But things changed dramatically when he began suffering from inexplicable fatigue. In a matter of weeks, his organs were failing and he was read his last rites. Doctors were baffled by his condition, which they had yet to even diagnose. Floating in and out of consciousness, Fajgenbaum prayed for a second chance, the equivalent of a dramatic play to second the game into overtime.Miraculously, Fajgenbaum survived--only to endure repeated near-death relapses from what would eventually be identified as a form of Castleman disease, an extremely deadly and rare condition that acts like a cross between cancer and an autoimmune disorder. When he relapsed while on the only drug in development and realized that the medical community was unlikely to make progress in time to save his life, Fajgenbaum turned his desperate hope for a cure into concrete action: Between hospitalizations he studied his own charts and tested his own blood samples, looking for clues that could unlock a new treatment. With the help of family, friends, and mentors, he also reached out to other Castleman disease patients and physicians, and eventually came up with an ambitious plan to crowdsource the most promising research questions and recruit world-class researchers to tackle them. Instead of waiting for the scientific stars to align, he would attempt to align them himself.More than five years later and now married to his college sweetheart, Fajgenbaum has seen his hard work pay off: A treatment he identified has induced a tentative remission and his novel approach to collaborative scientific inquiry has become a blueprint for advancing rare disease research. His incredible story demonstrates the potency of hope, and what can happen when the forces of determination, love, family, faith, and serendipity collide.

    Now, she's clean and sober, a married mother of three. As she found her way in her new life, she started sharing on social media as an outlet for her depression and anxiety. She struck a chord, several of her videos went viral (one with 46million views), and in the past year her following exploded from a few hundred thousand to more than 3 million.The memoir opens in the Florida women's prison where Tiffany was incarcerated for 180 days. The memoir flashes back in time to the events that led to Tiffany's imprisonment (during the time of her active addiction, Tiffany was dating and living with a cop), and moves forward to her eventual sobriety.

    The case would become one of the most famous in modern medicine—and a total failure. As Nature Made Him tells the extraordinary story of David Reimer, who, when finally informed of his medical history, made the decision to live as a male. A macabre tale of medical arrogance, it is first and foremost a human drama of one man's—and one family's—amazing survival in the face of terrible odds.

    A successful journalist and mother to four children, she had spent her whole life feeling as if she were running a different operating system to those around her. This book charts a year in her life and offers a unique insight into the autistic mind and the journey from diagnosis to acceptance. Drawing on personal experience, research and conversations with experts, she learns how 'different' doesn't need to mean 'less' and how it's never too late for any of us to find our place in the world. Laura explores how and why female autism is so under-diagnosed and very different to that seen in men and boys and explores difficulties and benefits neurodiversity can bring.

    Her recording of Prince's Nothing Compares 2 U made her a global icon. She outraged millions when she tore up a photograph of Pope John Paul II on American television.O'Connor was unapologetic and impossible to ignore, calling out hypocrisy wherever she saw it.She has remained that way for three decades.Now, in Rememberings, O'Connor tells her story - the heartache of growing up in a family falling apart; her early forays into the Dublin music scene; her adventures and misadventures in the world of sex, drugs and rock'n'roll; the fulfilment of being a mother; her ongoing spiritual quest - and through it all, her abiding passion for music.Rememberings is intimate, replete with candid anecdotes and full of hard-won insights. It is a unique and remarkable chronicle by a unique and remarkable artist.

    Knowing a kindred spirit when he met one, Mozart wrote "That was wonderful" in his journal and took the bird home to be his pet. For three years Mozart and his family enjoyed the uniquely delightful company of the starling until one fitful April when the bird passed away.In 2013, Lyanda Lynn Haupt, author of Crow Planet, rescued her own starling, Carmen, who has become a part of her family. In Mozart's Starling, Haupt explores the unlikely bond between one of history's most controversial characters and one of history's most notoriously disliked birds. Part natural history, part story, Mozart's Starling will delight readers as they learn about language, music, and the secret world of starlings. A charming story of Mozart and his pet starling, along with a natural history of the bird.

    Doubtfire—as a brilliant new chronicler of the experience that is growing up young and female.   Mara Wilson has always felt a little young and a little out of place: as the only child on a film set full of adults, the first daughter in a house full of boys, the sole clinically depressed member of the cheerleading squad, a valley girl in New York and a neurotic in California, and one of the few former child actors who has never been in jail or rehab. Tackling everything from how she first learned about sex on the set of Melrose Place, to losing her mother at a young age, to getting her first kiss (or was it kisses?) on a celebrity canoe trip, to not being “cute” enough to make it in Hollywood, these essays tell the story of one young woman’s journey from accidental fame to relative (but happy) obscurity. But they also illuminate a universal struggle: learning to accept yourself, and figuring out who you are and where you belong. Exquisitely crafted, revelatory, and full of the crack comic timing that has made Mara Wilson a sought-after live storyteller and Twitter star, Where Am I Now? introduces a witty, perceptive, and refreshingly candid new literary voice.

    "Here’s a partial list of things I don’t believe in: God. The Devil. Heaven. Hell. Bigfoot. Ancient Aliens. Past lives. Life after death. Vampires. Zombies. Reiki. Homeopathy. Rolfing. Reflexology. Note that 'witches' and 'witchcraft' are absent from this list. The thing is, I wouldn’t believe in them, and I would privately ridicule any idiot who did, except for one thing: I am a witch."For as long as Augusten Burroughs could remember, he knew things he shouldn't have known. He manifested things that shouldn't have come to pass. And he told exactly no one about this, save one person: his mother. His mother reassured him that it was all perfectly normal, that he was descended from a long line of witches, going back to the days of the early American colonies. And that this family tree was filled with witches. It was a bond that he and his mother shared--until the day she left him in the care of her psychiatrist to be raised in his family (but that's a whole other story). After that, Augusten was on his own. On his own to navigate the world of this tricky power; on his own to either use or misuse this gift.From the hilarious to the terrifying, Toil & Trouble is a chronicle of one man's journey to understand himself, to reconcile the powers he can wield with things with which he is helpless. There are very few things that are coincidences, as you will learn in Toil & Trouble. Ghosts are real, trees can want to kill you, beavers are the spawn of Satan, houses are alive, and in the end, love is the most powerful magic of all.

    Animal combines autobiography and evolutionary history to create a funny, fascinating insight into the forces that mould and affect modern women.Animal is entertaining and informative, personal and universal – silly about lots of things and serious about some. It's a laugh-out-loud investigation to help us understand and forgive our animal urges and insecurities.

    She woke up one morning and her entire history—the life she had lived—crumbled beneath her.Inheritance is a book about secrets—secrets within families, kept out of shame or self-protectiveness; secrets we keep from one another in the name of love. It is the story of a woman’s urgent quest to unlock the story of her own identity, a story that has been scrupulously hidden from her for more than fifty years, years she had spent writing brilliantly, and compulsively, on themes of identity and family history. It is a book about the extraordinary moment we live in—a moment in which science and technology have outpaced not only medical ethics but also the capacities of the human heart to contend with the consequences of what we discover.

    In 1887, 23-year-old reporter Nellie Bly had herself committed to a New York City asylum for 10 days to expose the horrific conditions for 19th-century century mental patients.

    Now, in a darkly funny and bracing memoir, Valenti explores the toll that sexism takes from the every day to the existential. Sex Object explores the painful, funny, embarrassing, and sometimes illegal moments that shaped Valenti’s adolescence and young adulthood in New York City, revealing a much shakier inner life than the confident persona she has cultivated as one of the most recognizable feminists of her generation. In the tradition of writers like Joan Didion and Mary Karr, this literary memoir is sure to shock those already familiar with Valenti’s work and enthrall those who are just finding it.

     It is a remarkable portrait, too, of the life of a psychiatric asylum--the sort of community in which, for better and for worse, hundreds of thousands of people lived out their lives.More than four hundred abandoned suitcases filled with patients’ belongings were found when Willard Psychiatric Center closed in 1995 after 125 years of operation. They are skillfully examined here and compared to the written record to create a moving—and devastating—group portrait of twentieth-century American psychiatric care.

    Married to a man for nearly a decade and mother to a toddler, Wizenberg tried to return to her life as she knew it, but something inside her had changed irredeemably. Instead, she would discover that the trajectory of our lives is rarely as smooth or as logical as we’d like to believe.   Like many of us, Wizenberg had long understood sexual orientation as a stable part of ourselves: we’re “born this way.” Suddenly she realized that her story was more complicated. Who was she, she wondered, if something at her very core could change so radically? The Fixed Stars is a taut, electrifying memoir exploring timely and timeless questions about desire, identity, and the limits and possibilities of family. In honest and searing prose, Wizenberg forges a new path: through the murk of separation and divorce, coming out to family and friends, learning to co-parent a young child, and realizing a new vision of love. The result is a frank and moving story about letting go of rigid definitions and ideals that no longer fit, and learning instead who we really are.

    When she was young, Lisa's father was a mythical figure who was rarely present in her life. As she grew older, her father took an interest in her, ushering her into a new world of mansions, vacations, and private schools. His attention was thrilling, but he could also be cold, critical and unpredictable. When her relationship with her mother grew strained in high school, Lisa decided to move in with her father, hoping he'd become the parent she'd always wanted him to be.Small Fry is Lisa Brennan-Jobs's poignant story of a childhood spent between two imperfect but extraordinary homes. Scrappy, wise, and funny, young Lisa is an unforgettable guide through her parents' fascinating and disparate worlds. Part portrait of a complex family, part love letter to California in the seventies and eighties, Small Fry is an enthralling book by an insightful new literary voice.