But, despite appearances, these are not dogs—they are foxes. They are the result of the most astonishing experiment in breeding ever undertaken—imagine speeding up thousands of years of evolution into a few decades. In 1959, biologists Dmitri Belyaev and Lyudmila Trut set out to do just that, by starting with a few dozen silver foxes from fox farms in the USSR and attempting to recreate the evolution of wolves into dogs in real time in order to witness the process of domestication. This is the extraordinary, untold story of this remarkable undertaking. Most accounts of the natural evolution of wolves place it over a span of about 15,000 years, but within a decade, Belyaev and Trut’s fox breeding experiments had resulted in puppy-like foxes with floppy ears, piebald spots, and curly tails. Along with these physical changes came genetic and behavioral changes, as well. The foxes were bred using selection criteria for tameness, and with each generation, they became increasingly interested in human companionship. Trut has been there the whole time, and has been the lead scientist on this work since Belyaev’s death in 1985, and with Lee Dugatkin, biologist and science writer, she tells the story of the adventure, science, politics, and love behind it all.  In How to Tame a Fox, Dugatkin and Trut take us inside this path-breaking experiment in the midst of the brutal winters of Siberia to reveal how scientific history is made and continues to be made today. To date, fifty-six generations of foxes have been domesticated, and we continue to learn significant lessons from them about the genetic and behavioral evolution of domesticated animals. How to Tame a Fox offers an incredible tale of scientists at work, while also celebrating the deep attachments that have brought humans and animals together throughout time.

    It has dealt with issues of religious freedom, patriotism, terrorism, genetic engineering, and the ultimate science fiction question: what does it mean to be human? While the re-imagined BSG may not be packed with cool techie tools (the bad guys don't even have laser guns for frak's sake!), this book shows that the science in the series has a lot to say about the use of science and technology in our lives today.What are the principles behind artificial gravity and sublight propulsion? Are Cylons men or machines? How are humanoid Cylons able to interface with computers? By tackling these and other intriguing questions, The Science of Battlestar Galactica takes us billions of miles away from Earth so that we can turn around and see ourselves from a different perspective.Tackles fans' most pressing BSG questions, from how an FTL drive might work to how the 12 colonies of Kobol could co-exist to the principles behind Gaius Baltar's Cylon-detectorFeatures behind-the-scenes anecdotes, quotes from the BSG Series Bible, and over 60 photosIncludes a foreword by BSG co-executive producer, Jane Espenson, and an afterword by actor, Richard Hatch, who played Tom Zarek in the reimagined series and Captain Apollo in the classic seriesCo-written by BSG's scientific advisor and a Wired contributing editorPacked with must-know details and scientific background, this thought-provoking book will help you see Battlestar Galactica as never before.

    

    Nearly a half-century after Neil Armstrong walked on the moon, these Space Barons-most notably Elon Musk and Jeff Bezos, along with Richard Branson and Paul Allen-are using Silicon Valley-style innovation to dramatically lower the cost of space travel, and send humans even further than NASA has gone. These entrepreneurs have founded some of the biggest brands in the world-Amazon, Microsoft, Virgin, Tesla, PayPal-and upended industry after industry. Now they are pursuing the biggest disruption of all: space. Based on years of reporting and exclusive interviews with all four billionaires, this authoritative account is a dramatic tale of risk and high adventure, the birth of a new Space Age, fueled by some of the world's richest men as they struggle to end governments' monopoly on the cosmos. The Space Barons is also a story of rivalry-hard-charging startups warring with established contractors, and the personal clashes of the leaders of this new space movement, particularly Musk and Bezos, as they aim for the moon and Mars and beyond.

    Stargazing is a pursuit that continues to fascinate us: from Copernicus to Carl Sagan, astronomers throughout history have spent their lives trying to answer the biggest questions in the universe. Now, award-winning astronomer Emily Levesque shares the stories of modern-day stargazers, the people willing to adventure across high mountaintops and to some of the most remote corners of the planet, all in the name of science.From the lonely quiet of midnight stargazing to tall tales of wild bears loose in the observatory, The Last Stargazers is a love letter to astronomy and an affirmation of the crucial role that humans can and must play in the future of scientific discovery.In this sweeping work of narrative science, Levesque shows how astronomers in this scrappy and evolving field are going beyond the machines to infuse creativity and passion into the stars and inspires us all to peer skyward in pursuit of the universe's secrets.

    In Dark Banquet, zoologist Bill Schutt takes readers on an entertaining voyage into the world of some of nature’s strangest creatures—the sanguivores. Using a sharp eye and mordant wit, Schutt makes a remarkably persuasive case that vampire bats, leeches, ticks, bed bugs, and other vampires are as deserving of our curiosity as warmer and fuzzier species are—and that many of them are even ­worthy of conservation.Schutt takes us from rural Trinidad to the jungles of Brazil to learn about some of the most reviled, misunderstood, and marvelously evolved animals on our planet: vampire bats. Only recently has fact begun to disentangle itself from fiction concerning these remarkable animals, and Schutt delves into the myths and misconceptions surrounding them. Examining the substance that sustains nature’s vampires, Schutt reveals just how little we actually knew about blood until well into the twentieth century. We revisit George Washington on his deathbed to learn how ideas about blood and the supposedly therapeutic value of bloodletting, first devised by the ancient Egyptians and Greeks, survived into relatively modern times. Schutt also tracks the history of medicinal leech use. Once employed by the tens of millions to drain perceived excesses of blood, today the market for these ancient creatures is booming once again—but for very different reasons.Among the other blood feeders we meet in these pages are bed bugs, or “ninja insects,” which are making a creepy resurgence in posh hotels and well-kept homes near you. In addition, Dark Banquet details our dangerous and sometimes deadly encounters with ticks, chiggers, and mites (the ­latter implicated in Colony Collapse Disorder—currently devastating honey bees worldwide). Then there are the truly weird—vampire finches. And if you thought piranha were scary, some people believe that the candiru (or willy fish) is the best reason to avoid swimming in the Amazon.Enlightening, alarming, and appealing to our delight in the bizarre, Dark Banquet peers into a part of the natural world to which we are, through our blood, inextricably linked.From the Hardcover edition.

    These “psychosurgeons,” as they called themselves, occupied a gray zone between medical research and medical practice, and ended up subjecting untold numbers of people to the types of surgical experiments once limited to chimpanzees.The most important test subject to emerge from this largely untold chapter in American history was a twenty-seven-year-old factory worker named Henry Molaison. In 1953, Henry—who suffered from severe epilepsy—received a radical new version of the lobotomy, one that targeted the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry left the operating room profoundly amnesic, unable to create new long-term memories. Over the next sixty years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.Luke Dittrich uses the case of Patient H.M. as a starting point for a kaleidoscopic journey, one that moves from the first recorded brain surgeries in ancient Egypt to the cutting-edge laboratories of MIT. He takes readers inside the old asylums and operating theaters where psychosurgeons conducted their human experiments, and behind the scenes of a bitter custody battle over the ownership of the most important brain in the world. Throughout, Dittrich delves into the enduring mysteries of the mind while exposing troubling stories of just how far we’ve gone in our pursuit of knowledge. It is also, at times, a deeply personal journey. Dittrich’s grandfather was the brilliant, morally complex surgeon who operated on Molaison—and thousands of other patients. The author’s investigation into the dark roots of modern memory science ultimately forces him to confront unsettling secrets in his own family history, and to reveal the tragedy that fueled his grandfather’s relentless experimentation—experimentation that would revolutionize our understanding of ourselves.Patient H.M. combines the best of biography, memoir, and science journalism to create a haunting, endlessly fascinating story, one that reveals the wondrous and devastating things that can happen when hubris, ambition, and human imperfection collide.

    Krause is a pioneer in the revolutionary new science of archaeogenetics, archaeology augmented by revolutionary DNA sequencing technology, which has allowed scientists to uncover a new version of human history reaching back more than 100,000 years. Using this technology to re-examine human bones from the distant past, Krause has been able to map not only the genetic profiles of the dead, but also their ancient journeys.In this concise narrative he tells us their long-forgotten stories of migration and intersection. It's well known that many human populations carry genetic material from Neanderthals; but, as Krause and his colleagues discovered, we also share DNA with a newly uncovered human form, the Denisovans. We know now that a wave of farmers from Anatolia migrated into Europe 8,000 years ago, essentially displacing the dark-skinned, blue-eyed hunter-gatherers who preceded them. The farmer DNA is one of the core genetic components of contemporary Europeans and European Americans. Though the first people to cross into North and South America have long been assumed to be primarily of East Asian descent, we now know that they also share DNA with contemporary Europeans and European Americans. Genetics has an unfortunate history of smuggling in racist ideologies, but our most cutting-edge science tells us that genetic categories in no way reflect national borders.Krause vividly introduces us to prehistoric cultures such as the Aurignacians, innovative artisans who carved animals, people, and even flutes from bird bones more than 40,000 years ago; the Varna, who buried their loved ones with gold long before the Pharaohs of Egypt; and the Gravettians, big-game hunters who were Europe's most successful early settlers until they perished in the ice age. This informed retelling of the human epic confirms that immigration and genetic mingling have always defined our species and that who we are is a question of culture not genetics.

    This trusted classic delivers comprehensive coverage of the field's must-know basic science and clinical topics in a clear, easy-to-understand presentation. Indispensable for coursework, exam review, and as a clinical refresher, this trusted text has been extensively updated to reflect the latest research and developments.Here's why Clinical Anesthesiology is the best anesthesiology resource:NEW full-color presentationNEW chapters on the most pertinent topics in anesthesiology, including anesthesia outside of the operating room and a revamped peripheral nerve blocks chapter that details ultrasound-guided regional anesthesiaUp-to-date discussion of all relevant areas within anesthesiology, including equipment, pharmacology, regional anesthesia, pathophysiology, pain management, and critical careCase discussions promote application of the concepts to real-world practiceNumerous tables and figures encapsulate important information and facilitate memorization

    Just think about different behaviors you see at a dog park: We have a good understanding of what it means when dogs wag their tails—but what about when they sniff and roll on a stinky spot? Why do they play tug-of-war with one dog, while showing their bellies to another? Why are some dogs shy, while others are bold? What goes on in dogs’ heads and hearts—and how much can we know and understand?  Canine Confidential has the answers. Written by award-winning scientist—and lifelong dog lover—Marc Bekoff, it not only brilliantly opens up the world of dog behavior, but also helps us understand how we can make our dogs’ lives the best they can possibly be.  Rooted in the most up-to-date science on cognition and emotion—fields that have exploded in recent years—Canine Confidential is a wonderfully accessible treasure trove of new information and myth-busting. Peeing, we learn, isn’t always marking; grass-eating isn’t always an attempt to trigger vomiting; it’s okay to hug a dog—on their terms; and so much more. There’s still much we don’t know, but at the core of the book is the certainty that dogs do have deep emotional lives, and that as their companions we must try to make those lives as rich and fulfilling as possible. It’s also clear that we must look at dogs as unique individuals and refrain from talking about “the dog.”   Bekoff also considers the practical importance of knowing details about dog behavior. He advocates strongly for positive training—there’s no need to dominate or shame dogs or to make them live in fear—and the detailed information contained in Canine Confidential has a good deal of significance for dog trainers and teachers. He also suggests that trainers should watch and study dogs in various contexts outside of those in which they are dealing with clients, canine and human, with specific needs.    There’s nothing in the world as heartwarming as being greeted by your dog at the end of the workday. Read Canine Confidential, and you’ll be on the road to making your shared lives as happy, healthy, and rewarding as they can possibly be.

    In the great halls of science, dogma holds that Darwin's theory of natural selection explains every branch on the tree of life: which species thrive, which wither away to extinction, and what features each evolves. But can adaptation by natural selection really account for everything we see in nature? Yale University ornithologist Richard Prum--reviving Darwin's own views--thinks not. Deep in tropical jungles around the world are birds with a dizzying array of appearances and mating displays: Club-winged Manakins who sing with their wings, Great Argus Pheasants who dazzle prospective mates with a four-foot-wide cone of feathers covered in golden 3D spheres, Red-capped Manakins who moonwalk. In thirty years of fieldwork, Prum has seen numerous display traits that seem disconnected from, if not outright contrary to, selection for individual survival. To explain this, he dusts off Darwin's long-neglected theory of sexual selection in which the act of choosing a mate for purely aesthetic reasons--for the mere pleasure of it--is an independent engine of evolutionary change. Mate choice can drive ornamental traits from the constraints of adaptive evolution, allowing them to grow ever more elaborate. It also sets the stakes for sexual conflict, in which the sexual autonomy of the female evolves in response to male sexual control. Most crucially, this framework provides important insights into the evolution of human sexuality, particularly the ways in which female preferences have changed male bodies, and even maleness itself, through evolutionary time. The Evolution of Beauty presents a unique scientific vision for how nature's splendor contributes to a more complete understanding of evolution and of ourselves.

    Rochman takes an authoritative look at the latest hot-button issues in the world of pre- and postnatal testing and tells the stories of women and men struggling to understand the variety of tests and grappling with their results—revelations that are sometimes joyous, sometimes heartbreaking, and often profound.Propelled by human narratives and meticulously reported, The Gene Machine introduces us to scientists working to unlock the secrets of the human genome; gene counselors and spiritual advisers helping parents manage this complex new reality; and, of course, parents themselves, including the author, who glimpse the genetic futures of their children. The Gene Machine is both a scientific road map and a meditation on our power to shape the future, one that gets to the very core of what it means to be human.

    Its starting point is the annual Turing Test, which pits artificial intelligence programs against people to determine if computers can “think.”Named for computer pioneer Alan Turing, the Tur­ing Test convenes a panel of judges who pose questions—ranging anywhere from celebrity gossip to moral conundrums—to hidden contestants in an attempt to discern which is human and which is a computer. The machine that most often fools the panel wins the Most Human Computer Award. But there is also a prize, bizarre and intriguing, for the Most Human Human.In 2008, the top AI program came short of passing the Turing Test by just one astonishing vote. In 2009, Brian Christian was chosen to participate, and he set out to make sure Homo sapiens would prevail.The author’s quest to be deemed more human than a com­puter opens a window onto our own nature. Interweaving modern phenomena like customer service “chatbots” and men using programmed dialogue to pick up women in bars with insights from fields as diverse as chess, psychiatry, and the law, Brian Christian examines the philosophical, bio­logical, and moral issues raised by the Turing Test.One central definition of human has been “a being that could reason.” If computers can reason, what does that mean for the special place we reserve for humanity?

    Falling apart and bowing down to the miseries of a broken family and a daunting past, at 24, they decided to move on. But life pulled out one trick after another to bring them back to each other and give one last chance to do what they couldn't do in the past twelve years. A choice had to be made and there was no going back. Could they learn from the echoing footsteps of their parents and speak their heart out or the fear of saying the unsaid killed it once again for them? Did their time to fall in love come, or like always, they met, greeted and departed to part forever?

    But which one? And how?Over the past fifty years, more than three hundred infectious diseases have either newly emerged or reemerged, appearing in territories where they’ve never been seen before. Ninety percent of epidemiologists expect that one of them will cause a deadly pandemic sometime in the next two generations. It could be Ebola, avian flu, a drug-resistant superbug, or something completely new. While we can’t know which pathogen will cause the next pandemic, by unraveling the story of how pathogens have caused pandemics in the past, we can make predictions about the future. In Pandemic: Tracking Contagions, from Cholera to Ebola and Beyond, the prizewinning journalist Sonia Shah—whose book on malaria, The Fever, was called a “tour-de-force history” (The New York Times) and “revelatory” (The New Republic)—interweaves history, original reportage, and personal narrative to explore the origins of contagions, drawing parallels between cholera, one of history’s most deadly and disruptive pandemic-causing pathogens, and the new diseases that stalk humankind today.To reveal how a new pandemic might develop, Sonia Shah tracks each stage of cholera’s dramatic journey, from its emergence in the South Asian hinterlands as a harmless microbe to its rapid dispersal across the nineteenth-century world, all the way to its latest beachhead in Haiti. Along the way she reports on the pathogens now following in cholera’s footsteps, from the MRSA bacterium that besieges her own family to the never-before-seen killers coming out of China’s wet markets, the surgical wards of New Delhi, and the suburban backyards of the East Coast.By delving into the convoluted science, strange politics, and checkered history of one of the world’s deadliest diseases, Pandemic reveals what the next global contagion might look like— and what we can do to prevent it.