Leonard Mlodinow takes us on a passionate and inspiring tour through the exciting history of human progress and the key events in the development of science. In the process, he presents a fascinating new look at the unique characteristics of our species and our society that helped propel us from stone tools to written language and through the birth of chemistry, biology, and modern physics to today’s technological world.   Along the way he explores the cultural conditions that influenced scientific thought through the ages and the colorful personalities of some of the great philosophers, scientists, and thinkers: Galileo, who preferred painting and poetry to medicine and dropped out of university; Isaac Newton, who stuck needlelike bodkins into his eyes to better understand changes in light and color; and Antoine Lavoisier, who drank nothing but milk for two weeks to examine its effects on his body. Charles Darwin, Albert Einstein, Werner Heisenberg, and many lesser-known but equally brilliant minds also populate these pages, each of their stories showing how much of human achievement can be attributed to the stubborn pursuit of simple questions (why? how?), bravely asked.  The Upright Thinkers is a book for science lovers and for anyone interested in creative thinking and in our ongoing quest to understand our world. At once deeply informed, accessible, and infused with the author’s trademark wit, this insightful work is a stunning tribute to humanity’s intellectual curiosity.  (With black-and-white illustrations throughout.)

    How we address it in the next thirty years will determine the kind of world we will live in and will bequeath to our children and to theirs.In The Future We Choose, Christiana Figueres and Tom Rivett-Carnac--who led negotiations for the United Nations during the historic Paris Agreement of 2015--have written a cautionary but optimistic book about the world's changing climate and the fate of humanity.The authors outline two possible scenarios for our planet. In one, they describe what life on Earth will be like by 2050 if we fail to meet the Paris climate targets. In the other, they lay out what it will be like to live in a carbon neutral, regenerative world. They argue for confronting the climate crisis head-on, with determination and optimism. The Future We Choose presents our options and tells us what governments, corporations, and each of us can and must do to fend off disaster.

    Yet under the right circumstances, it is the single most dangerous germ on the planet.Orent reveals how Soviet scientists created genetically-altered forms of this terrible affliction, knowing exactly how to convert plague into a deadly weapon.She shows how scientists are still unable to defend against it, and how plague could be visited upon humanity again.

    Full of extraordinary facts and astonishing stories, The Body: A Guide for Occupants is a brilliant, often very funny attempt to understand the miracle of our physical and neurological make up.A wonderful successor to A Short History of Nearly Everything, this book will have you marvelling at the form you occupy, and celebrating the genius of your existence, time and time again.

    For two decades, historian Alice Dreger has led a life of extraordinary engagement, combining activist service to victims of unethical medical research with defense of scientists whose work has outraged identity politics activists. With spirit and wit, Dreger offers in Galileo’s Middle Finger an unforgettable vision of the importance of rigorous truth seeking in today’s America, where both the free press and free scholarly inquiry struggle under dire economic and political threats.This illuminating chronicle begins with Dreger’s own research into the treatment of people born intersex (once called hermaphrodites). Realization of the shocking surgical and ethical abuses conducted in the name of “normalizing” intersex children’s gender identities moved Dreger to become an internationally recognized patient rights’ activist. But even as the intersex rights movement succeeded, Dreger began to realize how some fellow progressive activists were employing lies and personal attacks to silence scientists whose data revealed uncomfortable truths about humans. In researching one such case, Dreger suddenly became the target of just these kinds of attacks.Troubled, she decided to try to understand more—to travel the country to ferret out the truth behind various controversies, to obtain a global view of the nature and costs of these battles. Galileo’s Middle Finger describes Dreger’s long and harrowing journeys between the two camps for which she felt equal empathy: social justice activists determined to win and researchers determined to put hard truths before comfort. Ultimately what emerges is a lesson about the intertwining of justice and of truth—and a lesson of the importance of responsible scholars and journalists to our fragile democracy.

    Loyal, obedient, and affectionate, they are truly “man’s best friend.” But do dogs love us the way we love them? Emory University neuroscientist Gregory Berns had spent decades using MRI imaging technology to study how the human brain works, but a different question still nagged at him: What is my dog thinking?   After his family adopted Callie, a shy, skinny terrier mix, Berns decided that there was only one way to answer that question—use an MRI machine to scan the dog’s brain. His colleagues dismissed the idea. Everyone knew that dogs needed to be restrained or sedated for MRI scans. But if the military could train dogs to operate calmly in some of the most challenging environments, surely there must be a way to train dogs to sit in an MRI scanner.   With this radical conviction, Berns and his dog would embark on a remarkable journey and be the first to glimpse the inner workings of the canine brain. Painstakingly, the two worked together to overcome the many technical, legal, and behavioral hurdles. Berns’s research offers surprising results on how dogs empathize with human emotions, how they love us, and why dogs and humans share one of the most remarkable friendships in the animal kingdom.   How Dogs Love Us answers the age-old question of dog lovers everywhere and offers profound new evidence that dogs should be treated as we would treat our best human friends: with love, respect, and appreciation for their social and emotional intelligence.

    In The Woman with a Worm in Her Head, Dr. Pamela Nagami reveals-through real-life cases-the sobering facts about some of the world's most horrific diseases: the warning signs, the consequences, treatments, and most compellingly, what it feels like to make medical and ethical decisions that can mean the difference between life and death.Unfailingly precise, calmly instructive, and absolutely engrossing, The Woman with the Worm in Her Head offers both useful information and enjoyable reading.

    He visits Norwegian megafarms that use genetic techniques once pioneered on sheep to grow millions of pounds of salmon a year. He travels to the ancestral river of the Yupik Eskimos to see the only Fair Trade–certified fishing company in the world. He makes clear how PCBs and mercury find their way into seafood; discovers how Mediterranean sea bass went global; challenges the author of Cod to taste the difference between a farmed and a wild cod; and almost sinks to the bottom of the South Pacific while searching for an alternative to endangered bluefin tuna.Fish, Greenberg reveals, are the last truly wild food — for now. By examining the forces that get fish to our dinner tables, he shows how we can start to heal the oceans and fight for a world where healthy and sustainable seafood is the rule rather than the exception.

    We have a consumption crisis. And this book, which takes aim at cherished assumptions regarding energy, offers refreshingly straight talk about what’s wrong with the way we think and talk about the problem. Though we generally believe we can solve environmental problems with more energy—more solar cells, wind turbines, and biofuels—alternative technologies come with their own side effects and limitations. How, for instance, do solar cells cause harm? Why can’t engineers solve wind power’s biggest obstacle? Why won’t contraception solve the problem of overpopulation lying at the heart of our concerns about energy, and what will? This practical, environmentally informed, and lucid book persuasively argues for a change of perspective. If consumption is the problem, as Ozzie Zehner suggests, then we need to shift our focus from suspect alternative energies to improving social and political fundamentals: walkable communities, improved consumption, enlightened governance, and, most notably, women’s rights. The dozens of first steps he offers are surprisingly straightforward. For instance, he introduces a simple sticker that promises a greater impact than all of the nation’s solar cells. He uncovers why carbon taxes won’t solve our energy challenges (and presents two taxes that could). Finally, he explores how future environmentalists will focus on similarly fresh alternatives that are affordable, clean, and can actually improve our well-being. Watch a book trailer.

    We will always have exactly as much water on Earth as we have ever had. Water cannot be destroyed, and it can always be made clean enough for drinking again. In fact, water can be made so clean that it actually becomes toxic. As Charles Fishman brings vibrantly to life in this delightful narrative excursion, water runs our world in a host of awe-inspiring ways, which is both the promise and the peril of our unexplored connections to it. Taking listeners from the wet moons of Saturn to the water-obsessed hotels of Las Vegas, and from a rice farm in the Australian outback to a glimpse into giant vats of soup at Campbell's largest factory, he reveals that our relationship to water is conflicted and irrational, neglected and mismanaged. Whether we will face a water scarcity crisis has little to do with water and everything to do with how we think about water-how we use it, connect with it, and understand it.Portraying and explaining both the dangers-in 2008, Atlanta came just ninety days from running completely out of drinking water-and the opportunities, such as advances in rainwater harvesting and businesses that are making huge breakthroughs in water productivity, The Big Thirst will forever change the way we think about water, our crucial relationship to it, and the creativity we can bring to ensuring we always have plenty of it.

    The first epidemic to emerge in the era of climate change, the disease infects half a million people in the US and Europe each year, and untold multitudes in Canada, China, Russia, and Australia. Mary Beth Pfeiffer shows how we have contributed to this growing menace, and how modern medicine has underestimated its danger. She tells the heart-rending stories of families destroyed by a single tick bite, of children disabled, and of one woman’s tragic choice after an exhaustive search for a cure. Pfeiffer also warns of the emergence of other tick-borne illnesses that make Lyme more difficult to treat and pose their own grave risks. Lyme is an impeccably researched account of an enigmatic disease, making a powerful case for action to fight ticks, heal patients, and recognize humanity’s role in a modern scourge.

    They may not be printed in the menu, but many are in your food.These are a few of the literally millions of pounds of approved synthetic substances dumped into the environment every day, not just in the US but around the world. They seep into our water supply, are carried thousands of miles by wind and rain from the site of application, remain potent long after they are deposited, and constitute, in the words of one scientist, “biologic death bombs with a delayed time fuse and which may prove to be, in the long run, as dangerous to the existence of mankind as the arsenal of atom bombs.” All of these poisons are sanctioned--or in some cases, ignored--by the EPA.For twenty-five years E.G. Vallianatos saw the EPA from the inside, with rising dismay over how pressure from politicians and threats from huge corporations were turning it from the public's watchdog into a "polluter's protection agency." Based on his own experience, the testimony of colleagues, and hundreds of documents Vallianatos collected inside the EPA, Poison Spring reveals how the agency has continually reinforced the chemical-industrial complex.Writing with acclaimed environmental journalist McKay Jenkins, E.G. Vallianatos provides a devastating exposé of how the agency created to protect Americans and our environment has betrayed its mission. Half a century after after Rachel Carson's Silent Spring awakened us to the dangers of pesticides, we are poisoning our lands and waters with more toxic chemicals than ever.

    As the mosquito transformed the landscapes of civilization, humans were unwittingly required to respond to its piercing impact and universal projection of power.The mosquito has determined the fates of empires and nations, razed and crippled economies, and decided the outcome of pivotal wars, killing nearly half of humanity along the way. She (only females bite) has dispatched an estimated 52 billion people from a total of 108 billion throughout our relatively brief existence. As the greatest purveyor of extermination we have ever known, she has played a greater role in shaping our human story than any other living thing with which we share our global village.Imagine for a moment a world without deadly mosquitoes, or any mosquitoes, for that matter? Our history and the world we know, or think we know, would be completely unrecognizable.Driven by surprising insights and fast-paced storytelling, The Mosquito is the extraordinary untold story of the mosquito's reign through human history and her indelible impact on our modern world order.

    Making use of remarkable scientific discoveries that transform our understanding of how natural systems work, George Monbiot explores a new, positive environmentalism that shows how damaged ecosystems on land and at sea can be restored, and how this restoration can revitalize and enrich our lives. Challenging what he calls his “ecological boredom,” Monbiot weaves together a beautiful and riveting tale of wild places, wildlife, and wild people. Roaming the hills of Britain and the forests of Europe, kayaking off the coast of Wales with dolphins and seabirds, he seeks out the places that still possess something of the untamed spirit he would like to resurrect.He meets people trying to restore lost forests and bring back missing species—such as wolves, lynx, wolverines, wild boar, and gray whales—and explores astonishing evidence that certain species, not just humans, have the power to shape the physical landscape. This process of rewilding, Monbiot argues, offers an alternative to a silent spring: the chance of a raucous summer in which ecological processes resume and humans draw closer to the natural world.

    The word conjures up images of horrific diseases sweeping the globe and killing everyone in their path. But such highly lethal illnesses almost never create pandemics. The reality is deadly serious but far more subtle.In Pandemics: What Everyone Needs to Know�, Peter Doherty, who won the Nobel Prize for his work on how the immune system recognizes virus-infected cells, offers an essential guide to one of the truly life-or-death issues of our age. In concise, question-and-answer format, he explains the causes of pandemics, how they can be counteracted with vaccines and drugs, and how we can better prepare for them in the future. Doherty notes that the term "pandemic" refers not to a disease's severity but to its ability to spread rapidly over a wide geographical area. Extremely lethal pathogens are usually quickly identified and confined. Nevertheless, the rise of high-speed transportation networks and the globalization of trade and travel have radically accelerated the spread of diseases. A traveler from Africa arrived in New York in 1999 carrying the West Nile virus; one mosquito bite later, it was loose in the ecosystem. Doherty explains how the main threat of a pandemic comes from respiratory viruses, such as influenza and SARS, which disseminate with incredible speed through air travel. The climate disruptions of global warming, rising population density, and growing antibiotic resistance all complicate efforts to control pandemics. But Doherty stresses that pandemics can be fought effectively. Often simple health practices, especially in hospitals, can help enormously. And research into the animal reservoirs of pathogens, from SARS in bats to HIV in chimpanzees, show promise for our prevention efforts.Calm, clear, and authoritative, Peter Doherty's Pandemics is one of the most critically important additions to the What Everyone Needs to Know� series.What Everyone Needs to Know� is a registered trademark of Oxford University Press.