On Instagram, his uproarious videos have entertained millions and have made him a global celebrity. Now, he brings his bon vivance to the page with this collection of intimate and sassy essays.Bursting with color and life, dripping with his puckish Southern charm, How Y’all Doing? is Leslie doing what Leslie does best: telling stories that make us laugh and lift our spirits even in the darkest days. Whether he’s writing about his brush with a group of ruffians in a West Hollywood Starbucks, or an unexpected phone call from legendary Hollywood start Debbie Reynolds, Leslie infuses each story with his fresh and saucy humor and pure heart.How Y’all Doing? is an authentic, warm, and joyful portrait of an American Sweetheart— a Southern Baptist celebutante, first-rate raconteur, and keen observer of the odd side of life whose quirky wit rivals the likes of Amy Sedaris, Jenny Lawson, David Rakoff, and Sarah Vowell.

    Your brain can't function. You are asked to make decisions about treatment almost immediately, when you are not in your right mind. And yet you pull yourself together and start asking questions. Beside you is your doctor, whose job it is to solve the awful puzzle of bone marrow gone wrong. The two of you are in it together. In When Blood Breaks Down, Mikkael Sekeres, a leading cancer specialist, takes readers on the journey that patient and doctor travel together.Sekeres, who writes regularly for the Well section of the New York Times, tells the compelling stories of three people who receive diagnoses of adult leukemia within hours of each other: Joan, a 48-year-old surgical nurse, a caregiver who becomes a patient; David, a 68-year-old former factory worker who bows to his family's wishes and pursues the most aggressive treatment; and Sarah, a 36-year-old pregnant woman who must decide whether to undergo chemotherapy and put her fetus at risk. We join the intimacy of the conversations Sekeres has with his patients, and watch as he teaches trainees. Along the way, Sekeres also explores leukemia in its different forms and the development of drugs to treat it--describing, among many other fascinating details, the invention of the bone marrow transplant (first performed experimentally on beagles) and a treatment that targets the genetics of leukemia.The lessons to be learned from leukemia, Sekeres shows, are not merely medical; they teach us about courage and grace and defying the odds.

    Fate landed her at a wildlife sanctuary on the edge of the Amazon jungle where she was assigned to a beautiful and complex puma named Wayra. Wide-eyed, inexperienced, and comically terrified, Laura made the scrappy, make-do camp her home. And in Wayra, she made a friend for life.They weren’t alone, not with over a hundred quirky animals to care for, each lost and hurt in its own way: a pair of suicidal, bra-stealing monkeys, a frustrated parrot desperate to fly, and a pig with a wicked sense of humor. The humans, too, were cause for laughter and tears. There were animal whisperers, committed staff, wildly devoted volunteers, handsome heartbreakers, and a machete-wielding prom queen who carried Laura through. Most of all, there were the jungle—lyrical and alive—and Wayra, who would ultimately teach Laura so much about love, healing, and the person she was capable of becoming.Set against a turbulent and poignant backdrop of deforestation, the illegal pet trade, and forest fires, The Puma Years explores what happens when two desperate creatures in need of rescue find one another.

    Karen, Cathy, Angela, Sally, Diana. Sheila. Meet the Ames Girls: eleven childhood friends who formed a special bond growing up in Ames, Iowa. As young women, they moved to eight different states, yet managed to maintain an enduring friendship that would carry them through college and careers, marriage and motherhood, dating and divorce, a child’s illness and the mysterious death of one member of their group. Capturing their remarkable story, The Girls from Ames is a testament to the deep bonds of women as they experience life’s joys and challenges — and the power of friendship to triumph over heartbreak and unexpected tragedy.The girls, now in their forties, have a lifetime of memories in common, some evocative of their generation and some that will resonate with any woman who has ever had a friend. Photograph by photograph, recollection by recollection, occasionally with tears and often with great laughter, their sweeping and moving story is shared by Jeffrey Zaslow, Wall Street Journal columnist, as he attempts to define the matchless bonds of female friendship. It demonstrates how close female relationships can shape every aspect of women’s lives – their sense of themselves, their choice of men, their need for validation, their relationships with their mothers, their dreams for their daughters – and reveals how such friendships thrive, rewarding those who have committed to them.The Girls from Ames is the story of a group of ordinary women who built an extraordinary friendship. With both universal insights and deeply personal moments, it is a book that every woman will relate to and be inspired by.

    The winner of seven Olympic medals and the most decorated gymnast, male or female, in U.S. history, Shannon tells a story of surviving and thriving. A shy, rambunctious girl raised in Oklahoma, Shannon fell in love with gymnastics at a young age and fought her way to the top.In 1992 she won five Olympic medals after breaking her elbow in a training accident just months prior to the Games. Then, in 1996, a doctor advised her to retire immediately or face dire consequences if she chose to compete on her injured wrist. Undeterred, Shannon endured the pain and led her team, the "Magnificent Seven," to the first Olympic team gold medal for the United States in gymnastics. She followed up as the first American to win gold on the balance beam.Equally intense, heroic and gratifying is the story of her brutal but successful battle with ovarian cancer, a disease from which fewer than fifty percent survive. Relying on her faith and hard-learned perseverance, Shannon battled through surgery and major chemotherapy to emerge on the other side with a miracle baby girl.Her story of trial, triumph and life after cancer reminds us all that its life's bumps and bruises that reveal our character. From early on in her career, Shannon knew that life wasn't about perfection. In this incredible and inspirational tale, Shannon speaks out so as to be seen and heard by thousands as a beacon of hope.

    Though the world at first recoiled at the notion of a woman studying medicine, her intelligence and intensity ultimately won her the acceptance of the male medical establishment. In 1849, she became the first woman in America to receive an M.D. She was soon joined in her iconic achievement by her younger sister, Emily, who was actually the more brilliant physician.Exploring the sisters’ allies, enemies, and enduring partnership, Janice P. Nimura presents a story of trial and triumph. Together, the Blackwells founded the New York Infirmary for Indigent Women and Children, the first hospital staffed entirely by women. Both sisters were tenacious and visionary, but their convictions did not always align with the emergence of women’s rights—or with each other. From Bristol, Paris, and Edinburgh to the rising cities of antebellum America, this richly researched new biography celebrates two complicated pioneers who exploded the limits of possibility for women in medicine. As Elizabeth herself predicted, "a hundred years hence, women will not be what they are now."

    Water pours from the faucet in crystalline patterns, numbers call to mind distinct geometric shapes, and intricate fractal patterns emerge from the movement of tree branches, revealing the intrinsic mathematical designs hidden in the objects around us.Yet Padgett wasn’t born this way. Twelve years ago, he had never made it past pre-algebra. But a violent mugging forever altered the way his brain works, giving him unique gifts. His ability to understand math and physics skyrocketed, and he developed the astonishing ability to draw the complex geometric shapes he saw everywhere. His stunning, mathematically precise artwork illustrates his intuitive understanding of complex mathematics.The first documented case of acquired savant syndrome with mathematical synesthesia, Padgett is a medical marvel. Struck by Genius recounts how he overcame huge setbacks and embraced his new mind. Along the way he fell in love, found joy in numbers, and spent plenty of time having his head examined. Like Born on a Blue Day and My Stroke of Insight, his singular story reveals the wondrous potential of the human brain.www.struckbygenius.com

    Why cope with insecurities I don't already have?That last one's just me? All right, then.But if the rest sounds familiar, you are experiencing Girl Logic: a characteristically female way of thinking that appears contradictory and circuitous but is actually a complicated and highly evolved way of looking at the world. You end up considering every repercussion of every choice (about dating, career, clothes, lunch) before making a move toward what you really want. And why do we attempt these mental hurdles? Well, that's what this book is all about.The fact is, whether you're obsessing over his last text or the most important meeting of your career, your Girl Logic serves a purpose: It helps push you, question what you want, and clarify what will make you a happier, better person. Girl Logic can be every confident woman's secret weapon, and this book shows you how to wield it.

    That simple act became a national news story because Abby was the director of a Planned Parenthood clinic in Texas who, after participating in her first actual abortion procedure, walked across the road to join the Coalition for Life. "Unplanned" is a heartstopping personal drama of life-and-death encounters, a courtroom battle, and spiritual transformation that speaks hope and compassion into the political controversy that surrounds this issue. Telling Abby’s story from both sides of the abortion clinic property line, this book is a must-read for anyone who cares about the life versus rights debate and helping women who face crisis pregnancies.

    Conley, the first female tenured professor of neurosurgery in the country, made headline news when she resigned from Stanford University to protest the medical school's unabashed gender discrimination. In this controversial, forthright memoir, Conley portrays the world of academic medicine in which women are still considered inferior; she also explains why, as a consequence, the research and treatment of women's health problems lag far behind those of men. In assessing why women's careers and psyches are suffering, Conley provides a first-person look into what it is like to be an accomplished woman within this restrictive medical world, offering invaluable advice to patients and future doctors alike.

    It includes a brief introduction describing the evolution of Mark Twain’s ideas about writing his autobiography, as well as a chronology of his life, brief family biographies, and an excerpt from the forthcoming Autobiography of Mark Twain, Volume 2—a controversial but characteristically humorous attack on Christian doctrine.The year 2010 marked the 100th anniversary of Mark Twain’s death. In celebration of this important milestone and in honor of the cherished tradition of publishing Mark Twain’s works, UC Press published Autobiography of Mark Twain, Volume 1, the first of a projected three-volume edition of the complete, uncensored autobiography. The book became an immediate bestseller and was hailed as the capstone of the life’s work of America’s favorite author.Read an excerpt here: Autobiography of Mark Twain, Volume 1:The Complete and Authoritative Edition by Mark Twain by University of California Press

    It’s a fly-on-the-wall account of the titanic fight to pass a 961-page law aimed at fixing America’s largest, most dysfunctional industry. It’s a penetrating chronicle of how the profiteering that Brill first identified in his trailblazing Time magazine cover story continues, despite Obamacare. And it is the first complete, inside account of how President Obama persevered to push through the law, but then failed to deal with the staff incompetence and turf wars that crippled its implementation.   But by chance America’s Bitter Pill ends up being much more—because as Brill was completing this book, he had to undergo urgent open-heart surgery. Thus, this also becomes the story of how one patient who thinks he knows everything about healthcare “policy” rethinks it from a hospital gurney—and combines that insight with his brilliant reporting. The result: a surprising new vision of how we can fix American healthcare so that it stops draining the bank accounts of our families and our businesses, and the federal treasury. Praise for America’s Bitter Pill   “A tour de force . . . a comprehensive and suitably furious guide to the political landscape of American healthcare . . . persuasive, shocking.”—The New York Times   “An energetic, picaresque, narrative explanation of much of what has happened in the last seven years of health policy . . . [Brill] has pulled off something extraordinary.” —The New York Times Book Review   “A thunderous indictment of what Brill refers to as the ‘toxicity of our profiteer-dominated healthcare system.’ ”—Los Angeles Times  “A sweeping and spirited new book [that] chronicles the surprisingly juicy tale of reform.”—The Daily Beast  “One of the most important books of our time.”—Walter Isaacson   “Superb . . . Brill has achieved the seemingly impossible—written an exciting book about the American health system.”—The New York Review of Books

    She takes a once-in-a-lifetime chance and joins a clinical trial for immunotherapy, a revolutionary drug regimen that trains the body to vanquish malignant cells. Astonishingly, her cancer disappears entirely in just a few weeks. But at the same time, her best friend embarks on a cancer journey of her own--with very different results. Williams's experiences as a patient and a medical test subject reveal with stark honesty what it takes to weather disease, the extraordinary new developments that are rewriting the rules of science--and the healing power of human connection.

    She had no relatives left, she'd lost her family farm to back taxes, and her doctor had just given her two years to live--but only if she lived restfully. He offered her a spot in the county's charity home. Instead, she decided she wanted to see the Pacific Ocean just once before she died. She bought a cast-off brown gelding named Tarzan, donned men's dungarees, loaded up her horse, and headed out from Maine in mid-November, hoping to beat the snow. She had no map, no GPS, no phone. But she had her ex-racehorse, her faithful mutt, and her own unfailing belief that Americans would treat a stranger with kindness.Between 1954 and 1956, Annie, Tarzan, and her dog, Depeche Toi, journeyed more than 4,000 miles, through America's big cities and small towns, meeting ordinary people and celebrities--from Andrew Wyeth (who sketched Tarzan) to Art Linkletter and Groucho Marx. She received many offers--a permanent home at a riding stable in New Jersey, a job at a gas station in rural Kentucky, even a marriage proposal from a Wyoming rancher who loved animals as much as she did. As Annie trudged through blizzards, forded rivers, climbed mountains, and clung to the narrow shoulder as cars whipped by her at terrifying speeds, she captured the imagination of an apprehensive Cold War America. At a time when small towns were being bypassed by Eisenhower's brand-new interstate highway system, and the reach and impact of television was just beginning to be understood, Annie and her four-footed companions inspired an outpouring of neighborliness in a rapidly changing world.

    When he emerged he had under his arm a manuscript, a genre-smashing book about comedy, tragedy, love, loss, war, and redemption. When asked if this was the celebrity memoir, Norm replied, "Call it anything you damn like."