This easy-to-follow guide leads you step by step through every bioinformatics task that can be done over the Internet. Forget long equations, computer-geek gibberish, and installing bulky programs that slow down your computer. You'll be amazed at all the things you can accomplish just by logging on and following these trusty directions. You get the tools you need to:Analyze all types of sequences Use all types of databases Work with DNA and protein sequences Conduct similarity searches Build a multiple sequence alignment Edit and publish alignments Visualize protein 3-D structures Construct phylogenetic trees This up-to-date second edition includes newly created and popular databases and Internet programs as well as multiple new genomes. It provides tips for using servers and places to seek resources to find out about what's going on in the bioinformatics world. Bioinformatics For Dummies will show you how to get the most out of your PC and the right Web tools so you'll be searching databases and analyzing sequences like a pro!

    I wrote this book for three major reasons: (1) to help move business and technology planning from a systems and process-level view to a more strategy-driven enterprise-level view, (2) to promote and explain the emerging profession of EA, and (3) to provide the first textbook on the subject of EA, which is suitable for graduate and undergraduate levels of study. To date, other books on EA have been practitioner books not specifically oriented toward a student who may be learning the subject with little to no previous exposure. Therefore, this book contains references to related academic research and industry best practices, as well as my own observations about potential future practices and the direction of this emerging profession.

    1,200 pages of up-to-date information correlates with both the hardware and operating system exams and serves as a reference after the test-taking is completed.The minibooks cover each domain of the exam: A+ Groundwork, Inside the Box, Outside the Box, Maintenance and Troubleshooting, Operating System Basics, Managing The Operating System, Recovering Systems, Networking, and Securing Systems. You'll find plenty of sample test questions to get you prepared, too. CompTIA's A+ certification is vendor-neutral and validates the skills of entry-level computer technicians; it can be the ticket to a new or better job Certification requires successful completion of two exams; this prep guide covers all the core competencies required Nine minibooks cover A+ Groundwork, Inside the Box, Outside the Box, Maintenance and Troubleshooting, Operating System Basics, Managing The Operating System, Recovering Systems, Networking, and Securing Systems Covers installation, configuration, diagnosing, preventive maintenance, and basic networking, with extra information about Vista and a heavier emphasis on hardware Companion CD-ROM include the Dummies Test Engine, an exclusive, fully customizable test-prep software package that includes 400 exam review questions CompTIA A+ Certification All-In-One For Dummies, 2nd Edition is the best study guide to have as you prepare for the A+ exams!Note: CD-ROM/DVD and other supplementary materials are not included as part of eBook file.

    You can use JavaScript to create dynamic, interactive applications that run completely within a web browser. JavaScript is also the language of choice for developing Dynamic HTML content. Because its syntax is based on the popular programming languages C, C++, and Java, JavaScript is familiar and easy to learn for experienced programmers. At the same time, it's an interpreted scripting language, providing a flexible, forgiving programming environment for new programmers. The JavaScript Pocket Reference, 2nd Edition, provides a complete overview of the core JavaScript language and client-side scripting environment, as well as quick-reference material on core and client-side objects, methods, and properties. The new edition has been revised to cover JavaScript 1.5, and is particularly useful for developers working with the standards-compliant web browsers, such as Internet Explorer 6, Netscape 7, and Mozilla. Ideal as an introduction for beginners and a quick reference for advanced developers, this pocket-sized book is easy to take anywhere and serves as the perfect companion volume to the bestselling JavaScript: The Definitive Guide, 4th Edition. O'Reilly's Pocket References have become a favorite among developers everywhere. By providing a wealth of important details in a concise, well-organized format, these handy books deliver just what you need to complete the task at hand. When you've reached a sticking point and need to get to the answer quickly, the new JavaScript Pocket Reference is the book you'll want close at hand.

    Design patterns are time-tested solutions to recurring problems, letting the designer build programs on solutions that have already proved effective Provides developers with more than a dozen ASP.NET examples showing standard design patterns and how using them helpsbuild a richer understanding of ASP.NET architecture, as well as better ASP.NET applications Builds a solid understanding of ASP.NET architecture that can be used over and over again in many projects Covers ASP.NET code to implement many standard patterns including Model-View-Controller (MVC), ETL, Master-Master Snapshot, Master-Slave-Snapshot, Facade, Singleton, Factory, Single Access Point, Roles, Limited View, observer, page controller, common communication patterns, and more

    With more traditional web servers becoming obsolete, having knowledge on servers that achieve high scalability and optimal resource consumption using Node.js is the key to your app development success. Teaching you the essentials to making event-driven server-side apps, this book demonstrates how you can use less space and take less time for communication between web client and server.Contains numerous hands-on examples Explains implementation of real-time apps including Socket.IO and HTML5, and WebSockets Addresses practical Node.js advantages from specific design choices Demonstrates why knowledge and use of JavaScript is beneficial Includes an interactive online component with sample chapters Explains components of stand out apps including brevity and benchmarks Looking to enhance your abilities even further? Smashing Node.js: JavaScript Everywhere makes developing server-side apps accessible with its focus on JavaScript, open source, and easy-to-use language.

    Best-selling author Robin Williams's simple, logical principles for using type to produce beautiful, professional documents are as true now as they were when the original edition was published in 1989. This updated edition includes new examples and expanded information dedicated to the practical advice that made the first edition an enduring bestseller. Throughout, Robin shows you the small details that separate the pros from the amateurs: typographer versus typewriter quotation marks, en and em dashes, tabs and indents, kerning, leading, white space, widows and orphans, and hanging punctuation. If you prepare documents, you'll find The Mac is not a typewriter, Second Edition an indispensable guide. And those who read your documents will recognize the work of a pro, even if they don't know a curly quote from curly fries.

    Updated for Python 3, this expanded edition shows you how to locate performance bottlenecks and significantly speed up your code in high-data-volume programs. By exploring the fundamental theory behind design choices, High Performance Python helps you gain a deeper understanding of Python's implementation.How do you take advantage of multicore architectures or clusters? Or build a system that scales up and down without losing reliability? Experienced Python programmers will learn concrete solutions to many issues, along with war stories from companies that use high-performance Python for social media analytics, productionized machine learning, and more.Get a better grasp of NumPy, Cython, and profilersLearn how Python abstracts the underlying computer architectureUse profiling to find bottlenecks in CPU time and memory usageWrite efficient programs by choosing appropriate data structuresSpeed up matrix and vector computationsUse tools to compile Python down to machine codeManage multiple I/O and computational operations concurrentlyConvert multiprocessing code to run on local or remote clustersDeploy code faster using tools like Docker

    This practical guide shows how Apache ZooKeeper helps you manage distributed systems, so you can focus mainly on application logic. Even with ZooKeeper, implementing coordination tasks is not trivial, but this book provides good practices to give you a head start, and points out caveats that developers and administrators alike need to watch for along the way.In three separate sections, ZooKeeper contributors Flavio Junqueira and Benjamin Reed introduce the principles of distributed systems, provide ZooKeeper programming techniques, and include the information you need to administer this service.Learn how ZooKeeper solves common coordination tasksExplore the ZooKeeper API’s Java and C implementations and how they differUse methods to track and react to ZooKeeper state changesHandle failures of the network, application processes, and ZooKeeper itselfLearn about ZooKeeper’s trickier aspects dealing with concurrency, ordering, and configurationUse the Curator high-level interface for connection managementBecome familiar with ZooKeeper internals and administration tools

    Maybe you’ve played with the basics or written a few macros. Now you want to take it to the next level. This book is a guided series of metaprogramming tutorials that take you step by step to metaprogramming mastery. You’ll extend Elixir with powerful features and write faster, more maintainable programs in ways unmatched by other languages.You’ll start with the basics of Elixir’s metaprogramming system and find out how macros interact with Elixir’s abstract format. Then you’ll extend Elixir with your own first-class features, write a testing framework, and discover how Elixir treats source code as building blocks, rather than rote lines of instructions. You’ll continue your journey by using advanced code generation to create essential libraries in strikingly few lines of code. Finally, you’ll create domain-specific languages and learn when and where to apply your skills effectively.When you’re done, you will have mastered metaprogramming, gained insights into Elixir’s internals, and have the confidence to leverage macros to their full potential in your own projects.

    Due to their monopoly position in web browsers, and the fact web browsers have spread from PCs to phones, tablets and TVs; their status will continue to grow and grow. Despite their success, many software engineers are apprehensive about JavaScript and HTML. This apprehensiveness is not completely unfounded; both JavaScript and HTML were rushed in their early years, and driven by commercial rather than engineering interests. As a result, many dubious features crept into these languages. Due to backwards compatibility concerns, most of these features still remain. In addition, many software engineers have used these languages without ever learning them. JavaScript and HTML have low barriers to entry, and this, along with their similarity to other languages, led many software engineers to conclude that there really was nothing much to learn. If you have not used JavaScript and HTML for a number of years, or if you are a programmer or software engineer using other languages, you may be surprised at what they now offer. Browser based web applications are now capable of matching or exceeding the sophistication and scale of traditional desktop applications. In order to create complex web applications however, it is essential to learn these languages. This book takes the point of view that once you have a strong grasp of the fundamentals, the details will take care of themselves. It will not present you with long lists of APIs, or intricate details of every attribute, these can be found in reference manuals. It will focus on the details of each language that are fundamental to understanding how they work. This book will guide you through the process of developing a web application using HTML5, Javascript, jQuery and CSS. It contains the following content: 1. An introduction to the HTML5 markup language, and how it differs from HTML4 and XHTML. 2. An introduction to JavaScript, including an in-depth look at its use of objects and functions, along with the design patterns that support the development of robust web applications. 3. An introduction to jQuery selection, traversal, manipulation and events. 4. An in-depth look at the Web storage and IndexedDB APIs for client side data storage. 5. A guide to implementing offline web applications with the Application Cache API. 6. An introduction to the ways JavaScript can interact with the users file-system using the FileReader API. 7. The use of Web Workers in a web application to execute algorithms on background threads. 8. An introduction to AJAX, and the jQuery API supporting AJAX. 9. An introduction to Server Sent Events and Web Sockets. All subjects are introduced in the context of a sample web application. This book is intended for anyone with at least a superficial knowledge of HTML and programming.

    It runs on PCs rather than servers and is ideal for small- to mid-sized businesses and households. But Access is still intimidating to learn. It doesn't help that each new version crammed in yet another set of features; so many, in fact, that even the pros don't know where to find them all. Access 2007 breaks this pattern with some of the most dramatic changes users have seen since Office 95. Most obvious is the thoroughly redesigned user interface, with its tabbed toolbar (or "Ribbon") that makes features easy to locate and use. The features list also includes several long-awaited changes. One thing that hasn't improved is Microsoft's documentation. To learn the ins and outs of all the features in Access 2007, Microsoft merely offers online help.Access 2007: The Missing Manual was written from the ground up for this redesigned application. You will learn how to design complete databases, maintain them, search for valuable nuggets of information, and build attractive forms for quick-and-easy data entry. You'll even delve into the black art of Access programming (including macros and Visual Basic), and pick up valuable tricks and techniques to automate common tasks -- even if you've never touched a line of code before. You will also learn all about the new prebuilt databases you can customize to fit your needs, and how the new complex data feature will simplify your life. With plenty of downloadable examples, this objective and witty book will turn an Access neophyte into a true master.

    When it comes to creating websites, the PHP scripting language is truly a red-hot property. In fact, PHP is currently used on more than 19 million websites, surpassing Microsoft's ASP .NET technology in popularity. Programmers love its flexibility and speed; designers love its accessibility and convenience. As the industry standard book on PHP, all of the essentials are covered in a clear and concise manner. Language syntax and programming techniques are coupled with numerous examples that illustrate both correct usage and common idioms. With style tips and practical programming advice, this book will help you become not just a PHP programmer, but a good PHP programmer. Programming PHP, Second Edition covers everything you need to know to create effective web applications with PHP. Contents include: Detailed information on the basics of the PHP language, including data types, variables, operators, and flow control statements Chapters outlining the basics of functions, strings, arrays, and objects Coverage of common PHP web application techniques, such as form processing and validation, session tracking, and cookies Material on interacting with relational databases, such as MySQL and Oracle, using the database-independent PEAR DB library and the new PDO Library Chapters that show you how to generate dynamic images, create PDF files, and parse XML files with PHP Advanced topics, such as creating secure scripts, error handling, performance tuning, and writing your own C language extensions to PHP A handy quick reference to all the core functions in PHP and all the standard extensions that ship with PHP Praise for the first edition: "If you are just getting into the dynamic Web development world or you are considering migrating from another dynamic web product to PHP, Programming PHP is the book of choice to get you up, running, and productive in a short time."--Peter MacIntrye, eWeek "I think this is a great book for programmers who want to start developing dynamic websites with PHP. It gives a detailed overview of PHP, lots of valuable tips, and a good sense of PHP's strengths."--David Dooling, Slashdot.org

    This classic book uncovers what interviews are really like at America's top software and computer companies and provides you with the tools to succeed in any situation. The authors take you step-by-step through new problems and complex brainteasers they were asked during recent technical interviews. 50 interview scenarios are presented along with in-depth analysis of the possible solutions. The problem-solving process is clearly illustrated so you'll be able to easily apply what you've learned during crunch time. You'll also find expert tips on what questions to ask, how to approach a problem, and how to recover if you become stuck. All of this will help you ace the interview and get the job you want.What you will learn from this bookTips for effectively completing the job application Ways to prepare for the entire programming interview process How to find the kind of programming job that fits you best Strategies for choosing a solution and what your approach says about you How to improve your interviewing skills so that you can respond to any question or situation Techniques for solving knowledge-based problems, logic puzzles, and programming problems Who this book is for This book is for programmers and developers applying for jobs in the software industry or in IT departments of major corporations.Wrox Beginning guides are crafted to make learning programming languages and technologies easier than you think, providing a structured, tutorial format that will guide you through all the techniques involved.

    Using the concise, scenario-driven style pioneered in Scott Meyers' best-selling Effective C++, Matt Galloway brings together 52 Objective-C best practices, tips, shortcuts, and realistic code examples that are available nowhere else. Through real-world examples, Galloway uncovers little-known Objective-C quirks, pitfalls, and intricacies that powerfully impact code behavior and performance. You'll learn how to choose the most efficient and effective way to accomplish key tasks when multiple options exist, and how to write code that's easier to understand, maintain, and improve. Galloway goes far beyond the core language, helping you integrate and leverage key Foundation framework classes and modern system libraries, such as Grand Central Dispatch. Coverage includes Optimizing interactions and relationships between Objective-C objects Mastering interface and API design: writing classes that feel "right at home" Using protocols and categories to write maintainable, bug-resistant code Avoiding memory leaks that can still occur even with Automatic Reference Counting (ARC) Writing modular, powerful code with Blocks and Grand Central Dispatch Leveraging differences between Objective-C protocols and multiple inheritance in other languages Improving code by more effectively using arrays, dictionaries, and sets Uncovering surprising power in the Cocoa and Cocoa Touch frameworks