Just a half century ago, this idea was revolutionary. In April 1953, James Watson and Francis Crick published in Nature their groundbreaking work revealing the double helix structure of DNA. While this discovery received wide attention from both mainstream media and the academic community, it was just one part of the bigger story in this history of molecular biology. By the mid-1950s, the scientific community confirmed that genes were indeed comprised of DNA; they just needed to crack the genetic code—and the race was on. Life’s Greatest Secret is the full and rich history of this challenge and the characters—many of whom were not biologists—whose work contributed to this grand scientific endeavor: mathematician and father of cybernetics Norbert Wiener, physicist Erwin Schrödinger, information theorist Claude Shannon, and biologists Jacques Monod and Marshall Nirenberg.In Life’s Greatest Secret, science historian and zoologist Matthew Cobb shows that the race to crack the genetic code was mostly a matter of craft—individuals or small groups struggling with ideas and concepts as much as they were with facts, trying to find the right experiment to answer the right questions, even if they didn’t know what the questions were, and finding that, even when the most definitive answer served mostly to reveal more ignorance, whether in 1953, with Watson and Crick, or in 1961, when Nirenberg and Matthaei showed how DNA codes for specific amino acids, and again and again thereafter, or in 2000, with the first publication of a human genome. Each discovery was a leap forward in our understanding of the natural world and our place within in, akin to the discoveries of Galileo and Einstein in the realm of physics, or the publication of Darwin’s On the Origin of Species. And each served to show how much bigger the problem was that anyone had previously imagined, a trend that continues, as Cobb shows, even today, whether we are discussing gene regulation, epigenetics, or GMOs.Life’s Greatest Secret is a story of ideas and of experimentation, of ingenuity, insight, and dead-ends, in the hunt to make the greatest discovery of twentieth century biology. Ultimately, though, this is a story of humans exploring what it is that makes us human.

    But are there limits to what we can discover about our physical universe?In this very personal journey to the edges of knowledge, Marcus du Sautoy investigates how leading experts in fields from quantum physics and cosmology, to sensory perception and neuroscience, have articulated the current lie of the land. In doing so, he travels to the very boundaries of understanding, questioning contradictory stories and consulting cutting edge data.Is it possible that we will one day know everything? Or are there fields of research that will always lie beyond the bounds of human comprehension? And if so, how do we cope with living in a universe where there are things that will forever transcend our understanding?In What We Cannot Know, Marcus du Sautoy leads us on a thought-provoking expedition to the furthest reaches of modern science. Prepare to be taken to the edge of knowledge to find out if there’s anything we truly cannot know.

    The book was based on a course of public lectures delivered by Schrödinger in February 1943 at Trinity College, Dublin. Schrödinger's lecture focused on one important question: "how can the events in space and time which take place within the spatial boundary of a living organism be accounted for by physics and chemistry?" In the book, Schrödinger introduced the idea of an "aperiodic crystal" that contained genetic information in its configuration of covalent chemical bonds. In the 1950s, this idea stimulated enthusiasm for discovering the genetic molecule and would give both Francis Crick and James Watson initial inspiration in their research.

    In all the current highly publicized debates about creationism and its descendant "intelligent design," there is an element of the controversy that is rarely mentioned—the "evidence," the empirical truth of evolution by natural selection. Even Richard Dawkins and Stephen Jay Gould, while extolling the beauty of evolution and examining case studies, have not focused on the evidence itself. Yet the proof is vast, varied, and magnificent, drawn from many different fields of science. Scientists are observing species splitting into two and are finding more and more fossils capturing change in the past—dinosaurs that have sprouted feathers, fish that have grown limbs. Why Evolution Is True weaves together the many threads of modern work in genetics, paleontology, geology, molecular biology, and anatomy that demonstrate the "indelible stamp" of the processes first proposed by Darwin. In crisp, lucid prose accessible to a wide audience, Why Evolution Is True dispels common misunderstandings and fears about evolution and clearly confirms that this amazing process of change has been firmly established as a scientific truth.

     Three and a half billion years ago, Mars resembled earth. It was warm and wet and could have supported primitive organisms. If life once existed on Mars, might it have originated there and traveled to earth inside meteorites blasted into space by cosmic impacts? Davies builds on recent scientific discoveries and theories to address larger questions of existence: What, exactly, is life? Is it the inevitable by-product of physical laws, as many scientists maintain, or an almost miraculous accident? Are we alone in the universe, or will life emerge on all earthlike planets? And if there is life elsewhere in the universe, is it preordained to evolve toward greater complexity and intelligence? Through his search for answers to these questions, Davies explores the ultimate mystery of mankind's existence -- who we are and what our place might be in the unfolding drama of the cosmos.

    New emphasis has been given to complexity, networks, and patterns of organisation, leading to a novel kind of 'systemic' thinking. This volume integrates the ideas, models, and theories underlying the systems view of life into a single coherent framework. Taking a broad sweep through history and across scientific disciplines, the authors examine the appearance of key concepts such as autopoiesis, dissipative structures, social networks, and a systemic understanding of evolution. The implications of the systems view of life for health care, management, and our global ecological and economic crises are also discussed. Written primarily for undergraduates, it is also essential reading for graduate students and researchers interested in understanding the new systemic conception of life and its implications for a broad range of professions - from economics and politics to medicine, psychology and law.

    

    But ask what it means, and the result will be a brawl. For a century, most physicists have followed Niels Bohr's Copenhagen interpretation and dismissed questions about the reality underlying quantum physics as meaningless. A mishmash of solipsism and poor reasoning, Copenhagen endured, as Bohr's students vigorously protected his legacy, and the physics community favored practical experiments over philosophical arguments. As a result, questioning the status quo long meant professional ruin. And yet, from the 1920s to today, physicists like John Bell, David Bohm, and Hugh Everett persisted in seeking the true meaning of quantum mechanics. What Is Real? is the gripping story of this battle of ideas and of the courageous scientists who dared to stand up for truth.

    In Dyson's view, science and religion are two windows through which we can look out at the world around us. The book is a revised version of a series of the Gifford Lectures under the title "In Praise of Diversity" given at Aberdeen, Scotland. They allowed Dyson the license to express everything in the universe, which he divided into two parts in polished prose: focusing on the diversity of the natural world as the first, and the diversity of human reactions as the second half.Chapter 1 is a brief explanation of Dyson's attitudes toward religion and science. Chapter 2 is a one–hour tour of the universe that emphasizes the diversity of viewpoints from which the universe can be encountered as well as the diversity of objects which it contains. Chapter 3 is concerned with the history of science and describes two contrasting styles in science: one welcoming diversity and the other deploring it. He uses the cities of Manchester and Athens as symbols of these two ways of approaching science. Chapter 4, concerned with the origin of life, describes the ideas of six illustrious scientists who have struggled to understand the nature of life from various points of view. Chapter 5 continues the discussion of the nature and evolution of life. The question of why life characteristically tends toward extremes of diversity remains central in all attempts to understand life's place in the universe. Chapter 6 is an exercise in eschatology, trying to define possible futures for life and for the universe, from here to infinity. In this chapter, Dyson crosses the border between science and science fiction and he frames his speculations in a slightly theological context.

    . . A tour de force of a book that begs to be seen as well as to be read."--The Washington Post Book WorldWorld renowned scientist Carl Sagan and acclaimed author Ann Druyan have written a Roots for the human species, a lucid and riveting account of how humans got to be the way we are. Shadows of Forgotten Ancestors is a thrilling saga that starts with the origin of the Earth. It shows with humor and drama that many of our key traits--self-awareness, technology, family ties, submission to authority, hatred for those a little different from ourselves, reason, and ethics--are rooted in the deep past, and illuminated by our kinship with other animals.Sagan and Druyan conduct a breathtaking journey through space and time, zeroing in on critical turning points in evolutionary history, and tracing the origins of sex, altruism, violence, rape, and dominance. Their book culminates in a stunningly original examination of the connection between primate and human traits. Astonishing in its scope, brilliant in its insights, and an absolutely compelling read, Shadows of Forgotten Ancestors is a triumph of popular science.

    Two scientists explore the potential of a revolutionary genetics technology capable of easily and affordably manipulating DNA in human embryos to prevent specific diseases, addressing key concerns about related ethical and societal repercussions.

    Conway Morris is one of the few paleontologists ever to explore the Burgess Shale, having been involved in the dig since 1972, and thus he is an ideal guide to this amazing discovery. Indeed, he provides a complete overview of this remarkable find, ranging from an informative, basic discussion of the origins of life and animals on earth, to a colorful description of Charles Walcott's discovery of the Burgess Shale and of the painstaking scientific work that went on there (as well as in Burgess collections held at Harvard and the Smithsonian), to an account of similar fossil finds in Greenland and in China. The heart of the book is an imaginative trip in a time machine, back to the Cambrian seas, where the reader sees first-hand the remarkable diversity of life as it existed then. And perhaps most important, Conway Morris examines the lessons to be learned from the Burgess Shale, especially as they apply to modern evolutionary thinking. In particular, he critiques the ideas of Stephen Jay Gould, whose best-selling book Wonderful Life drew on Conway Morris's Burgess Shale work. The author takes a fresh look at the evidence and draws quite different conclusions from Gould on the nature of evolution. This finely illustrated volume takes the reader to the forefront of paleontology as it provides fresh insights into the nature of evolution and of life on earth.

    In What Is Life?, he takes up the challenge of describing what it means to be alive in a way that every reader can understand.It is a shared journey of discovery; step-by-step Nurse illuminates five great ideas that underpin biology—the Cell, the Gene, Evolution by Natural Selection, Life as Chemistry, and Life as Information. He introduces the scientists who made the most important advances, and, using his personal experiences in and out of the lab, he shares with us the challenges, the lucky breaks, and the thrilling eureka moments of discovery.Nurse writes with delight at life’s richness and with a sense of the urgent role of biology in our time. To survive the challenges that face us all today—climate change, pandemic, loss of biodiversity and food security—it is vital that we all understand what life is.

    The 10,000 Year Explosion: How Civilization Accelerated Human Evolution

    James Cleaves II seek to answer the most crucial question in science: How did life begin? They trace the trials and triumphs of the iconoclastic scientists who have sought to solve the mystery, from Darwin’s theory of evolution to Crick and Watson’s unveiling of DNA. This fascinating exploration not only examines the origin-of-life question, but also interrogates the very nature of scientific discovery and objectivity.