They are the powerhouses of our cells, essential for the production and management of energy at cell level. Dr Sarah Myhill, together with Dr John McLaren Howard of Acumen Laboratories and Dr Norman Booth of Mansfield College Oxford, has spent many years studying the relationship between their malfunction and the commonest problem seen by GPs in the UK – fatigue. Their research findings have been published in three scientific papers in the International Journal of Clinical and Experimental Medicine, in 2009, 2012 and 2013. These studies showed that poor functioning of the mitochondria is the central problem in CFS. Patients with the worst mitochondrial function had the worst fatigue and vice versa. This is solid scientific evidence that CFS is a problem with mitochondria and has allowed the objective measurement of fatigue for the first time. With the publication of the third study, which showed that mitochondrial function tests and symptoms improved in patients who took measures to address their mitochondrial problems, Dr Myhill was ready to write this book. Here she explains the importance of healthy mitochondria, how we can measure their functioning and what we can do to keep them healthy, or restore them to health if problems arise. CFS is all in our cells, not in our minds!

    Revised to reflect the latest research in the field, this book emphasizes the relationships and concepts that link cell and tissue structures with their functions. A bonus image library CD-ROM featuring all the photos and illustrations from the text with "zoom in" and "zoom out" capability is also included.

    This time physicist Robert Gilmore takes us on a journey with Dorothy, following the yellow building block road through the land of the Wizard of Quarks. Using characters and situations based on the Wizard of Oz story, we learn along the way about the fascinating world of particle physics. Classes of particles, from quarks to leptons are shown in an atomic garden, where atoms and molecules are produced. See how Dorothy, The Tin Geek, and the Cowardly Lion experience the bizarre world of subatomic particles.

    Evolutionary Dynamics is concerned with these equations of life. In this book, Martin A. Nowak draws on the languages of biology and mathematics to outline the mathematical principles according to which life evolves. His work introduces readers to the powerful yet simple laws that govern the evolution of living systems, no matter how complicated they might seem. Evolution has become a mathematical theory, Nowak suggests, and any idea of an evolutionary process or mechanism should be studied in the context of the mathematical equations of evolutionary dynamics. His book presents a range of analytical tools that can be used to this end: fitness landscapes, mutation matrices, genomic sequence space, random drift, quasispecies, replicators, the Prisoner's Dilemma, games in finite and infinite populations, evolutionary graph theory, games on grids, evolutionary kaleidoscopes, fractals, and spatial chaos. Nowak then shows how evolutionary dynamics applies to critical real-world problems, including the progression of viral diseases such as AIDS, the virulence of infectious agents, the unpredictable mutations that lead to cancer, the evolution of altruism, and even the evolution of human language. His book makes a clear and compelling case for understanding every living system--and everything that arises as a consequence of living systems--in terms of evolutionary dynamics.

    Converging findings from a variety of disciplines are leading to the emergence of a fundamentally new view of the human mind, and with it a new framework for the behavioral and social sciences. First, with the advent of the cognitive revolution, human nature can finally be defined precisely as the set of universal, species-typical information-processing programs that operate beneath the surface of expressed cultural variability. Second, this collection of cognitive programs evolved in the Pleistocene to solve the adaptive problems regularly faced by our hunter-gatherer ancestors--problems such as mate selection, language acquisition, cooperation, and sexual infidelity. Consequently, the traditional view of the mind as a general-purpose computer, tabula rasa, or passive recipient of culture is being replaced by the view that the mind resembles an intricate network of functionally specialized computers, each of which imposes contentful structure on human mental organization and culture. The Adapted Mind explores this new approach--evolutionary psychology--and its implications for a new view of culture.

    Is it science? Is it religion? What exactly is the Design Revolution? Today scientists, mathematicians and philosophers in the intelligent design movement are challenging a certain view of science--one that limits its investigations and procedures to purely law-like and mechanical explanations. They charge that there is no scientific reason to exclude the consideration of intelligence, agency and purpose from truly scientific research. In fact, they say, the practice of science often does already include these factors! As the intelligent design movement has gained momentum, questions have naturally arisen to challenge its provocative claims. In this book William A. Dembski rises to the occasion clearly and concisely answering the most vexing questions posed to the intelligent design program. Writing with nonexperts in mind, Dembski responds to more than sixty questions asked by experts and nonexperts alike who have attended his many public lectures, as well as objections raised in written reviews. The Design Revolution has begun. Its success depends on how well it answers the questions of its detractors. Read this book and you'll have a good idea of the prospects and challenges facing this revolution in scientific thinking.

    Did humans emerge through evolutionary processes from an ape-like ancestor or are we God's creation? A comparison of scientific models provides stunning insights and a framework to test emerging evidence.