, create wearable technologies and synthetic species that might one day outsmart us. With her distinctive gift for making scientific discovery intelligible to the layperson, Ackerman takes us on an exciting journey to understand this bewildering new reality, introducing us to many of the people and ideas now creating--perhaps saving--the future.The Human Ageis a surprising, optimistic engagement with the dramatic transformations that have shaped, and continue to alter, our world, our relationship with nature and our prospects for the future.

    Current estimates suggest that the rate of extinction is now thousands of times that counted in the fossil record before the emergence of modern man. At the same time, human societies themselves are in a cultural extinction crisis, with experts anticipating that of the world's nearly seven thousand languages as few as ten percent may survive into the next century. Melanie Challenger's extraordinary book is an exploration of how we might live to resist these extinctions and why such disappearances must be of concern to us. Adventurous, curious and passionate about her subject, Challenger takes us on a very personal journey as she tries to restore her own relationship with nature. The narrative unfolds through a series of landscapes haunted by extinction. From the ruined tin mines of Cornwall and the abandoned whaling stations of South Georgia to the Inuit camps of the Arctic and the white heart of Antarctica, she probes the critical relationship between human activities and environmental collapse. This is the first book to weave together the strands of cultural, biological and industrial extinctions into a meditation on the way we live beside nature in the modern world.

    These black-and-white and vibrantly colored images, many resembling abstract art, are employed daily by scientists around the world, but most have never before been seen by the general public. Each chapter addresses a different set of techniques for studying the brain as revealed through the images, and each is introduced by a leading scientist in that field of study. Author Carl Schoonover’s captions provide detailed explanations of each image as well as the major insights gained by scientists over the course of the past 20 years. Accessible to a wide audience, this book reveals the elegant methods applied to study the mind, giving readers a peek at its innermost workings, helping us to understand them, and offering clues about what may lie ahead. Praise for Portraits of the Mind: "An odyssey through the brain, illuminated by a rainbow" --New York Times "Stunning images" --Scientific American "The collection of images in the new book Portraits of the Mind is truly impressive . . . The mix of history, science and art is terrific." -Wired.com "History, science, and art come together to provide a unique perspective on what's going on upstairs." --New Yorker.com "No knowledge of the source or subject matter of these images is necessary; the book is justified by their beauty alone." --Science "A remarkable new book"- -Discover.com "John Keats's insistence that truth is beauty is exemplified by Carl Schoonover's wonderful book Portraits of the Mind. Since one cannot understand the present without examining the past, this book offers a delightful and instructive way of accomplishing just that. I enthusiastically recommend this beautiful book both to students of brain science and to lovers of art." -Eric R. Kandel, MD, Nobel Prize in Physiology or Medicine, 2000; University Professor at Columbia; Fred Kavli Professor and Director, Kavli Institute for Brain Science; Senior Investigator at the Howard Hughes Medical Institute; and author of In Search of Memory: The Emergence of a New Science of Mind "Portraits of the Mind achieves a rare combination of beauty and knowledge. Its images of the brain are mesmerizing, from medieval engravings to modern visualizations as gorgeously abstract as anything by Rothko or de Kooning. And in explaining the nature of these images, this book also delivers an enlightening, up-to-date history of neuroscience." -Carl Zimmer, author of Soul Made Flesh: The Discovery of the Brain-and How It Changed the World and The Mind's Eye Goes Blind: Fifteen Journeys Through the Brain "Portraits of the Mind is a remarkable book that combines beautifully reproduced illustrations of the nervous system as it has been visualized over the centuries, as well as lively and authoritative commentaries by some of today's leading neuroscientists. It will be enjoyed by professionals and general readers alike." --Dale Purves, MD, Professor of Neurobiology, Psychology and Neuroscience; and Philosophy at Duke University

    How to approach complex normal and abnormal behaviors through biology. How to integrate disciplines including sociobiology, ethology, neuroscience, and endocrinology to examine behaviors such as aggression, sexual behavior, language use, and mental illness.36 hours lectures

    But in The Music of Life, world renowned physiologist Denis Noble argues that, to truly understand life, we must look beyondthe selfish gene to consider life on a much wider variety of levels. Life, Noble asserts, is a kind of music, a symphonic interplay between genes, cells, organs, body, and environment. He weaves this musical metaphor throughout this personal and deeply lyrical work, illuminating ideas that might otherwise be daunting to non-scientists. In elegant prose, Noblesets out a cutting-edge alternative to the gene's eye view, offering a radical switch of perception in which genes are seen as prisoners and the organism itself is a complex system of many interacting levels. In his more expansive view, life emerges as a process, the ebb and flow of activity in anintricate web of connections. He introduces readers to the realm of systems biology, a field that has been growing in strength in the past decade. Noble, himself one of the founders of this field, argues modern systems biology may be the view we need to adopt to gain a deeper understanding of thenature of life. Drawing on his experiences in his research on the heartbeat, and on evolutionary biology, development, medicine, philosophy, linguistics, and Chinese culture, Noble presents us with a profound and very modern reflection on the nature of life.

    Radiometric dating of nearby rocks indicated the skeleton, classified as Ardipithecus ramidus, was 4.4 million years old, more than a million years older than "Lucy," then the oldest known human ancestor. The findings challenged many assumptions about human evolution--how we started walking upright, how we evolved our nimble hands, and, most significantly, whether we were descended from an ancestor that resembled today's chimpanzee--and repudiated a half-century of paleoanthropological orthodoxy.Fossil Men is the first full-length exploration of Ardi, the fossil men who found her, and her impact on what we know about the origins of the human species. It is a scientific detective story played out in anatomy and the natural history of the human body. Kermit Pattison brings into focus a cast of eccentric, obsessive scientists, including one of the world's greatest fossil hunters, Tim White--an exacting and unforgiving fossil hunter whose virtuoso skills in the field were matched only by his propensity for making enemies; Gen Suwa, a Japanese savant who sometimes didn't bother going home at night to devote more hours to science; Owen Lovejoy, a onetime creationist-turned-paleoanthropologist; Berhane Asfaw, who survived imprisonment and torture to become Ethiopia's most senior paleoanthropologist and who fought for African scientists to gain equal footing in the study of human origins; and the Leakeys, for decades the most famous family in paloanthropology.An intriguing tale of scientific discovery, obsession and rivalry that moves from the sun-baked desert of Africa and a nation caught in a brutal civil war, to modern high-tech labs and academic lecture halls, Fossil Men is popular science at its best, and a must read for fans of Jared Diamond, Richard Dawkins, and Edward O. Wilson.