Six eager interns—they saw themselves as modern saviors-to-be.   They came from the top of their medical school class  to the bottom of the hospital staff to serve a  year in the time-honored tradition, racing to answer  the flash of on-duty call lights and nubile  nurses. But only the Fat Man—the Clam, all-knowing resident—could sustain them in their struggle to survive, to stay sane, to love and even to be doctors when their harrowing year was done.

    These “psychosurgeons,” as they called themselves, occupied a gray zone between medical research and medical practice, and ended up subjecting untold numbers of people to the types of surgical experiments once limited to chimpanzees.The most important test subject to emerge from this largely untold chapter in American history was a twenty-seven-year-old factory worker named Henry Molaison. In 1953, Henry—who suffered from severe epilepsy—received a radical new version of the lobotomy, one that targeted the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry left the operating room profoundly amnesic, unable to create new long-term memories. Over the next sixty years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.Luke Dittrich uses the case of Patient H.M. as a starting point for a kaleidoscopic journey, one that moves from the first recorded brain surgeries in ancient Egypt to the cutting-edge laboratories of MIT. He takes readers inside the old asylums and operating theaters where psychosurgeons conducted their human experiments, and behind the scenes of a bitter custody battle over the ownership of the most important brain in the world. Throughout, Dittrich delves into the enduring mysteries of the mind while exposing troubling stories of just how far we’ve gone in our pursuit of knowledge. It is also, at times, a deeply personal journey. Dittrich’s grandfather was the brilliant, morally complex surgeon who operated on Molaison—and thousands of other patients. The author’s investigation into the dark roots of modern memory science ultimately forces him to confront unsettling secrets in his own family history, and to reveal the tragedy that fueled his grandfather’s relentless experimentation—experimentation that would revolutionize our understanding of ourselves.Patient H.M. combines the best of biography, memoir, and science journalism to create a haunting, endlessly fascinating story, one that reveals the wondrous and devastating things that can happen when hubris, ambition, and human imperfection collide.

    In this sensational and macabre story, we meet the surgeon who counted not only luminaries Benjamin Franklin, Lord Byron, Adam Smith, and Thomas Gainsborough among his patients but also “resurrection men” among his close acquaintances. A captivating portrait of his ruthless devotion to uncovering the secrets of the human body, and the extraordinary lengths to which he went to do so—including body snatching, performing pioneering medical experiments, and infecting himself with venereal disease—this rich historical narrative at last acknowledges this fascinating man and the debt we owe him today.

    Not long after, she also became mute. Her tenacious struggle to overcome these handicaps-with the help of her inspired teacher, Anne Sullivan-is one of the great stories of human courage and dedication. In this classic autobiography, first published in 1903, Miss Keller recounts the first 22 years of her life, including the magical moment at the water pump when, recognizing the connection between the word "water" and the cold liquid flowing over her hand, she realized that objects had names. Subsequent experiences were equally noteworthy: her joy at eventually learning to speak, her friendships with Oliver Wendell Holmes, Edward Everett Hale and other notables, her education at Radcliffe (from which she graduated cum laude), and-underlying all-her extraordinary relationship with Miss Sullivan, who showed a remarkable genius for communicating with her eager and quick-to-learn pupil.

    individual whose contributions to the scientific, business and cultural realms are extensive."—BookpageBefore slim laptops that fit into briefcases, computers looked like strange, alien vending machines. But in "the most staggering burst of technical invention by a single person in high-tech history" (BusinessWeek​) Steve Wozniak invented the first true personal computer. Wozniak teamed up with Steve Jobs, and Apple Computer was born, igniting the computer revolution and transforming the world. Here, thirty years later, the mischievous genius with the low profile treats readers to a rollicking, no-holds-barred account of his life—for once, in the voice of the wizard himself.

    Perry Baird was a rising medical star in the late 1920s and 1930s. Early in his career, ahead of his time, he grew fascinated with identifying the biochemical root of manic depression, just as he began to suffer from it himself. By the time the results of his groundbreaking experiments were published, Dr. Baird had been institutionalized multiple times, his medical license revoked, and his wife and daughters estranged. He later received a lobotomy and died from a consequent seizure, his research incomplete, his achievements unrecognized.Mimi Baird grew up never fully knowing this story, as her family went silent about the father who had been absent for most of her childhood. Decades later, a string of extraordinary coincidences led to the recovery of a manuscript which Dr. Baird had worked on throughout his brutal institutionalization, confinement, and escape. This remarkable document, reflecting periods of both manic exhilaration and clear-headed health, presents a startling portrait of a man who was a uniquely astute observer of his own condition, struggling with a disease for which there was no cure, racing against time to unlock the key to treatment before his illness became impossible to manage.Fifty years after being told her father would forever be “ill” and “away,” Mimi Baird set off on a quest to piece together the memoir and the man. In time her fingers became stained with the lead of the pencil he had used to write his manuscript, as she devoted herself to understanding who he was, why he disappeared, and what legacy she had inherited. The result of his extraordinary record and her journey to bring his name to light is He Wanted the Moon, an unforgettable testament to the reaches of the mind and the redeeming power of a determined heart.Soon to be a major motion picture, from Brad Pitt and Tony Kushner

    With a hundred dollars in his pocket, a beat up cavalry saddle, and a faraway look in his eye, John Egenes saddled his horse Gizmo and started down the trail on an adventure across the North American continent. Their seven month journey took them across 11 states from California to Virginia, ocean to ocean.. As they left the pressing confinement of the city behind them, the pair experienced the isolation and loneliness of the southwestern deserts, the vastness of the prairie, and the great landscapes that make up America. Across hundreds of miles of empty land they slept with coyotes and wild horses under the stars, and in urban areas they camped alone in graveyards and abandoned shacks. Along the way John and Gizmo were transformed from inexperienced horse and rider to veterans of the trail. With his young horse as his spiritual guide John slowly began to comprehend his own place in the world and to find peace within himself. Full of heart and humor, Egenes serves up a tale that's as big as the America he witnessed, an America that no longer exists. It was a journey that could only have been experienced step by step, mile by mile, from the view between a horse's ears.

    Featuring many photographs, this book also candidly recounts a gifted and celebrated writer's descent into the life of alcohol and drugs that would ultimately consume his bulldog spirit and staggering talent--but not before he'd hobnob with the likes of Grace Paley and Lee Radziwill, feud outrageously with Gore Vidal and Jacqueline Susann, and stage at New York's Plaza Hotel the sensational Black and White Ball.

    Q, an internationally renowned neurosurgeon and neuroscientist who leads cutting-edge research to cure brain cancer. But not too long ago, he was Freddy, a nineteen-year-old undocumented migrant worker toiling in the tomato fields of central California. In this gripping memoir, Alfredo Quiñones-Hinojosa tells his amazing life story—from his impoverished childhood in the tiny village of Palaco, Mexico, to his harrowing border crossing and his transformation from illegal immigrant to American citizen and gifted student at the University of California at Berkeley and at Harvard Medical School. Packed with adventure and adversity—including a few terrifying brushes with death—Becoming Dr. Q is a testament to persistence, hard work, the power of hope and imagination, and the pursuit of excellence. It’s also a story about the importance of family, of mentors, and of giving people a chance.

    The emotional, incredible true story of Neil White, a man who discovers the secret to happiness, leading a fulfilling life, and the importance of fatherhood in the most unlikely of places—the last leper colony in the continental United States.

    Trust Me, I'm a (Junior) Doctor In the vein of the best 'blog books' - the real life story of a hapless junior doctor, based on his columns written anonymously for the Telegraph Full description

    It was into this world that Jennifer Worth entered as a trainee midwife. But life was tough, and babies were often born in slum conditions.In Call The Midwife, Shadows Of The Workhouse and Farewell To The East End, Jennifer recounts her time among nuns, prostitutes, abortionists, bigamists, gangsters and expectant mothers, eloquently portraying the East Enders' amazing resilience, their warmth and humour in the face of hardship, and the traditions and tales of a bygone era.

    Doctor, Harvard professor, renowned infectious-disease specialist, anthropologist, the recipient of a MacArthur "genius" grant, world-class Robin Hood, Farmer was brought up in a bus and on a boat, and in medical school found his life’s calling: to diagnose and cure infectious diseases and to bring the lifesaving tools of modern medicine to those who need them most.Mountains Beyond Mountains takes us from Harvard to Haiti, Peru, Cuba, and Russia as Farmer changes minds and practices through his dedication to the philosophy that "the only real nation is humanity"—a philosophy that is embodied in the small public charity he founded, Partners in Health. He enlists the help of the Gates Foundation, George Soros, the U.N.’s World Health Organization, and others in his quest to cure the world. At the heart of this book is the example of a life based on hope, and on an understanding of the truth of the Haitian proverb "Beyond mountains there are mountains": as you solve one problem, another problem presents itself, and so you go on and try to solve that one too.

    In this Penguin Classics edition, the letters are selected and edited by Ronald de Leeuw, and translated by Arnold Pomerans in Penguin Classics.Few artists' letters are as self-revelatory as Vincent van Gogh's, and this selection, spanning his artistic career, sheds light on every facet of the life and work of this complex and tortured man. Engaging candidly and movingly with his religious struggles, his ill-fated search for love, his attacks of mental illness and his relation with his brother Theo, the letters contradict the popular myth of van Gogh as an anti-social madman and a martyr to art, showing instead a man of great emotional and spiritual depths. Above all, they stand as an intense personal narrative of artistic development and a unique account of the process of creation.The letters are linked by explanatory biographical passages, revealing van Gogh's inner journey as well as the outer facts of his life. This edition also includes the drawings that originally illustrated the letters.Vincent Willem van Gogh (1853-1890) was born in Holland. In 1885 he painted his first masterpiece, The Potato Eaters, a haunting scene of domestic poverty. A year later he began studying in Paris, where he met Gauguin, Toulouse-Lautrec and Seurat, who became very important influences on his work. In 1888 he left Paris for the Provencal landscape at Arles, the subject of many of his best works, including Sunflowers.If you enjoyed The Letters of Vincent van Gogh, you might also like 100 Artists Manifestos, available in Penguin Modern Classics.'If there was ever any doubt that Van Gogh's letters belong beside those great classics of artistic self-revelation, Cellini's autobiography and Delacroix's journal, this excellent new edition dispels it'The Times

    What she did not count on was how much death would be a part of her work. Almost immediately, Chen found herself wrestling with medicine’s most profound paradox, that a profession premised on caring for the ill also systematically depersonalizes dying. Final Exam follows Chen over the course of her education, training, and practice as she grapples at strikingly close range with the problem of mortality, and struggles to reconcile the lessons of her training with her innate knowledge of shared humanity, and to separate her ideas about healing from her fierce desire to cure.From her first dissection of a cadaver in gross anatomy to the moment she first puts a scalpel to a living person; from the first time she witnesses someone flatlining in the emergency room to the first time she pronounces a patient dead, Chen is struck by her own mortal fears: there was a dying friend she could not call; a young patient’s tortured death she could not forget; even the sense of shared kinship with a corpse she could not cast aside when asked to saw its pelvis in two. Gradually, as she confronts the ways in which her fears have incapacitated her, she begins to reject what she has been taught about suppressing her feelings for her patients, and she begins to carve out a new role for herself as a physician and as human being. Chen’s transfixing and beautiful rumination on how doctors negotiate the ineluctable fact of death becomes, in the end, a brilliant questioning of how we should live.Moving and provocative, motored equally by clinical expertise and extraordinary personal grace, this is a piercing and compassionate journey into the heart of a world that is hidden and yet touches all of our lives. A superb addition to the best medical literature of our time.