The Epigenetics Revolution


Nessa Carey - 2011
    The Human Genome Project finished sequencing human DNA. It seemed it was only a matter of time until we had all the answers to the secrets of life on this planet. The cutting-edge of biology, however, is telling us that we still don't even know all of the questions. How is it that, despite each cell in your body carrying exactly the same DNA, you don't have teeth growing out of your eyeballs or toenails on your liver? How is it that identical twins share exactly the same DNA and yet can exhibit dramatic differences in the way that they live and grow? It turns out that cells read the genetic code in DNA more like a script to be interpreted than a mould that replicates the same result each time. This is epigenetics and it's the fastest-moving field in biology today. The Epigenetics Revolution traces the thrilling path this discipline has taken over the last twenty years. Biologist Nessa Carey deftly explains such diverse phenomena as how queen bees and ants control their colonies, why tortoiseshell cats are always female, why some plants need a period of cold before they can flower, why we age, develop disease and become addicted to drugs, and much more. Most excitingly, Carey reveals the amazing possibilities for humankind that epigenetics offers for us all - and in the surprisingly near future.

Deep Nutrition: Why Your Genes Need Traditional Food


Catherine Shanahan - 2008
    The length of our limbs, the shape of our eyes, and the proper function of our organs are all gifts of our ancestor's collective culinary wisdom. Citing the foods of traditional cultures from the Ancient Egyptians and the Maasai to the Japanese and the French, the Shanahans identify four food categories all the world's healthiest diets have in common, the Four Pillars of World Cuisine. Using the latest research in physiology and genetics, Dr. Shanahan explains why your family's health depends on eating these foods. In a world of competing nutritional ideologies, Deep Nutrition gives us the full picture, empowering us to take control of our destiny in ways we might never have imagined.

The Edge of the World: A Cultural History of the North Sea and the Transformation of Europe


Michael Pye - 2014
    Now the critically acclaimed Michael Pye reveals the cultural transformation sparked by those men and women: the ideas, technology, science, law, and moral codes that helped create our modern world. This is the magnificent lost history of a thousand years. It was on the shores of the North Sea where experimental science was born, where women first had the right to choose whom they married; there was the beginning of contemporary business transactions and the advent of the printed book. In The Edge of the World, Michael Pye draws on an astounding breadth of original source material to illuminate this fascinating region during a pivotal era in world history.

The Doctors Blackwell: How Two Pioneering Sisters Brought Medicine to Women and Women to Medicine


Janice P. Nimura - 2021
    Though the world at first recoiled at the notion of a woman studying medicine, her intelligence and intensity ultimately won her the acceptance of the male medical establishment. In 1849, she became the first woman in America to receive an M.D. She was soon joined in her iconic achievement by her younger sister, Emily, who was actually the more brilliant physician.Exploring the sisters’ allies, enemies, and enduring partnership, Janice P. Nimura presents a story of trial and triumph. Together, the Blackwells founded the New York Infirmary for Indigent Women and Children, the first hospital staffed entirely by women. Both sisters were tenacious and visionary, but their convictions did not always align with the emergence of women’s rights—or with each other. From Bristol, Paris, and Edinburgh to the rising cities of antebellum America, this richly researched new biography celebrates two complicated pioneers who exploded the limits of possibility for women in medicine. As Elizabeth herself predicted, "a hundred years hence, women will not be what they are now."

Strange Medicine: A Shocking History of Real Medical Practices Through the Ages


Nathan Belofsky - 2013
    Medieval dentists burned candles in patients' mouths to kill invisible worms gnawing at their teeth. Renaissance physicians, by law, timed surgical procedures with the position of the stars, and instructed epileptics to collect fresh blood from the newly beheaded. Highlighting bad science, oafish behavior, and stomach-turning procedures that hurt more than helped, Strange Medicine presents extraordinary but true facts and an honor roll of doctors, scientists, and dreamers who gave a whole new meaning to clinical trials!

Dr. Mütter's Marvels: A True Tale of Intrigue and Innovation at the Dawn of Modern Medicine


Cristin O'Keefe Aptowicz - 2014
    This was the world of medicine when Thomas Dent Mütter began his trailblazing career as a plastic surgeon in Philadelphia during the middle of the nineteenth century.Although he died at just forty-eight, Mütter was an audacious medical innovator who pioneered the use of ether as anesthesia, the sterilization of surgical tools, and a compassion-based vision for helping the severely deformed, which clashed spectacularly with the sentiments of his time.   Brilliant, outspoken, and brazenly handsome, Mütter was flamboyant in every aspect of his life. He wore pink silk suits to perform surgery, added an umlaut to his last name just because he could, and amassed an immense collection of medical oddities that would later form the basis of Philadelphia’s Mütter Museum. Cristin O’Keefe Aptowicz chronicles how Mütter’s efforts helped establish Philadelphia as a global mecca for medical innovation—despite intense resistance from his numerous rivals.

The Heart Healers: The Misfits, Mavericks, and Rebels Who Created the Greatest Medical Breakthrough of Our Lives


James S. Forrester - 2015
    By the middle of the twentieth century, it was killing millions and, as with the Black Death centuries before, physicians stood helpless. Visionaries, though, had begun to make strides earlier. On September 7, 1895, Ludwig Rehn successfully sutured the heart of a living man with a knife wound to the chest for the first time. In 1929, Dr. Werner Forssman inserted a cardiac catheter in his own arm and forced the X-ray technician on duty to take a photo as he successfully threaded it down the vein into his own heart . . . and lived. And on June 6, 1944 D-Day another momentous event occurred far from the Normandy beaches: Dr. Dwight Harken sutured the shrapnel-injured heart of a young soldier and saved his life, and thus the term "cardiac surgeon" was born. In "The Heart Healers," James Forrester, MD, tells the story of these rebels and the risks they took with their own lives and the lives of others to heal the most elemental of human organs: the heart. The result is a compelling chronicle of a disease and its cure, a disease that is still with us, but one that is slowly being worn away by the "Heart Healers."

A History of Archaeological Thought


Bruce G. Trigger - 1989
    The development of archeological thought is analyzed by examining archeological history to determine to what extent its trends reflect archeologists' personal & collective interests.List of IllustrationsPrefaceThe relevance of archaeological history Classical archaeology & antiquarianismThe beginnings of scientific archaeologyThe imperial synthesis Culture-historical archaeologySoviet archaeology Functionalism in Western archaeology Neo-evolutionism & the new archaeology The explanation of diversity Archaeology & its social contextBibliographical EssayReferencesIndex

Paleofantasy: What Evolution Really Tells Us about Sex, Diet, and How We Live


Marlene Zuk - 2013
    Contrary to what the glossy magazines would have us believe, we do not enjoy potato chips because they crunch just like the insects our forebears snacked on. As Zuk argues, such beliefs incorrectly assume that we’re stuck—finished evolving—and have been for tens of thousands of years. She draws on fascinating evidence that examines everything from adults’ ability to drink milk to the texture of our ear wax to show that we’ve actually never stopped evolving. Our nostalgic visions of an ideal evolutionary past in which we ate, lived, and reproduced as we were “meant to” fail to recognize that we were never perfectly suited to our environment. Evolution is about change, and every organism is full of trade-offs.From debunking the caveman diet to unraveling gender stereotypes, Zuk gives an analysis of widespread paleofantasies and the scientific evidence that undermines them, all the while broadening our understanding of our origins and what they can really tell us about our present and our future.

The Scientific Revolution


Steven Shapin - 1996
    "Shapin's account is informed, nuanced, and articulated with clarity. . . . This is not to attack or devalue science but to reveal its richness as the human endeavor that it most surely is. . . .Shapin's book is an impressive achievement."—David C. Lindberg, Science"Shapin has used the crucial 17th century as a platform for presenting the power of science-studies approaches. At the same time, he has presented the period in fresh perspective."—Chronicle of Higher Education"Timely and highly readable . . . A book which every scientist curious about our predecessors should read."—Trevor Pinch, New Scientist"It's hard to believe that there could be a more accessible, informed or concise account of how it [the scientific revolution], and we have come to this. The Scientific Revolution should be a set text in all the disciplines. And in all the indisciplines, too."—Adam Phillips, London Review of Books"Shapin's treatise on the currents that engendered modern science is a combination of history and philosophy of science for the interested and educated layperson."—Publishers Weekly"Superlative, accessible, and engaging. . . . Absolute must-reading."—Robert S. Frey, Bridges"This vibrant historical exploration of the origins of modern science argues that in the 1600s science emerged from a variety of beliefs, practices, and influences. . . . This history reminds us that diversity is part of any intellectual endeavor."—Choice"Most readers will conclude that there was indeed something dramatic enough to be called the Scientific Revolution going on, and that this is an excellent book about it."—Anthony Gottlieb, The New York Times Book Review

To Explain the World: The Discovery of Modern Science


Steven Weinberg - 2015
    He shows that the scientists of ancient and medieval times not only did not understand what we understand about the world—they did not understand what there is to understand, or how to understand it. Yet over the centuries, through the struggle to solve such mysteries as the curious backward movement of the planets and the rise and fall of the tides, the modern discipline of science eventually emerged. Along the way, Weinberg examines historic clashes and collaborations between science and the competing spheres of religion, technology, poetry, mathematics, and philosophy.An illuminating exploration of the way we consider and analyze the world around us, To Explain the World is a sweeping, ambitious account of how difficult it was to discover the goals and methods of modern science, and the impact of this discovery on human knowledge and development.

Plague of Corruption: Restoring Faith in the Promise of Science


Judy Mikovits - 2020
    Judy Mikovits is a modern-day Rosalind Franklin, a brilliant researcher shaking up the old boys’ club of science with her groundbreaking discoveries. And like many women who have trespassed into the world of men, she uncovered decades-old secrets that many would prefer to stay buried. From her doctoral thesis, which changed the treatment of HIV-AIDS, saving the lives of millions, including basketball great Magic Johnson, to her spectacular discovery of a new family of human retroviruses, and her latest research which points to a new golden age of health, Dr. Mikovits has always been on the leading edge of science. With the brilliant wit one might expect if Erin Brockovich had a doctorate in molecular biology, Dr. Mikovits has seen the best and worst of science. When she was part of the research community that turned HIV-AIDS from a fatal disease into a manageable one, she saw science at its best. But when her investigations questioned whether the use of animal tissue in medical research were unleashing devastating plagues of chronic diseases, such as autism and chronic fatigue syndrome, she saw science at its worst. If her suspicions are correct, we are looking at a complete realignment of scientific practices, including how we study and treat human disease. Recounting her nearly four decades in science, including her collaboration of more than thirty-five years with Dr. Frank Ruscetti, one of the founders of the field of human retrovirology, this is a behind the scenes look at the issues and egos which will determine the future health of humanity.

Oxford Handbook of Clinical Medicine


Murray Longmore - 2002
    This edition retains the essence of the original, but has been updated with new features and integrated colour illustrations.

Deadly Outbreaks: How Medical Detectives Save Lives Threatened by Killer Pandemics, Exotic Viruses, and Drug-Resistant Parasites


Alexandra M. Levitt - 2013
    Vaccines and antibiotics, the mainstays of modern medicine, have not been able to conquer infectious microbes because of their amazing ability to adapt, evolve, and spread to new places. Terrorism aside, one of the greatest dangers from infectious disease we face today is from a massive outbreak of drug-resistant microbes.Deadly Outbreaks recounts the scientific adventures of a special group of intrepid individuals who investigate these outbreaks around the world and figure out how to stop them. Part homicide detective, part physician, these medical investigators must view the problem from every angle, exhausting every possible source of contamination. Any data gathered in the field must be stripped of human sorrows and carefully analyzed into hard statistics.Author Dr. Alexandra Levitt is an expert on emerging diseases and other public health threats. Here she shares insider accounts she’s collected that go behind the alarming headlines we’ve seen in the media: mysterious food poisonings, unexplained deaths at a children’s hospital, a strange neurologic disease afflicting slaughterhouse workers, flocks of birds dropping dead out of the sky, and drug-resistant malaria running rampant in a refugee camp. Meet the resourceful investigators—doctors, veterinarians, and research scientists—and discover the truth behind these cases and more.

Survival of the Sickest: A Medical Maverick Discovers Why We Need Disease


Sharon Moalem - 2007
    Sharon Moalem turns our current understanding of illness on its head and challenges us to fundamentally change the way we think about our bodies, our health, and our relationship to just about every other living thing on earth, from plants and animals to insects and bacteria.Through a fresh and engaging examination of our evolutionary history, Dr. Moalem reveals how many of the conditions that are diseases today actually gave our ancestors a leg up in the survival sweepstakes. When the option is a long life with a disease or a short one without it, evolution opts for disease almost every time.Everything from the climate our ancestors lived in to the crops they planted and ate to their beverage of choice can be seen in our genetic inheritance. But Survival of the Sickest doesn't stop there. It goes on to demonstrate just how little modern medicine really understands about human health, and offers a new way of thinking that can help all of us live longer, healthier lives..