As recently as 1918, a pandemic of influenza claimed over 50 million lives worldwide. The advent of drugs and vaccines led to an era of hope when we thought our battles with infectious disease were won, but our optimism has been eroded by the recognition that many pathogens have the capacity to transform themselves and escape our efforts to eradicate them. Are we now facing an inevitable repeat of a calamity such as the 1918 influenza pandemic or the Black Death? Can we anticipate and thwart such an event, or are we wilfully creating the conditions that would promote the emergence of new and highly virulent human infectious disease?Sunetra Gupta is Professor of Theoretical Epidemiology at the University of Oxford specialising in infectious diseases. She holds a bachelor's degree from Princeton University and a Ph.D. from the University of London. She has been awarded the Scientific Medal by the Zoological Society of London and the Royal Society Rosalind Franklin Award for her scientific research. She is also a novelist whose books have been awarded the Sahitya Akademi Award, the Southern Arts Literature Prize, shortlisted for the Crossword Award, and longlisted for the DSC and Orange Prizes.

    Now you can become part of the movement - and together, we can make history.It's time. This is our last chance to do anything about the global climate and ecological emergency. Our last chance to save the world as we know it.Now or never, we need to be radical. We need to rise up. And we need to rebel.Extinction Rebellion is a global activist movement of ordinary people, demanding action from Governments. This is a book of truth and action. It has facts to arm you, stories to empower you, pages to fill in and pages to rip out, alongside instructions on how to rebel - from organising a roadblock to facing arrest.By the time you finish this book you will have become an Extinction Rebellion activist. Act now before it's too late.

    In Pandora’s DNA, Stark uses her family’s experience to frame a larger story about the so-called breast cancer genes, exploring the morass of legal quandaries, scientific developments, medical breakthroughs, and ethical concerns that surround the BRCA mutations, from the troubling history of prophylactic surgery and the storied origins of the boob job to the landmark lawsuit against Myriad Genetics, which held patents on the BRCA genes every human carries in their body until the Supreme Court overturned them in 2013. Although a genetic test for cancer risk may sound like the height of scientific development, the treatment remains crude and barbaric. Through her own experience, Stark shows what it’s like to live in a brave new world where gazing into a crystal ball of genetics has many unintended consequences.

    It is the repository of our deepest religious andartistic impulses, the organ whose steady functioning is understood, both literally and symbolically, asthe very life force itself. The Sublime Engine explores the profound sense of awe every person feels when they ponder the miracle encased within the ribs. In this lyrical history, a critically acclaimed novelist and a leading cardiologist—who happen to be brothers— draw upon history, science, religion, popular culture, and literature to illuminate all of the heart’s physical and figurative chambers. Divided into six sections, The Sublime Engine traces the heart’s sway over the human imagination from the time of the Egyptians and ancient Greece, through the Middle Ages and Renaissance, up to the modern era and beyond. More than just a work of scientific or cultural history, it is a biography of the single most important symbol of our humanity. Erudite, witty, and unexpected, The Sublime Engine makes the heart leap off the page.

    Thanks to the introduction of free-roaming cattle, ponies, pigs and deer – proxies of the large animals that once roamed Britain – the 3,500 acre project has seen extraordinary increases in wildlife numbers and diversity in little over a decade.Once-common species, including turtle doves, nightingales, peregrine falcons, lesser spotted woodpeckers and purple emperor butterflies, are now breeding at Knepp, and populations of other species are rocketing. The Burrells’ degraded agricultural land has become a functioning ecosystem again, heaving with life – all by itself.This recovery has taken place against a backdrop of catastrophic loss elsewhere. According to the 2016 ‘State of Nature’ report, the UK is ranked 29th in the world for biodiversity loss: 56% of species in the UK are in decline and 15% are threatened with extinction. We are living in a desert, compared with our gloriously wild past.In Wilding, Isabella Tree tells the story of the ‘Knepp experiment’ and what it reveals of the ways in which we might regain that wilder, richer country. It shows how rewilding works across Europe; that it has multiple benefits for the land; that it can generate economic activity and employment; how it can benefit both nature and us – and that all of this can happen astonishingly quickly. Part gripping memoir, part fascinating account of the ecology of our countryside, Wilding is, above all, an inspiring story of hope.

    In Never Home Alone, biologist Rob Dunn introduces us to the nearly 200,000 species living with us in our own homes, from the Egyptian meal moths in our cupboards and camel crickets in our basements to the lactobacillus lounging on our kitchen counters. You are not alone. Yet, as we obsess over sterilizing our homes and separating our spaces from nature, we are unwittingly cultivating an entirely new playground for evolution. These changes are reshaping the organisms that live with us -- prompting some to become more dangerous, while undermining those species that benefit our bodies or help us keep more threatening organisms at bay. No one who reads this engrossing, revelatory book will look at their homes in the same way again.

    When an epidemic hits, the EIS will be there to crack the case, however mysterious or deadly, saving countless lives in the process. Over the years they have successfully battled polio, cholera, and smallpox, to name a few, and in recent years have turned to the epidemics killing us now--smoking, obesity, and gun violence among them.The successful EIS model has spread internationally: former EIS officers on the staff of the Centers for Disease Control have helped to establish nearly thirty similar programs around the world. EIS veterans have gone on to become leaders in the world of public health in organizations such as the World Health Organization."Inside the Outbreaks" takes readers on a riveting journey through the history of this remarkable organization, following Epidemic Intelligence Service officers on their globetrotting quest to eliminate the most lethal and widespread threats to the world's health.

    With extensive treatment of the heart of epidemiology-from study designs to descriptive epidemiology to quantitative measures-this reader-friendly text is accessible and interesting to a wide range of beginning students in all health-related disciplines. A unique focus is given to real-world applications of epidemiology and the development of skills that students can apply in subsequent course work and in the field. The text is also accompanied by a complete package of instructor and student resources available through a companion Web site.

    America faced a troubling question: What happened? How was this epidemic allowed to spread so far before it was taken seriously? In answering these questions, Shilts weaves the disparate threads into a coherent story, pinning down every evasion and contradiction at the highest levels of the medical, political, and media establishments. Shilts shows that the epidemic spread wildly because the federal government put budget ahead of the nation's welfare; health authorities placed political expediency before the public health; and scientists were often more concerned with international prestige than saving lives. Against this backdrop, Shilts tells the heroic stories of individuals in science and politics, public health and the gay community, who struggled to alert the nation to the enormity of the danger it faced. And the Band Played On is both a tribute to these heroic people and a stinging indictment of the institutions that failed the nation so badly.

    But in fact, between animal welfare and conservation science there exists a space of underexamined and unresolved tension: wildness itself. When is it right to capture or feed wild animals for the good of their species? How do we balance the rights of introduced species with those already established within an ecosystem? Can hunting be ecological? Are any animals truly wild on a planet that humans have so thoroughly changed? No clear guidelines yet exist to help us resolve such questions.Transporting readers into the field with scientists tackling these profound challenges, Emma Marris tells the affecting and inspiring stories of animals around the globe-from Peruvian monkeys to Australian bilbies, rare Hawai'ian birds to majestic Oregon wolves. And she offers a companionable tour of the philosophical ideas that may steer our search for sustainability and justice in the non-human world. Revealing just how intertwined animal life and human life really are, Wild Souls will change the way we think about nature-and our place within it.

    Despite dire warnings and escalating concern over the state of our planet, many people feel out of touch with the natural world. Nobel laureate Wangari Maathai has spent decades working with the Green Belt Movement to help women in rural Kenya plant—and sustain—millions of trees. With their hands in the dirt, these women often find themselves empowered and “at home” in a way they never did before. Maathai wants to impart that feeling to everyone, and believes that the key lies in traditional spiritual values: love for the environment, self-betterment, gratitude and respect, and a commitment to service. While educated in the Christian tradition, Maathai draws inspiration from many faiths, celebrating the Jewish mandate tikkun olam (“repair the world”) and renewing the Japanese term mottainai (“don’t waste”). Through rededication to these values, she believes, we might finally bring about healing for ourselves and the earth.

    Spelling and grammar errors go unseen after numerous reading. But then, as Bones might say, Jim, I'm a doctor, not an editor.

    Where the color green calms us, and the forest sharpens our senses.In The Heartbeat of Trees, renowned forester Peter Wohlleben draws on new scientific discoveries to show how humans are deeply connected to the natural world.In an era of cell phone addiction, climate change, and urban life, many of us fear we've lost our connection to nature--but Peter Wohlleben is convinced that age-old ties linking humans to the forest remain alive and intact.Drawing on science and cutting-edge research, The Heartbeat of Trees reveals the profound interactions humans can have with nature, exploring:the language of the forestthe consciousness of plantsand the eroding boundary between flora and fauna.A perfect book to take with you into the woods, The Heartbeat of Trees shares how to see, feel, smell, hear, and even taste the forest.Peter Wohlleben, renowned for his ability to write about trees in an engaging and moving way, reveals a wondrous cosmos where humans are a part of nature, and where conservation and environmental activism is not just about saving trees--it's about saving ourselves, too.Praise for The Heartbeat of Trees "As human beings, we're desperate to feel that we're not alone in the universe. And yet we are surrounded by an ongoing conversation that we can sense if, as Peter Wohlleben so movingly prescribes, we listen to the heartbeat of all life." --Richard Louv, author of Our Wild Calling a nd Last Child in the Woods "Astonishment after astonishment--that is the great gift of The Heartbeat of Trees. It is both a celebration of the wonders of trees, and a howl of outrage at how recklessly we profane them." --Kathleen Dean Moore, author of Earth's Wild Music "As Peter Wohlleben reminds us in The Heartbeat of Trees, trees are the vocabulary of nature as forests are the brainbank of a living planet. This was the codex of the ancient world, and it must be the fine focus of our future." --Dr. Diana Beresford-Kroeger, author of To Speak for the Trees and The Global Forest "Peter Wohlleben knows the battle that lies before us: forging a closer relationship with nature before we destroy it. In The Heartbeat of Trees he takes us deep into the global forest to show us how."--Jim Robbins, author of The Man Who Planted Trees

    The term “complexity” can be misleading, however, because what makes West’s discoveries so beautiful is that he has found an underlying simplicity that unites the seemingly complex and diverse phenomena of living systems, including our bodies, our cities and our businesses. Fascinated by issues of aging and mortality, West applied the rigor of a physicist to the biological question of why we live as long as we do and no longer. The result was astonishing, and changed science, creating a new understanding of energy use and metabolism: West found that despite the riotous diversity in the sizes of mammals, they are all, to a large degree, scaled versions of each other. If you know the size of a mammal, you can use scaling laws to learn everything from how much food it eats per day, what its heart-rate is, how long it will take to mature, its lifespan, and so on. Furthermore, the efficiency of the mammal’s circulatory systems scales up precisely based on weight: if you compare a mouse, a human and an elephant on a logarithmic graph, you find with every doubling of average weight, a species gets 25% more efficient—and lives 25% longer. This speaks to everything from how long we can expect to live to how many hours of sleep we need. Fundamentally, he has proven, the issue has to do with the fractal geometry of the networks that supply energy and remove waste from the organism's body. West's work has been game-changing for biologists, but then he made the even bolder move of exploring his work's applicability to cities. Cities, too, are constellations of networks and laws of scalability relate with eerie precision to them. For every doubling in a city's size, the city needs 15% less road, electrical wire, and gas stations to support the same population. More amazingly, for every doubling in size, cities produce 15% more patents and more wealth, as well as 15% more crime and disease. This broad pattern lays the groundwork for a new science of cities. Recently, West has applied his revolutionary work on cities and biological life to the business world. This investigation has led to powerful insights into why some companies thrive while others fail. The implications of these discoveries are far-reaching, and are just beginning to be explored. Scale is a thrilling scientific adventure story about the elemental natural laws that bind us together in simple but profound ways. Through the brilliant mind of Geoffrey West, we can envision how cities, companies and biological life alike are dancing to the same simple, powerful tune, however diverse and unrelated they are to each other.From the Hardcover edition.

    Through serendipity— by chewing, brewing, and snorting—some Neolithic souls discovered opium, alcohol, snakeroot, juniper, frankincense, and other helpful substances. Ötzi the Iceman, the five-thousand-year-old hunter frozen in the Italian Alps, was found to have whipworms in his intestines and Bronze-age medicine, a worm-killing birch fungus, knotted to his leggings. Nowadays, Big Pharma conglomerates spend billions of dollars on state-of the art laboratories staffed by PhDs to discover blockbuster drugs. Yet, despite our best efforts to engineer cures, luck, trial-and-error, risk, and ingenuity are still fundamental to medical discovery.The Drug Hunters is a colorful, fact-filled narrative history of the search for new medicines from our Neolithic forebears to the professionals of today, and from quinine and aspirin to Viagra, Prozac, and Lipitor. The chapters offer a lively tour of how new drugs are actually found, the discovery strategies, the mistakes, and the rare successes. Dr. Donald R. Kirsch infuses the book with his own expertise and experiences from thirty-five years of drug hunting, whether searching for life-saving molecules in mudflats by Chesapeake Bay or as a chief science officer and research group leader at major pharmaceutical companies.